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Prothena (PRTA) Competitors

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$8.77 +0.21 (+2.45%)
Closing price 08/22/2025 04:00 PM Eastern
Extended Trading
$8.76 -0.01 (-0.17%)
As of 08/22/2025 07:44 PM Eastern
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PRTA vs. DYN, APGE, TWST, TVTX, BHVN, IMCR, CDTX, AUPH, WVE, and JANX

Should you be buying Prothena stock or one of its competitors? The main competitors of Prothena include Dyne Therapeutics (DYN), Apogee Therapeutics (APGE), Twist Bioscience (TWST), Travere Therapeutics (TVTX), Biohaven (BHVN), Immunocore (IMCR), Cidara Therapeutics (CDTX), Aurinia Pharmaceuticals (AUPH), WAVE Life Sciences (WVE), and Janux Therapeutics (JANX). These companies are all part of the "pharmaceutical products" industry.

Prothena vs. Its Competitors

Prothena (NASDAQ:PRTA) and Dyne Therapeutics (NASDAQ:DYN) are both small-cap medical companies, but which is the superior business? We will compare the two companies based on the strength of their media sentiment, valuation, dividends, institutional ownership, analyst recommendations, risk, profitability and earnings.

97.1% of Prothena shares are held by institutional investors. Comparatively, 96.7% of Dyne Therapeutics shares are held by institutional investors. 9.2% of Prothena shares are held by company insiders. Comparatively, 14.1% of Dyne Therapeutics shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

In the previous week, Dyne Therapeutics had 4 more articles in the media than Prothena. MarketBeat recorded 5 mentions for Dyne Therapeutics and 1 mentions for Prothena. Dyne Therapeutics' average media sentiment score of 0.90 beat Prothena's score of 0.56 indicating that Dyne Therapeutics is being referred to more favorably in the news media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Prothena
0 Very Positive mention(s)
0 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Dyne Therapeutics
3 Very Positive mention(s)
0 Positive mention(s)
2 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive

Prothena has higher revenue and earnings than Dyne Therapeutics. Dyne Therapeutics is trading at a lower price-to-earnings ratio than Prothena, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Prothena$10.34M45.65-$122.31M-$5.64-1.55
Dyne TherapeuticsN/AN/A-$317.42M-$3.86-3.26

Prothena presently has a consensus price target of $30.25, indicating a potential upside of 244.93%. Dyne Therapeutics has a consensus price target of $33.80, indicating a potential upside of 168.68%. Given Prothena's higher probable upside, research analysts clearly believe Prothena is more favorable than Dyne Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Prothena
1 Sell rating(s)
4 Hold rating(s)
4 Buy rating(s)
0 Strong Buy rating(s)
2.33
Dyne Therapeutics
0 Sell rating(s)
2 Hold rating(s)
12 Buy rating(s)
2 Strong Buy rating(s)
3.00

Prothena has a beta of -0.03, indicating that its share price is 103% less volatile than the S&P 500. Comparatively, Dyne Therapeutics has a beta of 1.08, indicating that its share price is 8% more volatile than the S&P 500.

Dyne Therapeutics has a net margin of 0.00% compared to Prothena's net margin of -2,929.30%. Prothena's return on equity of -62.17% beat Dyne Therapeutics' return on equity.

Company Net Margins Return on Equity Return on Assets
Prothena-2,929.30% -62.17% -54.43%
Dyne Therapeutics N/A -64.12%-56.75%

Summary

Dyne Therapeutics beats Prothena on 9 of the 16 factors compared between the two stocks.

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New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding PRTA and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
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Media Sentiment Over Time

This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
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PRTA vs. The Competition

MetricProthenaMED IndustryMedical SectorNASDAQ Exchange
Market Cap$472.09M$3.11B$5.81B$9.76B
Dividend YieldN/A2.23%4.39%4.06%
P/E Ratio-1.5521.0031.3626.05
Price / Sales45.65209.44387.8788.42
Price / CashN/A44.5038.0259.36
Price / Book1.458.129.536.60
Net Income-$122.31M-$54.72M$3.26B$265.65M
7 Day Performance6.30%2.62%2.14%2.00%
1 Month Performance30.90%3.25%3.22%0.46%
1 Year Performance-59.60%10.82%30.18%18.88%

Prothena Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
PRTA
Prothena
3.294 of 5 stars
$8.77
+2.5%
$30.25
+244.9%
-59.6%$472.09M$10.34M-1.55130
DYN
Dyne Therapeutics
3.4201 of 5 stars
$12.33
-0.4%
$33.80
+174.1%
-73.0%$1.76BN/A-3.19100
APGE
Apogee Therapeutics
3.5567 of 5 stars
$36.90
-1.0%
$99.00
+168.3%
-20.9%$1.72BN/A-8.9391
TWST
Twist Bioscience
4.1567 of 5 stars
$28.02
-0.4%
$49.40
+76.3%
-34.5%$1.70B$312.97M-19.32990Positive News
TVTX
Travere Therapeutics
2.4123 of 5 stars
$18.77
-0.3%
$32.21
+71.6%
+99.6%$1.68B$233.18M-9.20460News Coverage
Positive News
Analyst Downgrade
BHVN
Biohaven
3.823 of 5 stars
$16.02
+2.0%
$53.75
+235.5%
-62.6%$1.66BN/A-2.09239Trending News
Analyst Forecast
Options Volume
Gap Up
IMCR
Immunocore
1.7738 of 5 stars
$32.31
-1.7%
$58.00
+79.5%
-7.9%$1.66B$310.20M-80.78320Positive News
CDTX
Cidara Therapeutics
3.5423 of 5 stars
$63.24
-3.0%
$64.14
+1.4%
+411.3%$1.65B$1.27M-5.6890
AUPH
Aurinia Pharmaceuticals
2.525 of 5 stars
$12.22
-0.4%
$12.00
-1.8%
+81.5%$1.62B$260.11M28.42300Positive News
WVE
WAVE Life Sciences
4.7597 of 5 stars
$9.74
-0.2%
$20.27
+108.1%
+76.8%$1.55B$108.30M-10.82240Positive News
JANX
Janux Therapeutics
2.1448 of 5 stars
$25.53
+1.7%
$91.89
+259.9%
-47.1%$1.51B$10.59M-14.1830News Coverage

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This page (NASDAQ:PRTA) was last updated on 8/24/2025 by MarketBeat.com Staff
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