| 2/17/2025 | Stonepine Capital Management LLC | 588,657 | $3.93M | 3.2% | -89.7% | 5.851% | |
| 2/17/2025 | Millennium Management LLC | 12,854 | $86K | 0.0% | -98.0% | 0.128% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 333,333 | $2.23M | 0.0% | -93.3% | 3.313% | |
| 2/17/2025 | Bridgeway Capital Management LLC | 15,713 | $105K | 0.0% | -93.5% | 0.156% | |
| 2/17/2025 | Bleichroeder LP | 269,675 | $1.80M | 0.5% | -93.3% | 2.681% | |
| 2/17/2025 | Acorn Capital Advisors LLC | 422,813 | $2.82M | 1.5% | N/A | 4.203% | |
| 2/14/2025 | MVM Partners LLC | 973,684 | $6.36M | 5.1% | -93.3% | 9.679% | |
| 2/14/2025 | Jane Street Group LLC | 28,560 | $191K | 0.0% | -32.5% | 0.284% | |
| 2/14/2025 | Nantahala Capital Management LLC | 986,031 | $6.59M | 0.3% | -93.1% | 9.802% | |
| 2/14/2025 | Northern Trust Corp | 14,085 | $94K | 0.0% | -94.4% | 0.140% | |
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| 2/14/2025 | GMT Capital Corp | 74,047 | $495K | 0.0% | -93.3% | 0.736% | |
| 2/13/2025 | Renaissance Technologies LLC | 12,748 | $85K | 0.0% | -94.4% | 0.127% | |
| 2/13/2025 | Aster Capital Management DIFC Ltd | 3,898 | $26K | 0.0% | -93.3% | 0.039% | |
| 2/12/2025 | Geode Capital Management LLC | 86,167 | $576K | 0.0% | -93.4% | 0.857% | |
| 2/12/2025 | Easterly Investment Partners LLC | 46,667 | $312K | 0.0% | -98.0% | 0.464% | |
| 2/11/2025 | Rosalind Advisors Inc. | 876,996 | $5.86M | 2.9% | -89.4% | 8.718% | |
| 2/7/2025 | Prescott Group Capital Management L.L.C. | 60,139 | $402K | 0.1% | -95.2% | 0.598% | |
| 2/4/2025 | Bank of New York Mellon Corp | 12,178 | $81K | 0.0% | -93.3% | 0.121% | |
| 1/31/2025 | Rice Hall James & Associates LLC | 74,479 | $498K | 0.0% | -93.5% | 0.740% | |
| 1/1/2025 | Barclays PLC | 49,658 | $33K | 0.0% | -30.3% | 0.033% | |
| 11/16/2024 | Geode Capital Management LLC | 1,298,333 | $870K | 0.0% | +33.7% | 0.861% | |
| 11/15/2024 | Jane Street Group LLC | 42,314 | $28K | 0.0% | -88.7% | 0.028% | |
| 11/15/2024 | State Street Corp | 341,303 | $229K | 0.0% | +14.2% | 0.226% | |
| 11/14/2024 | Stonepine Capital Management LLC | 5,688,590 | $3.81M | 2.4% | +142.1% | 3.773% | |
| 11/13/2024 | Great Point Partners LLC | 12,861,136 | $8.62M | 2.5% | -6.3% | 8.530% | |
| 11/13/2024 | FMR LLC | 16,541,849 | $11.08M | 0.0% | +3.2% | 10.971% | |
| 11/12/2024 | Massachusetts Financial Services Co. MA | 3,075,638 | $2.06M | 0.0% | +5.3% | 2.040% | |
| 11/5/2024 | GSA Capital Partners LLP | 91,084 | $61K | 0.0% | N/A | 0.060% | |
| 11/1/2024 | Easterly Investment Partners LLC | 2,359,239 | $1.58M | 0.1% | +5.0% | 1.565% | |
| 10/30/2024 | Rosalind Advisors Inc. | 8,287,503 | $5.55M | 3.5% | +9.8% | 5.496% | |
| 10/28/2024 | Rice Hall James & Associates LLC | 1,140,626 | $764K | 0.0% | +15.4% | 0.756% | |
| 10/28/2024 | Palumbo Wealth Management LLC | 78,378 | $53K | 0.0% | -42.2% | 0.052% | |
| 8/21/2024 | Stonepine Capital Management LLC | 2,350,010 | $2.44M | 2.2% | N/A | 2.079% | |
| 8/20/2024 | Nantahala Capital Management LLC | 13,418,740 | $14.43M | 0.8% | +442.3% | 8.900% | |
