NYSE:ANRO Alto Neuroscience (ANRO) Stock Price, News & Analysis $2.42 -0.09 (-3.40%) Closing price 03:59 PM EasternExtended Trading$2.43 +0.02 (+0.66%) As of 06:25 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Stock Analysis Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFinancialsHeadlinesInsider TradesOwnershipSEC FilingsShort InterestTrendsBuy This Stock About Alto Neuroscience Stock (NYSE:ANRO) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get Alto Neuroscience alerts:Sign Up Key Stats Today's Range$2.37▼$2.5550-Day Range$2.51▼$4.8452-Week Range$2.37▼$17.55Volume222,481 shsAverage Volume359,579 shsMarket Capitalization$65.13 millionP/E RatioN/ADividend YieldN/APrice Target$16.75Consensus RatingModerate Buy Company OverviewAlto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. Its product pipeline comprising ALTO-100, which is in phase 2b clinical trial for the treatment of patients with major depressive disorder (MDD); and which is in phase 2a clinical trial for the treatment of post-traumatic stress disorder. The company develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties which is in phase 2b clinical trial to treat patients with MDD; ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor which is in phase 1 clinical trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist which is in phase 1 clinical trial to treat patients with MDD and higher levels of anhedonia; and ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor which is in phase 1 clinical trial for the treatment of MDD. In addition, it develops novel pharmacodynamically synergistic combination and biomarker platform that collects patient-specific data to identify biomarker-characterized patient. The company was incorporated in 2019 and is headquartered in Los Altos, California.Read More… Remove Ads Alto Neuroscience Stock Analysis - MarketRank™See Top-Rated MarketRank™ Stocks35th Percentile Overall ScoreANRO MarketRank™: Alto Neuroscience scored higher than 35% of companies evaluated by MarketBeat, and ranked 782nd out of 941 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation. Analyst's Opinion3.3 / 5Analyst RatingModerate Buy Consensus RatingAlto Neuroscience has received a consensus rating of Moderate Buy. The company's average rating score is 2.50, and is based on 3 buy ratings, 3 hold ratings, and no sell ratings.Amount of Analyst CoverageAlto Neuroscience has only been the subject of 1 research reports in the past 90 days.Read more about Alto Neuroscience's stock forecast and price target. Earnings and Valuation0.6 / 5Proj. Earnings GrowthGrowing Earnings GrowthEarnings for Alto Neuroscience are expected to grow in the coming year, from ($2.54) to ($2.39) per share.Price to Earnings Ratio vs. the MarketThe P/E ratio of Alto Neuroscience is -0.95, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Price to Earnings Ratio vs. SectorThe P/E ratio of Alto Neuroscience is -0.95, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.Read more about Alto Neuroscience's valuation and earnings. Short Interest0.0 / 5Short Interest LevelBearish Percentage of Shares Shorted16.26% of the float of Alto Neuroscience has been sold short.Short Interest Ratio / Days to CoverAlto Neuroscience has a short interest ratio ("days to cover") of 12.4, which indicates bearish sentiment.Change versus previous monthShort interest in Alto Neuroscience has recently increased by 1.08%, indicating that investor sentiment is decreasing. Dividend0.0 / 5Dividend StrengthN/A Dividend YieldAlto Neuroscience does not currently pay a dividend.Dividend GrowthAlto Neuroscience does not have a long track record of dividend growth. Sustainability and ESGN/AEnvironmental ScoreN/A Percentage of Shares Shorted16.26% of the float of Alto Neuroscience has been sold short.Short Interest Ratio / Days to CoverAlto Neuroscience has a short interest ratio ("days to cover") of 12.4, which indicates bearish sentiment.Change versus previous monthShort interest in Alto Neuroscience has recently increased by 1.08%, indicating that investor sentiment is decreasing. News and Social Media3.2 / 5News Sentiment0.79 News SentimentAlto Neuroscience has a news sentiment score of 0.79. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This news sentiment score is similar to the average news sentiment of Medical companies.News Coverage This WeekMarketBeat has tracked 20 news articles for Alto Neuroscience this week, compared to 2 articles on an average week.Search Interest10 people have searched for ANRO on MarketBeat in the last 30 days. This is an increase of 233% compared to the previous 30 days.MarketBeat Follows2 people have added Alto Neuroscience to their MarketBeat watchlist in the last 30 days. Company OwnershipN/AInsider TradingN/A Insider Buying vs. Insider SellingIn the past three months, Alto Neuroscience insiders have not sold or bought any company stock.Read more about Alto Neuroscience's insider trading history. Receive ANRO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for Alto Neuroscience and its competitors with MarketBeat's FREE daily newsletter. Email Address ANRO Stock News HeadlinesJonesTrading Sticks to Its Buy Rating for Alto Neuroscience, Inc. (ANRO)March 25 at 3:11 AM | markets.businessinsider.comAnalysts Set Expectations for ANRO Q1 EarningsMarch 25 at 2:25 AM | americanbankingnews.comStop working weekends (do this 2-minute trick instead)Since the pandemic, the average mortgage payment has jumped from $1,427 to $2,047. That's an extra $600 every single month just vanishing from people's pockets. Meanwhile, credit card debt is hitting record highs, and savings accounts are at their lowest since 2008. Most folks are left with two options… Get a second job... or work overtime on weekends. But what if there was a third option? I just uncovered a shocking anomaly in the options market that could change everything... One that lets you target extra cash on days when most people make nothing - weekends. Think what that could mean for your monthly budget...March 27, 2025 | WealthPress (Ad)Buy Rating Reaffirmed for Alto Neuroscience, Inc. Amid Promising Pipeline and Upcoming Data ReadoutsMarch 24 at 11:13 AM | tipranks.comBrokerages Set Alto Neuroscience, Inc. (NYSE:ANRO) PT at $16.75March 24 at 1:07 AM | americanbankingnews.comWilliam Blair Reiterates "Outperform" Rating for Alto Neuroscience (NYSE:ANRO)March 23, 2025 | americanbankingnews.comAnalysts Offer Insights on NA Companies: Reddit Inc Class A (RDDT) and Alto Neuroscience, Inc. (ANRO)March 22, 2025 | markets.businessinsider.comALTO NEUROSCIENCE Earnings Results: $ANRO Reports Quarterly EarningsMarch 22, 2025 | nasdaq.comSee More Headlines ANRO Stock Analysis - Frequently Asked Questions How have ANRO shares performed this year? Alto Neuroscience's stock was trading at $4.23 at the beginning of 2025. Since then, ANRO stock has decreased by 42.9% and is now trading at $2.4150. View the best growth stocks for 2025 here. How were Alto Neuroscience's earnings last quarter? Alto Neuroscience, Inc. (NYSE:ANRO) issued its quarterly earnings results on Thursday, March, 20th. The company reported ($0.56) EPS for the quarter, topping analysts' consensus estimates of ($0.65) by $0.09. When did Alto Neuroscience IPO? Alto Neuroscience (ANRO) raised $129 million in an IPO on Friday, February 2nd 2024. The company issued 8,040,000 shares at a price of $16.00 per share. Who are Alto Neuroscience's major shareholders? Top institutional investors of Alto Neuroscience include Point72 Asset Management L.P. (6.27%), Franklin Resources Inc. (4.31%), Vestal Point Capital LP (3.39%) and Price T Rowe Associates Inc. MD (3.13%). Insiders that own company stock include Wave Global Lp Alpha, Adam Savitz and Nicholas Conrad Smith. View institutional ownership trends. How do I buy shares of Alto Neuroscience? Shares of ANRO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of Alto Neuroscience own? Based on aggregate information from My MarketBeat watchlists, some other companies that Alto Neuroscience investors own include JPMorgan Chase & Co. (JPM), Tesla (TSLA), Meta Platforms (META), NVIDIA (NVDA), Advanced Micro Devices (AMD), Netflix (NFLX) and Alphabet (GOOG). Company Calendar Last Earnings3/20/2025Today3/27/2025Next Earnings (Estimated)5/13/2025Fiscal Year End12/31/2025Get Stock AlertsIndustry, Sector and Symbol Stock ExchangeNYSE SectorMedical Industry Pharmaceutical preparations Sub-IndustryPharmaceutical Products Current SymbolNYSE:ANRO Previous SymbolNYSE:ANRO CIK1999480 Webwww.altoneuroscience.com Phone(650) 200-0412FaxN/AEmployeesN/AYear FoundedN/APrice Target and Rating Average Stock Price Target$16.75 High Stock Price Target$43.00 Low Stock Price Target$4.00 Potential Upside/Downside+597.9%Consensus RatingModerate Buy Rating Score (0-4)2.50 Research Coverage6 Analysts Profitability EPS (Most Recent Fiscal Year)($2.54) Trailing P/E RatioN/A Forward P/E RatioN/A P/E GrowthN/ANet Income$-36,310,000.00 Net MarginsN/A Pretax MarginN/A Return on Equity-49.28% Return on Assets-33.52% Debt Debt-to-Equity Ratio0.05 Current Ratio13.10 Quick Ratio13.09 Sales & Book Value Annual SalesN/A Price / SalesN/A Cash FlowN/A Price / Cash FlowN/A Book ValueN/A Price / BookN/AMiscellaneous Outstanding Shares26,970,000Free FloatN/AMarket Cap$64.73 million OptionableN/A BetaN/A Reduce the RiskMarket downturns give many investors pause, and for good reason. 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