Shuttle Pharmaceuticals (SHPH) Competitors $3.30 -0.02 (-0.60%) Closing price 08/29/2025 03:55 PM EasternExtended Trading$3.33 +0.03 (+0.91%) As of 08/29/2025 06:32 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock SHPH vs. PRPH, NXTC, SNGX, APM, TXMD, MRKR, FLGC, HCWB, ALVR, and BFRGShould you be buying Shuttle Pharmaceuticals stock or one of its competitors? The main competitors of Shuttle Pharmaceuticals include ProPhase Labs (PRPH), NextCure (NXTC), Soligenix (SNGX), Aptorum Group (APM), TherapeuticsMD (TXMD), Marker Therapeutics (MRKR), Flora Growth (FLGC), HCW Biologics (HCWB), AlloVir (ALVR), and Bullfrog AI (BFRG). These companies are all part of the "pharmaceutical products" industry. Shuttle Pharmaceuticals vs. Its Competitors ProPhase Labs NextCure Soligenix Aptorum Group TherapeuticsMD Marker Therapeutics Flora Growth HCW Biologics AlloVir Bullfrog AI ProPhase Labs (NASDAQ:PRPH) and Shuttle Pharmaceuticals (NASDAQ:SHPH) are both small-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their dividends, risk, institutional ownership, media sentiment, earnings, analyst recommendations, valuation and profitability. Which has more volatility & risk, PRPH or SHPH? ProPhase Labs has a beta of -0.78, meaning that its share price is 178% less volatile than the S&P 500. Comparatively, Shuttle Pharmaceuticals has a beta of -1.08, meaning that its share price is 208% less volatile than the S&P 500. Is PRPH or SHPH more profitable? ProPhase Labs' return on equity of -262.42% beat Shuttle Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets ProPhase LabsN/A -262.42% -76.48% Shuttle Pharmaceuticals N/A -772.76%-347.06% Which has higher valuation and earnings, PRPH or SHPH? Shuttle Pharmaceuticals has lower revenue, but higher earnings than ProPhase Labs. Shuttle Pharmaceuticals is trading at a lower price-to-earnings ratio than ProPhase Labs, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioProPhase Labs$6.77M2.07-$53.36M-$1.26-0.27Shuttle PharmaceuticalsN/AN/A-$9.15M-$4.15-0.80 Do institutionals & insiders believe in PRPH or SHPH? 9.5% of ProPhase Labs shares are held by institutional investors. Comparatively, 4.6% of Shuttle Pharmaceuticals shares are held by institutional investors. 9.6% of ProPhase Labs shares are held by company insiders. Comparatively, 12.6% of Shuttle Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a stock is poised for long-term growth. Does the media prefer PRPH or SHPH? In the previous week, ProPhase Labs and ProPhase Labs both had 1 articles in the media. Shuttle Pharmaceuticals' average media sentiment score of 1.88 beat ProPhase Labs' score of 1.87 indicating that Shuttle Pharmaceuticals is being referred to more favorably in the news media. Company Overall Sentiment ProPhase Labs Very Positive Shuttle Pharmaceuticals Very Positive SummaryProPhase Labs beats Shuttle Pharmaceuticals on 7 of the 10 factors compared between the two stocks. Get Shuttle Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for SHPH and its competitors with MarketBeat's FREE daily newsletter. 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Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SHPH vs. The Competition Export to ExcelMetricShuttle PharmaceuticalsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$3.53M$2.49B$5.69B$9.74BDividend YieldN/A48.55%6.64%4.48%P/E Ratio-0.8022.8083.1926.59Price / SalesN/A544.56515.16159.07Price / CashN/A26.3325.6628.92Price / Book0.765.3711.766.08Net Income-$9.15M$32.95M$3.27B$265.93M7 Day Performance-0.60%-0.65%1.13%0.36%1 Month Performance-5.71%6.46%8.30%5.58%1 Year Performance-93.16%-3.15%62.26%19.67% Shuttle Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SHPHShuttle Pharmaceuticals1.4313 of 5 stars$3.30-0.6%N/A-93.2%$3.53MN/A-0.805Upcoming EarningsPRPHProPhase Labs1.3355 of 5 stars$0.34+2.3%N/A-87.4%$14.26M$6.77M-0.27130Positive NewsGap DownNXTCNextCure4.3643 of 5 stars$5.22flat$25.50+388.5%-71.5%$13.97MN/A-0.2090Positive NewsSNGXSoligenix2.2733 of 5 stars$3.14+0.3%$6.00+91.1%-11.4%$13.47M$120K-0.8320Positive NewsAPMAptorum Group1.0954 of 5 stars$2.50+7.3%N/A-34.1%$13.37MN/A0.0030Positive NewsTXMDTherapeuticsMD0.5921 of 5 stars$1.12+1.0%N/A-41.1%$12.97M$1.76M0.00420MRKRMarker Therapeutics3.6206 of 5 stars$1.00-20.6%$13.17+1,216.7%-74.4%$12.94M$6.59M-0.7360Gap UpHigh Trading VolumeFLGCFlora Growth3.2364 of 5 stars$21.88+6.0%$93.00+325.0%-48.3%$12.67M$52.37M-0.64280Positive NewsGap UpHCWBHCW Biologics2.4446 of 5 stars$5.89+6.1%$35.00+494.2%-69.0%$12.66M$2.57M-0.4240ALVRAlloVirN/A$2.51flatN/A-77.2%$12.66MN/A-0.12110News CoverageBFRGBullfrog AI0.7804 of 5 stars$1.25+1.6%N/A-53.1%$12.60M$60K-1.644 Related Companies and Tools Related Companies PRPH Alternatives NXTC Alternatives SNGX Alternatives APM Alternatives TXMD Alternatives MRKR Alternatives FLGC Alternatives HCWB Alternatives ALVR Alternatives BFRG Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SHPH) was last updated on 9/1/2025 by MarketBeat.com Staff From Our PartnersRetire Comfortably with These New Monthly Income ETFs?Too many retirees lie awake at night, worried their savings won’t last. 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