| 8/14/2024 | Squarepoint Ops LLC | 171,610 | $178K | 0.0% | +173.7% | 0.152% | |
| 8/14/2024 | Great Point Partners LLC | 13,727,097 | $14.28M | 2.7% | +56.2% | 12.144% | |
| 8/12/2024 | XTX Topco Ltd | 84,504 | $88K | 0.0% | N/A | 0.075% | |
| 8/9/2024 | Renaissance Technologies LLC | 233,100 | $242K | 0.0% | -17.3% | 0.206% | |
| 8/9/2024 | Massachusetts Financial Services Co. MA | 2,920,309 | $3.04M | 0.0% | +2.9% | 2.583% | |
| 7/26/2024 | Bank of New York Mellon Corp | 182,685 | $190K | 0.0% | -48.8% | 0.162% | |
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| 7/25/2024 | Easterly Investment Partners LLC | 2,246,224 | $2.34M | 0.2% | +10.2% | 1.987% | |
| 7/18/2024 | Assenagon Asset Management S.A. | 76,185 | $79K | 0.0% | -12.5% | 0.067% | |
| 7/12/2024 | Rosalind Advisors Inc. | 7,547,148 | $7.85M | 5.7% | +66.2% | 6.677% | |
| 5/15/2024 | Oracle Investment Management Inc. | 325,000 | $474K | 0.3% | N/A | 0.288% | |
| 5/10/2024 | Vanguard Group Inc. | 4,242,610 | $6.19M | 0.0% | +1.5% | 3.753% | |
| 5/3/2024 | Easterly Investment Partners LLC | 2,038,039 | $2.98M | 0.2% | +34.0% | 1.803% | |
| 4/29/2024 | HighMark Wealth Management LLC | 25,000 | $36K | 0.0% | N/A | 0.022% | |
| 4/25/2024 | Rosalind Advisors Inc. | 4,541,489 | $6.63M | 6.2% | -7.0% | 4.032% | |
| 4/24/2024 | Assenagon Asset Management S.A. | 87,096 | $127K | 0.0% | +139.1% | 0.077% | |
| 4/23/2024 | Rice Hall James & Associates LLC | 993,268 | $1.45M | 0.1% | -1.2% | 0.882% | |
| 3/18/2024 | Kingdon Capital Management L.L.C. | 3,899,237 | $5.03M | 0.6% | +5.4% | 3.461% | |
| 2/12/2024 | MVM Partners LLC | 14,605,263 | $18.77M | 10.9% | N/A | 13.004% | |
| 1/22/2024 | Palumbo Wealth Management LLC | 25,959 | $33K | 0.0% | N/A | 0.023% | |
| 1/17/2024 | Assenagon Asset Management S.A. | 36,434 | $47K | 0.0% | N/A | 0.032% | |
| 11/15/2023 | Kingdon Capital Management L.L.C. | 3,699,237 | $4.55M | 0.5% | +1.4% | 3.294% | |
| 11/13/2023 | FMR LLC | 14,848,870 | $18.26M | 0.0% | +0.3% | 13.221% | |
| 11/7/2023 | New York State Common Retirement Fund | 47,832 | $59K | 0.0% | -41.2% | 0.043% | |
| 11/2/2023 | Rice Hall James & Associates LLC | 1,050,074 | $1.29M | 0.1% | +8.6% | 0.936% | |
| 10/24/2023 | Bank of New York Mellon Corp | 390,987 | $481K | 0.0% | +71.6% | 0.348% | |
| 8/14/2023 | Great Point Partners LLC | 8,839,939 | $10.87M | 2.1% | +12.0% | 7.886% | |
| 8/11/2023 | Velan Capital Investment Management LP | 3,596,861 | $4.42M | 4.1% | +2.9% | 3.213% | |
| 8/4/2023 | American International Group Inc. | 35,095 | $43K | 0.0% | N/A | 0.031% | |
| 7/27/2023 | Virtu Financial LLC | 32,949 | $41K | 0.0% | N/A | 0.029% | |
| 7/24/2023 | Rice Hall James & Associates LLC | 966,723 | $1.19M | 0.1% | +25.2% | 0.863% | |
| 6/1/2023 | Prelude Capital Management LLC | 156,946 | $303K | 0.0% | +5.9% | 0.140% | |
| 5/15/2023 | Kingdon Capital Management L.L.C. | 3,649,237 | $7.04M | 1.3% | +15.9% | 3.260% | |
| 5/12/2023 | Element Capital Management LLC | 331,135 | $639K | 0.0% | N/A | 0.296% | |
