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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
AMPH Amphastar Pharmaceuticals	$30.62 +1.2%	$24.60	$20.39 ▼ $53.96	$1.42B	0.8	631,383 shs	290,925 shs
CRSP CRISPR Therapeutics	$51.83 -2.3%	$55.74	$30.04 ▼ $71.13	$4.71B	1.81	2.53 million shs	1.59 million shs
MRUS Merus	$65.84 -0.4%	$61.26	$33.19 ▼ $69.20	$4.98B	1.19	589,242 shs	542,641 shs
NUVL Nuvalent	$76.58 +0.7%	$78.54	$55.53 ▼ $113.51	$5.52B	1.29	435,414 shs	418,360 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
AMPH Amphastar Pharmaceuticals	0.00%	+0.39%	+46.16%	+18.32%	-36.94%
CRSP CRISPR Therapeutics	0.00%	-4.58%	-7.87%	+43.81%	+9.16%
MRUS Merus	0.00%	-2.44%	-0.60%	+18.23%	+27.18%
NUVL Nuvalent	0.00%	+0.66%	-2.26%	+4.01%	-9.55%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
AMPH Amphastar Pharmaceuticals	3.298 of 5 stars	1.2	1.0	3.7	3.6	4.2	1.3
CRSP CRISPR Therapeutics	3.5962 of 5 stars	4.2	3.0	0.0	2.3	3.3	0.6
MRUS Merus	2.0935 of 5 stars	3.5	1.0	0.0	2.8	2.5	0.0
NUVL Nuvalent	3.3727 of 5 stars	4.5	1.0	0.0	3.7	3.3	0.0

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
AMPH Amphastar Pharmaceuticals	2.40	Hold	$31.60	3.20% Upside
CRSP CRISPR Therapeutics	2.47	Hold	$71.60	38.14% Upside
MRUS Merus	3.08	Buy	$88.75	34.80% Upside
NUVL Nuvalent	3.09	Buy	$120.80	57.74% Upside

Current Analyst Ratings Breakdown

Latest AMPH, NUVL, MRUS, and CRSP Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
8/26/2025	AMPH Amphastar Pharmaceuticals	Bank of America Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Neutral ➝ Neutral	$28.00 ➝ $32.00
8/26/2025	CRSP CRISPR Therapeutics	Zacks Research Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Strong Sell ➝ Hold
8/25/2025	MRUS Merus	Industrial Alliance Securities Subscribe to MarketBeat All Access for the recommendation accuracy rating	Set Price Target		$90.00
8/25/2025	MRUS Merus	Alliance Global Partners Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy	$90.00
8/19/2025	NUVL Nuvalent	Piper Sandler Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Overweight	$112.00
8/12/2025	AMPH Amphastar Pharmaceuticals	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Hold ➝ Buy	$36.00
8/8/2025	AMPH Amphastar Pharmaceuticals	Piper Sandler Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Neutral ➝ Neutral	$30.00 ➝ $25.00
8/7/2025	CRSP CRISPR Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$65.00 ➝ $80.00
8/6/2025	CRSP CRISPR Therapeutics	Barclays Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Equal Weight ➝ Equal Weight	$42.00 ➝ $56.00
8/6/2025	MRUS Merus	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Strong-Buy
8/6/2025	MRUS Merus	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Buy ➝ Buy	$97.00 ➝ $96.00

(Data available from 8/31/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
AMPH Amphastar Pharmaceuticals	$731.97M	1.94	$5.00 per share	6.12	$15.23 per share	2.01
CRSP CRISPR Therapeutics	$37.31M	126.35	N/A	N/A	$22.64 per share	2.29
MRUS Merus	$36.13M	137.82	N/A	N/A	$9.46 per share	6.96
NUVL Nuvalent	N/A	N/A	N/A	N/A	$14.99 per share	N/A

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
AMPH Amphastar Pharmaceuticals	$159.52M	$2.67	11.47	9.31	N/A	18.64%	20.76%	9.68%	11/5/2025 (Estimated)
CRSP CRISPR Therapeutics	-$366.25M	-$5.43	N/A	N/A	N/A	-1,229.43%	-20.05%	-17.09%	11/4/2025 (Estimated)
MRUS Merus	-$215.33M	-$5.50	N/A	N/A	N/A	-685.64%	-50.28%	-42.00%	10/30/2025 (Estimated)
NUVL Nuvalent	-$260.76M	-$4.90	N/A	N/A	N/A	N/A	-32.58%	-30.14%	11/11/2025 (Estimated)

