Syros Pharmaceuticals (SYRS) Short Interest Ratio & Short Volume $0.0027 +0.00 (+3.85%) As of 02:05 PM Eastern Add Compare Share Share Short Interest Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock Syros Pharmaceuticals Short Interest DataSyros Pharmaceuticals (SYRS) has a short interest of 119,400 shares, representing 0.51% of the float (the number of shares available for trading by the public). This marks a -1.00% decrease in short interest from the previous month. The short interest ratio (days to cover) is 0.4, indicating that it would take 0.4 days of the average trading volume of 8.06 million shares to cover all short positions.Current Short Interest119,400 sharesPrevious Short Interest120,600 sharesChange Vs. Previous Month-1.00%Dollar Volume Sold Short$2.65 thousandShort Interest Ratio0.4 Days to CoverLast Record DateJune 30, 2025Outstanding Shares26,832,000 sharesShort Percent of Float0.51%Today's Trading Volume24,743 sharesAverage Trading Volume8,061,064 sharesToday's Volume Vs. Average0% Short Selling Syros Pharmaceuticals? Sign up to receive the latest short interest report for Syros Pharmaceuticals and its competitors with MarketBeat's FREE newsletter. Email Address Skip Charts & View Short Interest HistoryShort Interest ChartDays to Cover ChartShort Percent of Float ChartSYRS Short Interest Over TimeSYRS Days to Cover Over TimeSYRS Percentage of Float Shorted Over Time Syros Pharmaceuticals Short Interest History Export to ExcelReport DateTotal Shares Sold ShortDollar Volume Sold ShortChange from Previous ReportPercentage of Float ShortedDays to CoverPrice on Report Date 6/30/2025119,400 shares $2.65 thousand -1.0%0.5%0.4 $0.02 6/15/2025120,600 shares $2.69 thousand -6.7%0.5%0.5 $0.02 5/31/2025129,200 shares $3.48 thousand No Change0.5%0.4 $0.03 5/15/2025129,200 shares $4.07 thousand -60.7%N/A0.4 $0.03 4/30/2025329,100 shares $10.00 thousand -41.6%N/A0.8 $0.03 4/15/2025563,700 shares $14.09 thousand -3.7%N/A1 $0.03 3/15/20254,190,000 shares $387.16 thousand +345.9%17.7%0.2 $0.09 2/28/2025939,600 shares $134.55 thousand +2.9%4.0%0.1 $0.14 2/15/2025913,100 shares $168.92 thousand +26.3%3.9%0.4 $0.19 1/31/2025723,200 shares $126.70 thousand -47.2%4.2%0.1 $0.18 Get the Latest News and Ratings for SYRS and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Syros Pharmaceuticals and its competitors with MarketBeat's FREE daily newsletter. 1/15/20251,370,000 shares $326.20 thousand +24.6%7.9%0.1 $0.24 12/31/20241,100,000 shares $252.78 thousand -29.9%6.3%0.1 $0.23 12/15/20241,570,000 shares $325.30 thousand -29.6%9.0%0.2 $0.21 11/30/20242,230,000 shares $605.45 thousand -53.3%12.8%0.3 $0.27 11/15/20244,770,000 shares $1.24 million +281.6%27.7%0.6 $0.26 10/31/20241,250,000 shares $3.15 million +31.2%6.4%2.8 $2.52 10/15/2024952,600 shares $1.90 million -4.7%4.8%2.5 $1.99 9/30/2024999,900 shares $2.15 million -9.1%5.1%3.1 $2.15 9/15/20241,100,000 shares $2.15 million +14.9%5.6%3.6 $1.95 8/31/2024957,500 shares $1.57 million -22.8%4.8%4 $1.64 8/15/20241,240,000 shares $1.90 million -6.8%6.2%5.3 $1.53 7/31/20241,330,000 shares $7.98 million +4.7%6.7%12.9 $6.00 7/15/20241,270,000 shares $7.80 million -3.1%6.4%12.5 $6.14 6/30/20241,310,000 shares $6.76 million +4.0%6.6%9.8 $5.16 6/15/20241,260,000 shares $7.56 million -4.6%6.4%7.8 $6.00 5/31/20241,320,000 shares $6.73 million -13.2%6.6%8 $5.10 5/15/20241,520,000 shares $8.38 million +4.8%7.6%8 $5.51 4/30/20241,450,000 