| 11/19/2024 | Barclays PLC | 59,778 | $759K | 0.0% | +409.3% | 0.255% | |
| 11/16/2024 | Geode Capital Management LLC | 455,637 | $5.79M | 0.0% | +8.1% | 1.943% | |
| 11/15/2024 | Barclays PLC | 59,778 | $759K | 0.0% | +409.3% | 0.255% | |
| 11/15/2024 | XTX Topco Ltd | 23,381 | $297K | 0.0% | N/A | 0.100% | |
| 11/15/2024 | Jane Street Group LLC | 30,718 | $390K | 0.0% | -21.1% | 0.131% | |
| 11/15/2024 | Wellington Management Group LLP | 137,300 | $1.74M | 0.0% | -12.0% | 0.586% | |
|
| 11/15/2024 | State Street Corp | 769,583 | $9.77M | 0.0% | +5.9% | 3.282% | |
| 11/15/2024 | RTW Investments LP | 3,787,347 | $48.10M | 0.7% | +6.5% | 16.151% | |
| 11/15/2024 | Point72 Asset Management L.P. | 1,506,646 | $19.13M | 0.0% | -38.5% | 6.425% | |
| 11/15/2024 | Parkman Healthcare Partners LLC | 347,541 | $4.41M | 0.6% | +26.6% | 1.482% | |
| 11/15/2024 | HighVista Strategies LLC | 38,566 | $490K | 0.2% | N/A | 0.164% | |
| 11/14/2024 | Verition Fund Management LLC | 13,254 | $168K | 0.0% | N/A | 0.057% | |
| 11/14/2024 | Vestal Point Capital LP | 400,000 | $5.08M | 0.4% | N/A | 1.705% | |
| 11/14/2024 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 1,341,072 | $17.03M | 0.0% | +1.6% | 5.718% | |
| 11/14/2024 | Stonepine Capital Management LLC | 280,345 | $3.56M | 2.2% | N/A | 1.195% | |
| 11/13/2024 | Great Point Partners LLC | 758,786 | $9.64M | 2.8% | -73.9% | 3.235% | |
| 11/13/2024 | BNP Paribas Financial Markets | 8,546 | $109K | 0.0% | +221.8% | 0.036% | |
| 11/13/2024 | FMR LLC | 23,090 | $293K | 0.0% | +575.1% | 0.098% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 90,493 | $1.15M | 0.0% | +9.1% | 0.386% | |
| 11/9/2024 | Intech Investment Management LLC | 12,203 | $155K | 0.0% | N/A | 0.052% | |
| 11/5/2024 | GSA Capital Partners LLP | 19,597 | $249K | 0.0% | N/A | 0.084% | |
| 10/31/2024 | ARK Investment Management LLC | 121,634 | $1.55M | 0.0% | -19.9% | 0.519% | |
| 10/28/2024 | Oak Ridge Investments LLC | 76,799 | $975K | 0.1% | -3.9% | 0.327% | |
| 10/28/2024 | Rice Hall James & Associates LLC | 271,897 | $3.45M | 0.2% | +273.6% | 1.159% | |
| 10/25/2024 | China Universal Asset Management Co. Ltd. | 8,100 | $103K | 0.0% | +90.9% | 0.035% | |
| 10/11/2024 | Wesbanco Bank Inc. | 74,400 | $945K | 0.0% | N/A | 0.317% | |
| 10/3/2024 | SG Americas Securities LLC | 14,062 | $179K | 0.0% | N/A | 0.060% | |
| 8/16/2024 | Coastal Bridge Advisors LLC | 38,500 | $646K | 0.2% | +4.1% | 0.164% | |
| 8/16/2024 | Annandale Capital LLC | 75,552 | $1.27M | 0.2% | -7.4% | 0.322% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 13,302 | $223K | 0.0% | -59.1% | 0.057% | |
| 8/15/2024 | Millennium Management LLC | 1,160,899 | $19.48M | 0.0% | +2,672.0% | 4.951% | |
| 8/15/2024 | AQR Capital Management LLC | 30,290 | $508K | 0.0% | -28.3% | 0.129% | |
| 8/14/2024 | Point72 Asset Management L.P. | 2,449,277 | $41.10M | 0.1% | +120.3% | 10.445% | |
| 8/14/2024 | Cubist Systematic Strategies LLC | 44,949 | $754K | 0.0% | +630.9% | 0.192% | |