Latest AMPH, NUVL, MRUS, and CRSP Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/7/2025	Q2 2025	NUVL Nuvalent	-$1.27	-$1.31	-$0.04	-$1.39	N/A	N/A
8/5/2025	Q1 2025	MRUS Merus	-$1.17	-$2.23	-$1.06	-$2.23	$9.77 million	$8.83 million
8/4/2025	Q2 2025	CRSP CRISPR Therapeutics	-$1.47	-$1.29	+$0.18	-$2.40	$6.44 million	$0.89 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
AMPH Amphastar Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
CRSP CRISPR Therapeutics	N/A	N/A	N/A	N/A	N/A
MRUS Merus	N/A	N/A	N/A	N/A	N/A
NUVL Nuvalent	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
AMPH Amphastar Pharmaceuticals	0.80	3.29	2.21
CRSP CRISPR Therapeutics	N/A	16.61	16.61
MRUS Merus	N/A	8.39	8.39
NUVL Nuvalent	N/A	13.57	13.57

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
AMPH Amphastar Pharmaceuticals	65.09%
CRSP CRISPR Therapeutics	69.20%
MRUS Merus	96.14%
NUVL Nuvalent	97.26%

Insider Ownership

Company	Insider Ownership
AMPH Amphastar Pharmaceuticals	27.10%
CRSP CRISPR Therapeutics	4.10%
MRUS Merus	3.70%
NUVL Nuvalent	10.20%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
AMPH Amphastar Pharmaceuticals	2,028	46.49 million	33.90 million	Optionable
CRSP CRISPR Therapeutics	460	90.95 million	87.22 million	Optionable
MRUS Merus	37	75.63 million	72.84 million	Optionable
NUVL Nuvalent	40	72.11 million	64.75 million	Optionable

AMPH, NUVL, MRUS, and CRSP Headlines

Recent News About These Companies

Driehaus Capital Management LLC Has $37.67 Million Stock Position in Nuvalent, Inc. $NUVL

August 31 at 7:14 AM | marketbeat.com

Nuvalent, Inc. (NASDAQ:NUVL) Receives Consensus Recommendation of "Buy" from Analysts

August 31 at 2:11 AM | marketbeat.com

Nuvalent, Inc. $NUVL Shares Bought by Tema Etfs LLC

August 30 at 8:19 AM | marketbeat.com

Tri Locum Partners LP Makes New $6.80 Million Investment in Nuvalent, Inc. $NUVL

August 30 at 8:04 AM | marketbeat.com

Nuvalent, Inc. $NUVL Shares Sold by Jump Financial LLC

August 30 at 5:00 AM | marketbeat.com

Nuvalent, Inc. $NUVL Holdings Raised by Affinity Asset Advisors LLC

August 28 at 9:02 AM | marketbeat.com

Nuvalent to Participate in the Cantor Global Healthcare Conference 2025

August 28 at 6:30 AM | prnewswire.com

Price T Rowe Associates Inc. MD Raises Stock Position in Nuvalent, Inc. $NUVL

August 28 at 4:52 AM | marketbeat.com

Nuveen LLC Buys Shares of 83,976 Nuvalent, Inc. $NUVL

August 28 at 3:36 AM | marketbeat.com

T. Rowe Price Investment Management Inc. Makes New $31.97 Million Investment in Nuvalent, Inc. $NUVL

August 26, 2025 | marketbeat.com

Nuvalent, Inc. $NUVL Shares Purchased by American Century Companies Inc.

August 26, 2025 | marketbeat.com

Nuvalent, Inc. $NUVL Shares Purchased by Wellington Management Group LLP

August 24, 2025 | marketbeat.com

Nuvalent, Inc. $NUVL Shares Sold by Deutsche Bank AG

August 24, 2025 | marketbeat.com

Nuvalent, Inc. $NUVL Shares Sold by Charles Schwab Investment Management Inc.

August 24, 2025 | marketbeat.com

Candriam S.C.A. Sells 13,966 Shares of Nuvalent, Inc. $NUVL

August 23, 2025 | marketbeat.com

Aberdeen Group plc Acquires 19,987 Shares of Nuvalent, Inc. $NUVL

August 23, 2025 | marketbeat.com

Nuvalent, Inc. $NUVL Shares Purchased by Russell Investments Group Ltd.

