Sionna Therapeutics (SION) Competitors $21.57 +0.61 (+2.91%) As of 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock SION vs. AAPG, MRUS, ACLX, SWTX, RNA, ACAD, SRRK, PTGX, VKTX, and MLTXShould you be buying Sionna Therapeutics stock or one of its competitors? The main competitors of Sionna Therapeutics include Ascentage Pharma Group International (AAPG), Merus (MRUS), Arcellx (ACLX), SpringWorks Therapeutics (SWTX), Avidity Biosciences (RNA), ACADIA Pharmaceuticals (ACAD), Scholar Rock (SRRK), Protagonist Therapeutics (PTGX), Viking Therapeutics (VKTX), and MoonLake Immunotherapeutics (MLTX). These companies are all part of the "pharmaceutical products" industry. Sionna Therapeutics vs. Its Competitors Ascentage Pharma Group International Merus Arcellx SpringWorks Therapeutics Avidity Biosciences ACADIA Pharmaceuticals Scholar Rock Protagonist Therapeutics Viking Therapeutics MoonLake Immunotherapeutics Sionna Therapeutics (NASDAQ:SION) and Ascentage Pharma Group International (NASDAQ:AAPG) are both medical companies, but which is the better investment? We will compare the two companies based on the strength of their dividends, institutional ownership, valuation, risk, analyst recommendations, media sentiment, earnings and profitability. Does the media refer more to SION or AAPG? In the previous week, Ascentage Pharma Group International had 1 more articles in the media than Sionna Therapeutics. MarketBeat recorded 4 mentions for Ascentage Pharma Group International and 3 mentions for Sionna Therapeutics. Sionna Therapeutics' average media sentiment score of 1.38 beat Ascentage Pharma Group International's score of 0.23 indicating that Sionna Therapeutics is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Sionna Therapeutics 2 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Ascentage Pharma Group International 1 Very Positive mention(s) 0 Positive mention(s) 3 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Neutral Is SION or AAPG more profitable? Company Net Margins Return on Equity Return on Assets Sionna TherapeuticsN/A N/A N/A Ascentage Pharma Group International N/A N/A N/A Which has higher earnings & valuation, SION or AAPG? Ascentage Pharma Group International has higher revenue and earnings than Sionna Therapeutics. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioSionna TherapeuticsN/AN/A-$61.69MN/AN/AAscentage Pharma Group International$134.35M26.81-$55.54MN/AN/A Do analysts prefer SION or AAPG? Sionna Therapeutics currently has a consensus price target of $38.50, suggesting a potential upside of 78.49%. Given Sionna Therapeutics' higher probable upside, research analysts plainly believe Sionna Therapeutics is more favorable than Ascentage Pharma Group International.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Sionna Therapeutics 0 Sell rating(s) 0 Hold rating(s) 3 Buy rating(s) 0 Strong Buy rating(s) 3.00Ascentage Pharma Group International 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 3.00 SummarySionna Therapeutics and Ascentage Pharma Group International tied by winning 3 of the 6 factors compared between the two stocks. Get Sionna Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for SION and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SION and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SION vs. The Competition Export to ExcelMetricSionna TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$924.85M$2.88B$5.47B$8.95BDividend YieldN/A2.46%5.25%4.06%P/E RatioN/A20.8027.0020.10Price / SalesN/A286.98435.75120.29Price / CashN/A41.1936.8257.86Price / BookN/A7.487.985.56Net Income-$61.69M-$55.04M$3.16B$248.40M7 Day Performance18.78%5.44%3.69%6.04%1 Month Performance25.26%2.38%2.91%7.69%1 Year PerformanceN/A5.53%34.30%20.97% Sionna Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SIONSionna TherapeuticsN/A$21.57+2.9%$38.50+78.5%N/A$924.85MN/A0.0035Positive NewsAAPGAscentage Pharma Group InternationalN/A$42.85+7.5%N/AN/A$3.73B$134.35M0.00600News CoverageGap DownMRUSMerus2.0892 of 5 stars$53.84+1.0%$84.64+57.2%-1.4%$3.73B$36.13M-13.2037Positive NewsACLXArcellx2.2837 of 5 stars$67.30+1.4%$111.23+65.3%+21.1%$3.71B$107.94M-22.5180SWTXSpringWorks Therapeutics1.5381 of 5 stars$46.99flat$52.57+11.9%N/A$3.54B$191.59M-13.78230RNAAvidity Biosciences2.4666 of 5 stars$29.13-0.8%$65.59+125.2%-26.2%$3.51B$10.90M-9.71190ACADACADIA Pharmaceuticals4.6689 of 5 stars$20.95-1.4%$27.88+33.1%+29.4%$3.51B$957.80M15.29510SRRKScholar Rock3.3041 of 5 stars$35.35-0.6%$42.67+20.7%+358.4%$3.36B$33.19M-13.97140PTGXProtagonist Therapeutics2.3249 of 5 stars$51.20+1.0%$66.10+29.1%+47.9%$3.17B$434.43M68.27120VKTXViking Therapeutics3.8522 of 5 stars$28.12+1.4%$87.15+210.0%-46.3%$3.16BN/A-24.4520MLTXMoonLake Immunotherapeutics1.982 of 5 stars$48.98+2.3%$74.50+52.1%+13.0%$3.13BN/A-21.292 Related Companies and Tools Related Companies AAPG Alternatives MRUS Alternatives ACLX Alternatives SWTX Alternatives RNA Alternatives ACAD Alternatives SRRK Alternatives PTGX Alternatives VKTX Alternatives MLTX Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SION) was last updated on 7/8/2025 by MarketBeat.com Staff From Our PartnersMarket Panic: Trump Just Dropped a Bomb on Your Stockstock Market Panic: Trump Just Dropped a Bomb on Your Stocks The market is in freefall—and Trump's new tarif...American Alternative | SponsoredThis Signal Only Flashes Once Every 4 Years – And It Just TriggeredThis same signal has appeared twice before in the past 8 years — both times, it kicked off major moves in cryp...Crypto Swap Profits | SponsoredINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredEveryone’s watching Nvidia right now. 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