Acelyrin (SLRN) Competitors $2.20 0.00 (0.00%) Closing price 04/17/2025 04:00 PM EasternExtended Trading$2.18 -0.02 (-0.68%) As of 04/17/2025 04:39 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock SLRN vs. WVE, COLL, ELVN, DYN, GPCR, ETNB, CMRX, CDMO, RCUS, and VIRShould you be buying Acelyrin stock or one of its competitors? The main competitors of Acelyrin include Wave Life Sciences (WVE), Collegium Pharmaceutical (COLL), Enliven Therapeutics (ELVN), Dyne Therapeutics (DYN), Structure Therapeutics (GPCR), 89bio (ETNB), Chimerix (CMRX), Avid Bioservices (CDMO), Arcus Biosciences (RCUS), and Vir Biotechnology (VIR). These companies are all part of the "pharmaceutical products" industry. Acelyrin vs. Wave Life Sciences Collegium Pharmaceutical Enliven Therapeutics Dyne Therapeutics Structure Therapeutics 89bio Chimerix Avid Bioservices Arcus Biosciences Vir Biotechnology Acelyrin (NASDAQ:SLRN) and Wave Life Sciences (NASDAQ:WVE) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their profitability, valuation, dividends, community ranking, earnings, risk, media sentiment, analyst recommendations and institutional ownership. Does the MarketBeat Community prefer SLRN or WVE? Wave Life Sciences received 351 more outperform votes than Acelyrin when rated by MarketBeat users. Likewise, 67.84% of users gave Wave Life Sciences an outperform vote while only 55.17% of users gave Acelyrin an outperform vote. CompanyUnderperformOutperformAcelyrinOutperform Votes1655.17% Underperform Votes1344.83% Wave Life SciencesOutperform Votes36767.84% Underperform Votes17432.16% Do analysts rate SLRN or WVE? Acelyrin presently has a consensus target price of $9.60, indicating a potential upside of 336.36%. Wave Life Sciences has a consensus target price of $22.18, indicating a potential upside of 274.69%. Given Acelyrin's higher possible upside, equities analysts clearly believe Acelyrin is more favorable than Wave Life Sciences.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Acelyrin 0 Sell rating(s) 3 Hold rating(s) 2 Buy rating(s) 0 Strong Buy rating(s) 2.40Wave Life Sciences 0 Sell rating(s) 1 Hold rating(s) 9 Buy rating(s) 1 Strong Buy rating(s) 3.00 Is SLRN or WVE more profitable? Acelyrin has a net margin of 0.00% compared to Wave Life Sciences' net margin of -66.50%. Acelyrin's return on equity of -44.12% beat Wave Life Sciences' return on equity.Company Net Margins Return on Equity Return on Assets AcelyrinN/A -44.12% -39.02% Wave Life Sciences -66.50%-280.57%-52.90% Which has better valuation & earnings, SLRN or WVE? Wave Life Sciences has higher revenue and earnings than Acelyrin. Wave Life Sciences is trading at a lower price-to-earnings ratio than Acelyrin, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAcelyrinN/AN/A-$381.64M-$2.50-0.88Wave Life Sciences$108.30M8.39-$57.51M-$0.79-7.49 Does the media prefer SLRN or WVE? In the previous week, Wave Life Sciences had 16 more articles in the media than Acelyrin. MarketBeat recorded 20 mentions for Wave Life Sciences and 4 mentions for Acelyrin. Acelyrin's average media sentiment score of 1.07 beat Wave Life Sciences' score of 0.73 indicating that Acelyrin is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Acelyrin 2 Very Positive mention(s) 0 Positive mention(s) 1 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Wave Life Sciences 9 Very Positive mention(s) 0 Positive mention(s) 2 Neutral mention(s) 2 Negative mention(s) 0 Very Negative mention(s) Positive Which has more risk and volatility, SLRN or WVE? Acelyrin has a beta of 1.12, suggesting that its stock price is 12% more volatile than the S&P 500. Comparatively, Wave Life Sciences has a beta of -0.93, suggesting that its stock price is 193% less volatile than the S&P 500. Do institutionals and insiders believe in SLRN or WVE? 87.3% of Acelyrin shares are owned by institutional investors. Comparatively, 89.7% of Wave Life Sciences shares are owned by institutional investors. 13.6% of Acelyrin shares are owned by company insiders. Comparatively, 29.1% of Wave Life Sciences shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term. SummaryWave Life Sciences beats Acelyrin on 11 of the 18 factors compared between the two stocks. Get Acelyrin News Delivered to You Automatically Sign up to receive the latest news and ratings for SLRN and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SLRN vs. The Competition Export to ExcelMetricAcelyrinPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$222.00M$6.44B$5.29B$7.35BDividend YieldN/A3.23%5.12%4.31%P/E Ratio-0.896.8821.7317.77Price / SalesN/A231.02379.1697.65Price / CashN/A65.6738.2234.64Price / Book0.335.916.443.98Net Income-$381.64M$142.72M$3.21B$247.44M7 Day Performance-1.35%4.33%2.82%1.82%1 Month Performance-21.99%-12.80%-8.67%-6.98%1 Year Performance-54.92%-9.71%11.32%1.49% Acelyrin Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SLRNAcelyrin3.5447 of 5 stars$2.20flat$9.60+336.4%-56.2%$222.00MN/A-0.89135Short Interest ↓Positive NewsWVEWave Life Sciences4.1846 of 5 stars$5.80-3.8%$22.60+289.7%+23.6%$890.22M$108.30M-5.23240Short Interest ↑News CoverageCOLLCollegium Pharmaceutical4.1875 of 5 stars$27.38-2.7%$43.60+59.2%-23.8%$879.77M$631.45M11.80210Positive NewsELVNEnliven Therapeutics2.6447 of 5 stars$17.87-4.4%$38.75+116.8%-4.5%$875.70MN/A-9.4150Gap DownDYNDyne Therapeutics3.5447 of 5 stars$7.49-9.5%$47.46+533.7%-67.1%$847.28MN/A-2.10100GPCRStructure Therapeutics2.5906 of 5 stars$14.31-5.4%$81.29+468.0%-41.3%$820.58MN/A-19.34136News CoverageGap UpETNB89bio2.5768 of 5 stars$5.49-4.9%$27.56+401.9%-33.8%$801.45MN/A-1.8940Short Interest ↑High Trading VolumeCMRXChimerix2.7747 of 5 stars$8.52-0.1%$8.53+0.2%+844.7%$799.21M$212,000.00-9.0690Analyst ForecastNews CoverageCDMOAvid Bioservices0.8311 of 5 stars$12.50+0.1%$12.25-2.0%+86.2%$799.18M$139.91M-5.23320Upcoming EarningsHigh Trading VolumeRCUSArcus Biosciences2.3869 of 5 stars$7.28+5.9%$30.25+315.8%-46.8%$764.88M$258M-2.31500Positive NewsHigh Trading VolumeVIRVir Biotechnology2.5104 of 5 stars$5.52-1.1%$35.67+546.1%-33.3%$757.03M$63.71M-1.41580Analyst ForecastShort Interest ↑ Related Companies and Tools Related Companies WVE Alternatives COLL Alternatives ELVN Alternatives DYN Alternatives GPCR Alternatives ETNB Alternatives CMRX Alternatives CDMO Alternatives RCUS Alternatives VIR Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SLRN) was last updated on 4/18/2025 by MarketBeat.com Staff From Our PartnersThe Last Time Stocks Looked Like This, They Didn’t Move For 16 YearsThere is nothing the Federal Reserve can do to stop what's coming next for U.S. stocks. 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