Regulus Therapeutics (RGLS) Short Interest Ratio & Short Volume $1.50 +0.21 (+16.28%) Closing price 03/27/2025 04:00 PM EasternExtended Trading$1.56 +0.06 (+4.00%) As of 03/27/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock Regulus Therapeutics Short Interest DataRegulus Therapeutics (RGLS) has a short interest of 2.04 million shares, representing 3.84% of the float (the number of shares available for trading by the public). This marks a -8.93% decrease in short interest from the previous month. The short interest ratio (days to cover) is 4.4, indicating that it would take 4.4 days of the average trading volume of 624,771 shares to cover all short positions.Current Short Interest2,040,000 sharesPrevious Short Interest2,240,000 sharesChange Vs. Previous Month-8.93%Dollar Volume Sold Short$3.02 millionShort Interest Ratio4.4 Days to CoverLast Record DateMarch 15, 2025Outstanding Shares66,243,000 sharesFloat Size53,180,000 sharesShort Percent of Float3.84%Today's Trading Volume32,466,760 sharesAverage Trading Volume624,771 sharesToday's Volume Vs. Average5,197% Short Selling Regulus Therapeutics? Sign up to receive the latest short interest report for Regulus Therapeutics and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartRGLS Short Interest Over TimeRGLS Days to Cover Over TimeRGLS Percentage of Float Shorted Over Time Remove Ads Regulus Therapeutics Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 3/15/20252,040,000 shares $3.02 million -8.9%3.8%4.4 $1.48 2/28/20252,240,000 shares $3.02 million +10.3%4.3%5.1 $1.35 2/15/20252,030,000 shares $2.46 million +3.6%3.9%4.5 $1.21 1/31/20251,960,000 shares $1.96 million +11.4%3.7%4.1 $1.00 1/15/20251,760,000 shares $2.24 million +3.5%3.3%5 $1.27 12/31/20241,700,000 shares $2.69 million +4.9%3.2%5.1 $1.58 12/15/20241,620,000 shares $2.56 million +15.7%3.1%4.9 $1.58 11/30/20241,400,000 shares $2.25 million -14.6%2.7%4 $1.61 11/15/20241,640,000 shares $2.35 million -3.0%3.1%4.6 $1.43 10/31/20241,690,000 shares $2.47 million -32.4%3.2%4.7 $1.46 Get the Latest News and Ratings for RGLS and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Regulus Therapeutics and its competitors with MarketBeat's FREE daily newsletter. 10/15/20242,500,000 shares $3.75 million -12.3%4.7%7.3 $1.50 9/30/20242,850,000 shares $4.47 million -13.4%5.4%7.7 $1.57 9/15/20243,290,000 shares $5.30 million -1.2%6.2%4.6 $1.61 8/31/20243,330,000 shares $5.59 million -7.0%6.3%4.2 $1.68 8/15/20243,580,000 shares $5.69 million -8.7%6.8%4.4 $1.59 7/31/20243,920,000 shares $7.06 million -9.7%7.4%4.6 $1.80 7/15/20244,340,000 shares $7.55 million -18.1%8.2%5.3 $1.74 6/30/20245,300,000 shares $9.46 million +48.0%10.0%6.6 $1.79 6/15/20243,580,000 shares $8.63 million +38.2%6.8%5.1 $2.41 5/31/20242,590,000 shares $5.93 million -10.1%4.9%0.8 $2.29 5/15/20242,880,000 shares $5.82 million -31.6%5.4%0.9 $2.02 4/30/20244,210,000 shares $9.68 million -32.9%7.3%1.4 $2.30 4/15/20246,270,000 shares $17.43 million +15.7%10.9%2.1 $2.78 3/31/20245,420,000 shares $15.61 million +5.7%9.4%1.8 $2.88 3/15/20245,130,000 shares $10.82 million +9,244.3%13.0%1.8 $2.11 2/29/202454,900 shares $80,703.00 -43.4%0.3%1.4 $1.47 2/15/202497,000 shares $143,560.00 -16.6%0.6%2.6 $1.48 1/31/2024116,300 shares $147,701.00 -7.3%0.7%4.4 $1.27 1/15/2024125,500 shares $163,150.00 -9.3%0.7%5.1 $1.30 12/31/2023138,400 shares $177,152.00 -6.6%0.8%6.9 $1.28 12/15/2023148,100 shares $202,897.00 -0.1%0.9%7.6 $1.37 11/30/2023148,200 shares $194,142.00 -18.3%0.9%4.4 $1.31 11/15/2023181,300 shares $252,007.00 -5.2%1.0%4.9 $1.39 10/31/2023191,200 shares $231,352.00 -0.7%1.1%5.4 $1.21 10/15/2023192,600 shares $242,676.00 -1.0%1.2%5.5 $1.26 9/30/2023194,500 