Sphera Funds Management Ltd. Top Holdings and 13F Report (2025) About Sphera Funds Management Ltd.Investment ActivitySphera Funds Management Ltd. has $553.15 million in total holdings as of December 31, 2024.Sphera Funds Management Ltd. owns shares of 103 different stocks, but just 50 companies or ETFs make up 80% of its holdings.Approximately 18.03% of the portfolio was purchased this quarter.About 23.84% of the portfolio was sold this quarter.This quarter, Sphera Funds Management Ltd. has purchased 109 new stocks and bought additional shares in 30 stocks.Sphera Funds Management Ltd. sold shares of 35 stocks and completely divested from 23 stocks this quarter.Largest Holdings Teva Pharmaceutical Industries $34,584,749BridgeBio Pharma $24,840,856Sanofi $18,545,158Syndax Pharmaceuticals $18,260,006AstraZeneca $14,745,931 Largest New Holdings this Quarter Alphabet $8,284,140 HoldingAnnexon $6,376,790 HoldingOrmat Technologies $5,349,880 HoldingSolarEdge Technologies $5,100,000 HoldingENGENE HOLDINGS INC $3,724,000 Holding Largest Purchases this Quarter Alphabet 43,500 shares (about $8.28M)Annexon 1,243,039 shares (about $6.38M)Ormat Technologies 79,000 shares (about $5.35M)Eledon Pharmaceuticals 1,254,298 shares (about $5.17M)SolarEdge Technologies 375,000 shares (about $5.10M) Largest Sales this Quarter Teva Pharmaceutical Industries 561,035 shares (about $12.37M)NICE 67,961 shares (about $11.54M)Amazon.com 43,000 shares (about $9.43M)PRAXIS PRECISION MEDICINES I 69,724 shares (about $5.37M)Meta Platforms 8,315 shares (about $4.87M) Sector Allocation Over TimeMap of 500 Largest Holdings ofSphera Funds Management Ltd. Selling Neutral Buying Latest 13F Holdings and Changes Since Previous Quarterly FilingIssuer NameHoldings ValueApproximate Purchase/SaleChange in SharesShares Held% of PortfolioSectorTEVATeva Pharmaceutical Industries$34,584,749$12,365,211 ▼-26.3%1,569,1816.3%MedicalBBIOBridgeBio Pharma$24,840,856$1,718,704 ▲7.4%905,2794.5%MedicalSNYSanofi$18,545,158$1,205,750 ▼-6.1%384,5153.4%MedicalSNDXSyndax Pharmaceuticals$18,260,006$4,579,342 ▲33.5%1,381,2413.3%MedicalAZNAstraZeneca$14,745,931$2,293,200 ▲18.4%225,0602.7%MedicalAMZNAmazon.com$13,735,350$9,433,770 ▼-40.7%62,6072.5%Retail/WholesalePRAXIS PRECISION MEDICINES I$13,435,908$5,365,959 ▼-28.5%174,5832.4%COM NEWNVMINova$13,421,355$3,187,833 ▲31.2%68,1462.4%Computer and TechnologyMETAMeta Platforms$12,296,296$4,868,516 ▼-28.4%21,0012.2%Computer and TechnologySRPTSarepta Therapeutics$12,027,804$3,395,401 ▼-22.0%98,9212.2%MedicalCLDXCelldex Therapeutics$11,980,583$1,389,850 ▲13.1%474,1032.2%MedicalELDNEledon Pharmaceuticals$10,512,670$5,167,708 ▲96.7%2,551,6191.9%MedicalLLYEli Lilly and Company$10,182,6800.0%13,1901.8%MedicalJNJJohnson & Johnson$10,098,9590.0%69,8311.8%MedicalRAREUltragenyx Pharmaceutical$9,624,606$1,406,274 ▲17.1%228,7761.7%MedicalCYTKCytokinetics$9,550,108$3,386,880 ▼-26.2%203,0211.7%MedicalMSFTMicrosoft$9,410,831$4,678,650 ▼-33.2%22,3271.7%Computer and TechnologyMRVLMarvell Technology$8,682,585$994,050 ▼-10.3%78,6111.6%Computer and TechnologyTSEMTower Semiconductor$8,558,335$2,229,971 ▼-20.7%166,1491.5%Computer and TechnologyNVONovo Nordisk A/S$8,436,842$1,720,400 ▲25.6%98,0801.5%MedicalWIXWix.com$8,421,731$1,072,750 ▲14.6%39,2531.5%Computer and TechnologyGOOGAlphabet$8,284,140$8,284,140 ▲New Holding43,5001.5%Computer and TechnologyPHVSPharvaris$7,441,468$979,760 ▼-11.6%388,1831.3%MedicalNICENICE$7,218,200$11,542,496 ▼-61.5%42,5001.3%Computer and TechnologyCHKPCheck Point Software Technologies$6,653,055$855,086 ▼-11.4%35,6351.2%Computer and TechnologyAPLSApellis Pharmaceuticals$6,581,469$307,038 ▼-4.5%206,2511.2%MedicalIMTXImmatics$6,549,099$1,422,000 ▲27.7%921,1111.2%MedicalANNXAnnexon$6,376,790$6,376,790 ▲New Holding1,243,0391.2%MedicalABBVAbbVie$6,087,291$665,309 ▼-9.9%34,2561.1%MedicalMRKMerck & Co., Inc.