August 22, 2025 | marketbeat.com

Nuvalent (NASDAQ:NUVL) CEO Sells $2,036,340.00 in Stock

August 21, 2025 | marketbeat.com

Nuvalent (NASDAQ:NUVL) Now Covered by Piper Sandler

August 21, 2025 | marketbeat.com

Insider Selling: Nuvalent (NASDAQ:NUVL) CEO Sells 27,000 Shares of Stock

August 20, 2025 | insidertrades.com

Piper Sandler Initiates Coverage of Nuvalent (NUVL) with Overweight Recommendation

August 19, 2025 | msn.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

AMPH, NUVL, MRUS, and CRSP Company Descriptions

Amphastar Pharmaceuticals NASDAQ:AMPH

$30.62 +0.36 (+1.19%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$30.64 +0.02 (+0.08%)

As of 08/29/2025 05:31 PM Eastern

Amphastar Pharmaceuticals, Inc., a bio-pharmaceutical company, develops, manufactures, markets, and sells generic and proprietary injectable, inhalation, and intranasal products in the United States, China, and France. It offers BAQSIMI, a nasal spray for the treatment of severe hypoglycemia; Primatene Mist, an over-the-counter epinephrine inhalation product for the temporary relief of mild symptoms of intermittent asthma; Enoxaparin, to prevent and treat deep vein thrombosis; REXTOVY and Naloxone for opioid overdose; Glucagon for injection emergency kit; and Cortrosyn, for use as a diagnostic agent in the screening of patients with adrenocortical insufficiency. The company provides Amphadase, an injection to absorb and disperse other injected drugs; Epinephrine injection for allergic reactions; Lidocaine jelly, an anesthetic product for urological procedures; Lidocaine topical solution for various procedures; Phytonadione injection, a vitamin K1 injection for newborn babies; emergency syringe products; morphine injection for use with patient-controlled analgesia pumps; and Lorazepam injection for surgery and medical procedures. In addition, it offers Neostigmine methylsulfate injection to treat myasthenia gravis and to reverse the effects of muscle relaxants; Isoproterenol hydrochloride injection for mild or transient episodes of heart block; Ganirelix Acetate injection for the inhibition of premature luteinizing hormone surges; Vasopressin to increase blood pressure; and Regadenoson, a stress agent for radionuclide myocardial perfusion imaging. Further, the company distributes recombinant human insulin APIs and porcine insulin API. Additionally, it develops generic product candidates, such as injectable, inhalation, and analytical technologies; biosimial product candidates; and intranasal epinephrine for the treatment of allergic reactions. The company was founded in 1996 and is headquartered in Rancho Cucamonga, California.

CRISPR Therapeutics NASDAQ:CRSP

$51.83 -1.22 (-2.30%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$51.80 -0.03 (-0.06%)

As of 08/29/2025 07:59 PM Eastern

CRISPR Therapeutics is a gene-editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom. For more information, please visit www.crisprtx.com.

Merus NASDAQ:MRUS

$65.84 -0.26 (-0.39%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$65.84 +0.00 (+0.01%)

As of 08/29/2025 07:30 PM Eastern

Merus N.V., a clinical-stage immuno-oncology company, engages in the development of antibody therapeutics in the Netherlands. Its bispecific antibody candidate pipeline includes Zenocutuzumab (MCLA-128), which is in a phase 2 clinical trials for the treatment of patients with metastatic breast cancer and castration-resistant prostate cancer, as well as in Phase 1/2 clinical trials for the treatment of solid tumors that harbor Neuregulin 1. The company is also developing MCLA-158, which is in a phase I clinical trial for the treatment of solid tumors; MCLA-145, which is in phase 1 clinical trials for the treatment of solid tumors; MCLA-129, which is in phase 1/2 clinical trials for the treatment of patients with advanced non-small cell lung cancer and other solid tumors; and ONO-4685 that is Phase 1 clinical trial to treat relapsed/refractory T cell lymphoma. In addition, it has collaboration agreement with Betta Pharmaceuticals Co. Ltd for the research and development of stage bispecific antibody candidates include MCLA-129; collaboration with Incyte Corporation for the development of MCLA-145; and collaboration with Gilead Sciences, Inc. to discover novel antibody-based trispecific T-cell engagers. The company was incorporated in 2003 and is headquartered in Utrecht, the Netherlands.

Nuvalent NASDAQ:NUVL

$76.58 +0.56 (+0.74%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$76.60 +0.02 (+0.02%)

As of 08/29/2025 04:38 PM Eastern

Nuvalent, Inc., a clinical stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the phase 2 portion of the ALKOVE-1 Phase 1/2 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR, which is expected to initiate phase 1 trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.

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Comparative Price Performance Over Time