Upstream Bio (UPB) Institutional Ownership $8.78 +0.39 (+4.65%) Closing price 04/28/2025 04:00 PM EasternExtended Trading$8.52 -0.26 (-2.96%) As of 04:06 AM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Ownership Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsHeadlinesInsider TradesOwnershipSEC FilingsTrendsBuy This Stock Institutional Ownership Changes (13F Filings) for Upstream Bio (NASDAQ:UPB)Number ofInstitutional Buyers(last 12 months)43TotalInstitutional Inflows(last 12 months)$618.44MNumber ofInstitutional Sellers(last 12 months)1TotalInstitutional Outflows(last 12 months)$20.77K Get UPB Insider Trade Alerts Want to know when executives and insiders are buying or selling Upstream Bio stock? Sign up for InsiderTrades.com's daily newsletter to get the latest insider transactions delivered to your inbox daily. Email Address Skip Chart & View Institutional Buying and Selling Data UPB Institutional Buying and Selling by Quarter Upstream Bio Major Shareholders & Ownership History Export to ExcelReporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails4/8/2025 Rhumbline Advisers13,327$82K0.0%-20.3%0.025% 3/24/2025Wellington Management Group LLP1,583,154$25.63M0.0%N/A2.951% 2/17/2025VR Adviser LLC2,295,319$37.74M2.6%N/A4.282% 2/17/2025Woodline Partners LP526,511$8.66M0.1%N/A0.982% 2/17/2025Sandia Investment Management LP10,000$164K0.4%N/A0.019% 2/17/2025Nuveen Asset Management LLC22,586$371K0.0%N/A0.042% 2/17/2025Orbimed Advisors LLC5,693,589$93.60M2.1%N/A10.622% 2/17/2025MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.9,828$162K0.0%N/A0.018% 2/17/2025Enavate Sciences GP LLC2,459,703$40.44M29.0%N/A4.589% 2/17/2025Deutsche Bank AG14,851$244K0.0%N/A0.028% Get the Latest News and Ratings for UPB and Related StocksEnter your email address below to receive the latest news and analysts' ratings for Upstream Bio and its competitors with MarketBeat's FREE daily newsletter. 2/17/2025Deep Track Capital LP1,000,000$16.44M0.6%N/A1.866% 2/17/2025Balyasny Asset Management L.P.301,152$4.95M0.0%N/A0.562% 2/17/2025Bank of America Corp DE13,963$230K0.0%N/A0.026% 2/17/2025BNP Paribas Financial Markets1,511$25K0.0%N/A0.003% 2/17/2025Alyeska Investment Group L.P.85,000$1.40M0.0%N/A0.159% 2/14/2025Jane Street Group LLC45,549$749K0.0%N/A0.085% 2/14/2025Samsara BioCapital LLC2,217,146$36.45M4.9%N/A4.136% 2/14/2025Soros Fund Management LLC46,350$762K0.0%N/A0.086% 2/14/2025TCG Crossover Management LLC2,801,763$44.86M4.4%N/A5.227% 2/14/2025Nantahala Capital Management LLC600,000$9.86M0.4%N/A1.119% 2/14/2025Northern Trust Corp143,721$2.36M0.0%N/A0.268% 2/14/2025Lynx1 Capital Management LP240,042$3.95M1.5%N/A0.448% 2/14/2025Decheng Capital LLC3,285,293$54.01M11.6%N/A6.129% 2/14/2025Bain Capital Life Sciences Investors LLC2,295,322$37.74M4.4%N/A4.282% 2/14/2025Tower Research Capital LLC TRC 2,846$47K0.0%N/A0.005% 2/14/2025MetLife Investment Management LLC11,034$181K0.0%N/A0.021% 2/13/2025Marshall Wace LLP290,734$4.78M0.0%N/A0.542% 2/13/2025Walleye Capital LLC10,000$164K0.0%N/A0.019% 2/13/2025Barclays PLC27,017$445K0.0%N/A0.050% 2/13/2025Summit Investment Advisors Inc.1,822$30K0.0%N/A0.003% 2/13/2025Legal & General Group Plc1,734$28K0.0%N/A0.003% 2/13/2025Invesco Ltd.15,602$256K0.0%N/A0.029% 2/13/2025FMR LLC7,176,187$117.98M0.0%N/A13.388% 2/13/2025Wells Fargo & Company MN9,047$149K0.0%N/A0.017% 2/12/2025Geode Capital Management LLC363,269$5.97M0.0%N/A0.678% 2/12/2025Alliancebernstein L.P.1,111,337$18.27M0.0%N/A2.073% 2/12/2025Wellington Management Group LLP1,583,154$25.63M0.0%N/A2.954% 2/12/2025Norges Bank1,000,000$16.44M0.0%N/A1.866% 2/12/2025JPMorgan Chase & Co.47,792$786K0.0%N/A0.089% 2/11/2025Corebridge Financial Inc.8,660$142K0.0%N/A0.016% URGENT: Someone's Moving Gold Out of London... (Ad)People who don’t understand the gold market are about to lose a lot of money. Unfortunately, most so-called “gold analysts” have it all wrong… They tell you to invest in gold ETFs - because the popular mining ETFs will someday catch fire and close the price gap with spot gold. Go here to learn about my Top Four picks for the coming bull mania.2/6/2025Charles Schwab Investment Management