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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:CRSPNASDAQ:EDITNASDAQ:NTLANYSE:NVSNASDAQ:REGNNASDAQ:VRTX On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCRSPCRISPR Therapeutics$40.89-4.1%$43.21$36.52▼$73.09$3.51B1.771.53 million shs1.64 million shsEDITEditas Medicine$1.30-6.5%$1.51$1.12▼$7.59$107.87M1.882.54 million shs1.37 million shsNTLAIntellia Therapeutics$8.73-6.2%$10.05$8.30▼$28.23$903.70M1.972.13 million shs3.86 million shsNVSNovartis$110.31-0.7%$107.12$92.35▼$120.92$225.47B0.531.47 million shs2.58 million shsREGNRegeneron Pharmaceuticals$634.14-4.1%$687.18$633.10▼$1,211.20$69.33B0.27637,643 shs852,346 shsVRTXVertex Pharmaceuticals$509.04-0.5%$471.81$377.85▼$519.88$130.72B0.411.22 million shs1.01 million shs(Almost) Everything You Need To Know About The EV MarketLooking to profit from the electric vehicle mega-trend? Enter your email address and we'll send you our list of which EV stocks show the most long-term potential.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCRSPCRISPR Therapeutics-4.06%-0.20%-14.65%-0.12%-42.47%EDITEditas Medicine-6.47%-1.14%-32.11%+7.44%-82.34%NTLAIntellia Therapeutics-6.23%-5.01%-28.27%-27.55%-67.46%NVSNovartis-0.75%-1.71%+0.82%+12.16%+15.23%REGNRegeneron Pharmaceuticals-4.06%-4.63%-9.45%-11.24%-34.02%VRTXVertex Pharmaceuticals-0.53%-0.62%+5.12%+24.71%+22.36%Remove AdsCompare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationCRSPCRISPR Therapeutics3.0372 of 5 stars4.21.00.00.02.13.30.6EDITEditas Medicine4.2683 of 5 stars3.04.00.04.32.41.71.3NTLAIntellia Therapeutics4.4787 of 5 stars4.31.00.04.71.82.51.3NVSNovartis2.4521 of 5 stars1.93.02.50.03.30.01.9REGNRegeneron Pharmaceuticals4.8603 of 5 stars4.43.01.72.34.11.71.9VRTXVertex Pharmaceuticals3.8652 of 5 stars2.33.00.03.33.02.51.3Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceCRSPCRISPR Therapeutics 2.48Hold$73.1178.79% UpsideEDITEditas Medicine 2.07Hold$6.83425.64% UpsideNTLAIntellia Therapeutics 2.63Moderate Buy$37.56330.19% UpsideNVSNovartis 1.80Reduce$123.3811.84% UpsideREGNRegeneron Pharmaceuticals 2.76Moderate Buy$973.1353.46% UpsideVRTXVertex Pharmaceuticals 2.65Moderate Buy$506.70-0.46% DownsideCurrent Analyst Ratings BreakdownLatest EDIT, NTLA, VRTX, CRSP, NVS, and REGN Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails3/5/2025NTLAIntellia TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageBuy$30.003/4/2025NTLAIntellia TherapeuticsTruist FinancialSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$90.00 ➝ $50.002/28/2025NTLAIntellia TherapeuticsBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$55.00 ➝ $26.002/28/2025NTLAIntellia TherapeuticsCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetNeutral ➝ Neutral$12.00 ➝ $14.002/28/2025NTLAIntellia TherapeuticsWells Fargo & CompanySubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$60.00 ➝ $50.002/28/2025NTLAIntellia TherapeuticsChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$91.00 ➝ $68.002/28/2025NTLAIntellia TherapeuticsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingNeutral ➝ Sell$9.002/28/2025NTLAIntellia TherapeuticsJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOverweight ➝ Neutral$45.00 ➝ $13.002/20/2025VRTXVertex PharmaceuticalsRoyal Bank of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetSector Perform ➝ Sector Perform$407.00 ➝ $408.002/19/2025CRSPCRISPR TherapeuticsCantor FitzgeraldSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingNeutral ➝ Neutral2/18/2025CRSPCRISPR TherapeuticsCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$89.00 ➝ $82.00(Data available from 3/26/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookCRSPCRISPR Therapeutics$35M100.21N/AN/A$22.52 per share1.82EDITEditas Medicine$32.31M3.34N/AN/A$4.27 