Prothena (PRTA) Competitors $13.01 -0.36 (-2.69%) Closing price 03/27/2025 04:00 PM EasternExtended Trading$13.00 -0.01 (-0.08%) As of 03/27/2025 04:24 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock PRTA vs. MTSR, ACAD, MOR, RXRX, XENE, AMRX, CPRX, HCM, BHC, and NAMSShould you be buying Prothena stock or one of its competitors? The main competitors of Prothena include Metsera (MTSR), ACADIA Pharmaceuticals (ACAD), MorphoSys (MOR), Recursion Pharmaceuticals (RXRX), Xenon Pharmaceuticals (XENE), Amneal Pharmaceuticals (AMRX), Catalyst Pharmaceuticals (CPRX), HUTCHMED (HCM), Bausch Health Companies (BHC), and NewAmsterdam Pharma (NAMS). These companies are all part of the "pharmaceutical products" industry. Prothena vs. Metsera ACADIA Pharmaceuticals MorphoSys Recursion Pharmaceuticals Xenon Pharmaceuticals Amneal Pharmaceuticals Catalyst Pharmaceuticals HUTCHMED Bausch Health Companies NewAmsterdam Pharma Prothena (NASDAQ:PRTA) and Metsera (NASDAQ:MTSR) are both medical companies, but which is the better stock? We will contrast the two businesses based on the strength of their profitability, community ranking, valuation, media sentiment, earnings, analyst recommendations, risk, institutional ownership and dividends. Does the media refer more to PRTA or MTSR? In the previous week, Metsera had 5 more articles in the media than Prothena. MarketBeat recorded 9 mentions for Metsera and 4 mentions for Prothena. Prothena's average media sentiment score of 1.47 beat Metsera's score of 1.01 indicating that Prothena is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Prothena 1 Very Positive mention(s) 1 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Metsera 2 Very Positive mention(s) 1 Positive mention(s) 4 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Does the MarketBeat Community believe in PRTA or MTSR? Prothena received 608 more outperform votes than Metsera when rated by MarketBeat users. However, 100.00% of users gave Metsera an outperform vote while only 70.43% of users gave Prothena an outperform vote. CompanyUnderperformOutperformProthenaOutperform Votes61270.43% Underperform Votes25729.57% MetseraOutperform Votes4100.00% Underperform VotesNo Votes Which has higher valuation & earnings, PRTA or MTSR? Metsera has lower revenue, but higher earnings than Prothena. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioProthena$135.16M5.18-$147.03M-$2.30-5.66MetseraN/AN/AN/AN/AN/A Is PRTA or MTSR more profitable? Metsera has a net margin of 0.00% compared to Prothena's net margin of -90.50%. Metsera's return on equity of 0.00% beat Prothena's return on equity.Company Net Margins Return on Equity Return on Assets Prothena-90.50% -22.67% -19.68% Metsera N/A N/A N/A Do analysts rate PRTA or MTSR? Prothena currently has a consensus target price of $55.00, indicating a potential upside of 322.75%. Metsera has a consensus target price of $47.00, indicating a potential upside of 56.61%. Given Prothena's higher possible upside, analysts plainly believe Prothena is more favorable than Metsera.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Prothena 0 Sell rating(s) 2 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 2.75Metsera 0 Sell rating(s) 0 Hold rating(s) 4 Buy rating(s) 0 Strong Buy rating(s) 3.00 Do institutionals and insiders believe in PRTA or MTSR? 97.1% of Prothena shares are owned by institutional investors. 28.2% of Prothena shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company is poised for long-term growth. SummaryProthena beats Metsera on 7 of the 13 factors compared between the two stocks. Remove Ads Get Prothena News Delivered to You Automatically Sign up to receive the latest news and ratings for PRTA and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart PRTA vs. The Competition Export to ExcelMetricProthenaPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$719.67M$6.91B$5.64B$8.06BDividend YieldN/A2.73%4.57%4.02%P/E Ratio-5.667.2023.1319.03Price / Sales5.18226.01383.8993.17Price / CashN/A65.6738.1634.64Price / Book1.246.476.944.33Net Income-$147.03M$141.90M$3.20B$247.06M7 Day Performance1.09%-3.05%-2.30%-0.52%1 Month Performance-14.01%-4.63%3.10%-3.73%1 Year Performance-48.29%-8.61%11.22%1.74% Prothena Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)PRTAProthena3.3747 of 5 stars$13.01-2.7%$55.00+322.8%-48.3%$719.67M$135.16M-5.66130Analyst RevisionNews CoveragePositive NewsMTSRMetseraN/A$28.38+12.6%$47.00+65.6%N/A$2.92BN/A0.0081Earnings ReportNews CoverageACADACADIA Pharmaceuticals4.1525 of 5 stars$17.20-1.7%$24.00+39.5%-5.5%$2.87B$957.80M22.05510MORMorphoSysN/A$18.96flatN/AN/A$2.86B$238.28M-5.45730RXRXRecursion Pharmaceuticals2.2211 of 5 stars$6.84+7.7%$8.25+20.6%-41.3%$2.75B$58.49M-4.47400Gap DownXENEXenon Pharmaceuticals2.4877 of 5 stars$35.60+0.8%$57.38+61.2%-19.9%$2.72B$9.43M-12.62210AMRXAmneal Pharmaceuticals3.458 of 5 stars$8.62-1.5%$10.80+25.3%+35.1%$2.67B$2.79B-12.687,700Positive NewsCPRXCatalyst Pharmaceuticals4.8399 of 5 stars$21.81+3.8%$32.50+49.0%+52.7%$2.65B$491.73M18.4880HCMHUTCHMED1.6515 of 5 stars$15.14-3.5%$19.00+25.5%-9.4%$2.64B$610.81M0.001,988Gap DownBHCBausch Health Companies3.5511 of 5 stars$7.06-1.3%$7.42+5.1%-35.7%$2.60B$9.63B-58.7920,270Options VolumeNews CoverageNAMSNewAmsterdam Pharma2.1131 of 5 stars$23.34-0.1%$43.33+85.7%-1.3%$2.56B$45.56M-8.984Short Interest ↑High Trading Volume Remove Ads Related Companies and Tools Related Companies Metsera Competitors ACADIA Pharmaceuticals Competitors MorphoSys Competitors Recursion Pharmaceuticals Competitors Xenon Pharmaceuticals Competitors Amneal Pharmaceuticals Competitors Catalyst Pharmaceuticals Competitors HUTCHMED Competitors Bausch Health Companies Competitors NewAmsterdam Pharma Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:PRTA) was last updated on 3/28/2025 by MarketBeat.com Staff From Our PartnersA $6.9 Trillion Cash Tsunami Is Coming – Move Your Money NOWExpert: "Prepare For the Mother of All Melt-Ups" In the wake of Wall Street volatility, stock-picking legen...Stansberry Research | SponsoredElon Warns: Exec Order 14024 Targets DollarExecutive Order 14024 is paving the way for irreversible damage to the dollar's value—threatening your wealth,...Priority Gold | SponsoredWarning: “DOGE Collapse” imminentElon Strikes Back You may already sense that the tide is turning against Elon Musk and DOGE. 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