Free Trial

Zymeworks (ZYME) Competitors

Zymeworks logo
$12.84 -0.06 (-0.43%)
Closing price 07/3/2025 01:45 PM Eastern
Extended Trading
$12.84 0.00 (0.00%)
As of 07/3/2025 04:19 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

ZYME vs. PTGX, AAPG, SRRK, MTSR, KYMR, VKTX, MOR, CRNX, ALVO, and MLTX

Should you be buying Zymeworks stock or one of its competitors? The main competitors of Zymeworks include Protagonist Therapeutics (PTGX), Ascentage Pharma Group International (AAPG), Scholar Rock (SRRK), Metsera (MTSR), Kymera Therapeutics (KYMR), Viking Therapeutics (VKTX), MorphoSys (MOR), Crinetics Pharmaceuticals (CRNX), Alvotech (ALVO), and MoonLake Immunotherapeutics (MLTX). These companies are all part of the "pharmaceutical products" industry.

Zymeworks vs. Its Competitors

Protagonist Therapeutics (NASDAQ:PTGX) and Zymeworks (NYSE:ZYME) are both medical companies, but which is the better business? We will contrast the two companies based on the strength of their media sentiment, risk, profitability, earnings, dividends, analyst recommendations, valuation and institutional ownership.

98.6% of Protagonist Therapeutics shares are owned by institutional investors. Comparatively, 92.9% of Zymeworks shares are owned by institutional investors. 4.9% of Protagonist Therapeutics shares are owned by insiders. Comparatively, 1.9% of Zymeworks shares are owned by insiders. Strong institutional ownership is an indication that hedge funds, endowments and large money managers believe a company will outperform the market over the long term.

Protagonist Therapeutics has higher revenue and earnings than Zymeworks. Zymeworks is trading at a lower price-to-earnings ratio than Protagonist Therapeutics, indicating that it is currently the more affordable of the two stocks.

CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings Ratio
Protagonist Therapeutics$434.43M7.30$275.19M$0.7568.27
Zymeworks$93.38M9.56-$118.67M-$1.49-8.61

In the previous week, Protagonist Therapeutics had 2 more articles in the media than Zymeworks. MarketBeat recorded 5 mentions for Protagonist Therapeutics and 3 mentions for Zymeworks. Protagonist Therapeutics' average media sentiment score of 0.54 beat Zymeworks' score of 0.20 indicating that Protagonist Therapeutics is being referred to more favorably in the media.

Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment
Protagonist Therapeutics
2 Very Positive mention(s)
0 Positive mention(s)
3 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Positive
Zymeworks
0 Very Positive mention(s)
1 Positive mention(s)
1 Neutral mention(s)
0 Negative mention(s)
0 Very Negative mention(s)
Neutral

Protagonist Therapeutics has a beta of 2.26, suggesting that its stock price is 126% more volatile than the S&P 500. Comparatively, Zymeworks has a beta of 1.17, suggesting that its stock price is 17% more volatile than the S&P 500.

Protagonist Therapeutics has a net margin of 27.04% compared to Zymeworks' net margin of -182.75%. Protagonist Therapeutics' return on equity of 9.22% beat Zymeworks' return on equity.

Company Net Margins Return on Equity Return on Assets
Protagonist Therapeutics27.04% 9.22% 8.31%
Zymeworks -182.75%-23.00%-18.04%

Protagonist Therapeutics currently has a consensus price target of $66.10, indicating a potential upside of 29.10%. Zymeworks has a consensus price target of $21.00, indicating a potential upside of 63.62%. Given Zymeworks' higher probable upside, analysts clearly believe Zymeworks is more favorable than Protagonist Therapeutics.

Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Protagonist Therapeutics
0 Sell rating(s)
1 Hold rating(s)
8 Buy rating(s)
1 Strong Buy rating(s)
3.00
Zymeworks
0 Sell rating(s)
2 Hold rating(s)
7 Buy rating(s)
1 Strong Buy rating(s)
2.90

Summary

Protagonist Therapeutics beats Zymeworks on 14 of the 16 factors compared between the two stocks.

Get Zymeworks News Delivered to You Automatically

Sign up to receive the latest news and ratings for ZYME and its competitors with MarketBeat's FREE daily newsletter.

New MarketBeat Followers Over Time

This chart shows the number of new MarketBeat users adding ZYME and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period.
Skip Chart

Media Sentiment Over Time

This chart shows the average media sentiment of NYSE and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.
Skip Chart

ZYME vs. The Competition

MetricZymeworksPharmaceutical IndustryMedical SectorNYSE Exchange
Market Cap$893.02M$839.46M$5.56B$20.72B
Dividend YieldN/A4.84%5.24%3.72%
P/E Ratio-8.561.1527.6128.07
Price / Sales9.56228.55417.3038.44
Price / CashN/A23.4436.8922.53
Price / Book1.946.328.034.58
Net Income-$118.67M-$27.99M$3.18B$985.54M
7 Day Performance2.93%2.11%2.93%2.79%
1 Month Performance5.81%10.13%3.75%5.46%
1 Year Performance44.54%11.60%35.20%15.06%

Zymeworks Competitors List

CompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)
ZYME
Zymeworks
1.9953 of 5 stars
$12.84
-0.4%
$21.00
+63.6%
+53.0%$893.02M$93.38M-8.56460Analyst Forecast
PTGX
Protagonist Therapeutics
2.1068 of 5 stars
$53.36
+0.0%
$66.10
+23.9%
+48.4%$3.31B$434.43M71.15120
AAPG
Ascentage Pharma Group International
N/A$37.15
-0.6%
N/AN/A$3.26B$134.35M0.00600Gap Up
SRRK
Scholar Rock
3.339 of 5 stars
$33.28
-2.2%
$42.67
+28.2%
+355.0%$3.23B$33.19M-13.15140
MTSR
Metsera
N/A$29.00
-2.0%
$55.00
+89.7%
N/A$3.11BN/A0.0081Gap Down
KYMR
Kymera Therapeutics
3.1711 of 5 stars
$46.29
+0.9%
$59.82
+29.2%
+48.6%$2.99B$47.07M-14.93170Positive News
Analyst Forecast
Insider Trade
VKTX
Viking Therapeutics
4.3571 of 5 stars
$24.86
-4.4%
$87.15
+250.6%
-44.2%$2.92BN/A-21.6220Trending News
Insider Trade
MOR
MorphoSys
N/A$18.96
flat
N/AN/A$2.86B$238.28M-5.45730News Coverage
CRNX
Crinetics Pharmaceuticals
3.3052 of 5 stars
$29.91
-0.8%
$74.56
+149.3%
-32.4%$2.82B$1.04M-7.83210
ALVO
Alvotech
3.5282 of 5 stars
$9.13
-2.4%
$18.00
+97.2%
-24.4%$2.82B$491.98M24.681,032
MLTX
MoonLake Immunotherapeutics
2.1639 of 5 stars
$44.87
+3.1%
$78.71
+75.4%
+9.9%$2.78BN/A-19.512News Coverage

Related Companies and Tools


This page (NYSE:ZYME) was last updated on 7/5/2025 by MarketBeat.com Staff
From Our Partners