per share0.30NTLAIntellia Therapeutics$57.88M15.61N/AN/A$11.73 per share0.74NVSNovartis$51.72B4.36$11.00 per share10.03$21.59 per share5.11REGNRegeneron Pharmaceuticals$14.20B4.88$41.64 per share15.23$268.50 per share2.36VRTXVertex Pharmaceuticals$11.02B11.86N/AN/A$63.90 per share7.97Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateCRSPCRISPR Therapeutics-$366.25M-$4.37N/AN/AN/A-981.54%-18.46%-15.79%5/6/2025 (Estimated)EDITEditas Medicine-$153.22M-$2.88N/AN/AN/A-340.96%-80.13%-50.99%5/6/2025 (Estimated)NTLAIntellia Therapeutics-$481.19M-$5.25N/AN/AN/AN/A-49.34%-40.27%5/8/2025 (Estimated)NVSNovartis$11.94B$5.8818.7612.521.7023.56%37.24%15.85%4/22/2025 (Estimated)REGNRegeneron Pharmaceuticals$4.41B$38.2816.5716.682.3431.07%16.32%12.76%5/1/2025 (Estimated)VRTXVertex Pharmaceuticals-$535.60M-$2.20N/A29.072.11-4.86%-2.02%-1.49%5/5/2025 (Estimated)Latest EDIT, NTLA, VRTX, CRSP, NVS, and REGN EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails4/22/2025N/ANVSNovartis$2.07N/AN/AN/AN/AN/A3/5/2025Q4 2024EDITEditas Medicine-$0.39-$0.55-$0.16-$0.55$37.17 million$30.60 million2/11/2025Q4 2024CRSPCRISPR Therapeutics-$1.15-$0.44+$0.71-$0.44N/AN/A2/10/2025Q4 2024VRTXVertex Pharmaceuticals$3.99$3.54-$0.45$3.50$2.78 billionN/A2/4/2025Q4 24REGNRegeneron Pharmaceuticals$11.21$12.07+$0.86$8.06$3.76 billion$3.79 billion1/31/2025Q4 2024NVSNovartis$1.80$1.98+$0.18$1.41$12.86 billionN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthCRSPCRISPR TherapeuticsN/AN/AN/AN/AN/AEDITEditas MedicineN/AN/AN/AN/AN/ANTLAIntellia TherapeuticsN/AN/AN/AN/AN/ANVSNovartis$2.512.28%+5.34%42.69%N/AREGNRegeneron Pharmaceuticals$0.880.14%N/A2.30%N/AVRTXVertex PharmaceuticalsN/AN/AN/AN/AN/ALatest EDIT, NTLA, VRTX, CRSP, NVS, and REGN DividendsAnnouncementCompanyPeriodAmountYieldEx-Dividend DateRecord DatePayable Date2/20/2025REGNRegeneron Pharmaceuticalsquarterly$0.880.53%2/20/20252/20/20253/20/20252/20/2025NVSNovartis$3.86953/12/20253/12/20253/12/2025(Data available from 1/1/2013 forward)Compare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioCRSPCRISPR TherapeuticsN/A22.0722.07EDITEditas MedicineN/A3.753.75NTLAIntellia TherapeuticsN/A6.736.73NVSNovartis0.481.040.84REGNRegeneron Pharmaceuticals0.094.733.95VRTXVertex Pharmaceuticals0.012.692.35Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipCRSPCRISPR Therapeutics69.20%EDITEditas Medicine71.90%NTLAIntellia Therapeutics88.77%NVSNovartis13.12%REGNRegeneron Pharmaceuticals83.31%VRTXVertex Pharmaceuticals90.96%Insider OwnershipCompanyInsider OwnershipCRSPCRISPR Therapeutics4.10%EDITEditas Medicine1.90%NTLAIntellia Therapeutics3.20%NVSNovartis0.01%REGNRegeneron Pharmaceuticals7.48%VRTXVertex Pharmaceuticals0.20%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableCRSPCRISPR Therapeutics47385.77 million82.26 millionOptionableEDITEditas Medicine23082.98 million80.98 millionOptionableNTLAIntellia Therapeutics600103.52 million98.59 millionOptionableNVSNovartis75,8832.04 billion2.04 billionOptionableREGNRegeneron Pharmaceuticals11,900109.33 million101.15 millionOptionableVRTXVertex Pharmaceuticals6,100256.79 million256.28 millionOptionableEDIT, NTLA, VRTX, CRSP, NVS, and REGN HeadlinesRecent News About These CompaniesVanguard Group Inc. Acquires 98,654 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 7:07 AM | marketbeat.comStevens Capital Management LP Makes New $829,000 Investment in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 6:41 AM | marketbeat.comSimplify Asset Management Inc. Acquires Shares of 4,689 Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 6:18 AM | marketbeat.comKLP Kapitalforvaltning AS Makes New $35.01 Million Investment in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 5:49 AM | marketbeat.comSei Investments Co. Acquires 61,234 