Siga Technologies, Inc. (NASDAQ: SIGA) is a specialty pharmaceutical company focused on the development, manufacturing and commercialization of medical countermeasures for public health emergencies and biological threats. The company’s flagship product, TPOXX® (tecovirimat), is the first and only antiviral approved by the U.S. Food and Drug Administration for the treatment of smallpox. Siga has entered into procurement and development contracts with U.S. government agencies, including the Biomedical Advanced Research and Development Authority (BARDA) and the Department of Defense, to supply TPOXX® for the Strategic National Stockpile.
Founded in 2002, Siga has built a pipeline of therapies targeting high-consequence pathogens such as smallpox, plague and other potential biothreat agents. In addition to its commercial-stage TPOXX® program, the company is advancing earlier-stage candidates and manufacturing capabilities to support rapid scale-up in emergency scenarios. Siga’s research and development efforts draw on proprietary formulations and delivery technologies designed to meet stringent regulatory and biodefense requirements.
Headquartered in Corvallis, Oregon, with additional offices in New York, Siga serves government and public health agencies in North America and Europe. The company maintains a state-licensed manufacturing facility capable of producing large-scale quantities of its antiviral products. Through collaborations with international health organizations, Siga contributes to global preparedness initiatives for emerging viral diseases, including recent efforts around monkeypox and other orthopoxviruses.
Siga Technologies is led by a management team with extensive experience in pharmaceuticals, biodefense and regulatory affairs. The company holds multiple U.S. and international patents covering its antiviral compounds and formulations, positioning it as a key supplier of strategic medical countermeasures in both government stockpiles and broader public health programs.
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