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Upstream Bio (UPB) Institutional Ownership

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$8.94 +0.52 (+6.18%)
Closing price 03/7/2025 04:00 PM Eastern
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$8.94 0.00 (-0.06%)
As of 03/7/2025 05:48 PM Eastern
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Institutional Ownership Changes (13F Filings) for Upstream Bio (NASDAQ:UPB)

Number of
Institutional Buyers
(last 12 months)
43
Total
Institutional Inflows
(last 12 months)
$592.41M
Number of
Institutional Sellers
(last 12 months)
0
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UPB Institutional Buying and Selling by Quarter

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Upstream Bio Major Shareholders & Ownership History

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Reporting DateMajor Shareholder NameShares HeldMarket Value% of PortfolioQuarterly Change in SharesOwnership in CompanyDetails
2/17/2025 VR Adviser LLC2,295,319$37.74M2.6%N/A4.282%
2/17/2025 Woodline Partners LP526,511$8.66M0.1%N/A0.982%
2/17/2025 Sandia Investment Management LP10,000$164K0.4%N/A0.019%
2/17/2025 Nuveen Asset Management LLC22,586$371K0.0%N/A0.042%
2/17/2025 Orbimed Advisors LLC5,693,589$93.60M2.1%N/A10.622%
2/17/2025 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd.9,828$162K0.0%N/A0.018%
2/17/2025 Enavate Sciences GP LLC2,459,703$40.44M29.0%N/A4.589%
2/17/2025 Deutsche Bank AG14,851$244K0.0%N/A0.028%
2/17/2025 Deep Track Capital LP1,000,000$16.44M0.6%N/A1.866%
2/17/2025 Balyasny Asset Management L.P.301,152$4.95M0.0%N/A0.562%
2/17/2025 Bank of America Corp DE13,963$230K0.0%N/A0.026%
2/17/2025 BNP Paribas Financial Markets1,511$25K0.0%N/A0.003%
2/17/2025 Alyeska Investment Group L.P.85,000$1.40M0.0%N/A0.159%
2/14/2025 Jane Street Group LLC45,549$749K0.0%N/A0.085%
2/14/2025 Samsara BioCapital LLC2,217,146$36.45M4.9%N/A4.136%
2/14/2025 Soros Fund Management LLC46,350$762K0.0%N/A0.086%
2/14/2025 TCG Crossover Management LLC2,801,763$44.86M4.4%N/A5.227%
2/14/2025 Nantahala Capital Management LLC600,000$9.86M0.4%N/A1.119%
2/14/2025 Northern Trust Corp143,721$2.36M0.0%N/A0.268%
2/14/2025 Lynx1 Capital Management LP240,042$3.95M1.5%N/A0.448%
2/14/2025 Decheng Capital LLC3,285,293$54.01M11.6%N/A6.129%
2/14/2025 Bain Capital Life Sciences Investors LLC2,295,322$37.74M4.4%N/A4.282%
2/14/2025 Tower Research Capital LLC TRC 2,846$47K0.0%N/A0.005%
2/14/2025 MetLife Investment Management LLC11,034$181K0.0%N/A0.021%
2/13/2025 Marshall Wace LLP290,734$4.78M0.0%N/A0.542%
2/13/2025 Walleye Capital LLC10,000$164K0.0%N/A0.019%
2/13/2025 Barclays PLC27,017$445K0.0%N/A0.050%
2/13/2025 Summit Investment Advisors Inc.1,822$30K0.0%N/A0.003%
2/13/2025 Legal & General Group Plc1,734$28K0.0%N/A0.003%
2/13/2025 Invesco Ltd.15,602$256K0.0%N/A0.029%
2/13/2025 FMR LLC7,176,187$117.98M0.0%N/A13.388%
2/13/2025 Wells Fargo & Company MN9,047$149K0.0%N/A0.017%
2/12/2025 Geode Capital Management LLC363,269$5.97M0.0%N/A0.678%
2/12/2025 Alliancebernstein L.P.1,111,337$18.27M0.0%N/A2.073%
2/12/2025 Wellington Management Group LLP1,583,154$25.63M0.0%N/A2.954%
2/12/2025 Norges Bank1,000,000$16.44M0.0%N/A1.866%
2/12/2025 JPMorgan Chase & Co.47,792$786K0.0%N/A0.089%
2/11/2025 Corebridge Financial Inc.8,660$142K0.0%N/A0.016%
2/6/2025 Charles Schwab Investment Management Inc.135,323$2.23M0.0%N/A0.252%
2/5/2025 US Bancorp DE1,660$27K0.0%N/A0.003%
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2/4/2025 Bank of New York Mellon Corp36,913$607K0.0%N/A0.069%
1/30/2025 Rhumbline Advisers16,721$275K0.0%N/A0.031%
1/23/2025 Moody Aldrich Partners LLC74,773$1.23M0.2%N/A0.140%
(Data available from 1/1/2016 forward)

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UPB Institutional Ownership - Frequently Asked Questions

Who are the largest shareholders of UPB shares?

During the previous two years, 43 institutional investors and hedge funds held shares of Upstream Bio. The most heavily invested institutionals were FMR LLC ($117.98M), Orbimed Advisors LLC ($93.60M), Decheng Capital LLC ($54.01M), TCG Crossover Management LLC ($44.86M), Enavate Sciences GP LLC ($40.44M), VR Adviser LLC ($37.74M), and Bain Capital Life Sciences Investors LLC ($37.74M).Learn more on UPB's institutional investors.

Which institutional investors have been buying Upstream Bio stock?

Of the 43 institutional investors that purchased Upstream Bio stock in the last 24 months, the following investors and hedge funds have bought the highest volume of shares: FMR LLC ($7.18M), Orbimed Advisors LLC ($5.69M), Decheng Capital LLC ($3.29M), TCG Crossover Management LLC ($2.80M), Enavate Sciences GP LLC ($2.46M), Bain Capital Life Sciences Investors LLC ($2.30M), and VR Adviser LLC ($2.30M).

How much institutional buying is happening at Upstream Bio?

Institutional investors have bought a total of 36,034,824 shares in the last 24 months. This purchase volume represents approximately $592.41M in transactions.


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This page (NASDAQ:UPB) was last updated on 3/9/2025 by MarketBeat.com Staff
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