Vertex Pharmaceuticals (VRTX) Competitors $495.83 +11.61 (+2.40%) As of 04/14/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock VRTX vs. AMGN, GILD, REGN, ALNY, BIIB, UTHR, INCY, BMRN, EXEL, and NBIXShould you be buying Vertex Pharmaceuticals stock or one of its competitors? The main competitors of Vertex Pharmaceuticals include Amgen (AMGN), Gilead Sciences (GILD), Regeneron Pharmaceuticals (REGN), Alnylam Pharmaceuticals (ALNY), Biogen (BIIB), United Therapeutics (UTHR), Incyte (INCY), BioMarin Pharmaceutical (BMRN), Exelixis (EXEL), and Neurocrine Biosciences (NBIX). These companies are all part of the "biotechnology" industry. Vertex Pharmaceuticals vs. Amgen Gilead Sciences Regeneron Pharmaceuticals Alnylam Pharmaceuticals Biogen United Therapeutics Incyte BioMarin Pharmaceutical Exelixis Neurocrine Biosciences Amgen (NASDAQ:AMGN) and Vertex Pharmaceuticals (NASDAQ:VRTX) are both large-cap medical companies, but which is the superior stock? We will compare the two companies based on the strength of their risk, community ranking, valuation, analyst recommendations, earnings, media sentiment, profitability, institutional ownership and dividends. Which has higher valuation & earnings, AMGN or VRTX? Amgen has higher revenue and earnings than Vertex Pharmaceuticals. Vertex Pharmaceuticals is trading at a lower price-to-earnings ratio than Amgen, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAmgen$33.42B4.73$4.09B$7.5538.93Vertex Pharmaceuticals$11.02B11.55-$535.60M-$2.20-225.38 Do analysts prefer AMGN or VRTX? Amgen currently has a consensus price target of $314.91, indicating a potential upside of 7.14%. Vertex Pharmaceuticals has a consensus price target of $512.41, indicating a potential upside of 3.34%. Given Amgen's higher probable upside, equities analysts clearly believe Amgen is more favorable than Vertex Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Amgen 2 Sell rating(s) 9 Hold rating(s) 11 Buy rating(s) 1 Strong Buy rating(s) 2.48Vertex Pharmaceuticals 0 Sell rating(s) 10 Hold rating(s) 14 Buy rating(s) 1 Strong Buy rating(s) 2.64 Do insiders & institutionals believe in AMGN or VRTX? 76.5% of Amgen shares are held by institutional investors. Comparatively, 91.0% of Vertex Pharmaceuticals shares are held by institutional investors. 0.7% of Amgen shares are held by company insiders. Comparatively, 0.2% of Vertex Pharmaceuticals shares are held by company insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company will outperform the market over the long term. Is AMGN or VRTX more profitable? Amgen has a net margin of 12.24% compared to Vertex Pharmaceuticals' net margin of -4.86%. Amgen's return on equity of 176.32% beat Vertex Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Amgen12.24% 176.32% 11.71% Vertex Pharmaceuticals -4.86%-2.02%-1.49% Which has more risk & volatility, AMGN or VRTX? Amgen has a beta of 0.59, meaning that its stock price is 41% less volatile than the S&P 500. Comparatively, Vertex Pharmaceuticals has a beta of 0.5, meaning that its stock price is 50% less volatile than the S&P 500. Does the media prefer AMGN or VRTX? In the previous week, Amgen had 20 more articles in the media than Vertex Pharmaceuticals. MarketBeat recorded 75 mentions for Amgen and 55 mentions for Vertex Pharmaceuticals. Vertex Pharmaceuticals' average media sentiment score of 1.29 beat Amgen's score of 0.97 indicating that Vertex Pharmaceuticals is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Amgen 47 Very Positive mention(s) 2 Positive mention(s) 11 Neutral mention(s) 11 Negative mention(s) 1 Very Negative