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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Biogen Inc. stock logo
BIIB
Biogen
$138.37
-1.4%
$141.88
$128.51
$238.00
$20.25B0.011.30 million shs1.09 million shs
bluebird bio, Inc. stock logo
BLUE
bluebird bio
$4.08
+7.7%
$5.53
$3.56
$28.60
$39.67M0.76363,888 shs2.08 million shs
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
$36.99
-2.8%
$43.10
$36.52
$68.39
$3.26B1.771.55 million shs1.60 million shs
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
$69.36
-1.1%
$82.33
$69.18
$148.15
$311.23B0.425.56 million shs5.85 million shs
Novartis AG stock logo
NVS
Novartis
$112.69
+1.2%
$107.92
$92.35
$120.92
$230.34B0.531.49 million shs2.54 million shs
Pfizer Inc. stock logo
PFE
Pfizer
$25.20
+0.8%
$26.06
$24.48
$31.54
$142.93B0.6139.04 million shs32.32 million shs
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
$0.82
-4.4%
$1.04
$0.30
$3.18
$184.26M1.497.76 million shs1.96 million shs
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$492.69
-2.0%
$476.45
$377.85
$519.88
$126.52B0.411.28 million shs1.28 million shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Biogen Inc. stock logo
BIIB
Biogen
-1.47%-0.74%-2.18%-7.26%-35.13%
bluebird bio, Inc. stock logo
BLUE
bluebird bio
+1.07%-4.29%-5.72%-56.83%-86.12%
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
-2.91%-7.60%-14.54%-4.95%-45.78%
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
-2.18%-10.87%-22.83%-19.68%-45.19%
Novartis AG stock logo
NVS
Novartis
+1.25%-1.67%+1.58%+13.28%+16.25%
Pfizer Inc. stock logo
PFE
Pfizer
-0.56%-4.26%-6.37%-5.89%-9.79%
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
+1.46%+2.17%-10.33%-66.51%+37.23%
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
+0.45%-1.50%+4.62%+22.95%+20.42%
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CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Biogen Inc. stock logo
BIIB
Biogen
4.9108 of 5 stars
4.25.00.03.73.42.51.9
bluebird bio, Inc. stock logo
BLUE
bluebird bio
2.8662 of 5 stars
3.13.00.00.02.52.51.3
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
3.3013 of 5 stars
4.22.00.00.02.13.30.6
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
4.8113 of 5 stars
4.45.01.70.02.40.04.4
Novartis AG stock logo
NVS
Novartis
3.0286 of 5 stars
1.95.02.50.03.40.01.9
Pfizer Inc. stock logo
PFE
Pfizer
4.9874 of 5 stars
3.33.04.24.23.33.33.1
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
2.7273 of 5 stars
4.31.00.00.03.30.80.6
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
3.8868 of 5 stars
2.33.00.03.33.02.51.3
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Biogen Inc. stock logo
BIIB
Biogen
2.43
Hold$213.3354.18% Upside
bluebird bio, Inc. stock logo
BLUE
bluebird bio
2.25
Hold$51.001,150.00% Upside
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
2.48
Hold$73.1197.64% Upside
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
2.80
Moderate Buy$145.25109.43% Upside
Novartis AG stock logo
NVS
Novartis
1.80
Reduce$123.389.48% Upside
Pfizer Inc. stock logo
PFE
Pfizer
2.63
Moderate Buy$31.9226.67% Upside
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
2.67
Moderate Buy$5.17530.08% Upside
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
2.65
Moderate Buy$506.702.84% Upside