shares $7.83 million -22.0%7.8%7.4 $5.40 4/15/20241,860,000 shares $9.95 million +2.2%10.1%8.5 $5.35 3/31/20241,820,000 shares $9.74 million +4.6%9.9%8.4 $5.35 3/15/20241,740,000 shares $10.46 million +31.8%9.6%8.2 $6.01 2/29/20241,320,000 shares $9.58 million +29.4%7.3%4.1 $7.26 2/15/20241,020,000 shares $7.22 million +38.1%5.6%3.4 $7.08 1/31/2024738,800 shares $5.28 million +27.1%3.6%2.6 $7.14 1/15/2024581,200 shares $4.21 million +18.5%2.8%2.2 $7.24 12/31/2023490,600 shares $3.82 million -2.6%2.5%2.1 $7.79 12/15/2023503,500 shares $2.09 million +2.1%2.5%2.5 $4.16 11/30/2023493,400 shares $1.36 million +0.3%3.0%3.2 $2.75 11/15/2023491,800 shares $1.50 million -11.1%3.0%8.5 $3.04 10/31/2023553,100 shares $1.38 million -9.5%3.4%9.3 $2.49INVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting Off (Ad)Right now, we’re witnessing a monumental shift in the world.Our No. 1 AI Pick is currently trading for pennies on the dollar compared to Nividia. 10/15/2023611,200 shares $1.58 million -5.6%3.8%10.5 $2.59 9/30/2023647,300 shares $2.56 million +8.7%4.0%10.7 $3.95 9/15/2023595,500 shares $2.34 million -4.2%3.7%9.7 $3.93 8/31/2023621,800 shares $2.43 million -0.1%3.8%9.9 $3.90 8/15/2023622,600 shares $2.37 million -6.4%3.8%9.3 $3.81 7/31/2023665,000 shares $2.65 million +0.8%3.6%9 $3.98 7/15/2023660,000 shares $2.21 million +2.9%3.6%8.5 $3.35 6/30/2023641,500 shares $2.02 million +1.9%3.5%8.2 $3.15 6/15/2023629,700 shares $2.04 million +0.6%3.5%7.7 $3.24 5/31/2023625,800 shares $2.41 million -0.7%4.0%6.2 $3.85 5/15/2023630,200 shares $2.37 million -4.9%4.0%5.8 $3.76 4/30/2023662,700 shares $2.11 million -6.2%4.4%6.3 $3.18 4/15/2023706,700 shares $1.91 million -2.4%4.7%5.5 $2.70 3/31/2023724,200 shares $1.93 million +11.5%4.8%5.5 $2.67 3/15/2023649,500 shares $2.01 million +21.6%4.3%4.9 $3.09 2/28/2023534,300 shares $2.01 million -5.9%3.6%4.4 $3.76 2/15/2023567,600 shares $2.35 million -7.7%3.8%4.8 $4.14 1/31/2023615,100 shares $3.14 million +5.2%3.8%4.9 $5.11 1/15/2023584,700 shares $2.79 million -39.4%3.7%5.4 $4.77 12/30/2022964,400 shares $3.46 million +1.9%6.0%8.3 $3.59 12/15/2022946,500 shares $3.43 million +13.2%5.9%7.6 $3.62 11/30/2022836,400 shares $3.31 million +1.6%5.2%3.3 $3.96 11/15/2022823,300 shares $3.30 million +21.8%5.1%3.4 $4.01 10/31/2022676,000 shares $3.39 million +11.1%3.4%2.9 $5.02 10/15/2022608,700 shares $3.51 million -13.7%3.1%2.6 $5.77 9/30/2022705,200 shares $4.54 million -9.1%8.9%3.2 $6.44 9/15/2022775,700 shares $5.66 million -79.9%12.6%3.6 $7.29 8/31/20223,850,000 shares $3.08 million +5.2%14.3%5.3 $0.80 8/15/20223,660,000 shares $3.70 million +78.5%13.6%4.5 $1.01 7/31/20222,050,000 shares $1.61 million No Change7.6%2.4 $0.79 7/15/20222,050,000 shares $1.92 million +31.4%7.6%2.4 $0.94 6/30/20221,560,000 shares $1.50 million -53.3%3.5%1.7 $0.96 6/15/20223,340,000 shares $3.57 million -4.8%7.5%3.3 $1.07 5/31/20223,510,000 shares $2.89 million -14.8%8.0%3.9 $0.82 5/15/20224,120,000 shares $3.70 million +9.6%9.4%5 $0.90 4/30/20223,760,000 shares $3.17 million +29.7%9.0%4.9 $0.84 4/15/20222,900,000 shares $2.63 million -9.4%7.0%3.9 $0.91 3/31/20223,200,000 shares $3.81 million -4.8%7.8%5.4 $1.19 3/15/20223,360,000 shares $3.73 million -18.8%8.2%7 $1.11 2/28/20224,140,000 shares $5.34 million +1.7%10.1%9.3 $1.29 2/15/20224,070,000 shares $6.47 million -4.7%9.9%9.4 $1.59 1/31/20224,270,000 shares $8.45 million +4.4%10.9%10 $1.98 1/15/20224,090,000 