Inc.135,323$2.23M0.0%N/A0.252% 2/5/2025US Bancorp DE1,660$27K0.0%N/A0.003% 2/4/2025Bank of New York Mellon Corp36,913$607K0.0%N/A0.069% 1/30/2025 Rhumbline Advisers16,721$275K0.0%N/A0.031% 1/23/2025Moody Aldrich Partners LLC74,773$1.23M0.2%N/A0.140% (Data available from 1/1/2016 forward) UPB Institutional Ownership - Frequently Asked Questions Who are the largest shareholders of UPB shares? During the previous two years, 43 institutional investors and hedge funds held shares of Upstream Bio. The most heavily invested institutionals were FMR LLC ($117.98M), Orbimed Advisors LLC ($93.60M), Decheng Capital LLC ($54.01M), TCG Crossover Management LLC ($44.86M), Enavate Sciences GP LLC ($40.44M), VR Adviser LLC ($37.74M), and Bain Capital Life Sciences Investors LLC ($37.74M).Learn more on UPB's institutional investors. Which institutional investors have been buying Upstream Bio stock? Of the 43 institutional investors that purchased Upstream Bio stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: FMR LLC ($7.18M), Orbimed Advisors LLC ($5.69M), Decheng Capital LLC ($3.29M), Wellington Management Group LLP ($3.17M), TCG Crossover Management LLC ($2.80M), Enavate Sciences GP LLC ($2.46M), and Bain Capital Life Sciences Investors LLC ($2.30M). How much institutional buying is happening at Upstream Bio? Institutional investors have bought a total of 37,617,978 shares in the last 24 months. This purchase volume represents approximately $618.44M in transactions. Which Upstream Bio major shareholders have been selling company stock? The following institutional investors have sold Upstream Bio stock in the last 24 months: Rhumbline Advisers ($3.39K). How much institutional selling is happening at Upstream Bio? Institutional investors have sold a total of 3,394 shares in the last 24 months. This volume of shares sold represents approximately $20.77K in transactions. Related Companies VCEL Major Shareholders TWST Major Shareholders SDGR Major Shareholders DNLI Major Shareholders MIRM Major Shareholders TARS Major Shareholders BEAM Major Shareholders NAMS Major Shareholders KYMR Major Shareholders BLTE Major Shareholders This page (NASDAQ:UPB) was last updated on 4/29/2025 by MarketBeat.com Staff From Our PartnersElon Set to Shock the World by May 1st ?Tech legend Jeff Brown recently traveled to the industrial zone of South Memphis to investigate what he believ...Brownstone Research | SponsoredGet Your Bank Account “Fed Invasion” Ready with THESE 4 Simple StepsStarting as soon as a few months from now, the United States government will make a sweeping change to bank ac...Weiss Ratings | SponsoredAltucher: Turn $900 into $108,000 in just 12 months?We are entering the final Trump Bump of our lives. But the biggest returns will not be in the stock market.Paradigm Press | SponsoredCollect $7k per month from Tesla’s SECRET dividendTesla doesn't pay a traditional dividend.... But I just discovered a secret backdoor to collect a secret 69...Investors Alley | SponsoredTrump purposefully forcing markets to crash…Whether you agree with the plan or not doesn’t matter. It’s happening. The only question is – are you re...Porter & Company | SponsoredURGENT: This Altcoin Opportunity Won’t Wait – Act NowMy friends Joel and Adam have a simple motto: "For us, it's always a bull market." That’s because their 92%...Crypto Swap Profits | SponsoredWhy Elon put $51 million into thisWhy Elon Musk Just Invested $51 Million Into Brand New “Miracle Metal” Developed by MIT ScientistsTrue Market Insiders | SponsoredGold Alert: The Truth About Fort Knox Is ComingOwning physical gold isn’t the best way to profit. I’ve found a better way to invest in gold—one that’s alr...Golden Portfolio | Sponsored Adding Choose a watchlist: Watchlist Adding You have already added five stocks to your watchlist. Upgrade to MarketBeat All Access to add more stocks to your watchlist. Adding Upstream Bio, Inc. Please log in to your account or sign up in order to add this asset to your watchlist. Share Upstream Bio With A Colleague Link copied to clipboard. Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Buy UPB Stock Free UPB Stock Alerts