Current Analyst Ratings Breakdown

Latest BLUE, SGMO, VRTX, CRSP, NVO, NVS, BIIB, and PFE Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
3/18/2025
Pfizer Inc. stock logo
PFE
Pfizer
Guggenheim
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Reiterated RatingBuy ➝ Buy
3/18/2025
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
Royal Bank of Canada
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Reiterated RatingSector Perform ➝ Sector Perform$2.00 ➝ $2.00
3/13/2025
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
Kepler Capital Markets
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UpgradeHold ➝ Buy
3/12/2025
Pfizer Inc. stock logo
PFE
Pfizer
Guggenheim
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Reiterated RatingBuy ➝ Buy
3/10/2025
Pfizer Inc. stock logo
PFE
Pfizer
Hsbc Global Res
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UpgradeStrong-Buy
3/3/2025
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
Stifel Nicolaus
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DowngradeBuy ➝ Hold
2/24/2025
bluebird bio, Inc. stock logo
BLUE
bluebird bio
Wells Fargo & Company
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetEqual Weight ➝ Equal Weight$40.00 ➝ $5.00
2/24/2025
bluebird bio, Inc. stock logo
BLUE
bluebird bio
JPMorgan Chase & Co.
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UpgradeUnderweight ➝ Neutral
2/21/2025
bluebird bio, Inc. stock logo
BLUE
bluebird bio
Baird R W
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DowngradeStrong-Buy ➝ Hold
2/20/2025
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
Royal Bank of Canada
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Boost Price TargetSector Perform ➝ Sector Perform$407.00 ➝ $408.00
2/19/2025
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
Cantor Fitzgerald
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Reiterated RatingNeutral ➝ Neutral
(Data available from 3/28/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Biogen Inc. stock logo
BIIB
Biogen
$9.68B2.09$22.72 per share6.09$114.71 per share1.21
bluebird bio, Inc. stock logo
BLUE
bluebird bio
$53.12M0.75N/AN/A$35.59 per share0.11
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
$35M90.65N/AN/A$22.52 per share1.64
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
$290.40B1.07$3.22 per share21.57$4.64 per share14.95
Novartis AG stock logo
NVS
Novartis
$51.72B4.45$11.24 per share10.03$21.59 per share5.22
Pfizer Inc. stock logo
PFE
Pfizer
$63.63B2.25$3.95 per share6.38$15.81 per share1.59
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
$57.80M3.19$0.03 per share30.42$0.47 per share1.74
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$11.02B11.48N/AN/A$63.90 per share7.71
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Biogen Inc. stock logo
BIIB
Biogen
$1.63B$11.1912.378.381.5116.87%14.98%8.76%4/23/2025 (Estimated)
bluebird bio, Inc. stock logo
BLUE
bluebird bio
-$211.91M-$37.40N/AN/AN/A-565.74%-322.46%-53.17%5/7/2025 (Estimated)
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
-$366.25M-$4.37N/AN/AN/A-981.54%-18.46%-15.79%5/6/2025 (Estimated)
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
$14.64B$3.2921.0814.880.9034.81%84.68%26.29%5/1/2025 (Estimated)
Novartis AG stock logo
NVS
Novartis
$11.94B$5.8819.1712.791.7023.56%37.24%15.85%4/29/2025 (Estimated)
Pfizer Inc. stock logo
PFE
Pfizer
$8.03B$1.4117.878.320.6412.62%19.47%8.09%4/29/2025 (Estimated)
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
-$257.83M-$0.52N/AN/AN/A-257.87%-264.16%-107.24%5/8/2025 (Estimated)
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
-$535.60M-$2.20N/A28.142.11-4.86%-2.02%-1.49%5/5/2025 (Estimated)

Latest BLUE, SGMO, VRTX, CRSP, NVO, NVS, BIIB, and PFE Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
4/23/2025N/A
Biogen Inc. stock logo
BIIB
Biogen
$3.59N/AN/AN/A$2.25 billionN/A
4/22/2025N/A
Novartis AG stock logo
NVS
Novartis
$2.07N/AN/AN/AN/AN/A
3/17/2025Q4 2024
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
-$0.09-$0.11-$0.02-$0.11$11.70 million$7.55 million
2/12/2025Q4 2024
Biogen Inc. stock logo
BIIB
Biogen
$3.43$3.44+$0.01$1.83$2.42 billionN/A
2/11/2025Q4 2024
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
-$1.15-$0.44+$0.71-$0.44N/AN/A
2/10/2025Q4 2024
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
$3.99$3.54-$0.45$3.50$2.78 billionN/A
2/5/2025Q4 2024
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
$0.88$0.91+$0.03$0.91N/AN/A
2/4/2025Q4 2024
Pfizer Inc. stock logo
PFE
Pfizer
$0.48$0.63+$0.15$0.07$17.26 billion$17.76 billion
1/31/2025Q4 2024
Novartis AG stock logo
NVS
Novartis
$1.80$1.98+$0.18$1.41$12.86 billionN/A
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Biogen Inc. stock logo
BIIB
Biogen
N/AN/AN/AN/AN/A
bluebird bio, Inc. stock logo
BLUE
bluebird bio
N/AN/AN/AN/AN/A
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
N/AN/AN/AN/AN/A
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
$1.572.26%+25.26%47.72%N/A
Novartis AG stock logo
NVS
Novartis
$2.512.23%+5.34%42.69%N/A
Pfizer Inc. stock logo
PFE
Pfizer
$1.726.83%+2.50%121.99%16 Years
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
N/AN/AN/AN/AN/A
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
N/AN/AN/AN/AN/A

