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Spyre Therapeutics (SYRE) Institutional Ownership

Spyre Therapeutics logo
$20.62 +0.07 (+0.34%)
As of 01/17/2025 04:00 PM Eastern
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Institutional Ownership Changes (13F Filings) for Spyre Therapeutics (NASDAQ:SYRE)

Current
Institutional Ownership
Percentage
80.39%
Number of
Institutional Buyers
(last 12 months)
43
Total
Institutional Inflows
(last 12 months)
$275.36M
Number of
Institutional Sellers
(last 12 months)
4
Total
Institutional Outflows
(last 12 months)
$35.98M
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SYRE Institutional Buying and Selling by Quarter

Spyre Therapeutics Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
1/14/2025 Assenagon Asset Management S.A.22,652$527K0.0%-98.0%0.044%
12/26/2024JPMorgan Chase & Co.29,473$867K0.0%+29.4%0.057%
11/27/2024Franklin Resources Inc.760,666$23.32M0.0%+2.5%1.479%
11/18/2024Teachers Retirement System of The State of Kentucky21,154$622K0.0%N/A0.041%
11/16/2024Geode Capital Management LLC891,048$26.21M0.0%+16.4%1.733%
11/15/2024Barclays PLC105,467$3.10M0.0%+64.7%0.205%
11/15/2024Jane Street Group LLC20,641$607K0.0%+78.7%0.040%
11/15/2024Wellington Management Group LLP1,507,200$44.33M0.0%+89.4%2.931%
11/15/2024State Street Corp1,541,555$45.34M0.0%+9.4%2.997%
11/15/2024Ikarian Capital LLC302,247$8.89M1.2%N/A0.588%
11/15/2024Janus Henderson Group PLC1,120,531$32.92M0.0%+66.3%2.179%
11/15/2024HighVista Strategies LLC105,351$3.10M1.1%-7.2%0.205%
11/15/2024Cinctive Capital Management LP61,256$1.80M0.1%N/A0.119%
11/14/2024Braidwell LP2,189,836$64.40M1.8%-12.9%4.258%
11/14/2024Walleye Capital LLC243,372$7.16M0.0%+61.4%0.473%
11/14/2024UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC26,441$778K0.0%-12.2%0.051%
11/14/2024MetLife Investment Management LLC20,132$592K0.0%+129.1%0.039%
11/13/2024FMR LLC7,623,881$224.22M0.0%+1.5%14.824%
11/13/2024The Manufacturers Life Insurance Company43,460$1.28M0.0%+15.0%0.085%
11/12/2024Charles Schwab Investment Management Inc.333,275$9.80M0.0%+239.4%0.655%
11/9/2024Intech Investment Management LLC8,371$246K0.0%N/A0.016%
11/7/2024Quest Partners LLC5,654$166K0.0%+271.2%0.011%
10/29/2024Emerald Advisers LLC292,569$8.60M0.3%N/A0.575%
10/29/2024Emerald Mutual Fund Advisers Trust253,550$7.46M0.4%N/A0.498%
10/23/2024 Assenagon Asset Management S.A.1,142,768$33.61M0.1%N/A2.837%
10/3/2024SG Americas Securities LLC12,589$370K0.0%+127.0%0.031%
8/16/2024Perceptive Advisors LLC3,031,018$71.26M1.7%+18.6%7.524%
8/16/2024Driehaus Capital Management LLC687,080$16.15M0.2%N/A1.706%
8/15/2024The Manufacturers Life Insurance Company37,782$888K0.0%N/A0.094%
8/15/2024Darwin Global Management Ltd.452,040$10.27M1.2%N/A1.122%
8/15/2024Armistice Capital LLC136,000$3.20M0.0%N/A0.338%
8/15/2024Affinity Asset Advisors LLC513,420$12.07M1.4%N/A1.275%
8/14/2024Great Point Partners LLC134,612$3.17M0.6%N/A0.334%
8/14/2024Logos Global Management LP575,000$13.52M1.1%N/A1.427%
8/14/2024Farallon Capital Management LLC666,000$15.66M0.1%N/A1.653%
8/14/2024Integral Health Asset Management LLC100,000$2.35M0.2%N/A0.248%
8/14/2024Avoro Capital Advisors LLC1,839,138$43.24M0.6%N/A4.566%
8/14/2024HighVista Strategies LLC113,550$2.67M1.0%N/A0.282%
8/14/2024Profund Advisors LLC12,606$296K0.0%N/A0.031%
8/13/2024Ensign Peak Advisors Inc82,475$1.94M0.0%N/A0.205%
8/12/2024Amalgamated Bank1,198$28K0.0%N/A0.003%
8/9/2024Carlyle Group Inc.9,620$227K0.0%N/A0.024%
8/8/2024First Turn Management LLC464,435$10.92M1.8%N/A1.153%
8/6/2024Quest Partners LLC1,523$36K0.0%N/A0.004%
8/6/2024Candriam S.C.A.105,000$2.47M0.0%N/A0.261%
8/3/2024TD Asset Management Inc35,168$827K0.0%N/A0.087%
8/1/2024Rhumbline Advisers51,896$1.22M0.0%N/A0.129%
7/26/2024Bank of New York Mellon Corp117,686$2.77M0.0%N/A0.292%
7/26/2024EFG Asset Management North America Corp.36,781$869K0.2%N/A0.091%
7/12/2024SG Americas Securities LLC5,545$130K0.0%N/A0.014%
(Data available from 1/1/2016 forward)

SYRE Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of SYRE shares?

During the previous two years, 45 institutional investors and hedge funds held shares of Spyre Therapeutics. The most heavily invested institutionals were FMR LLC ($224.22M), Perceptive Advisors LLC ($71.26M), Braidwell LP ($64.40M), State Street Corp ($45.34M), Wellington Management Group LLP ($44.33M), Avoro Capital Advisors LLC ($43.24M), and Janus Henderson Group PLC ($32.92M).Learn more on SYRE's institutional investors.

What percentage of Spyre Therapeutics stock is owned by institutional investors?

80.39% of Spyre Therapeutics stock is owned by institutional investors. Learn more on SYRE's institutional investor holdings.

Which institutional investors have been buying Spyre Therapeutics stock?

Of the 43 institutional investors that purchased Spyre Therapeutics stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: Avoro Capital Advisors LLC ($1.84M), Assenagon Asset Management S.A. ($1.14M), Wellington Management Group LLP ($711.25K), Driehaus Capital Management LLC ($687.08K), Farallon Capital Management LLC ($666K), Logos Global Management LP ($575K), and Affinity Asset Advisors LLC ($513.42K).

How much institutional buying is happening at Spyre Therapeutics?

Institutional investors have bought a total of 10,697,555 shares in the last 24 months. This purchase volume represents approximately $275.36M in transactions.

Which Spyre Therapeutics major shareholders have been selling company stock?

The following institutional investors have sold Spyre Therapeutics stock in the last 24 months: Assenagon Asset Management S.A. ($1.12M), Braidwell LP ($324.70K), HighVista Strategies LLC ($8.20K), and UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC ($3.68K).

How much institutional selling is happening at Spyre Therapeutics?

Institutional investors have sold a total of 1,456,697 shares in the last 24 months. This volume of shares sold represents approximately $35.98M in transactions.


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This page (NASDAQ:SYRE) was last updated on 1/18/2025 by MarketBeat.com Staff
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