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SPDR S&P Biotech ETF (XBI) Holdings

SPDR S&P Biotech ETF logo
$80.89 +1.79 (+2.26%)
As of 04:10 PM Eastern

Top 50 XBI Holdings

RankCompanyCurrent PriceWeightShares Held
1
Natera, Inc. stock logo
NTRA
Natera
$152.45
+2.6%
2.82%903,619
2
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$491.33
-0.2%
2.71%263,546
3
Insmed Incorporated stock logo
INSM
Insmed
$69.78
-1.4%
2.70%1,763,560
4
Alnylam Pharmaceuticals, Inc. stock logo
ALNY
Alnylam Pharmaceuticals
$242.19
+0.1%
2.66%538,626
5
Neurocrine Biosciences, Inc. stock logo
NBIX
Neurocrine Biosciences
$104.86
+1.6%
2.55%1,197,184
6
United Therapeutics Co. stock logo
UTHR
United Therapeutics
$297.86
+1.5%
2.55%425,236
7
Gilead Sciences, Inc. stock logo
GILD
Gilead Sciences
$107.13
+0.7%
2.52%1,145,455
8
Exact Sciences Co. stock logo
EXAS
Exact Sciences
$44.82
+1.6%
2.47%2,817,156
9
Amgen Inc. stock logo
AMGN
Amgen
$281.05
+1.1%
2.44%417,859
10
Incyte Co. stock logo
INCY
Incyte
$58.34
+0.6%
2.36%1,927,814
11
Biogen Inc. stock logo
BIIB
Biogen
$119.83
+1.4%
2.33%931,439
12
Madrigal Pharmaceuticals, Inc. stock logo
MDGL
Madrigal Pharmaceuticals
$312.99
+1.4%
2.29%361,271
13
AbbVie Inc. stock logo
ABBV
AbbVie
$180.48
+1.9%
2.24%615,697
14
Regeneron Pharmaceuticals, Inc. stock logo
REGN
Regeneron Pharmaceuticals
$595.66
+1.3%
2.24%189,372
15
Blueprint Medicines Co. stock logo
BPMC
Blueprint Medicines
$85.92
+0.1%
2.14%1,199,854
16
Exelixis, Inc. stock logo
EXEL
Exelixis
$37.34
+1.5%
2.12%2,780,689
17
BioMarin Pharmaceutical Inc. stock logo
BMRN
BioMarin Pharmaceutical
$62.67
+1.2%
1.97%1,581,915
18
Moderna, Inc. stock logo
MRNA
Moderna
$26.86
+1.2%
1.94%3,729,624
19
TG Therapeutics, Inc. stock logo
TGTX
TG Therapeutics
$40.36
+2.2%
1.77%2,196,998
20
BridgeBio Pharma, Inc. stock logo
BBIO
BridgeBio Pharma
$35.74
+1.4%
1.74%2,441,793
21
Halozyme Therapeutics, Inc. stock logo
HALO
Halozyme Therapeutics
$59.21
+1.4%
1.66%1,342,272
22
Revolution Medicines, Inc. stock logo
RVMD
Revolution Medicines
$37.46
+0.1%
1.53%1,974,172
23
Cytokinetics, Incorporated stock logo
CYTK
Cytokinetics
$40.18
+5.7%
1.48%1,781,726
24
Summit Therapeutics Inc. stock logo
SMMT
Summit Therapeutics
$35.29
+6.2%
1.44%2,775,366
25
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
$38.83
+0.8%
1.40%1,764,112
26
Sarepta Therapeutics, Inc. stock logo
SRPT
Sarepta Therapeutics
$60.83
+2.2%
1.33%1,177,431
27
Roivant Sciences Ltd. stock logo
ROIV
Roivant Sciences
$10.90
+1.4%
1.28%5,988,835
28
Ionis Pharmaceuticals, Inc. stock logo
IONS
Ionis Pharmaceuticals
$29.44
+1.2%
1.27%2,129,145
29
ADMA Biologics, Inc. stock logo
ADMA
ADMA Biologics
$22.20
+2.1%
1.21%2,698,033
30
Viking Therapeutics, Inc. stock logo
VKTX
Viking Therapeutics
$25.62
-0.6%
1.12%2,220,181
31
SpringWorks Therapeutics, Inc. stock logo