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 5:33 AM | marketbeat.comAmerican Century Companies Inc. Lowers Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 5:33 AM | marketbeat.comSummit Global Investments Sells 813 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 5:09 AM | marketbeat.comWhittier Trust Co. Increases Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 24 at 4:50 AM | marketbeat.comJim Cramer on Vertex (VRTX): “A Revolutionary Anti-Pain Drug”March 23 at 12:34 PM | insidermonkey.comVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Acquired by Vestor Capital LLCMarch 23 at 6:24 AM | marketbeat.comMizuho Securities USA LLC Has $9.83 Million Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 23 at 6:23 AM | marketbeat.comCyrus J. Lawrence LLC Cuts Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 23 at 6:16 AM | marketbeat.comVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Purchased by Virtu Financial LLCMarch 23 at 6:09 AM | marketbeat.comVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Sold by Washington Trust BankMarch 23 at 5:41 AM | marketbeat.comTD Private Client Wealth LLC Sells 7,470 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 23 at 5:40 AM | marketbeat.comAxxcess Wealth Management LLC Has $424,000 Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 23 at 4:18 AM | marketbeat.comMadison Investment Advisors LLC Acquires New Stake in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 23 at 3:53 AM | marketbeat.comCommonwealth of Pennsylvania Public School Empls Retrmt SYS Sells 1,428 Shares of Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 22, 2025 | marketbeat.comTeacher Retirement System of Texas Has $42.24 Million Stock Holdings in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 22, 2025 | marketbeat.comSandy Spring Bank Has $1.92 Million Stock Position in Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX)March 22, 2025 | marketbeat.comVertex Pharmaceuticals Incorporated (NASDAQ:VRTX) Shares Bought by Vinva Investment Management LtdMarch 22, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeTop HeadlinesView All HeadlinesPrice Targets on NVIDIA Rise in Front of EarningsBy Sarah Horvath | February 24, 2025View Price Targets on NVIDIA Rise in Front of EarningsMediterranean Growth Monster: CAVA Keeps Surging—Buy the Dip?By Jea Yu | March 4, 2025View Mediterranean Growth Monster: CAVA Keeps Surging—Buy the Dip?Retail Sales Data Signals a Surge: The E-Commerce Stock PicksBy Gabriel Osorio-Mazilli | March 19, 2025View Retail Sales Data Signals a Surge: The E-Commerce Stock PicksRegeneron: Is It the Perfect Biotech Stock for Value and Growth?By Jea Yu | February 27, 2025View Regeneron: Is It the Perfect Biotech Stock for Value and Growth?3 Stocks That Could Win Big From a 10% Cap on Credit Card RatesBy Jea Yu | March 19, 2025View 3 Stocks That Could Win Big From a 10% Cap on Credit Card RatesEDIT, NTLA, VRTX, CRSP, NVS, and REGN Company DescriptionsCRISPR Therapeutics NASDAQ:CRSP$40.89 -1.73 (-4.06%) Closing price 03/25/2025 04:00 PM EasternExtended Trading$41.04 +0.15 (+0.37%) As of 03/25/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.CRISPR Therapeutics is a gene-editing company focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. CRISPR/Cas9 is a revolutionary gene-editing technology that allows for precise, directed changes to genomic DNA. CRISPR Therapeutics has established a portfolio of therapeutic programs across a broad range of disease areas including hemoglobinopathies, oncology, regenerative medicine and rare diseases. To accelerate and expand its efforts, CRISPR Therapeutics has established strategic collaborations with companies including Bayer, Vertex Pharmaceuticals and ViaCyte, Inc. CRISPR Therapeutics AG is headquartered in Zug, Switzerland, with its wholly-owned U.S. subsidiary, CRISPR Therapeutics, Inc., and R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California and London, United Kingdom. For more information, please visit www.crisprtx.com.Editas Medicine NASDAQ:EDIT$1.30 -0.09 (-6.47%) Closing price 03/25/2025 04:00 PM EasternExtended Trading$1.30 +0.00 (+0.38%) As of 03/25/2025 07:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Editas Medicine, Inc., a clinical stage genome editing company, focuses on developing transformative genomic medicines to treat a range of serious diseases. It develops a proprietary gene editing platform based on CRISPR technology. The company develops EDIT-101, which is in Phase 1/2 BRILLIANCE trial for Leber Congenital Amaurosis; and reni-cel, a clinical development gene-edited medicine to treat sickle cell disease and transfusion-dependent beta-thalassemia. In addition, the company is developing alpha-beta T cells for solid and liquid tumors; and gamma delta T cell therapies to treat cancer. It has a research collaboration with Juno Therapeutics, Inc. to develop engineered T cells for cancer; strategic alliance and option agreement with Allergan Pharmaceuticals International Limited. The company was formerly known as Gengine, Inc. and changed its name to Editas Medicine, Inc. in November 2013. Editas Medicine, Inc. was incorporated in 2013 and is based in Cambridge, Massachusetts.Intellia Therapeutics NASDAQ:NTLA$8.73 -0.58 (-6.23%) Closing price 03/25/2025 04:00 PM EasternExtended Trading$8.74 +0.01 (+0.10%) As of 03/25/2025 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Intellia Therapeutics, Inc., a genome editing company, focuses on the development of curative therapeutics. The company's in vivo programs include NTLA-2001, which is in Phase 1 clinical trial for the treatment of transthyretin amyloidosis; NTLA-2002 for the treatment of hereditary angioedema; and NTLA-3001 for alpha-1 antitrypsin deficiency associated lung disease. It also focusses on programs comprising hemophilia A and hemophilia B; and research of proprietary programs focused on developing engineered cell therapies to treat various cancers and autoimmune diseases. In addition, the company offers tools comprising of Clustered, Regularly Interspaced Short Palindromic Repeats/CRISPR associated 9 (CRISPR/Cas9) system. It has license and collaboration agreement with Regeneron Pharmaceuticals, Inc. to co-develop potential products for the treatment of hemophilia A and hemophilia B; AvenCell Therapeutics, Inc. to develop allogeneic universal CAR-T cell therapies, and co-develop and co-commercialize allogeneic universal CAR-T cell products for an immuno-oncology indication; SparingVision SAS to develop novel genomic medicines utilizing CRISPR/Cas9 technology for the treatment of ocular diseases; Kyverna Therapeutics, Inc. for the development of an allogeneic CD19 CAR-T cell therapy for the treatment of a variety of B cell-mediated autoimmune diseases; and ONK Therapeutics, Ltd. for the development of engineered NK cell therapies to cure patients with cancer. Intellia Therapeutics, Inc. was incorporated in 2014 and is headquartered in Cambridge, Massachusetts.Novartis NYSE:NVS$110.31 -0.78 (-0.70%) Closing price 03/25/2025 03:58 PM EasternExtended Trading$110.83 +0.52 (+0.47%) As of 03/25/2025 07:27 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Novartis AG engages in the research, development, manufacture, and marketing of healthcare products in Switzerland and internationally. The company offers prescription medicines for patients and physicians. It focuses on therapeutic areas, such as cardiovascular, renal and metabolic, immunology, neuroscience, and oncology, as well as ophthalmology and hematology. Novartis AG has a license and collaboration agreement with Alnylam Pharmaceuticals to develop, manufacture, and commercialize inclisiran, a therapy to reduce LDL cholesterol; and Dawn Health for the development and commercialization of Ekiva, a digital solution designed for people living with Paroxysmal Nocturnal Hemoglobinuria. The company was incorporated in 1996 and is headquartered in Basel, Switzerland.Regeneron Pharmaceuticals NASDAQ:REGN$634.14 -26.86 (-4.06%) Closing price 03/25/2025 04:00 PM EasternExtended Trading$635.49 +1.35 (+0.21%) As of 03/25/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various diseases worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular edema; myopic choroidal neovascularization; diabetic retinopathy; neovascular glaucoma; and retinopathy of prematurity. It also provides Dupixent injection to treat atopic dermatitis and asthma in adults and pediatrics; Libtayo injection to treat metastatic or locally advanced cutaneous squamous cell carcinoma; Praluent injection for heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in adults; REGEN-COV for covid-19; and Kevzara solution for treating rheumatoid arthritis in adults. In addition, the company offers Inmazeb injection for infection caused by Zaire ebolavirus; ARCALYST injection for cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome and muckle-wells syndrome; and ZALTRAP injection for intravenous infusion to treat metastatic colorectal cancer; and develops product candidates for treating patients with eye, allergic and inflammatory, cardiovascular and metabolic, infectious, and rare diseases; and cancer, pain, and hematologic conditions. It has collaboration with Mammoth Biosciences, Inc. to research, develop and commercialize in vivo CRISPR-based gene editing therapies for multiple tissues and cell types. The company was incorporated in 1988 and is headquartered in Tarrytown, New York.Vertex Pharmaceuticals NASDAQ:VRTX$509.04 -2.70 (-0.53%) Closing price 03/25/2025 04:00 PM EasternExtended Trading$512.71 +3.67 (+0.72%) As of 03/25/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age or older; SYMDEKO/SYMKEVI for people with CF for 6 years of age or older; ORKAMBI for CF patients 1 year or older; and KALYDECO for the treatment of patients with 1 year or older who have CF with ivacaftor. The company's pipeline includes VX-522, a CFTR mRNA therapeutic designed to treat the underlying cause of CF, which is in Phase 1 clinical trial; VX-548, a non-opioid medicine for the treatment of acute and neuropathic pain which is in Phase 3 clinical trial; Exa-cel, for the treatment of sickle cell disease and transfusion-dependent beta thalassemia which is in Phase 2/3 clinical trial. In addition, it provides inaxaplin for the treatment of APOL1-mediated focal segmental glomerulosclerosis and co-morbidities, such as hypertension which is in single Phase 2/3; VX- 880 and VX-264, treatment for Type 1 Diabetes which is in Phase 1/2 clinical trial; VX-970, which is in Phase 2 clinical trial for the treatment of cancer; and VX-803 and VX-984 for treatment of cancer in Phase 1 clinical trial. Further, it sells the products to specialty pharmacy and specialty distributors in the United States, as well as retail pharmacies, hospitals, and clinics. Additionally, the company has collaborations with CRISPR Therapeutics AG.; Moderna, Inc.; Entrada Therapeutics, Inc.; Arbor Biotechnologies, Inc.; Mammoth Biosciences, Inc.; and Verve Therapeutics., as well as collaborations with Tevard Biosciences to develop novel tRNA-based therapies for duchenne muscular dystrophy. Vertex Pharmaceuticals Incorporated was founded in 1989 and is headquartered in Boston, Massachusetts. 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