shares $266,465.00 -0.2%1.2%5.6 $1.37 9/15/2023194,800 shares $331,160.00 +4.2%1.2%5.6 $1.70 8/31/2023187,000 shares $291,720.00 -10.2%1.1%5.7 $1.56 8/15/2023208,300 shares $281,205.00 -3.7%1.3%9.6 $1.35 7/31/2023216,300 shares $302,820.00 -3.9%1.3%7.8 $1.40A $6.9 Trillion Cash Tsunami Is Coming – Move Your Money NOW (Ad)Expert: "Prepare For the Mother of All Melt-Ups" In the wake of Wall Street volatility, stock-picking legend (with 255 winners to his name) has just predicted a dramatic - and completely unexpected - stock market rebound... as a $6.9 trillion cash tsunami floods back into stocks. He just shared the name of one stock which could potentially surge 300% or higher, free of charge.While it's online, get the facts - and his #1 stock right here. 7/15/2023225,000 shares $328,500.00 -2.5%1.4%7.7 $1.46 6/30/2023230,700 shares $339,129.00 +6.5%1.4%4.1 $1.47 6/15/2023216,700 shares $312,048.00 +3.0%1.3%3.4 $1.44 5/31/2023210,300 shares $273,390.00 -17.1%1.3%3.1 $1.30 5/15/2023253,700 shares $393,235.00 +26.0%1.6%3.8 $1.55 4/30/2023201,300 shares $268,735.50 +18.1%1.4%3.4 $1.34 4/15/2023170,500 shares $202,895.00 -13.9%1.2%2.6 $1.19 3/31/2023198,000 shares $167,805.00 +11.1%1.3%4.8 $0.85 3/15/2023178,200 shares $215,622.00 -3.7%1.2%4 $1.21 2/28/2023185,100 shares $248,034.00 -1.9%1.3%4.1 $1.34 2/15/2023188,600 shares $262,154.00 -6.8%1.3%4.2 $1.39 1/31/2023202,400 shares $291,456.00 -3.2%1.4%4.3 $1.44 1/15/2023209,000 shares $311,410.00 +0.8%1.4%4.7 $1.49 12/30/2022207,400 shares $284,138.00 -10.8%1.4%4.7 $1.37 12/15/2022232,600 shares $327,966.00 -16.2%1.6%5.4 $1.41 11/30/2022277,500 shares $474,525.00 -2.6%1.9%0.3 $1.71 11/15/2022284,900 shares $490,028.00 +5.1%2.0%0.3 $1.72 10/31/2022271,100 shares $420,205.00 -1.7%N/A0.3 $1.55 10/15/2022275,900 shares $449,717.00 -7.4%N/A0.3 $1.63 9/30/2022297,900 shares $506,430.00 -49.9%N/A0.3 $1.70 9/15/2022594,600 shares $1.24 million +98.7%N/A0.7 $2.09 8/31/2022299,300 shares $425,006.00 -15.2%N/A0.4 $1.42 8/15/2022353,000 shares $638,930.00 +56.1%N/A3 $1.81 7/31/2022226,200 shares $364,182.00 -7.1%N/A1 $1.61 7/15/2022243,500 shares $560,050.00 +1.4%N/A1.2 $2.30 6/30/2022240,100 shares $497,007.00 -91.3%N/A1.2 $2.07 6/15/20222,770,000 shares $678,927.00 -9.2%N/A1.4 $0.25 5/31/20223,050,000 shares $873,825.00 -30.8%N/A1.5 $0.29 5/15/20224,410,000 shares $948,150.00 +53.1%N/A2 $0.22 4/30/20222,880,000 shares $581,760.00 -10.8%N/A2.7 $0.20 4/15/20223,230,000 shares $823,650.00 -2.4%N/A2.8 $0.26 3/31/20223,310,000 shares $986,380.00 +1.5%N/A2.3 $0.30 3/15/20223,260,000 shares $867,160.00 +21.2%N/A2.3 $0.27 2/28/20222,690,000 shares $605,250.00 -17.5%N/A1.9 $0.23 2/15/20223,260,000 shares $815,326.00 +4.5%N/A2.5 $0.25 1/31/20223,120,000 shares $769,704.00 +24.8%4.2%2.2 $0.25 1/15/20222,500,000 shares $617,500.00 -8.8%3.3%1.5 $0.25 12/31/20212,740,000 shares $863,100.00 -18.7%4.1%1.3 $0.32 12/15/20213,370,000 shares $1.18 million -0.6%5.1%1.6 $0.35 11/30/20213,390,000 shares $1.31 million -19.7%4.5%1.7 $0.39 11/15/20214,220,000 shares $1.76 million -4.5%N/A2.1 $0.42 10/29/20214,420,000 shares $2.04 million -8.3%N/A2.3 $0.46 10/15/20214,820,000 shares $2.34 million -8.5%N/A2.9 $0.49 9/30/20215,270,000 shares $3.64 million +6.0%N/A6.5 $0.69 9/15/20214,970,000 shares $3.48 million +0.4%N/A4 $0.70 8/31/20214,950,000 shares $3.84 million -5.9%N/A1.7 $0.78 8/13/20215,260,000 shares $3.53 million -0.8%N/A1.7 $0.67 7/30/20215,300,000 shares $3.71 million -12.3%8.2%1.7 $0.70 7/15/20216,040,000 shares $4.35 million -2.6%9.3%1.9 $0.72 6/30/20216,200,000 shares $5.04 million +4.7%9.6%1.9 $0.81A $6.9 Trillion Cash Tsunami Is Coming – Move Your Money NOW (Ad)Expert: "Prepare For the