shares $11.00 million +19.6%10.5%11.6 $2.69 12/31/20213,420,000 shares $11.15 million No Change8.8%10.2 $3.26 12/15/20213,420,000 shares $11.97 million -7.6%8.8%9.4 $3.50 11/30/20213,700,000 shares $14.65 million +3.6%9.5%8.2 $3.96 11/15/20213,570,000 shares $15.21 million -7.0%9.2%7.6 $4.26 10/29/20213,840,000 shares $15.86 million -6.8%9.8%8.1 $4.13 10/15/20214,120,000 shares $18.66 million +1.7%10.5%8.1 $4.53 9/30/20214,050,000 shares $18.10 million -6.0%10.3%7 $4.47INVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting Off (Ad)Right now, we’re witnessing a monumental shift in the world.Our No. 1 AI Pick is currently trading for pennies on the dollar compared to Nividia. 9/15/20214,310,000 shares $22.58 million -2.9%11.0%6.5 $5.24 8/31/20214,440,000 shares $23.53 million No Change11.3%6 $5.30 8/13/20214,440,000 shares $20.34 million +2.1%11.3%3.6 $4.58 7/30/20214,350,000 shares $20.10 million +9.9%10.8%3.2 $4.62 7/15/20213,960,000 shares $18.14 million -17.2%9.4%2.9 $4.58 6/30/20214,780,000 shares $26.05 million -2.3%11.4%3.5 $5.45 6/15/20214,890,000 shares $28.07 million -14.4%11.7%3.6 $5.74 5/28/20215,710,000 shares $36.83 million -6.6%13.7%4.6 $6.45 5/14/20216,110,000 shares $31.10 million +15.7%14.6%6.8 $5.09 4/30/20215,280,000 shares $32.95 million +7.8%12.5%7.4 $6.24 4/15/20214,900,000 shares $32.49 million -9.4%11.6%6.9 $6.63 3/31/20215,410,000 shares $39.20 million +10.9%12.8%7.1 $7.25 3/15/20214,880,000 shares $43.82 million +21.1%11.6%6.2 $8.98 2/26/20214,030,000 shares $35.79 million +10.7%9.6%5 $8.88 2/12/20213,640,000 shares $42.77 million -4.0%8.7%4.9 $11.75 1/29/20213,790,000 shares $40.36 million +7.7%N/A5.4 $10.65 1/15/20213,520,000 shares $48.68 million No ChangeN/A4.9 $13.83 12/31/20203,520,000 shares $41.78 million -22.8%8.8%5.6 $11.87 12/15/20204,560,000 shares $53.12 million +2.0%14.0%7.8 $11.65 11/30/20204,470,000 shares $36.43 million -3.7%11.3%8.8 $8.15 11/15/20204,640,000 shares $40.74 million -20.6%11.7%10 $8.78 10/30/20205,840,000 shares $40.18 million +4.1%14.7%12 $6.88 10/15/20205,610,000 shares $50.01 million +15.7%14.2%13.5 $8.92 9/30/20204,850,000 shares $42.87 million +31.1%12.2%13 $8.84 9/15/20203,700,000 shares $38.48 million +2.2%9.3%9.9 $10.40 8/31/20203,620,000 shares $47.97 million +31.2%9.1%9.9 $13.25 8/14/20202,760,000 shares $32.87 million -4.8%7.0%7.9 $11.91 7/31/20202,900,000 shares $27.52 million -1.4%8.2%9 $9.49 SYRS Short Interest - Frequently Asked Questions What is Syros Pharmaceuticals' current short interest? Short interest is the volume of Syros Pharmaceuticals shares that have been sold short but have not yet been covered or closed out. As of June 30th, traders have sold 119,400 shares of SYRS short. 0.51% of Syros Pharmaceuticals' shares are currently sold short. Learn More on Syros Pharmaceuticals' current short interest. Which institutional investors are shorting Syros Pharmaceuticals? As of the most recent reporting period, the following institutional investors, funds, and major shareholders have reported short positions of Syros Pharmaceuticals: Torno Capital LLC, Affinity Asset Advisors LLC, and FNY Investment Advisers LLC. These positions are disclosed in Form 13F filings with the Securities and Exchange Commission. What is a good short interest percentage for Syros Pharmaceuticals? Companies that have a short interest as a percentage of float below 10% indicates positive investor sentiment and few short sellers. Stocks with a short interest percentage above 10% is considered high, suggesting some investors are pessimistic about the stock. Companies with a short interest percentage of 20% or more indicates widespread negative sentiment. 