SPDR S&P Biotech ETF (XBI) Holdings $85.60 -3.11 (-3.51%) Closing price 04:10 PM EasternExtended Trading$85.64 +0.04 (+0.05%) As of 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more. Add Compare Share Share Holdings Stock AnalysisChartDividendHeadlinesHoldingsOwnershipRatings Top 50 XBI HoldingsRankCompanyCurrent PriceWeightShares Held1GILDGilead Sciences$115.99+1.5%2.95%1,544,9362ABBVAbbVie$211.27+1.1%2.86%818,4633AMGNAmgen$310.78+0.9%2.82%521,9494BMRNBioMarin Pharmaceutical$71.02-0.2%2.64%2,163,4315INSMInsmed$76.29-6.5%2.56%1,923,4076INCYIncyte$70.26-4.4%2.51%1,968,7927VRTXVertex Pharmaceuticals$483.31+0.7%2.51%304,7908UTHRUnited Therapeutics$310.03-3.1%2.42%394,1429ALNYAlnylam Pharmaceuticals$243.53-1.3%2.36%561,50010HALOHalozyme Therapeutics$57.96-2.0%2.29%2,301,704 Get the Latest News and Ratings for XBI and Related StocksEnter your email address below to receive the latest news and analysts' ratings for SPDR S&P Biotech ETF and its competitors with MarketBeat's FREE daily newsletter. 11REGNRegeneron Pharmaceuticals$684.87-2.0%2.29%184,66812NTRANatera$143.11-8.0%2.28%853,97313BIIBBiogen$141.71+0.9%2.23%906,39914NBIXNeurocrine Biosciences$114.48-3.6%2.21%1,113,07015PCVXVaxcyte$72.10-1.3%2.13%1,567,55216SRPTSarepta Therapeutics$101.22-5.2%2.09%1,138,30917EXASExact Sciences$47.55+0.3%1.94%2,259,83818MRNAModerna$30.27-2.2%1.90%3,330,33619MDGLMadrigal Pharmaceuticals$313.47-8.1%1.87%352,31320TGTXTG Therapeutics$34.42+14.4%1.76%3,523,84221BBIOBridgeBio Pharma$33.01-5.4%1.57%2,661,22722BPMCBlueprint Medicines$89.75-7.1%1.48%945,23023ADMAADMA Biologics$15.83-3.4%1.44%5,456,87924EXELExelixis$38.55-0.4%1.43%2,252,96025CYTKCytokinetics$42.89-6.8%1.41%1,757,23226VKTXViking Therapeutics$25.70-11.0%1.40%2,883,56427IONSIonis Pharmaceuticals$32.60-1.8%1.38%2,524,02728ROIVRoivant Sciences$10.17-5.3%1.36%7,578,83329CRSPCRISPR Therapeutics$42.29-3.7%1.35%1,763,67630ALKSAlkermes$34.11-0.6%1.33%2,229,23731RVMDRevolution Medicines$38.34-5.9%1.30%1,837,59532SWTXSpringWorks Therapeutics$53.28-7.8%1.21%1,308,12933APLSApellis Pharmaceuticals$24.06-4.3%1.18%2,568,21934SMMTSummit Therapeutics$19.13-7.5%1.03%3,315,43135RNAAvidity Biosciences$29.22-4.6%0.94%1,882,59136BHVNBiohaven$31.93-14.1%0.90%1,438,92637KRYSKrystal Biotech$171.83-4.1%0.90%289,49738RXRXRecursion Pharmaceuticals$6.59-12.3%0.88%6,335,96339NUVLNuvalent$71.03-5.3%0.82%630,57740ACLXArcellx$62.63-3.4%0.81%755,856Your Wealth is Under Attack (Ad)Please don't wait—this is your moment to take action. Download your Wealth Protection Guide now, claim your free gift, and see how Trump's victory could spark major gains for gold.Click here now to see how to stop them in their tracks!41RAREUltragenyx Pharmaceutical$41.26-3.9%0.75%1,077,89142PTCTPTC Therapeutics$52.87-4.3%0.72%830,51843TWSTTwist Bioscience$37.11-4.4%0.69%992,85744TVTXTravere Therapeutics$19.80-7.5%0.66%1,877,85645AKROAkero Therapeutics$45.54-7.3%0.63%772,62246DVAXDynavax Technologies$13.53-1.9%0.61%2,642,27647PTGXProtagonist Therapeutics$38.50+2.4%0.61%1,016,13148BEAMBeam Therapeutics$25.10-4.7%0.60%1,178,11749CLDXCelldex Therapeutics$19.35-5.9%0.58%1,622,70350FOLDAmicus Therapeutics$9.13-3.8%0.55%3,535,283 Geographic ExposureUnited States94.3%Ireland1.5%Bermuda1.4%Switzerland1.3%Virgin Islands, British0.9%Canada0.1%Currency ExposureUSD100.0%Sector ExposureHealth Care73.6%Consumer Discretionary1.4%Energy0.1%Industry ExposureBiotechnology67.4%Health Care Equipment & Supplies3.7%Health Care Providers & Services2.3%Distributors1.2%Diversified Consumer Services0.2%Renewable Energy0.1%SubIndustry ExposureBiotechnology67.5%Life Sciences Tools & Services3.2%Health Care Services2.3%Pharmaceuticals0.6%Health Care Equipment0.5%Renewable Energy Equipment0.1%Health Care Supplies0.1%Coupon Exposure4-60.1%Maturity Exposure5-100.1% Related Companies and Tools Related Companies IBB Portfolio Companies IHI Portfolio Companies IXJ Portfolio Companies IYH Portfolio Companies FHLC Portfolio Companies FBT Portfolio Companies FXH Portfolio Companies RYH Portfolio Companies RSPH Portfolio Companies LABU Portfolio Companies This page (NYSEARCA:XBI) was last updated on 3/3/2025 by MarketBeat.com Staff From Our PartnersDOGE Social Security bombshell?Elon Musk just dropped another bombshell... 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