SOPHiA GENETICS (SOPH) Competitors $3.61 +0.17 (+4.94%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$3.60 -0.01 (-0.42%) As of 08/22/2025 07:18 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesOwnershipSEC FilingsShort InterestTrendsBuy This Stock SOPH vs. TRVI, URGN, IMNM, PHAR, QURE, AKBA, AVXL, ATAI, SANA, and OCSShould you be buying SOPHiA GENETICS stock or one of its competitors? The main competitors of SOPHiA GENETICS include Trevi Therapeutics (TRVI), Urogen Pharma (URGN), Immunome (IMNM), Pharming Group (PHAR), uniQure (QURE), Akebia Therapeutics (AKBA), Anavex Life Sciences (AVXL), atai Life Sciences (ATAI), Sana Biotechnology (SANA), and Oculis (OCS). These companies are all part of the "pharmaceutical products" industry. SOPHiA GENETICS vs. Its Competitors Trevi Therapeutics Urogen Pharma Immunome Pharming Group uniQure Akebia Therapeutics Anavex Life Sciences atai Life Sciences Sana Biotechnology Oculis SOPHiA GENETICS (NASDAQ:SOPH) and Trevi Therapeutics (NASDAQ:TRVI) are both small-cap medical companies, but which is the superior business? We will contrast the two companies based on the strength of their risk, media sentiment, dividends, profitability, analyst recommendations, valuation, institutional ownership and earnings. Do insiders and institutionals believe in SOPH or TRVI? 31.6% of SOPHiA GENETICS shares are owned by institutional investors. Comparatively, 95.8% of Trevi Therapeutics shares are owned by institutional investors. 4.9% of SOPHiA GENETICS shares are owned by insiders. Comparatively, 18.3% of Trevi Therapeutics shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a stock is poised for long-term growth. Do analysts recommend SOPH or TRVI? SOPHiA GENETICS presently has a consensus price target of $8.00, indicating a potential upside of 121.61%. Trevi Therapeutics has a consensus price target of $20.11, indicating a potential upside of 166.37%. Given Trevi Therapeutics' stronger consensus rating and higher probable upside, analysts plainly believe Trevi Therapeutics is more favorable than SOPHiA GENETICS.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score SOPHiA GENETICS 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 0 Strong Buy rating(s) 3.00Trevi Therapeutics 0 Sell rating(s) 0 Hold rating(s) 8 Buy rating(s) 2 Strong Buy rating(s) 3.20 Which has preferable earnings & valuation, SOPH or TRVI? Trevi Therapeutics has lower revenue, but higher earnings than SOPHiA GENETICS. Trevi Therapeutics is trading at a lower price-to-earnings ratio than SOPHiA GENETICS, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioSOPHiA GENETICS$65.17M3.74-$62.49M-$0.44-8.20Trevi TherapeuticsN/AN/A-$47.91M-$0.42-17.98 Is SOPH or TRVI more profitable? Trevi Therapeutics has a net margin of 0.00% compared to SOPHiA GENETICS's net margin of -40.99%. SOPHiA GENETICS's return on equity of -30.69% beat Trevi Therapeutics' return on equity.Company Net Margins Return on Equity Return on Assets SOPHiA GENETICS-40.99% -30.69% -17.39% Trevi Therapeutics N/A -41.44%-38.21% Which has more volatility and risk, SOPH or TRVI? SOPHiA GENETICS has a beta of 1, meaning that its stock price has a similar volatility profile to the S&P 500.Comparatively, Trevi Therapeutics has a beta of 0.58, meaning that its stock price is 42% less volatile than the S&P 500. Does the media favor SOPH or TRVI? In the previous week, Trevi Therapeutics had 9 more articles in the media than SOPHiA GENETICS. MarketBeat recorded 10 mentions for Trevi Therapeutics and 1 mentions for SOPHiA GENETICS. SOPHiA GENETICS's average media sentiment score of 1.92 beat Trevi Therapeutics' score of 0.80 indicating that SOPHiA GENETICS is being referred to more favorably in the media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment SOPHiA GENETICS 1 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Very Positive Trevi Therapeutics 1 Very Positive mention(s) 1 Positive mention(s) 3 Neutral mention(s) 1 Negative mention(s) 0 Very Negative mention(s) Positive SummaryTrevi Therapeutics beats SOPHiA GENETICS on 10 of the 16 factors compared between the two stocks. Get SOPHiA GENETICS News Delivered to You Automatically Sign up to receive the latest news and ratings for SOPH and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding SOPH and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart SOPH vs. The Competition Export to ExcelMetricSOPHiA GENETICSMEDICAL INFO SYS IndustryMedical SectorNASDAQ ExchangeMarket Cap$243.96M$2.15B$5.81B$9.76BDividend YieldN/AN/A4.39%4.06%P/E Ratio-8.2038.6631.3626.05Price / Sales3.7450.62387.8788.42Price / CashN/A53.5538.0259.36Price / Book3.196.709.536.60Net Income-$62.49M-$63.67M$3.26B$265.65M7 Day Performance4.03%4.61%2.14%2.00%1 Month PerformanceN/A1.26%3.22%0.46%1 Year Performance-3.48%26.44%30.18%18.88% SOPHiA GENETICS Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)SOPHSOPHiA GENETICS2.946 of 5 stars$3.61+4.9%$8.00+121.6%-3.5%$243.96M$65.17M-8.20520Positive NewsGap UpTRVITrevi Therapeutics3.0791 of 5 stars$7.38-1.0%$20.38+176.3%+152.5%$894.72MN/A-17.4920Analyst ForecastURGNUrogen Pharma4.5365 of 5 stars$19.22-0.9%$32.00+66.5%+37.3%$891.79M$91.87M-5.81200IMNMImmunome1.8134 of 5 stars$9.88-3.6%$23.14+134.2%-33.3%$859.96M$9.04M-3.2140News CoverageAnalyst ForecastGap UpPHARPharming Group2.3672 of 5 stars$12.47+0.7%$30.00+140.5%+80.3%$848.57M$297.20M-95.28280Gap UpQUREuniQure2.4631 of 5 stars$15.18-3.1%$37.45+146.8%+153.6%$830.36M$14.34M-3.86500Analyst RevisionAKBAAkebia Therapeutics3.9403 of 5 stars$3.05-2.1%$6.75+121.7%+108.5%$807.37M$203.73M-17.91430Analyst RevisionAVXLAnavex Life Sciences3.7642 of 5 stars$9.40-2.0%$44.00+368.1%+50.8%$805.69MN/A-16.4640Analyst ForecastATAIatai Life Sciences3.5953 of 5 stars$3.98-1.9%$11.25+183.0%+248.9%$796.35M$310K-5.7680Analyst DowngradeAnalyst RevisionGap UpSANASana Biotechnology2.9545 of 5 stars$3.31-2.8%$8.00+142.1%-38.7%$785.96MN/A-3.12380OCSOculis2.9945 of 5 stars$17.90-0.9%$35.33+97.4%+49.6%$781.95M$780K-6.782News CoverageEarnings ReportAnalyst Forecast Related Companies and Tools Related Companies TRVI Alternatives URGN Alternatives IMNM Alternatives PHAR Alternatives QURE Alternatives AKBA Alternatives AVXL Alternatives ATAI Alternatives SANA Alternatives OCS Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:SOPH) was last updated on 8/24/2025 by MarketBeat.com Staff From Our PartnersGENIUS Act: Cancel Your Money?A new law called the GENIUS Act could quietly trigger the most radical shift in American finance in decades. 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