0.51% of Syros Pharmaceuticals' floating shares are currently sold short. Is Syros Pharmaceuticals' short interest increasing or decreasing? Syros Pharmaceuticals saw a decrease in short interest during the month of June. As of June 30th, there was short interest totaling 119,400 shares, a decrease of 1.0% from the previous total of 120,600 shares. Changes in short volume can be used to identify positive and negative investor sentiment. Investors that short sell a stock are betting that its price will decline in the future. An increase in short sale volume suggests bearish (negative) sentiment among investors. A decrease on short sale volume suggests bullish (positive) sentiment. How does Syros Pharmaceuticals' short interest compare to its competitors? 0.51% of Syros Pharmaceuticals' shares are currently sold short. Here is how the short interest of companies in the industry of "pharmaceutical products" compare to Syros Pharmaceuticals: Psyence Biomedical Ltd. (2.92%), Spruce Biosciences, Inc. (0.12%), Affimed (4.46%), PainReform Ltd. (7.44%), Jaguar Animal Health, Inc. (2.11%), Aditxt, Inc. (9.34%), Onconetix, Inc. (19.82%), Aspira Women's Health Inc. (1.19%), Alzamend Neuro, Inc. (11.16%), Conduit Pharmaceuticals Inc. (12.19%), Which stocks are the most shorted right now? As of the most recent reporting period, the following stocks had the largest short interest positions: SPDR S&P 500 ETF Trust ($72.10 billion), Invesco QQQ ($26.89 billion), iShares Russell 2000 ETF ($19.61 billion), MicroStrategy Incorporated ($9.52 billion), iShares 20+ Year Treasury Bond ETF ($8.70 billion), WD-40 Company ($7.66 billion), Technology Select Sector SPDR Fund ($6.10 billion), Invesco S&P 500 Equal Weight ETF ($5.80 billion), Invesco S&P 500 Top 50 ETF ($5.53 billion), and Vanguard Large-Cap ETF ($5.35 billion). View all of the most shorted stocks. What does it mean to sell short Syros Pharmaceuticals stock? Short selling SYRS is an investing strategy that aims to generate trading profit from Syros Pharmaceuticals as its price is falling. SYRS shares are trading up $0.00 today. To short a stock, an investor borrows shares, sells them and buys the shares back on the public market later to return it to the lender. Short sellers are betting that a stock will decline in price. If the stock does drop after selling, the short seller buys it back at a lower price and returns it to the lender. The difference between the sell price and the buy price is the trader's profit. How does a short squeeze work against Syros Pharmaceuticals? A short squeeze for Syros Pharmaceuticals occurs when it has a large amount of short interest and its stock appreciates in price. This forces short sellers to cover their short interest positions by buying actual shares of SYRS, which in turn drives the price of the stock up even further. How often is Syros Pharmaceuticals' short interest reported? Short interest is typically published by a stock exchange once per month. However, NASDAQ publishes a report for U.S. stocks, including SYRS, twice per month. The most recent reporting period available is June, 30 2025. 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