Mother of All Melt-Ups" In the wake of Wall Street volatility, stock-picking legend (with 255 winners to his name) has just predicted a dramatic - and completely unexpected - stock market rebound... as a $6.9 trillion cash tsunami floods back into stocks. He just shared the name of one stock which could potentially surge 300% or higher, free of charge.While it's online, get the facts - and his #1 stock right here. 6/15/20215,920,000 shares $5.52 million +0.2%9.1%2 $0.93 5/28/20215,910,000 shares $5.83 million No Change9.1%1.6 $0.99 5/14/20215,910,000 shares $4.85 million -5.4%N/A2.1 $0.82 4/30/20216,250,000 shares $9.19 million -3.0%N/A2.1 $1.47 4/15/20216,440,000 shares $8.76 million -3.5%N/A2 $1.36 3/31/20216,670,000 shares $10.41 million +31.3%N/A2.1 $1.56 3/15/20215,080,000 shares $9.96 million +61.8%N/A1.5 $1.96 2/26/20213,140,000 shares $4.11 million +13.8%N/A1.2 $1.31 2/12/20212,760,000 shares $4.50 million +16.0%N/A1.1 $1.63 1/29/20212,380,000 shares $3.33 million +31.5%N/A1.1 $1.40 1/15/20211,810,000 shares $2.15 million +24.0%N/A0.9 $1.19 12/31/20201,460,000 shares $1.88 million +35.2%N/A0.9 $1.29 12/15/20201,080,000 shares $1.24 million +54.8%N/A0.7 $1.15 11/30/2020697,800 shares $444,289.26 -30.0%N/A0.9 $0.64 11/15/2020997,100 shares $518,492.00 +7.0%N/A2.1 $0.52 10/30/2020932,300 shares $444,520.64 +12.9%N/A1.8 $0.48 10/15/2020826,100 shares $450,637.55 -6.8%N/A0.6 $0.55 9/30/2020885,900 shares $455,352.60 -19.5%N/A0.5 $0.51 9/15/20201,100,000 shares $611,600.00 -4.4%N/A0.5 $0.56 8/31/20201,150,000 shares $609,500.00 -27.7%N/A0.4 $0.53 8/14/20201,590,000 shares $969,900.00 -3.6%N/A0.6 $0.61 7/31/20201,650,000 shares $1.16 million +131.2%N/A0.6 $0.70 7/15/2020713,800 shares $548,269.78 +189.8%N/A0.4 $0.77 6/30/2020246,300 shares $176,104.50 -65.8%N/A0.2 $0.72 6/15/2020720,200 shares $677,060.02 +25.6%N/A0.6 $0.94 5/29/2020573,600 shares $430,200.00 -15.9%N/A1 $0.75 5/15/2020681,900 shares $408,458.10 +17.9%N/A2.1 $0.60 4/30/2020578,500 shares $296,770.50 +3.9%N/A2.1 $0.51 4/15/2020556,600 shares $263,438.78 +2.8%3.5%2.7 $0.47 3/31/2020541,500 shares $254,505.00 -2.7%3.4%3 $0.47 RGLS Short Interest - Frequently Asked Questions What is Regulus Therapeutics' current short interest? Short interest is the volume of Regulus Therapeutics shares that have been sold short but have not yet been covered or closed out. As of March 15th, traders have sold 2,040,000 shares of RGLS short. 3.84% of Regulus Therapeutics' shares are currently sold short. Learn More on Regulus Therapeutics' current short interest. What is a good short interest ratio for Regulus Therapeutics? The short interest ratio, also known as the "days to cover ratio", is calculated by dividing the number of shares of a stock sold short divided by its average trading volume. A short interest ratio ranging between 1 and 4 generally indicates strong positive sentiment about a stock and a lack of short sellers. A short interest ratio of 10 or greater indicates strong pessimism about a stock. RGLS shares currently have a short interest ratio of 4.0. Learn More on Regulus Therapeutics's short interest ratio. Which institutional investors are shorting Regulus Therapeutics? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Regulus Therapeutics: Citadel Advisors LLC, and Concourse Financial Group Securities Inc.. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Regulus Therapeutics? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 3.84% of Regulus Therapeutics' floating shares are currently sold short. Is Regulus Therapeutics' short interest increasing or decreasing? Regulus Therapeutics saw a drop in short interest in March. As of March 15th, there was short interest totaling 2,040,000 shares, a drop of 8.9% from the previous total of 2,240,000 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. What is Regulus Therapeutics' float size? Regulus Therapeutics currently has issued a total of 66,243,000 shares. Some of Regulus Therapeutics' outstanding shares are available for trading, while others are subject to various restrictions. The public float, also referred to as floating shares or "the float", are shares that publicly owned, unrestricted and available to trade on the open market. Regulus Therapeutics currently has a public float of 53,180,000 shares. How does Regulus Therapeutics' short interest compare to its competitors? 3.84% of Regulus Therapeutics' shares are currently sold short. Here is how the short interest of companies in the industry of "biotechnology" compare to Regulus Therapeutics: Rigel Pharmaceuticals, Inc. (9.03%), Emergent BioSolutions Inc. (17.51%), Verastem, Inc. (16.02%), Vanda Pharmaceuticals Inc. (6.55%), Codexis, Inc. (5.74%), XOMA Co. (1.47%), Ironwood Pharmaceuticals, Inc. (10.47%), Sangamo Therapeutics, Inc. (14.26%), Achieve Life Sciences, Inc. (8.99%), Lexicon Pharmaceuticals, Inc. (17.11%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: Invesco QQQ ($26.28 billion), iShares 20+ Year Treasury Bond ETF ($9.53 billion), MicroStrategy Incorporated ($8.50 billion), Apollo Global Management, Inc. ($4.86 billion), Super Micro Computer, Inc. ($4.85 billion), Charter Communications, Inc. ($4.28 billion), Capital One Financial Co. ($4.08 billion), AppLovin Co. ($3.82 billion), Canadian Natural Resources Limited ($3.78 billion), and Schlumberger Limited ($2.87 billion). View all of the most shorted stocks. What does it mean to sell short Regulus Therapeutics stock? Short selling RGLS is an investing strategy that aims to generate trading profit from Regulus Therapeutics as its price is falling. RGLS shares are trading up $0.21 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Regulus Therapeutics? A short squeeze for Regulus Therapeutics occurs when it has a large amount of short interest and its stock increases in price. This forces short sellers to cover their short interest positions by buying actual shares of RGLS, which in turn drives the price of the stock up even further. How often is Regulus Therapeutics' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including RGLS, twice per month. The most recent reporting period available is March, 15 2025. More Short Interest Resources from MarketBeat Related Companies Rigel Pharmaceuticals Short Interest Emergent BioSolutions Short Interest Verastem Short Interest Vanda Pharmaceuticals Short Interest Codexis Short Interest XOMA Short Interest Ironwood Pharmaceuticals Short Interest Sangamo Therapeutics Short Interest Achieve Life Sciences Short Interest Lexicon Pharmaceuticals Short Interest Short Interest Tools Stocks to Short Largest Short Interest Positions Short Interest Increases Short Interest Decreases Short Interest Reporting Dates This page (NASDAQ:RGLS) was last updated on 3/28/2025 by MarketBeat.com Staff From Our PartnersA $6.9 Trillion Cash Tsunami Is Coming – Move Your Money NOWExpert: "Prepare For the Mother of All Melt-Ups" In the wake of Wall Street volatility, stock-picking legen...Stansberry Research | SponsoredElon Warns: Exec Order 14024 Targets DollarExecutive Order 14024 is paving the way for irreversible damage to the dollar's value—threatening your wealth,...Priority Gold | SponsoredWarning: “DOGE Collapse” imminentElon Strikes Back You may already sense that the tide is turning against Elon Musk and DOGE. 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