$5,929,0080.0%59,6001.1%MedicalJASPER THERAPEUTICS INC$5,864,962$512,051 ▲9.6%274,3201.1%COM NEWBHVNBiohaven$5,845,051$865,437 ▲17.4%156,4941.1%MedicalRZLTRezolute$5,712,886$152,111 ▼-2.6%1,165,8951.0%MedicalFROGJFrog$5,599,105$2,058,700 ▲58.1%190,3811.0%Computer and TechnologyDYNE THERAPEUTICS INC$5,566,333$4,235,099 ▲318.1%236,2621.0%COMMRUSMerus$5,488,871$719,097 ▼-11.6%130,5321.0%MedicalNTLAIntellia Therapeutics$5,434,493$2,040,500 ▲60.1%466,0801.0%MedicalORAOrmat Technologies$5,349,880$5,349,880 ▲New Holding79,0001.0%EnergyKURAKura Oncology$5,313,8580.0%610,0871.0%MedicalACADACADIA Pharmaceuticals$5,294,691$660,600 ▲14.3%288,5391.0%MedicalSEDGSolarEdge Technologies$5,100,000$5,100,000 ▲New Holding375,0000.9%EnergyORMAT TECHNOLOGIES INC$5,018,2510.0%5,037,0000.9%DEBT 2.500% 7/1NVSNovartis$4,865,5000.0%50,0000.9%MedicalCYBIN INC$4,746,140$3,484,906 ▼-42.3%538,1110.9%COM NEWSKYE BIOSCIENCE INC$4,427,897$3,130 ▲0.1%1,564,6280.8%COM NEWGSKGSK$4,396,600$1,014,600 ▲30.0%130,0000.8%MedicalETNB89bio$4,352,080$156,283 ▲3.7%556,5320.8%MedicalVIRVir Biotechnology$4,270,625$3,585,590 ▲523.4%581,8290.8%MedicalDAWNDay One Biopharmaceuticals$4,244,285$160,149 ▼-3.6%334,9870.8%MedicalVKTXViking Therapeutics$4,155,585$1,198,991 ▼-22.4%103,2700.8%MedicalPLRXPliant Therapeutics$3,916,2580.0%297,3620.7%MedicalAVGOBroadcom$3,913,4590.0%16,8800.7%Computer and TechnologySRRKScholar Rock$3,898,141$3,313,807 ▼-45.9%90,1930.7%MedicalTVTXTravere Therapeutics$3,844,594$871,000 ▲29.3%220,7000.7%MedicalENGENE HOLDINGS INC$3,724,000$3,724,000 ▲New Holding560,0000.7%COMSVRASavara$3,719,406$1,990,668 ▲115.2%1,211,5330.7%MedicalARWRArrowhead Pharmaceuticals$3,713,940$3,713,940 ▲New Holding197,5500.7%MedicalJANXJanux Therapeutics$3,658,549$3,658,549 ▲New Holding68,3330.7%MedicalALPHA COGNITION INC$3,651,800$3,651,800 ▲New Holding620,0000.7%COM NEWSWTXSpringWorks Therapeutics$3,613,000$3,613,000 ▲New Holding100,0000.7%MedicalBIIBBiogen$3,477,095$262,564 ▼-7.0%22,7380.6%MedicalENPHEnphase Energy$3,447,599$963,306 ▼-21.8%50,1980.6%EnergyRCKTRocket Pharmaceuticals$3,416,425$502,800 ▲17.3%271,7920.6%MedicalINZYInozyme Pharma$3,299,4580.0%1,191,1400.6%MedicalCAMTCamtek$2,930,9010.0%36,2870.5%Computer and TechnologyCRVSCorvus Pharmaceuticals$2,677,627$2,677,627 ▲New Holding500,4910.5%MedicalCARGO THERAPEUTICS INC$2,590,899$156,197 ▼-5.7%179,6740.5%COMWDAYWorkday$2,580,300$645,075 ▲33.3%10,0000.5%Computer and TechnologyVIGLVigil Neuroscience$2,554,129$246,797 ▼-8.8%1,502,4290.5%MedicalNTRNutrien$2,501,257$678,589 ▲37.2%55,8940.5%Basic MaterialsCGEMCullinan Therapeutics$2,496,900$232,991 ▲10.3%205,0000.5%MedicalPFEPfizer$2,387,7000.0%90,0000.4%MedicalVTGNVistagen Therapeutics$2,385,2230.0%808,5500.4%MedicalMLYSMineralys Therapeutics$2,347,172$1,006,958 ▼-30.0%190,6720.4%MedicalIONSIonis Pharmaceuticals$2,231,1820.0%63,8210.4%MedicalVTYXVentyx