| 8/14/2024 | Great Point Partners LLC | 2,906,259 | $48.77M | 9.3% | +10.9% | 12.393% | |
| 8/14/2024 | Marshall Wace LLP | 42,841 | $719K | 0.0% | N/A | 0.183% | |
| 8/14/2024 | ProShare Advisors LLC | 11,888 | $199K | 0.0% | N/A | 0.051% | |
| 8/8/2024 | Main Street Financial Solutions LLC | 24,000 | $403K | 0.0% | N/A | 0.102% | |
| 8/8/2024 | Rice Hall James & Associates LLC | 72,787 | $1.22M | 0.1% | +3.4% | 0.310% | |
| 8/7/2024 | Cowen AND Company LLC | 2,099,482 | $35.23M | 1.0% | +29.1% | 8.953% | |
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| 8/1/2024 | Rhumbline Advisers | 50,477 | $847K | 0.0% | +37.2% | 0.215% | |
| 7/26/2024 | ARK Investment Management LLC | 151,781 | $2.55M | 0.0% | +3.7% | 0.647% | |
| 7/26/2024 | Bank of New York Mellon Corp | 96,619 | $1.62M | 0.0% | +41.6% | 0.412% | |
| 7/22/2024 | Harel Insurance Investments & Financial Services Ltd. | 463,565 | $7.78M | 0.1% | -31.2% | 1.977% | |
| 7/17/2024 | Oak Ridge Investments LLC | 79,929 | $1.34M | 0.1% | +30.6% | 0.341% | |
| 7/16/2024 | Shikiar Asset Management Inc. | 10,750 | $180K | 0.0% | -67.7% | 0.046% | |
| 5/29/2024 | Opaleye Management Inc. | 270,000 | $4.05M | 0.9% | -15.6% | 1.151% | |
| 5/17/2024 | Tidal Investments LLC | 28,320 | $425K | 0.0% | N/A | 0.121% | |
| 5/16/2024 | California State Teachers Retirement System | 2,788 | $42K | 0.0% | -37.7% | 0.012% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 267,143 | $4.01M | 0.0% | N/A | 1.139% | |
| 5/10/2024 | Vanguard Group Inc. | 194,966 | $2.92M | 0.0% | +14.3% | 0.831% | |
| 5/1/2024 | BNP Paribas Financial Markets | 39,795 | $597K | 0.0% | +73.1% | 0.170% | |
| 5/1/2024 | Oak Ridge Investments LLC | 61,204 | $918K | 0.1% | N/A | 0.261% | |
| 4/30/2024 | Harel Insurance Investments & Financial Services Ltd. | 673,487 | $10.10M | 0.2% | -22.6% | 2.872% | |
| 4/29/2024 | China Universal Asset Management Co. Ltd. | 5,903 | $89K | 0.0% | +65.1% | 0.025% | |
| 3/5/2024 | Wellington Management Group LLP | 104,600 | $1.57M | 0.0% | +49.3% | 0.446% | |
| 2/22/2024 | Sierra Summit Advisors LLC | 14,515 | $218K | 0.1% | N/A | 0.062% | |
| 2/15/2024 | Parkman Healthcare Partners LLC | 175,500 | $2.63M | 0.4% | +20.8% | 0.748% | |
| 2/14/2024 | Superstring Capital Management LP | 255,430 | $3.83M | 2.7% | N/A | 1.089% | |
| 2/14/2024 | RTW Investments LP | 1,726,808 | $25.90M | 0.4% | +101.4% | 7.364% | |
| 2/13/2024 | Tower Research Capital LLC TRC | 1,691 | $25K | 0.0% | -83.7% | 0.007% | |
| 2/7/2024 | Jump Financial LLC | 33,320 | $500K | 0.0% | +12.6% | 0.142% | |
| 2/7/2024 | BNP Paribas Financial Markets | 22,996 | $345K | 0.0% | +40.4% | 0.098% | |
| 1/31/2024 | Federated Hermes Inc. | 11,709 | $176K | 0.0% | -10.8% | 0.050% | |
| 1/26/2024 | Cerity Partners LLC | 125,226 | $1.88M | 0.0% | N/A | 0.534% | |
| 1/25/2024 | Allspring Global Investments Holdings LLC | 4,955 | $74K | 0.0% | +31.6% | 0.021% | |
| 1/24/2024 | China Universal Asset Management Co. Ltd. | 3,575 | $54K | 0.0% | +361.9% | 0.015% | |
| 1/17/2024 | ARK Investment Management LLC | 161,525 | $2.42M | 0.0% | -25.0% | 0.689% | |
| 1/12/2024 | SG Americas Securities LLC | 8,707 | $131K | 0.0% | N/A | 0.037% | |
| 11/15/2023 | Annandale Capital LLC | 81,831 | $1.15M | 0.3% | -3.0% | 0.349% | |
| 11/15/2023 | RA Capital Management L.P. | 1,483,697 | $20.79M | 0.4% | N/A | 6.327% | |
| 11/15/2023 | Laurion Capital Management LP | 380,600 | $5.33M | 0.0% | +3.1% | 1.623% | |
| 11/14/2023 | Schonfeld Strategic Advisors LLC | 130,200 | $1.82M | 0.0% | N/A | 0.555% | |
| 11/13/2023 | Connor Clark & Lunn Investment Management Ltd. | 29,766 | $417K | 0.0% | +38.4% | 0.127% | |
| 11/13/2023 | EAM Investors LLC | 170,523 | $2.39M | 0.5% | N/A | 0.727% | |
| 11/13/2023 | Federated Hermes Inc. | 13,130 | $184K | 0.0% | N/A | 0.056% | |
| 11/13/2023 | Acadian Asset Management LLC | 4,563 | $63K | 0.0% | -36.5% | 0.019% | |
| 11/13/2023 | Silverarc Capital Management LLC | 508,883 | $7.13M | 2.2% | N/A | 2.170% | |
| 11/7/2023 | Jump Financial LLC | 29,600 | $415K | 0.0% | N/A | 0.126% | |
| 11/6/2023 | Clal Insurance Enterprises Holdings Ltd | 222,159 | $3.11M | 0.0% | -58.0% | 0.947% | |
| 11/2/2023 | Rice Hall James & Associates LLC | 75,180 | $1.05M | 0.1% | -1.2% | 0.321% | |
| 10/30/2023 | Harel Insurance Investments & Financial Services Ltd. | 870,194 | $12.19M | 0.2% | -15.1% | 3.711% | |
| 10/30/2023 | Meitav Investment House Ltd. | 91,456 | $1.30M | 0.0% | -13.3% | 0.390% | |
| 10/27/2023 | Allspring Global Investments Holdings LLC | 3,764 | $53K | 0.0% | N/A | 0.016% | |
| 10/25/2023 | Migdal Insurance & Financial Holdings Ltd. | 648,302 | $9.08M | 0.2% | -7.2% | 2.765% | |
| 10/24/2023 | Bank of New York Mellon Corp | 57,806 | $810K | 0.0% | +25.9% | 0.247% | |
| 10/20/2023 | Denali Advisors LLC | 14,300 | $200K | 0.1% | -24.7% | 0.061% | |
| 10/18/2023 | ARK Investment Management LLC | 215,272 | $3.02M | 0.0% | +6.6% | 0.918% | |
| 9/21/2023 | Barclays PLC | 3,901 | $41K | 0.0% | -52.1% | 0.017% | |
| 8/17/2023 | Coastal Bridge Advisors LLC | 37,732 | $391K | 0.1% | +2.0% | 0.161% | |
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| 8/16/2023 | Stonepine Capital Management LLC | 448,508 | $4.64M | 1.7% | -36.1% | 1.913% | |
| 8/14/2023 | Vivaldi Capital Management LP | 11,500 | $119K | 0.0% | N/A | 0.049% | |
| 8/14/2023 | Partners Capital Investment Group LLP | 15,384 | $159K | 0.0% | N/A | 0.066% | |
| 8/11/2023 | Stonepine Capital Management LLC | 448,508 | $4.64M | 1.7% | -36.1% | 1.972% | |
| 8/10/2023 | Meitav Investment House Ltd. | 105,512 | $1.11M | 0.0% | -1.6% | 0.464% | |
| 8/8/2023 | AlphaCentric Advisors LLC | 152,500 | $1.58M | 0.9% | N/A | 0.671% | |
| 8/7/2023 | Acadian Asset Management LLC | 7,187 | $74K | 0.0% | +57.5% | 0.032% | |
| 8/4/2023 | American International Group Inc. | 9,417 | $97K | 0.0% | N/A | 0.041% | |
| 7/31/2023 | Menora Mivtachim Holdings LTD. | 2,529,820 | $26.18M | 0.2% | -13.3% | 11.125% | |
| 7/24/2023 | Rice Hall James & Associates LLC | 76,087 | $788K | 0.0% | +3.9% | 0.335% | |
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