Positive News SentimentPositive NewsNASDAQ:SPRB Spruce Biosciences (SPRB) Stock Price, News & Analysis $0.38 +0.00 (+0.97%) As of 09:30 AM Eastern Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrends About Spruce Biosciences Stock (NASDAQ:SPRB) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Spruce Biosciences alerts:Sign Up Key Stats Today's Range$0.38▼$0.3950-Day Range$0.36▼$0.5552-Week Range$0.34▼$5.95Volume12,918 shsAverage Volume757,158 shsMarket Capitalization$15.49 millionP/E RatioN/ADividend YieldN/APrice Target$3.90Consensus RatingHold Company OverviewSpruce Biosciences, Inc., a biopharmaceutical company, focuses on developing and commercializing novel therapies for rare endocrine disorders. The company engages in developing tildacerfont, a non-steroidal therapy to enhance disease control and reduce steroid burden for patients suffering from congenital adrenal hyperplasia (CAH), which is in Phase 2b clinical trial; and to evaluate glucocorticoid reduction in adult patients with classic CAH that is Phase 2b clinical trial. It is also developing tildacerfont for the treatment of pediatric classic congenital adrenal hyperplasia in children that is in Phase 2 clinical trial; and for females with polycystic ovary syndrome, which is in Phase 2 clinical trial. Spruce Biosciences, Inc. has a license agreement with Eli Lilly and Company to research, develop, and commercialize compounds for various pharmaceutical uses; and collaboration and license agreement with Kaken Pharmaceutical Co. Ltd. to develop, manufacture, and commercialize tildacerfont for the treatment of CAH in Japan. The company was incorporated in 2014 and is headquartered in South San Francisco, California.Read More… Spruce Biosciences Stock Analysis - MarketRank™See Top Rated MarketRank™ Stocks81st Percentile Overall ScoreSPRB MarketRank™: Spruce Biosciences scored higher than 81% of companies evaluated by MarketBeat, and ranked 229th out of 955 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion4.0 / 5Analyst RatingHold Consensus RatingSpruce Biosciences has received a consensus rating of Hold. The company's average rating score is 2.00, and is based on no buy ratings, 9 hold ratings, and no sell ratings.Amount of Analyst CoverageSpruce Biosciences has been the subject of 6 research reports in the past 90 days, demonstrating strong analyst interest in this stock.Read more about Spruce Biosciences' stock forecast and price target. Earnings and Valuation1.3 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Spruce Biosciences are expected to grow in the coming year, from ($1.03) to ($0.99) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Spruce Biosciences is -0.40, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Spruce Biosciences is -0.40, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Book Value per Share RatioSpruce Biosciences has a P/B Ratio of 0.20. P/B Ratios below 1 indicate that a company could be undervalued with respect to its assets and liabilities. Short Interest5.0 / 5Short Interest LevelHealthy Percentage of Shares Shorted0.26% of the outstanding shares of Spruce Biosciences have been sold short.Short Interest Ratio / Days to CoverSpruce Biosciences has a short interest ratio ("days to cover") of 0.2, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Spruce Biosciences has recently decreased by 51.10%, indicating that investor sentiment is improving significantly. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldSpruce Biosciences does not currently pay a dividend.Dividend GrowthSpruce Biosciences does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Percentage of Shares Shorted0.26% of the outstanding shares of Spruce Biosciences have been sold short.Short Interest Ratio / Days to CoverSpruce Biosciences has a short interest ratio ("days to cover") of 0.2, which is generally considered an acceptable ratio of short interest to trading volume.Change versus previous monthShort interest in Spruce Biosciences has recently decreased by 51.10%, indicating that investor sentiment is improving significantly. News and Social Media3.1 / 5News Sentiment1.59 News SentimentSpruce Biosciences has a news sentiment score of 1.59. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a higher news sentiment than the 0.78 average news sentiment score of Medical companies.News Coverage This WeekMarketBeat has tracked 2 news articles for Spruce Biosciences this week, compared to 1 article on an average week.Search InterestOnly 1 people have searched for SPRB on MarketBeat in the last 30 days. This is a decrease of 0% compared to the previous 30 days. Company Ownership1.7 / 5Insider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Spruce Biosciences insiders have not sold or bought any company stock.Percentage Held by InsidersOnly 9.10% of the stock of Spruce Biosciences is held by insiders.Percentage Held by Institutions91.71% of the stock of Spruce Biosciences is held by institutions. High institutional ownership can be a signal of strong market trust in this company.Read more about Spruce Biosciences' insider trading history. Receive SPRB Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Spruce Biosciences and its competitors with MarketBeat's FREE daily newsletter. Email Address SPRB Stock News HeadlinesHold Rating for Spruce Biosciences Amid Clinical Setbacks and Strategic UncertaintiesDecember 16, 2024 | markets.businessinsider.comJMP Securities Downgrades Spruce Biosciences (SPRB)December 12, 2024 | msn.comUnlock the Secret to Microsoft's Yearly GainsWhat would you do if you knew that you could have placed a trade on Microsoft every year on October 13th … And had the chance to pocket an impressive gain in a matter of days… And this didn’t work just once… Not twice… But it worked for an entire decade… According to market veteran Jack Carter’s research, the recurring phenomenon generated winner after winner for 10 straight years! All you had to do is wait for October 13th to roll around on the calendar… Then place a quick trade… Of course, we can’t promise profits or prevent losses… But you can get 10 FREE trade ideas from Jack, just like that one on Microsoft.January 15, 2025 | Jack Carter Trading (Ad)Spruce Biosciences Downgraded to Hold Amid Unmet Clinical Trial Endpoints and Strategic ReevaluationDecember 11, 2024 | markets.businessinsider.comOppenheimer Downgrades Spruce Biosciences (SPRB)December 11, 2024 | msn.comSpruce Biosciences Announces Topline Results from CAHmelia-204 in Adult CAH and CAHptain-205 in Adult and Pediatric CAHDecember 11, 2024 | finance.yahoo.comSpruce Biosciences CAHmelia-204 study did not achieve primary efficacy endpointDecember 11, 2024 | markets.businessinsider.comJMP Securities downgrades Spruce Biosciences (SPRB) to a HoldDecember 11, 2024 | markets.businessinsider.comSee More Headlines SPRB Stock Analysis - Frequently Asked Questions How have SPRB shares performed this year? Spruce Biosciences' stock was trading at $0.42 at the beginning of the year. Since then, SPRB stock has decreased by 10.7% and is now trading at $0.3750. View the best growth stocks for 2025 here. How were Spruce Biosciences' earnings last quarter? Spruce Biosciences, Inc. (NASDAQ:SPRB) posted its quarterly earnings results on Monday, November, 11th. The company reported ($0.21) EPS for the quarter, beating the consensus estimate of ($0.27) by $0.06. The business had revenue of $0.60 million for the quarter, compared to analysts' expectations of $1.80 million. Spruce Biosciences had a negative net margin of 555.23% and a negative trailing twelve-month return on equity of 62.10%. When did Spruce Biosciences IPO? Spruce Biosciences (SPRB) raised $75 million in an initial public offering on Friday, October 9th 2020. The company issued 5,000,000 shares at $14.00-$16.00 per share. Cowen, SVB Leerink, Credit Suisse and RBC Capital Markets acted as the underwriters for the IPO. How do I buy shares of Spruce Biosciences? Shares of SPRB stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. Compare Top Brokerages Here. What other stocks do shareholders of Spruce Biosciences own? Based on aggregate information from My MarketBeat watchlists, some other companies that Spruce Biosciences investors own include NVIDIA (NVDA), Broadcom (AVGO), Arista Networks (ANET), Jabil (JBL), Adobe (ADBE), Meta Platforms (META) and Disc Medicine (IRON). Company Calendar Last Earnings11/11/2024Today1/15/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNASDAQ SectorMedical Industry Pharmaceutical preparations Sub-IndustryPharmaceutical Products Current SymbolNASDAQ:SPRB CUSIPN/A CIK1683553 Webwww.sprucebiosciences.com Phone415-655-4168FaxN/AEmployees20Year FoundedN/APrice Target and Rating Average Stock Price Target$3.90 High Stock Price Target$10.00 Low Stock Price Target$1.50 Potential Upside/Downside+950.1%Consensus RatingHold Rating Score (0-4)2.00 Research Coverage9 Analysts Profitability EPS (Most Recent Fiscal Year)($0.94) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$-47,920,000.00 Net Margins-555.23% Pretax Margin-555.23% Return on Equity-62.10% Return on Assets-47.49% Debt Debt-to-Equity Ratio0.01 Current Ratio5.36 Quick Ratio5.36 Sales & Book Value Annual Sales$7.10 million Price / Sales2.16 Cash FlowN/A Price / Cash FlowN/A Book Value$1.88 per share Price / Book0.20Miscellaneous Outstanding Shares41,303,000Free Float37,544,000Market Cap$15.34 million OptionableOptionable Beta2.38 Ten Starter Stocks For Beginners to Buy NowJust getting into the stock market? 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