SWTX
SpringWorks Therapeutics
$41.93
+1.8%
1.07%1,340,049
32
Krystal Biotech, Inc. stock logo
KRYS
Krystal Biotech
$167.94
+1.3%
1.04%291,955
33
Alkermes plc stock logo
ALKS
Alkermes
$27.84
+2.5%
1.03%1,817,554
34
Vaxcyte, Inc. stock logo
PCVX
Vaxcyte
$33.30
+0.4%
1.03%1,592,358
35
Avidity Biosciences, Inc. stock logo
RNA
Avidity Biosciences
$30.29
-1.3%
0.98%1,749,519
36
Nuvalent, Inc. stock logo
NUVL
Nuvalent
$72.14
-0.8%
0.93%618,443
37
Twist Bioscience Co. stock logo
TWST
Twist Bioscience
$39.38
+4.7%
0.93%1,199,353
38
Arcellx, Inc. stock logo
ACLX
Arcellx
$62.09
-2.4%
0.92%706,786
39
Rhythm Pharmaceuticals, Inc. stock logo
RYTM
Rhythm Pharmaceuticals
$62.65
+4.7%
0.91%697,442
40
Veracyte, Inc. stock logo
VCYT
Veracyte
$32.05
+1.8%
0.88%1,340,547
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41
Scholar Rock Holding Co. stock logo
SRRK
Scholar Rock
$33.33
+2.5%
0.87%1,349,021
42
Recursion Pharmaceuticals, Inc. stock logo
RXRX
Recursion Pharmaceuticals
$5.68
+1.7%
0.84%7,229,298
43
Apellis Pharmaceuticals, Inc. stock logo
APLS
Apellis Pharmaceuticals
$17.50
+0.0%
0.83%2,176,139
44
Soleno Therapeutics, Inc. stock logo
SLNO
Soleno Therapeutics
$73.03
+1.0%
0.82%560,011
45
Ultragenyx Pharmaceutical Inc. stock logo
RARE
Ultragenyx Pharmaceutical
$37.71
+1.1%
0.81%1,072,859
46
Crinetics Pharmaceuticals, Inc. stock logo
CRNX
Crinetics Pharmaceuticals
$32.04
-1.0%
0.79%1,233,713
47
ACADIA Pharmaceuticals Inc. stock logo
ACAD
ACADIA Pharmaceuticals
$14.70
+0.5%
0.75%2,419,655
48
Akero Therapeutics, Inc. stock logo
AKRO
Akero Therapeutics
$40.92
+3.3%
0.71%894,910
49
PTC Therapeutics, Inc. stock logo
PTCT
PTC Therapeutics
$49.19
-1.5%
0.69%689,437
50
Agios Pharmaceuticals, Inc. stock logo
AGIO
Agios Pharmaceuticals
$28.65
+1.0%
0.66%1,131,094

Geographic Exposure

  • United States
    94.8%
  • Switzerland
    1.4%
  • Bermuda
    1.3%
  • Ireland
    1.1%
  • Virgin Islands, British
    0.6%
  • Netherlands
    0.3%
  • Canada
    0.1%

Currency Exposure

  • USD
    100.0%

Sector Exposure

  • Health Care
    98.4%
  • Consumer Discretionary
    1.0%
  • Biotechnology
    0.5%

Industry Exposure

  • Biotechnology
    91.4%
  • Health Care Equipment & Supplies
    4.7%
  • Health Care Providers & Services
    2.7%
  • Distributors
    0.8%
  • Diversified Consumer Services
    0.2%

SubIndustry Exposure

  • Biotechnology
    91.4%
  • Life Sciences Tools & Services
    4.2%
  • Health Care Services
    2.7%
  • Pharmaceuticals
    0.7%
  • Health Care Equipment
    0.4%
  • Health Care Supplies
    0.1%

Coupon Exposure

  • 4-6
    0.1%

Maturity Exposure

  • 5-10
    0.1%

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This page (NYSEARCA:XBI) was last updated on 4/24/2025 by MarketBeat.com Staff
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