REGENXBIO (RGNX) Stock Price, News & Analysis

Company Overview

REGENXBIO Inc. is a clinical‐stage biotechnology company specializing in the development of gene therapies using its proprietary NAV® AAV (adeno‐associated virus) platform. The company engineers next‐generation AAV vectors designed to deliver functional genes to targeted cells, aiming to address a range of rare genetic diseases and ocular, metabolic and neurologic disorders. REGENXBIO’s pipeline features several product candidates in various stages of preclinical and clinical development, including RGX-314 for wet age‐related macular degeneration, RGX-121 for mucopolysaccharidosis II (Hunter syndrome) and RGX-121 for other rare lysosomal storage diseases.

In addition to its internally funded programs, REGENXBIO has established partnerships with major biopharmaceutical companies to advance its NAV technology. These collaborations leverage the company’s vector engineering expertise to create bespoke gene therapies across multiple therapeutic areas. Through such alliances, REGENXBIO gains access to complementary development resources, while partners benefit from its deep knowledge of AAV vector design and scalable manufacturing processes.

Founded in 2012 and headquartered in Rockville, Maryland, REGENXBIO operates a state‐of‐the‐art manufacturing facility to support both clinical and commercial production of AAV vectors. The company’s leadership team comprises industry veterans with extensive experience in gene therapy research, development and regulatory affairs. REGENXBIO’s scientific advisory board includes academic and clinical experts who guide vector selection, preclinical study design and clinical trial strategy.

REGENXBIO continues to expand its global footprint through clinical trial sites in North America, Europe and Asia, reflecting its commitment to bringing novel gene therapies to patients worldwide. By harnessing the NAV AAV platform’s versatility and safety profile, the company seeks to deliver one‐time treatments that have the potential to transform care for individuals living with severe genetic and ocular diseases.

Key Stats

• Today's Range: $9.56 to $9.97
• 50-Day Range: $7.46 to $9.86
• 52-Week Range: $5.03 to $13.48
• Volume: 609,824 shs
• Average Volume: 643,702 shs
• Market Capitalization: $490.49 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $28.38
• Consensus Rating: Moderate Buy

REGENXBIO Stock Analysis - MarketRank™

REGENXBIO scored higher than 92% of companies evaluated by MarketBeat, and ranked 95th out of 932 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 4.2 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

REGENXBIO has received a consensus rating of Moderate Buy. The company's average rating score is 2.83, and is based on 5 buy ratings, 1 hold rating, and no sell ratings.

Upside Potential

REGENXBIO has a consensus price target of $28.38, representing about 192.2% upside from its current price of $9.71.

Amount of Analyst Coverage

REGENXBIO has only been the subject of 4 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for REGENXBIO are expected to grow in the coming year, from ($4.84) to ($1.25) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of REGENXBIO is -2.82, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of REGENXBIO is -2.82, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

REGENXBIO has a P/B Ratio of 1.85. P/B Ratios below 3 indicates that a company is reasonably valued with respect to its assets and liabilities.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

10.83% of the outstanding shares of REGENXBIO have been sold short.

Short Interest Ratio / Days to Cover

REGENXBIO has a short interest ratio ("days to cover") of 6.6.

Change versus previous month

Short interest in REGENXBIO has recently decreased by 0.18%, indicating that investor sentiment is improving.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

REGENXBIO does not currently pay a dividend.

Dividend Growth

REGENXBIO does not have a long track record of dividend growth.

Sustainability and ESG

• Score: 4.6 / 5
• Environmental Score: -0.82

Percentage of Shares Shorted

10.83% of the outstanding shares of REGENXBIO have been sold short.

Short Interest Ratio / Days to Cover

REGENXBIO has a short interest ratio ("days to cover") of 6.6.

Change versus previous month

Short interest in REGENXBIO has recently decreased by 0.18%, indicating that investor sentiment is improving.

News and Social Media

• Score: 4.2 / 5
• News Sentiment: 1.56

News Sentiment

REGENXBIO has a news sentiment score of 1.56. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.72 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 11 news articles for REGENXBIO this week, compared to 5 articles on an average week.

Search Interest

6 people have searched for RGNX on MarketBeat in the last 30 days. This is an increase of 100% compared to the previous 30 days.

MarketBeat Follows

2 people have added REGENXBIO to their MarketBeat watchlist in the last 30 days.

Company Ownership

• Score: 2.5 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, REGENXBIO insiders have not sold or bought any company stock.

Percentage Held by Insiders

12.79% of the stock of REGENXBIO is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

88.08% of the stock of REGENXBIO is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

RGNX Stock Analysis - Frequently Asked Questions

How have RGNX shares performed this year?

REGENXBIO's stock was trading at $7.73 at the start of the year. Since then, RGNX shares have increased by 25.6% and is now trading at $9.71.

How were REGENXBIO's earnings last quarter?

REGENXBIO Inc. (NASDAQ:RGNX) announced its quarterly earnings results on Thursday, August, 7th. The biotechnology company reported ($1.38) EPS for the quarter, missing analysts' consensus estimates of ($1.13) by $0.25. The biotechnology company earned $21.36 million during the quarter, compared to analysts' expectations of $40.87 million. REGENXBIO had a negative net margin of 112.70% and a negative trailing twelve-month return on equity of 66.95%.
Read the conference call transcript.

Who are REGENXBIO's major shareholders?

REGENXBIO's top institutional investors include Redmile Group LLC (9.45%), JPMorgan Chase & Co. (7.63%), Geode Capital Management LLC (2.25%) and AQR Capital Management LLC (1.84%). Insiders that own company stock include Kenneth T Mills, Kenneth T Mills, Curran Simpson, Steve Pakola and Argeris N Karabelas.
View institutional ownership trends.

How do I buy shares of REGENXBIO?

Shares of RGNX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of REGENXBIO own?

Based on aggregate information from My MarketBeat watchlists, some other companies that REGENXBIO investors own include Voyager Therapeutics (VYGR), American Water Works (AWK), Waste Connections (WCN), The RMR Group (RMR), DiamondRock Hospitality (DRH), AU Optronics (AUOTY) and Humana (HUM).

Company Calendar

• Last Earnings: 8/07/2025
• Today: 9/06/2025
• Next Earnings (Estimated): 11/05/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:RGNX
• CIK: 1590877
• Web: www.regenxbio.com
• Phone: (240) 552-8181
• Fax: N/A
• Employees: 370
• Year Founded: 2009

Price Target and Rating

• Average Price Target for REGENXBIO: $28.38
• High Price Target: $52.00
• Low Price Target: $12.00
• Potential Upside/Downside: +192.2%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.83
• Research Coverage: 6 Analysts

Profitability

• EPS (Trailing Twelve Months): ($3.44)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$227.10 million
• Net Margins: -112.70%
• Pretax Margin: -112.70%
• Return on Equity: -66.95%
• Return on Assets: -34.14%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 3.13
• Quick Ratio: 3.13

Sales & Book Value

• Annual Sales: $155.78 million
• Price / Sales: 3.15
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $5.24 per share
• Price / Book: 1.85

Miscellaneous

• Outstanding Shares: 50,514,000
• Free Float: 44,053,000
• Market Cap: $490.49 million
• Optionable: Optionable
• Beta: 1.17