BerGenBio ASA is a clinical‐stage biopharmaceutical company developing novel therapies that target the AXL signaling pathway to address unmet medical needs in oncology and fibrotic diseases. The company’s proprietary platform is built around AXL, a receptor tyrosine kinase implicated in tumor progression, metastasis and treatment resistance, as well as in the development of fibrosis across multiple organ systems.
The company’s lead product candidate, bemcentinib (BGB324), is a first‐in‐class, selective AXL inhibitor being evaluated in multiple clinical trials for indications such as non‐small cell lung cancer, acute myeloid leukemia and mesothelioma. Bemcentinib has also been studied in combination with standard therapies and immune‐modulating agents. In addition to bemcentinib, BerGenBio’s pipeline includes BGB149, a monoclonal antibody designed to block AXL activity in fibrotic diseases, currently advancing through preclinical development.
Founded in 2013 as a spin‐out from the University of Bergen, BerGenBio is headquartered in Bergen, Norway, with research and clinical operations extending into the United Kingdom and the United States. The company collaborates with leading academic institutions, contract research organizations and regulatory agencies to design and execute its development programs. BerGenBio’s integrated research, regulatory and clinical teams work together to move candidates from discovery through late‐stage clinical validation.
Under the leadership of Chief Executive Officer Richard Godfrey, BerGenBio is focused on translating its AXL expertise into therapies that can improve outcomes for patients with serious and life-threatening diseases. The company continues to expand its portfolio by exploring additional indications for AXL inhibition and forging strategic partnerships to accelerate global development and commercialization efforts.
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