mention(s) Positive Vertex Pharmaceuticals 38 Very Positive mention(s) 3 Positive mention(s) 8 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Does the MarketBeat Community favor AMGN or VRTX? Vertex Pharmaceuticals received 50 more outperform votes than Amgen when rated by MarketBeat users. Likewise, 75.01% of users gave Vertex Pharmaceuticals an outperform vote while only 71.83% of users gave Amgen an outperform vote. CompanyUnderperformOutperformAmgenOutperform Votes155371.83% Underperform Votes60928.17% Vertex PharmaceuticalsOutperform Votes160375.01% Underperform Votes53424.99% SummaryAmgen beats Vertex Pharmaceuticals on 11 of the 18 factors compared between the two stocks. Remove Ads Get Vertex Pharmaceuticals News Delivered to You Automatically Sign up to receive the latest news and ratings for VRTX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding {thisCompany.Symbol} and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart VRTX vs. The Competition Export to ExcelMetricVertex PharmaceuticalsPharmaceutical IndustryMedical SectorNASDAQ ExchangeMarket Cap$127.32B$6.35B$5.35B$7.58BDividend YieldN/A3.23%5.11%4.33%P/E Ratio-225.386.7721.6517.79Price / Sales11.55228.59376.3294.47Price / CashN/A65.6738.1534.64Price / Book7.765.886.443.99Net Income-$535.60M$141.32M$3.20B$247.24M7 Day Performance4.48%5.18%6.67%5.84%1 Month Performance-1.77%-12.93%-6.27%-5.78%1 Year Performance25.04%-14.85%8.56%-1.99% Vertex Pharmaceuticals Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)VRTXVertex Pharmaceuticals4.0984 of 5 stars$495.83+2.4%$512.41+3.3%+25.0%$127.32B$11.02B-225.386,100Short Interest ↓Analyst RevisionPositive NewsAMGNAmgen4.1879 of 5 stars$291.59-1.0%$314.04+7.7%+10.0%$156.74B$33.42B38.6428,000Analyst ForecastNews CoverageGILDGilead Sciences4.5372 of 5 stars$106.10-1.1%$105.12-0.9%+56.5%$132.11B$28.75B286.7517,000Positive NewsREGNRegeneron Pharmaceuticals4.8477 of 5 stars$573.94+0.1%$966.88+68.5%-36.9%$62.98B$14.20B15.0511,900Analyst ForecastPositive NewsALNYAlnylam Pharmaceuticals4.5026 of 5 stars$233.77-0.8%$316.25+35.3%+61.6%$30.41B$2.25B-107.732,000Analyst ForecastBIIBBiogen4.6491 of 5 stars$119.72-2.7%$213.33+78.2%-39.8%$17.54B$9.68B10.718,720UTHRUnited Therapeutics4.9041 of 5 stars$290.09-0.8%$388.25+33.8%+22.2%$13.03B$2.88B12.74980Positive NewsINCYIncyte4.798 of 5 stars$60.37-0.3%$74.88+24.0%+10.0%$11.70B$4.24B223.882,320BMRNBioMarin Pharmaceutical4.8659 of 5 stars$58.80-2.4%$94.00+59.9%-35.3%$11.25B$2.85B26.813,401Gap UpEXELExelixis4.256 of 5 stars$34.78+0.6%$37.59+8.1%+56.7%$9.74B$2.17B19.661,220Positive NewsGap DownNBIXNeurocrine Biosciences4.8385 of 5 stars$92.75-3.0%$163.52+76.3%-29.5%$9.23B$2.36B28.151,200Analyst UpgradeNews CoveragePositive NewsGap Up Remove Ads Related Companies and Tools Related Companies Amgen Alternatives Gilead Sciences Alternatives Regeneron Pharmaceuticals Alternatives Alnylam Pharmaceuticals Alternatives Biogen Alternatives United Therapeutics Alternatives Incyte Alternatives BioMarin Pharmaceutical Alternatives Exelixis Alternatives Neurocrine Biosciences Alternatives Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:VRTX) was last updated on 4/15/2025 by MarketBeat.com Staff From Our PartnersGet Your Bank Account “Fed Invasion” Ready with THESE 4 Simple StepsStarting as soon as a few months from now, the United States government will make a sweeping change to bank ac...Weiss Ratings | SponsoredElon Musk Confirms: Tesla’s Optimus is Replacing Workers… and Heading to MarsElon Musk just confirmed Tesla’s robot will go to Mars. 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