Latest BLUE, SGMO, VRTX, CRSP, NVO, NVS, BIIB, and PFE Dividends

AnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date
2/5/2025
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
semi-annual$0.78741.2%3/31/20253/31/20254/8/2025
2/20/2025
Novartis AG stock logo
NVS
Novartis
$3.86953/12/20253/12/20253/12/2025
(Data available from 1/1/2013 forward)
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Biogen Inc. stock logo
BIIB
Biogen
0.27
1.35
0.90
bluebird bio, Inc. stock logo
BLUE
bluebird bio
0.37
0.51
0.33
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
N/A
22.07
22.07
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
0.62
0.74
0.55
Novartis AG stock logo
NVS
Novartis
0.48
1.04
0.84
Pfizer Inc. stock logo
PFE
Pfizer
0.63
1.00
0.73
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
N/A
1.35
1.35
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
0.01
2.69
2.35
CompanyEmployeesShares OutstandingFree FloatOptionable
Biogen Inc. stock logo
BIIB
Biogen
8,720146.38 million146.14 millionOptionable
bluebird bio, Inc. stock logo
BLUE
bluebird bio
5209.72 million9.59 millionOptionable
CRISPR Therapeutics AG stock logo
CRSP
CRISPR Therapeutics
47385.77 million82.26 millionOptionable
Novo Nordisk A/S stock logo
NVO
Novo Nordisk A/S
54,4004.49 billion4.48 billionOptionable
Novartis AG stock logo
NVS
Novartis
101,7002.04 billion2.04 billionOptionable
Pfizer Inc. stock logo
PFE
Pfizer
83,0005.67 billion5.66 billionOptionable
Sangamo Therapeutics, Inc. stock logo
SGMO
Sangamo Therapeutics
480224.71 million202.81 millionOptionable
Vertex Pharmaceuticals Incorporated stock logo
VRTX
Vertex Pharmaceuticals
6,100256.79 million256.28 millionOptionable

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Biogen stock logo

Biogen NASDAQ:BIIB

$138.37 -1.96 (-1.40%)
Closing price 04:00 PM Eastern
Extended Trading
$137.85 -0.52 (-0.37%)
As of 07:49 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Biogen Inc. discovers, develops, manufactures, and delivers therapies for treating neurological and neurodegenerative diseases in the United States, Europe, Germany, Asia, and internationally. The company provides TECFIDERA, VUMERITY, AVONEX, PLEGRIDY, TYSABRI, and FAMPYRA for multiple sclerosis (MS); SPINRAZA for spinal muscular atrophy; ADUHELM to treat Alzheimer's disease; FUMADERM to treat plaque psoriasis; BENEPALI, an etanercept biosimilar referencing ENBREL; IMRALDI, an adalimumab biosimilar referencing HUMIRA; FLIXABI, an infliximab biosimilar referencing REMICADE; and BYOOVIZ, a ranibizumab biosimilar referencing LUCENTIS. It offers RITUXAN for treating non-Hodgkin's lymphoma, chronic lymphocytic leukemia (CLL), rheumatoid arthritis, two forms of ANCA-associated vasculitis, and pemphigus vulgaris; RITUXAN HYCELA for non-Hodgkin's lymphoma and CLL; GAZYVA to treat CLL and follicular lymphoma; OCREVUS for relapsing MS and primary progressive MS; LUNSUMIO to treat relapsed or refractory follicular lymphoma; glofitamab for non-Hodgkin's lymphoma; and other anti-CD20 therapies. In addition, the company is developing various products for the treatment of MS, Alzheimer's disease and dementia, neuromuscular disorders, Parkinson's disease and movement disorders, neuropsychiatry, genetic neurodevelopmental disorders, and biosimilars, which are under various stages of development. It has collaboration and license agreements with Acorda Therapeutics, Inc.; Alkermes Pharma Ireland Limited; Denali Therapeutics Inc.; Eisai Co., Ltd.; Genentech, Inc.; Neurimmune SubOne AG; Ionis Pharmaceuticals, Inc.; Samsung Bioepis Co., Ltd.; Sangamo Therapeutics, Inc.; and Sage Therapeutics, Inc., as well as collaboration with Fujirebio to potentially identify and develop blood-based biomarkers for tau pathology in the brain. The company was founded in 1978 and is headquartered in Cambridge, Massachusetts.

