Shuttle Pharmaceuticals (SHPH) Stock Price, News & Analysis

Company Overview

Shuttle Pharmaceuticals Holdings, Inc., a clinical stage pharmaceutical company, develops novel therapies to cure cancers. It develops Ropidoxuridine, an oral halogenated pyrimidine to treat patients with brain tumors and sarcomas SP-1-161, an HDAC inhibitor that initiates the mutated in ataxia-telangiectasia response pathway for radiation sensitizing cancer cells and protecting normal cells; SP-2-225, a pre-clinical class IIb that effects on the regulation of the immune system; and SP-1-303, a pre-clinical selective Class I HDAC for the treatment of ER positive cancers . The company is based in Gaithersburg, Maryland.

Key Stats

• Today's Range: $0.68 to $0.76
• 50-Day Range: $0.54 to $1.09
• 52-Week Range: $0.50 to $11.25
• Volume: 547,027 shs
• Average Volume: 2.31 million shs
• Market Capitalization: $3.95 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: N/A
• Consensus Rating: Sell

Shuttle Pharmaceuticals Stock Analysis - MarketRank™

Shuttle Pharmaceuticals scored higher than 22% of companies evaluated by MarketBeat. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 0.7 / 5
• Analyst Rating: Sell

Consensus Rating

Shuttle Pharmaceuticals has received a consensus rating of Sell. The company's average rating score is 1.00, and is based on no strong buy ratings, no buy ratings, no hold ratings, and 1 sell rating.

Amount of Analyst Coverage

Shuttle Pharmaceuticals has only been the subject of 1 research reports in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: N/A

Price to Earnings Ratio vs. the Market

The P/E ratio of Shuttle Pharmaceuticals is -0.06, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Shuttle Pharmaceuticals is -0.06, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Book Value per Share Ratio

Shuttle Pharmaceuticals has a P/B Ratio of 0.64. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities.

Short Interest

• Score: 5.0 / 5
• Short Interest Level: Healthy

Percentage of Shares Shorted

1.46% of the float of Shuttle Pharmaceuticals has been sold short.

Short Interest Ratio / Days to Cover

Shuttle Pharmaceuticals has a short interest ratio ("days to cover") of 0.46, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Shuttle Pharmaceuticals has recently decreased by 38.56%, indicating that investor sentiment is improving significantly.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Shuttle Pharmaceuticals does not currently pay a dividend.

Dividend Growth

Shuttle Pharmaceuticals does not have a long track record of dividend growth.

News and Social Media

• Score: 3.2 / 5
• News Sentiment: 0.14

News Sentiment

Shuttle Pharmaceuticals has a news sentiment score of 0.14. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.46 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 3 news articles for Shuttle Pharmaceuticals this week, compared to 1 article on an average week.

Search Interest

2 people have searched for SHPH on MarketBeat in the last 30 days.

MarketBeat Follows

1 people have added Shuttle Pharmaceuticals to their MarketBeat watchlist in the last 30 days.

Company Ownership

• Score: 0.5 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Shuttle Pharmaceuticals insiders have not sold or bought any company stock.

Percentage Held by Insiders

12.60% of the stock of Shuttle Pharmaceuticals is held by insiders. A high percentage of insider ownership can be a sign of company health.

Percentage Held by Institutions

4.58% of the stock of Shuttle Pharmaceuticals is held by institutions.

SHPH Stock Analysis - Frequently Asked Questions

How have SHPH shares performed this year?

Shuttle Pharmaceuticals' stock was trading at $1.80 at the beginning of the year. Since then, SHPH stock has decreased by 60.8% and is now trading at $0.7059.

How were Shuttle Pharmaceuticals' earnings last quarter?

Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ:SHPH) announced its quarterly earnings results on Tuesday, March, 31st. The company reported $0.06 EPS for the quarter.

When did Shuttle Pharmaceuticals' stock split?

Shuttle Pharmaceuticals's stock reverse split on Monday, June 16th 2025.The 1-25 reverse split was announced on Thursday, June 12th 2025. The number of shares owned by shareholders was adjusted after the closing bell on Friday, June 13th 2025. An investor that had 100 shares of stock prior to the reverse split would have 4 shares after the split.

When did Shuttle Pharmaceuticals IPO?

Shuttle Pharmaceuticals (SHPH) raised $10 million in an initial public offering on Tuesday, August 30th 2022. The company issued 1,225,888 shares at a price of $8.13 per share.

How do I buy shares of Shuttle Pharmaceuticals?

Shares of SHPH stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Shuttle Pharmaceuticals own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Shuttle Pharmaceuticals investors own include MSP Recovery (LIFW), NIO (NIO), Tesla (TSLA), Broadcom (AVGO), AMTD Digital (HKD) and NVIDIA (NVDA).

Company Calendar

• Last Earnings: 3/31/2026
• Today: 5/07/2026
• Fiscal Year End: 12/31/2026

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - DRUGS
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:SHPH
• CIK: 1757499
• Web: www.shuttlepharma.com
• Phone: 240-403-4212
• Fax: N/A
• Employees: 5
• Year Founded: 2012

Profitability

• EPS (Trailing Twelve Months): ($11.84)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$11.72 million
• Net Margins: N/A
• Pretax Margin: N/A
• Return on Equity: -444.90%
• Return on Assets: -188.81%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 0.06
• Quick Ratio: 0.06

Sales & Book Value

• Annual Sales: N/A
• Price / Sales: N/A
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: $1.11 per share
• Price / Book: 0.64

Miscellaneous

• Outstanding Shares: 5,590,000
• Free Float: 4,887,000
• Market Cap: $3.95 million
• Optionable: Not Optionable
• Beta: 0.38