NYSEARCA:SBIO ALPS Medical Breakthroughs ETF (SBIO) Price, Holdings, & News $29.90 +0.22 (+0.74%) As of 03/27/2025 04:10 PM Eastern Add Compare Share Share Stock Analysis Stock AnalysisChartHoldingsOwnershipRatingsBuy This Stock About ALPS Medical Breakthroughs ETF (NYSEARCA:SBIO) 30 days 90 days 365 days Advanced Chart View Price History Chart DataSkip Price History Chart Get SBIO alerts:Sign Up Key Stats Today's Range$29.70▼$30.0650-Day Range$29.68▼$33.8352-Week Range$29.30▼$42.73Volume8,471 shsAverage Volume10,629 shsMarket Capitalization$89.70 millionAssets Under Management$86.82 millionDividend Yield3.91%Net Expense Ratio0.50%Aggregate RatingModerate Buy ETF OverviewThe ALPS Medical Breakthroughs ETF (SBIO) is an exchange-traded fund that is based on the S-Network Medical Breakthroughs index. The fund tracks, a market-cap weighted index comprising US-listed biotech companies with one or more drugs currently in either Phase II or Phase III FDA clinical trials. SBIO was launched on Dec 31, 2014 and is managed by ALPS.Read More… Remove Ads ALPS Medical Breakthroughs ETF ExpensesTypeSBIOHealth Care ETFsEquity ETFsNYSEARCA ETFsAll ETFsManagement Fee0.50%0.57%0.56%0.51%0.53%Other Expenses0.00%0.30%0.49%0.57%0.52%Total Expense0.50%0.70%0.72%0.73%0.71%Fee Waiver0.00%-0.45%-0.50%-0.66%-0.55%Net Expense0.50%0.61%0.63%0.58%0.60% Receive SBIO Stock News and Ratings via Email Sign-up to receive the latest news and ratings for ALPS Medical Breakthroughs ETF and its competitors with MarketBeat's FREE daily newsletter. Email Address SBIO ETF News HeadlinesSBIO ETF: Betting On Medical BreakthroughsDecember 14, 2024 | seekingalpha.comAdvacam & Vector Space Biosciences sign Letter of Intent (LOI) to Develop AI Models & CubeSat Payloads for the Space IndustryOctober 10, 2024 | businesswire.comTrump’s Great Society Trump’s Final Reset Inside the shocking plot to re-engineer America’s financial system…and why you need to move your money now.March 28, 2025 | Porter & Company (Ad)Why Biotech ETFs Are Beating the MarketSeptember 7, 2024 | msn.comALPS Medical Breakthroughs ETF (^SBIO-IV)July 19, 2024 | finance.yahoo.comHow does spaceflight lead to medical breakthroughs? Veteran astronaut explainsMay 22, 2024 | msn.comSee More Headlines SBIO ETF - Frequently Asked Questions How have SBIO shares performed this year? ALPS Medical Breakthroughs ETF's stock was trading at $33.03 at the start of the year. Since then, SBIO stock has decreased by 9.5% and is now trading at $29.90. View the best growth stocks for 2025 here. Who are ALPS Medical Breakthroughs ETF's major shareholders? ALPS Medical Breakthroughs ETF's top institutional shareholders include Bank of America Corp DE (4.13%), Wells Fargo & Company MN (3.96%), GTS Securities LLC (1.31%) and NTV Asset Management LLC (0.93%). How do I buy shares of ALPS Medical Breakthroughs ETF? Shares of SBIO stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services. What other stocks do shareholders of ALPS Medical Breakthroughs ETF own? Based on aggregate information from My MarketBeat watchlists, some other companies that ALPS Medical Breakthroughs ETF investors own include Waste Connections (WCN), American Water Works (AWK), iShares Micro-Cap ETF (IWC), The RMR Group (RMR), AUO (AUOTY), DiamondRock Hospitality (DRH) and Triple Flag Precious Metals (TFPM). Fund Details IssuerALPS Fund NameALPS Medical Breakthroughs ETF Tax ClassificationRegulated Investment Company Stock ExchangeNYSEARCACurrent SymbolNYSEARCA:SBIO Inception Date12/31/2014 Fund ManagerRyan Mischker, Andrew Hicks WebN/A PhoneN/AFund Focus Asset ClassEquity BenchmarkS-Network Medical Breakthroughs Index CategorySector FocusHealth Care Development LevelDeveloped Markets RegionNorth America Number of Holdings105 Fund Statistics Assets Under Management$86.82 million Average Daily Volume$11,543.20 Discount/Premium0.00% Administrator, Advisor and Custodian AdministratorALPS Fund Services, Inc. AdvisorALPS Advisors, Inc. CustodianState Street Bank and Trust Company DistributorALPS Portfolio Solutions Distributor, Inc. Transfer AgentState Street Bank and Trust Company TrusteeN/A Lead Market MakerGTS Options OptionableN/A Short Interest3,400 shs Miscellaneous Outstanding Shares3,000,000Beta0.91 Creation Unit50,000 Creation Fee$500.00 The 10 Best Stocks to Own: Spring 2025Discover the 10 best stocks to own in Spring 2025, carefully selected for their growth potential amid market volatility. This exclusive report highlights top companies poised to thrive in uncertain economic conditions—download now to gain an investing edge.Get This Free Report Top 10 SBIO HoldingsAxsome Therapeutics (NASDAQ:AXSM)Holding Weight: 5.01%Alkermes (NASDAQ:ALKS)Holding Weight: 4.71%Verona Pharma (NASDAQ:VRNA)Holding Weight: 4.48%PTC Therapeutics (NASDAQ:PTCT)Holding Weight: 3.44%Zai Lab (NASDAQ:ZLAB)Holding Weight: 3.37%Avidity Biosciences (NASDAQ:RNA)Holding Weight: 3.06%Merus (NASDAQ:MRUS)Holding Weight: 2.67%Rhythm Pharmaceuticals (NASDAQ:RYTM)Holding Weight: 2.64%Crinetics Pharmaceuticals (NASDAQ:CRNX)Holding Weight: 2.61%Akero Therapeutics (NASDAQ:AKRO)Holding Weight: 2.49%Full Holdings DetailsSBIO Sector ExposureSBIO Industry Exposure This page (NYSEARCA:SBIO) was last updated on 3/28/2025 by MarketBeat.com Staff From Our PartnersA $6.9 Trillion Cash Tsunami Is Coming – Move Your Money NOWExpert: "Prepare For the Mother of All Melt-Ups" In the wake of Wall Street volatility, stock-picking legen...Stansberry Research | SponsoredElon Warns: Exec Order 14024 Targets DollarExecutive Order 14024 is paving the way for irreversible damage to the dollar's value—threatening your wealth,...Priority Gold | SponsoredWarning: “DOGE Collapse” imminentElon Strikes Back You may already sense that the tide is turning against Elon Musk and DOGE. 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