bluebird bio stock logo

bluebird bio NASDAQ:BLUE

$4.08 +0.29 (+7.65%)
Closing price 04:00 PM Eastern
Extended Trading
$4.45 +0.37 (+9.07%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

bluebird bio, Inc., a biotechnology company, researches, develops, and commercializes gene therapies for severe genetic diseases. Its product candidates for severe genetic diseases include ZYNTEGLO (betibeglogene autotemcel) for the treatment of transfusion-dependent ß-thalassemia; lovotibeglogene autotemcel for the treatment of sickle cell disease (SCD); and SKYSONA (elivaldogene autotemcel) to treat cerebral adrenoleukodystrophy. The company's clinical development programs include HGB-205, HGB-206, and HGB-210 to evaluate the safety and efficacy of lovo-cel in the treatment of patients with SCD; and HGB-204, HGB-205, HGB-207, and HGB-212 to evaluate the safety and efficacy of beti-cel in the treatment of patients with ß-thalassemia. It has license agreement with Orchard Therapeutics Limited. The company was formerly known as Genetix Pharmaceuticals, Inc., and changed its name to bluebird bio, Inc. in September 2010. bluebird bio, Inc. was incorporated in 1992 and is headquartered in Somerville, Massachusetts.

CRISPR Therapeutics stock logo

CRISPR Therapeutics NASDAQ:CRSP

$36.99 -1.05 (-2.76%)
Closing price 04:00 PM Eastern
Extended Trading
$36.90 -0.09 (-0.24%)
As of 07:57 PM Eastern
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CRISPR Therapeutics is a gene-editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom. For more information, please visit www.crisprtx.com.

Novo Nordisk A/S stock logo

Novo Nordisk A/S NYSE:NVO

$69.36 -0.81 (-1.15%)
Closing price 03:59 PM Eastern
Extended Trading
$69.36 +0.01 (+0.01%)
As of 07:59 PM Eastern
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Novo Nordisk A/S, together with its subsidiaries, engages in the research and development, manufacture, and distribution of pharmaceutical products in Europe, the Middle East, Africa, Mainland China, Hong Kong, Taiwan, North America, and internationally. It operates in two segments, Diabetes and Obesity Care, and Rare Disease. The Diabetes and Obesity care segment provides products for diabetes, obesity, cardiovascular, and other emerging therapy areas. The Rare Disease segment offers products in the areas of rare blood disorders, rare endocrine disorders, and hormone replacement therapy. The company also provides insulin pens, growth hormone pens, and injection needles. In addition, it offers smart solutions for diabetes treatment, such as smart insulin pens and Dose Check, an insulin dose guidance application. The company has a collaboration agreement with Aspen Pharmaceuticals to produce insulin products; and with Korro Bio, Inc. for the discovery and development of new genetic medicines to treat cardiometabolic diseases. Novo Nordisk A/S was founded in 1923 and is headquartered in Bagsvaerd, Denmark.

Novartis stock logo

Novartis NYSE:NVS

$112.69 +1.29 (+1.16%)
Closing price 03:59 PM Eastern
Extended Trading
$113.99 +1.30 (+1.15%)
As of 07:52 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Novartis AG engages in the research, development, manufacture, and marketing of healthcare products in Switzerland and internationally. The company offers prescription medicines for patients and physicians. It focuses on therapeutic areas, such as cardiovascular, renal and metabolic, immunology, neuroscience, and oncology, as well as ophthalmology and hematology. Novartis AG has a license and collaboration agreement with Alnylam Pharmaceuticals to develop, manufacture, and commercialize inclisiran, a therapy to reduce LDL cholesterol; and Dawn Health for the development and commercialization of Ekiva, a digital solution designed for people living with Paroxysmal Nocturnal Hemoglobinuria. The company was incorporated in 1996 and is headquartered in Basel, Switzerland.