Biosciences$2,217,9200.0%1,012,7490.4%MedicalORICORIC Pharmaceuticals$2,204,829$1,168,673 ▲112.8%273,2130.4%MedicalCMMBChemomab Therapeutics$2,198,3810.0%1,214,5750.4%MedicalXENEXenon Pharmaceuticals$2,042,202$2,042,202 ▲New Holding52,0970.4%MedicalPMNProMIS Neurosciences$1,828,5880.0%1,929,2970.3%MedicalUBERUber Technologies$1,809,600$1,809,600 ▲New Holding30,0000.3%Computer and TechnologyLRMRLarimar Therapeutics$1,763,187$159,158 ▲9.9%455,6040.3%MedicalZURAZura Bio$1,726,795$120,000 ▼-6.5%690,7180.3%MedicalSHLTSHL Telemedicine$1,676,0080.0%632,4560.3%MedicalPERSPECTIVE THERAPEUTICS INC$1,468,188$411,663 ▼-21.9%460,2470.3%COM NEWATXSAstria Therapeutics$1,249,812$28,769 ▲2.4%139,8000.2%MedicalBMYBristol-Myers Squibb$1,131,200$1,131,200 ▲New Holding20,0000.2%MedicalMRSNMersana Therapeutics$987,089$987,089 ▲New Holding690,2720.2%MedicalALUMIS INC$982,5000.0%125,0000.2%COMHOWLWerewolf Therapeutics$927,6790.0%626,8100.2%MedicalAPREAprea Therapeutics$888,3000.0%270,0000.2%MedicalPERIPerion Network$869,124$1,118,015 ▼-56.3%102,6120.2%Computer and TechnologyONKURE THERAPEUTICS INC$751,244$751,244 ▲New Holding87,3540.1%COM CL AKEZAR LIFE SCIENCES INC$728,939$728,939 ▲New Holding108,4730.1%COM NEWFATEFate Therapeutics$655,342$655,342 ▲New Holding397,1770.1%MedicalALECAlector$613,568$558,233 ▼-47.6%324,6390.1%MedicalELEVElevation Oncology$573,043$34,431 ▼-5.7%1,018,5620.1%MedicalELYMEliem Therapeutics$453,483$125,937 ▲38.4%251,9350.1%MedicalKYVERNA THERAPEUTICS INC$444,155$485,800 ▼-52.2%118,7580.1%COMCGENCompugen$270,954$76,500 ▼-22.0%177,0940.0%MedicalShowing largest 100 holdings. View all holdings. More Institutional Buying and Selling Information SEC Filings and Trading Data SEC Filings 13F Filings Top 13F Buys Top 13F Sells Get 30 Days of MarketBeat All Access for Free Sign up for MarketBeat All Access to gain access to MarketBeat's full suite of research tools. Start Your 30-Day Trial MarketBeat All Access Features Best-in-Class Portfolio Monitoring Get personalized stock ideas. Compare portfolio to indices. Check stock news, ratings, SEC filings, and more. Stock Ideas and Recommendations See daily stock ideas from top analysts. Receive short-term trading ideas from MarketBeat. Identify trending stocks on social media. Advanced Stock Screeners and Research Tools Use our seven stock screeners to find suitable stocks. Stay informed with MarketBeat's real-time news. Export data to Excel for personal analysis. Sign in to your free account to enjoy these benefits In-depth profiles and analysis for 20,000 public companies. Real-time analyst ratings, insider transactions, earnings data, and more. Our daily ratings and market update email newsletter. Sign in to your free account to enjoy all that MarketBeat has to offer. Sign In Create Account Your Email Address: Email Address Required Your Password: Password Required Log In or Sign in with Facebook Sign in with Google Forgot your password? Your Email Address: Please enter your email address. Please enter a valid email address Choose a Password: Please enter your password. Your password must be at least 8 characters long and contain at least 1 number, 1 letter, and 1 special character. Create My Account (Free) or Sign in with Facebook Sign in with Google By creating a free account, you agree to our terms of service. This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
