| 2/18/2025 | Frazier Life Sciences Management L.P. | 1,120,803 | $14.76M | 0.6% | N/A | 1.842% | |
| 2/17/2025 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 139,574 | $1.84M | 0.0% | +18.3% | 0.229% | |
| 2/17/2025 | Woodline Partners LP | 127,295 | $1.68M | 0.0% | +14.0% | 0.209% | |
| 2/17/2025 | Two Sigma Investments LP | 97,078 | $1.28M | 0.0% | -28.2% | 0.160% | |
| 2/17/2025 | Two Sigma Advisers LP | 135,700 | $1.79M | 0.0% | -14.0% | 0.223% | |
| 2/17/2025 | Redmile Group LLC | 2,895,478 | $38.13M | 2.7% | -9.4% | 4.758% | |
| 2/17/2025 | Polar Asset Management Partners Inc. | 62,600 | $824K | 0.0% | -63.2% | 0.103% | |
| 2/17/2025 | ProShare Advisors LLC | 18,931 | $249K | 0.0% | +31.8% | 0.031% | |
| 2/17/2025 | Paradigm Biocapital Advisors LP | 3,197,050 | $42.11M | 1.5% | +3.0% | 5.254% | |
| 2/17/2025 | Nuveen Asset Management LLC | 206,947 | $2.73M | 0.0% | -38.3% | 0.340% | |
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| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 103,563 | $1.36M | 0.1% | +22.0% | 0.170% | |
| 2/17/2025 | Granahan Investment Management LLC | 527,147 | $6.94M | 0.3% | -28.6% | 0.866% | |
| 2/17/2025 | Deutsche Bank AG | 2,551,865 | $33.61M | 0.0% | +66.3% | 4.194% | |
| 2/17/2025 | Corton Capital Inc. | 10,497 | $138K | 0.1% | N/A | 0.017% | |
| 2/17/2025 | Bank of America Corp DE | 120,977 | $1.59M | 0.0% | -80.7% | 0.199% | |
| 2/17/2025 | BNP Paribas Financial Markets | 7,512 | $99K | 0.0% | N/A | 0.012% | |
| 2/14/2025 | First Light Asset Management LLC | 1,681,110 | $22.14M | 2.1% | -34.7% | 2.763% | |
| 2/14/2025 | Northern Trust Corp | 555,600 | $7.32M | 0.0% | +10.7% | 0.913% | |
| 2/14/2025 | Aquatic Capital Management LLC | 5,596 | $74K | 0.0% | +1,299.0% | 0.009% | |
| 2/14/2025 | Blue Owl Capital Holdings LP | 2,769,199 | $36.47M | 8.6% | -7.8% | 4.551% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 649,660 | $8.56M | 0.0% | N/A | 1.068% | |
| 2/14/2025 | Price T Rowe Associates Inc. MD | 4,634,486 | $61.04M | 0.0% | -4.1% | 7.616% | |
| 2/14/2025 | Silverarc Capital Management LLC | 1,315,601 | $17.33M | 3.8% | N/A | 2.162% | |
| 2/14/2025 | Rock Springs Capital Management LP | 404,796 | $5.33M | 0.2% | +5.1% | 0.665% | |
| 2/14/2025 | MetLife Investment Management LLC | 36,788 | $484K | 0.0% | +11.9% | 0.060% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 547,297 | $7.21M | 0.0% | +20.0% | 0.899% | |
| 2/13/2025 | Marshall Wace LLP | 53,880 | $710K | 0.0% | N/A | 0.089% | |
| 2/13/2025 | Jump Financial LLC | 19,402 | $256K | 0.0% | N/A | 0.032% | |
| 2/13/2025 | Barclays PLC | 101,823 | $1.34M | 0.0% | -75.8% | 0.167% | |
| 2/13/2025 | Fernwood Investment Management LLC | 425,424 | $5.60M | 1.9% | -17.1% | 0.699% | |
| 2/13/2025 | Renaissance Technologies LLC | 27,800 | $366K | 0.0% | -72.5% | 0.046% | |
| 2/13/2025 | Legal & General Group Plc | 52,961 | $697K | 0.0% | +21.5% | 0.087% | |
| 2/13/2025 | ADAR1 Capital Management LLC | 134,798 | $1.78M | 0.4% | -45.2% | 0.222% | |
| 2/13/2025 | Rhenman & Partners Asset Management AB | 116,250 | $1.53M | 0.2% | -3.3% | 0.191% | |
| 2/13/2025 | Wells Fargo & Company MN | 85,880 | $1.13M | 0.0% | -7.9% | 0.141% | |
| 2/12/2025 | ExodusPoint Capital Management LP | 93,804 | $1.24M | 0.0% | -11.1% | 0.154% | |
| 2/12/2025 | Trexquant Investment LP | 62,477 | $823K | 0.0% | -28.1% | 0.103% | |
| 2/12/2025 | Franklin Resources Inc. | 1,045,577 | $13.77M | 0.0% | +0.5% | 1.718% | |
| 2/12/2025 | Pictet Asset Management Holding SA | 1,266,030 | $16.67M | 0.0% | -1.1% | 2.081% | |
| 2/12/2025 | JPMorgan Chase & Co. | 197,251 | $2.60M | 0.0% | +300.8% | 0.324% | |
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| 2/11/2025 | Vanguard Group Inc. | 3,228,755 | $42.52M | 0.0% | -8.4% | 5.306% | |
| 2/11/2025 | KLP Kapitalforvaltning AS | 8,200 | $108K | 0.0% | N/A | 0.013% | |
| 2/11/2025 | American Century Companies Inc. | 100,849 | $1.33M | 0.0% | +10.9% | 0.166% | |
| 2/10/2025 | Swiss National Bank | 95,700 | $1.26M | 0.0% | +1.6% | 0.157% | |
| 2/7/2025 | AlphaQuest LLC | 6,681 | $88K | 0.0% | -73.9% | 0.011% | |
| 2/7/2025 | Candriam S.C.A. | 900,104 | $11.85M | 0.1% | +8.0% | 1.479% | |
| 2/6/2025 | Atria Investments Inc | 11,821 | $156K | 0.0% | +18.1% | 0.019% | |
| 2/6/2025 | Charles Schwab Investment Management Inc. | 459,384 | $6.05M | 0.0% | +0.6% | 0.755% | |
| 1/31/2025 | Rice Hall James & Associates LLC | 160,522 | $2.11M | 0.1% | +2.1% | 0.264% | |
| 1/31/2025 | HighMark Wealth Management LLC | 75,000 | $988K | 0.6% | +11.1% | 0.123% | |
| 1/30/2025 | Rhumbline Advisers | 92,580 | $1.22M | 0.0% | -2.2% | 0.152% | |
| 1/24/2025 | China Universal Asset Management Co. Ltd. | 12,903 | $170K | 0.0% | +10.3% | 0.021% | |
| 1/23/2025 | R Squared Ltd | 2,490 | $33K | 0.0% | N/A | 0.004% | |
| 1/17/2025 | SG Americas Securities LLC | 30,729 | $405K | 0.0% | +27.2% | 0.050% | |
| 1/15/2025 | Hennion & Walsh Asset Management Inc. | 108,608 | $1.43M | 0.1% | +18.1% | 0.178% | |
| 1/10/2025 | Harbor Capital Advisors Inc. | 95,801 | $1.26M | 0.1% | +4.2% | 0.157% | |
| 12/13/2024 | Exome Asset Management LLC | 149,600 | $1.68M | 1.1% | +20.6% | 0.246% | |
| 11/27/2024 | Franklin Resources Inc. | 1,039,904 | $11.66M | 0.0% | +1.5% | 1.709% | |
| 11/16/2024 | Geode Capital Management LLC | 1,318,308 | $14.78M | 0.0% | +2.4% | 2.166% | |
| 11/15/2024 | Y Intercept Hong Kong Ltd | 30,471 | $342K | 0.0% | N/A | 0.050% | |
| 11/15/2024 | Sphera Funds Management LTD. | 297,362 | $3.33M | 0.5% | +15.0% | 0.489% | |
| 11/15/2024 | State Street Corp | 1,402,730 | $15.73M | 0.0% | +1.9% | 2.305% | |
| 11/15/2024 | Redmile Group LLC | 3,197,491 | $35.84M | 2.1% | -0.4% | 5.254% | |
| 11/15/2024 | Polar Asset Management Partners Inc. | 170,200 | $1.91M | 0.0% | +265.2% | 0.280% | |
| 11/15/2024 | Checkpoint Capital L.P. | 380,000 | $4.26M | 2.1% | +63.7% | 0.624% | |
| 11/13/2024 | Great Point Partners LLC | 1,910,121 | $21.41M | 6.3% | -27.6% | 3.139% | |
| 11/13/2024 | FMR LLC | 3,899,481 | $43.71M | 0.0% | -0.3% | 6.408% | |
| 11/13/2024 | The Manufacturers Life Insurance Company | 75,268 | $844K | 0.0% | -9.8% | 0.124% | |
| 11/12/2024 | Algert Global LLC | 106,562 | $1.20M | 0.0% | +52.6% | 0.175% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 456,663 | $5.12M | 0.0% | +4.4% | 0.751% | |
| 11/9/2024 | Intech Investment Management LLC | 12,913 | $145K | 0.0% | N/A | 0.021% | |
| 11/8/2024 | Connor Clark & Lunn Investment Management Ltd. | 34,611 | $388K | 0.0% | N/A | 0.057% | |
| 11/7/2024 | Quest Partners LLC | 25,571 | $287K | 0.0% | -20.5% | 0.042% | |
| 11/1/2024 | Atria Investments Inc | 10,009 | $112K | 0.0% | N/A | 0.016% | |
| 10/29/2024 | Fernwood Investment Management LLC | 513,136 | $5.75M | 1.9% | +3.4% | 0.844% | |
| 10/29/2024 | Harbor Capital Advisors Inc. | 91,979 | $1.03M | 0.0% | +233.8% | 0.151% | |
| 10/28/2024 | Rice Hall James & Associates LLC | 157,217 | $1.76M | 0.1% | +23.2% | 0.259% | |
| 10/25/2024 | China Universal Asset Management Co. Ltd. | 11,694 | $131K | 0.0% | +65.0% | 0.019% | |
| 10/23/2024 | Hennion & Walsh Asset Management Inc. | 91,974 | $1.03M | 0.0% | +34.7% | 0.151% | |
| 10/3/2024 | SG Americas Securities LLC | 24,150 | $271K | 0.0% | -47.4% | 0.040% | |
| 8/16/2024 | Algert Global LLC | 69,842 | $751K | 0.0% | +312.5% | 0.115% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 83,483 | $897K | 0.0% | +1.4% | 0.137% | |
| 8/15/2024 | Deerfield Management Company L.P. Series C | 11,678 | $126K | 0.0% | N/A | 0.019% | |
| 8/14/2024 | Squarepoint Ops LLC | 80,475 | $865K | 0.0% | N/A | 0.132% | |
| 8/14/2024 | First Light Asset Management LLC | 3,401,213 | $36.56M | 3.2% | -3.8% | 5.594% | |
| 8/14/2024 | Great Point Partners LLC | 2,636,864 | $28.35M | 5.4% | +42.4% | 4.337% | |
| 8/14/2024 | ProShare Advisors LLC | 11,379 | $122K | 0.0% | -21.5% | 0.019% | |
| 8/13/2024 | Ensign Peak Advisors Inc | 35,368 | $380K | 0.0% | +39.1% | 0.059% | |
| 8/9/2024 | Renaissance Technologies LLC | 253,369 | $2.72M | 0.0% | +233.8% | 0.420% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 305,322 | $3.28M | 0.0% | +1.7% | 0.506% | |
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| 8/8/2024 | American Century Companies Inc. | 74,113 | $797K | 0.0% | +18.1% | 0.123% | |
| 8/8/2024 | Rice Hall James & Associates LLC | 127,634 | $1.37M | 0.1% | N/A | 0.212% | |
| 8/6/2024 | Quest Partners LLC | 32,175 | $346K | 0.0% | +75.8% | 0.053% | |
| 8/6/2024 | Candriam S.C.A. | 833,216 | $8.96M | 0.1% | +52.0% | 1.381% | |
| 8/1/2024 | Rhumbline Advisers | 96,488 | $1.04M | 0.0% | +17.9% | 0.160% | |
| 7/29/2024 | HighMark Wealth Management LLC | 67,500 | $726K | 0.4% | +58.8% | 0.112% | |
| 7/26/2024 | Summit Securities Group LLC | 5,532 | $59K | 0.0% | N/A | 0.009% | |
| 7/26/2024 | Bank of New York Mellon Corp | 228,693 | $2.46M | 0.0% | +14.9% | 0.379% | |
| 7/20/2024 | Hennion & Walsh Asset Management Inc. | 68,289 | $734K | 0.0% | N/A | 0.113% | |
| 7/12/2024 | SG Americas Securities LLC | 45,891 | $493K | 0.0% | +536.3% | 0.076% | |