Pfizer stock logo

Pfizer NYSE:PFE

$25.20 +0.19 (+0.76%)
Closing price 03:59 PM Eastern
Extended Trading
$25.14 -0.07 (-0.26%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Pfizer Inc. discovers, develops, manufactures, markets, distributes, and sells biopharmaceutical products in the United States, Europe, and internationally. The company offers medicines and vaccines in various therapeutic areas, including cardiovascular metabolic, migraine, and women's health under the Eliquis, Nurtec ODT/Vydura, Zavzpret, and the Premarin family brands; infectious diseases with unmet medical needs under the Prevnar family, Abrysvo, Nimenrix, FSME/IMMUN-TicoVac, and Trumenba brands; and COVID-19 prevention and treatment, and potential future mRNA and antiviral products under the Comirnaty and Paxlovid brands. It also provides medicines and vaccines in various therapeutic areas, such as biosimilars for chronic immune and inflammatory diseases under the Xeljanz, Enbrel, Inflectra, Litfulo, Velsipity, and Cibinqo brands; amyloidosis, hemophilia, endocrine diseases, and sickle cell disease under the Vyndaqel family, Oxbryta, BeneFIX, Somavert, Ngenla, and Genotropin brands; sterile injectable and anti-infective medicines under the Sulperazon, Medrol, Zavicefta, Zithromax, and Panzyga brands; and biologics, small molecules, immunotherapies, and biosimilars under the Ibrance, Xtandi, Inlyta, Bosulif, Mektovi, Padcev, Adcetris, Talzenna, Tukysa, Elrexfio, Tivdak, Lorbrena, and Braftovi brands. In addition, the company involved in the contract manufacturing business. It serves wholesalers, retailers, hospitals, clinics, government agencies, pharmacies, individual provider offices, retail pharmacies, and integrated delivery systems. The company has collaboration agreements with Bristol-Myers Squibb Company; Astellas Pharma US, Inc.; Merck KGaA; and BioNTech SE. Pfizer Inc. was founded in 1849 and is headquartered in New York, New York.

Sangamo Therapeutics stock logo

Sangamo Therapeutics NASDAQ:SGMO

$0.82 -0.04 (-4.35%)
Closing price 04:00 PM Eastern
Extended Trading
$0.82 0.00 (-0.24%)
As of 07:55 PM Eastern
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Sangamo Therapeutics, Inc., a clinical-stage genomic medicine company, focuses on translating science into medicines that transform the lives of patients and families afflicted with serious diseases in the United States. The company's clinical-stage product candidates are ST-920, a gene therapy product candidate, which is in Phase 1/2 clinical study for the treatment of Fabry disease; TX200, a chimeric antigen receptor engineered regulatory T cell (CAR-Treg) therapy product candidate that is in Phase 1/2 clinical study for the prevention of immune-mediated rejection in HLA-A2 mismatched kidney transplantation; SB-525, a gene therapy product candidate, which is in Phase 3 clinical trial for the treatment of moderately severe to severe hemophilia A; BIVV003, a zinc finger nuclease gene-edited cell therapy product candidate that is in Phase 1/2 PRECIZN-1 clinical study for the treatment of sickle cell disease. Its preclinical development products focus on CAR-Treg cell therapies for autoimmune disorders and genome engineering for neurological diseases. Sangamo Therapeutics, Inc. has collaborative and strategic partnerships with Biogen MA, Inc.; Kite Pharma, Inc.; Pfizer Inc.; Sanofi S.A.; Novartis Institutes for BioMedical Research, Inc.; Shire International GmbH; Dow AgroSciences LLC; Sigma-Aldrich Corporation; Genentech, Inc.; Open Monoclonal Technology, Inc.; and California Institute for Regenerative Medicine. The company was formerly known as Sangamo BioSciences, Inc. and changed its name to Sangamo Therapeutics, Inc. in January 2017. Sangamo Therapeutics, Inc. was incorporated in 1995 and is headquartered in Richmond, California.

Vertex Pharmaceuticals stock logo

Vertex Pharmaceuticals NASDAQ:VRTX

$492.69 -9.86 (-1.96%)
Closing price 04:00 PM Eastern
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Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts.