Milestone Scientific, Inc., listed on the New York Stock Exchange under the symbol MLSS, is a medical device company specializing in the development and commercialization of computer-controlled injection technologies for local anesthesia and pain management. The company’s proprietary systems are designed to enhance patient comfort, improve clinical outcomes and streamline the administration of anesthetics in dental and medical procedures. Through its precision delivery platforms, Milestone Scientific aims to set a new standard for minimally invasive injections.
At the core of Milestone Scientific’s product portfolio is the Single Tooth Anesthesia (STA) System, which uses Comunication Controlled Local Anesthetic Delivery (CCLAD) technology to provide targeted, atraumatic anesthesia for individual dental roots. Complementing STA is the CompuFlo® Epidural System, which employs real-time pressure sensing to identify tissue planes and facilitate safer, more accurate epidural needle placement. Both systems are supported by a growing body of clinical research, patents and peer-reviewed publications that underscore their efficacy and safety.
Milestone Scientific distributes its technologies through a combination of direct sales and partnerships with dental and medical distributors, serving markets across North America, Europe, Latin America and parts of Asia. The company maintains strategic relationships with dental institutions, hospitals and specialty clinics to drive adoption and training. In addition to product sales, Milestone offers continuing education programs for clinicians, ensuring that users are proficient in device operation and best practices for pain management.
Founded in 1995 and headquartered in Livingston, New Jersey, Milestone Scientific was established to bridge the gap between conventional syringe techniques and modern computer-aided delivery systems. The company’s leadership team brings together experience in medical device development, regulatory affairs and commercial strategy to support global expansion and ongoing innovation. Through sustained investment in research and development, Milestone Scientific continues to advance its platform technologies and explore new applications in both dental and medical markets.
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