| 5/12/2023 | Rice Hall James & Associates LLC | 771,960 | $1.49M | 0.1% | -4.6% | 0.689% | |
| 5/9/2023 | GMT Capital Corp | 23,288 | $45K | 0.0% | N/A | 0.021% | |
| 5/9/2023 | Y Intercept Hong Kong Ltd | 19,040 | $37K | 0.0% | N/A | 0.017% | |
| 5/1/2023 | Arete Wealth Advisors LLC | 10,000 | $19.30B | 0.0% | N/A | 0.009% | |
| 2/15/2023 | Nantahala Capital Management LLC | 1,450,000 | $2.68M | 0.2% | N/A | 1.736% | |
| 2/14/2023 | Kingdon Capital Management L.L.C. | 3,149,237 | $5.83M | 1.2% | +37.0% | 3.771% | |
| 2/14/2023 | 683 Capital Management LLC | 102,528 | $190K | 0.0% | N/A | 0.123% | |
| 2/13/2023 | MVM Partners LLC | 14,605,263 | $26.80M | 9.1% | N/A | 17.487% | |
| 2/10/2023 | Prescott Group Capital Management L.L.C. | 130,000 | $240K | 0.1% | N/A | 0.156% | |
| 2/10/2023 | Cheyne Capital Management UK LLP | 394,737 | $730K | 1.3% | N/A | 0.473% | |
| 1/27/2023 | Rice Hall James & Associates LLC | 809,503 | $1.50M | 0.1% | -1.4% | 0.969% | |
| 11/14/2022 | Hsbc Holdings PLC | 25,914 | $94K | 0.0% | -15.5% | 0.031% | |
| 11/10/2022 | Stonepine Capital Management LLC | 2,000,000 | $7.32M | 3.3% | -23.6% | 2.402% | |
| 11/9/2022 | Massachusetts Financial Services Co. MA | 1,899,299 | $6.95M | 0.0% | +7.1% | 2.281% | |
| 11/9/2022 | Easterly Investment Partners LLC | 737,295 | $2.70M | 0.3% | +11.3% | 0.885% | |
| 11/7/2022 | Arete Wealth Advisors LLC | 12,000 | $44K | 0.0% | N/A | 0.014% | |
| 11/3/2022 | Barclays PLC | 54,153 | $198K | 0.0% | -14.1% | 0.065% | |
| 11/1/2022 | Rice Hall James & Associates LLC | 820,807 | $3.00M | 0.2% | -7.5% | 0.986% | |
| 8/24/2022 | Prelude Capital Management LLC | 150,000 | $549K | 0.0% | +20.0% | 0.180% | |
| 8/15/2022 | Opaleye Management Inc. | 90,970 | $333K | 0.2% | N/A | 0.110% | |
| 8/13/2022 | Massachusetts Financial Services Co. MA | 1,773,350 | $6.49M | 0.0% | -0.8% | 2.145% | |
| 8/12/2022 | FMR LLC | 12,402,156 | $45.39M | 0.0% | +0.3% | 15.000% | |
| 8/8/2022 | Walleye Capital LLC | 36,226 | $133K | 0.0% | N/A | 0.044% | |
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| 8/8/2022 | Rice Hall James & Associates LLC | 887,584 | $3.25M | 0.2% | +0.7% | 1.074% | |
| 7/27/2022 | Assenagon Asset Management S.A. | 16,911 | $62K | 0.0% | -80.3% | 0.020% | |
| 5/26/2022 | Rice Hall James & Associates LLC | 881,665 | $2.18M | 0.1% | +4.2% | 1.066% | |
| 5/16/2022 | Velan Capital Investment Management LP | 2,000,000 | $4.94M | 4.6% | N/A | 2.419% | |
| 5/11/2022 | Bleichroeder LP | 3,742,189 | $9.24M | 1.6% | +0.6% | 4.526% | |
| 5/11/2022 | Massachusetts Financial Services Co. MA | 1,787,258 | $4.42M | 0.0% | +2.9% | 2.162% | |
| 5/5/2022 | Rice Hall James & Associates LLC | 881,665 | $2.18M | 0.1% | +4.2% | 1.066% | |
| 4/25/2022 | Assenagon Asset Management S.A. | 85,642 | $212K | 0.0% | N/A | 0.104% | |
| 2/15/2022 | Stonepine Capital Management LLC | 3,844,230 | $6.23M | 2.9% | N/A | 4.677% | |
| 2/14/2022 | Rice Hall James & Associates LLC | 846,167 | $1.37M | 0.0% | -9.2% | 1.029% | |
