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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:AVDL NASDAQ:AVXL NASDAQ:ESPR NYSE:RCUS On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAVDLAvadel Pharmaceuticals$10.65+2.6%$9.36$6.38▼$17.30$1.00B1.421.23 million shs1.64 million shsAVXLAnavex Life Sciences$11.26+3.6%$8.88$4.93▼$14.44$928.48M0.721.19 million shs1.17 million shsESPREsperion Therapeutics$1.12-0.9%$1.02$0.69▼$3.94$223.96M0.74.70 million shs2.20 million shsRCUSArcus Biosciences$9.26+2.6%$8.93$6.50▼$18.98$956.14M0.8885,670 shs494,341 shsThe 10 Best AI Stocks to Own in 2025Wondering where to start (or end) with AI stocks? These 10 simple stocks can help investors build long-term wealth as artificial intelligence continues to grow into the future.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAVDLAvadel Pharmaceuticals+2.60%+11.52%+12.11%+32.63%-37.02%AVXLAnavex Life Sciences+3.59%+4.65%+30.78%+25.81%+93.14%ESPREsperion Therapeutics-0.88%-8.94%-4.27%+17.89%-58.97%RCUSArcus Biosciences+2.56%-0.53%+1.97%+17.45%-41.72%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAVDLAvadel Pharmaceuticals1.8551 of 5 stars3.51.00.00.01.61.70.6AVXLAnavex Life Sciences3.9885 of 5 stars3.71.00.04.73.10.80.6ESPREsperion Therapeutics3.9398 of 5 stars3.42.00.03.92.51.70.6RCUSArcus Biosciences2.3103 of 5 stars4.41.00.00.01.61.70.0Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAVDLAvadel Pharmaceuticals 3.00Buy$18.1770.58% UpsideAVXLAnavex Life Sciences 3.33Buy$44.00290.76% UpsideESPREsperion Therapeutics 2.80Moderate Buy$7.00525.00% UpsideRCUSArcus Biosciences 2.89Moderate Buy$21.29129.84% UpsideCurrent Analyst Ratings BreakdownLatest ESPR, RCUS, AVDL, and AVXL Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails6/17/2025ESPREsperion TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$16.005/9/2025RCUSArcus BiosciencesMorgan StanleySubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$24.00 ➝ $22.005/8/2025AVDLAvadel PharmaceuticalsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$19.00 ➝ $19.005/8/2025RCUSArcus BiosciencesThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$15.00 ➝ $13.005/7/2025ESPREsperion TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$5.00 ➝ $4.005/7/2025RCUSArcus BiosciencesWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform$33.005/7/2025RCUSArcus BiosciencesWells Fargo & CompanySubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$29.00 ➝ $26.004/25/2025ESPREsperion TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$5.00 ➝ $5.004/25/2025ESPREsperion TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$16.00 ➝ $16.004/23/2025RCUSArcus BiosciencesBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$29.00 ➝ $14.004/17/2025ESPREsperion TherapeuticsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetNeutral ➝ Neutral$4.00 ➝ $3.00(Data available from 7/17/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAVDLAvadel Pharmaceuticals$169.12M6.09N/AN/A$0.77 per share13.83AVXLAnavex Life SciencesN/AN/AN/AN/A$1.42 per shareN/AESPREsperion Therapeutics$332.31M0.67$0.02 per share47.03($1.97) per share-0.57RCUSArcus Biosciences$258M3.80N/AN/A$5.30 per share1.75Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAVDLAvadel Pharmaceuticals-$48.83M-$0.27N/A177.50N/A-13.58%-36.07%-16.30%8/6/2025 (Estimated)AVXLAnavex Life Sciences-$43M-$0.55N/AN/AN/AN/A-40.93%-36.38%8/5/2025 (Estimated)ESPREsperion Therapeutics-$51.74M-$0.80N/AN/AN/A-59.03%-0.91%-29.47%8/11/2025 (Estimated)RCUSArcus Biosciences-$283M-$4.19N/AN/AN/A-258.94%-70.58%-32.97%8/4/2025 (Estimated)Latest ESPR, RCUS, AVDL, and AVXL EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/11/2025Q2 2025ESPREsperion Therapeutics-$0.17N/AN/AN/A$62.55 millionN/A8/5/2025Q3 2025AVXLAnavex Life Sciences-$0.13N/AN/AN/AN/AN/A5/13/2025Q2 2025AVXLAnavex Life Sciences-$0.16-$0.13+$0.03-$0.13N/AN/A5/7/2025Q1 2025AVDLAvadel Pharmaceuticals-$0.07-$0.05+$0.02-$0.05$50.57 million$52.51 million5/6/2025Q1 2025ESPREsperion Therapeutics-$0.18-$0.21-$0.03-$0.21$54.97 million$65.00 million5/6/2025Q1 2025RCUSArcus Biosciences-$1.02-$1.14-$0.12-$1.14$38.61 million$28.00 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAVDLAvadel PharmaceuticalsN/AN/AN/AN/AN/AAVXLAnavex Life SciencesN/AN/AN/AN/AN/AESPREsperion TherapeuticsN/AN/AN/AN/AN/ARCUSArcus BiosciencesN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAVDLAvadel PharmaceuticalsN/A2.732.33AVXLAnavex Life SciencesN/A6.746.74ESPREsperion TherapeuticsN/A1.180.81RCUSArcus Biosciences0.095.375.37Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAVDLAvadel Pharmaceuticals69.19%AVXLAnavex Life Sciences31.55%ESPREsperion Therapeutics47.39%RCUSArcus Biosciences92.89%Insider OwnershipCompanyInsider OwnershipAVDLAvadel Pharmaceuticals5.20%AVXLAnavex Life Sciences11.40%ESPREsperion Therapeutics1.70%RCUSArcus Biosciences9.60%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAVDLAvadel Pharmaceuticals7096.74 million91.71 millionOptionableAVXLAnavex Life Sciences4085.42 million75.64 millionOptionableESPREsperion Therapeutics200198.20 million194.83 millionOptionableRCUSArcus Biosciences500105.89 million95.72 millionOptionableESPR, RCUS, AVDL, and AVXL HeadlinesRecent News About These CompaniesArcus Biosciences (NYSE:RCUS) Shares Down 4.6% - Here's What HappenedJuly 15 at 2:44 PM | marketbeat.comArcus Biosciences’ quemliclustat receives US FDA orphan drug designation to treat pancreatic cancerJuly 15 at 10:59 AM | pharmabiz.comPArcus Biosciences' Quemliclustat Gets Orphan Drug Status For ... - NasdaqJuly 12, 2025 | nasdaq.comArcus Biosciences’ cancer drug gets orphan drug statusJuly 11, 2025 | msn.comArcus’ Quemliclustat Earns Orphan Drug Designation as Phase III Pancreatic Cancer Trial AdvancesJuly 11, 2025 | appliedclinicaltrialsonline.comAArcus’ Quemliclustat Receives Orphan Drug DesignationJuly 11, 2025 | contractpharma.comCArcus Biosciences' Pancreatic Cancer Treatment Gets Orphan Drug StatusJuly 11, 2025 | marketwatch.comArcus Biosciences’ Quemliclustat Receives Orphan Drug Designation for Pancreatic CancerJuly 11, 2025 | finance.yahoo.comArcus Biosciences (NYSE:RCUS) Shares Gap Up - Here's WhyJuly 10, 2025 | marketbeat.comArcus Biosciences' Quemliclustat Receives Orphan Drug Designation for Pancreatic CancerJuly 10, 2025 | gurufocus.comArcus Biosciences (NYSE:RCUS) Stock Price Up 8.1% - Should You Buy?July 9, 2025 | marketbeat.comArcus Biosciences Announces New Employment Inducement GrantsJuly 9, 2025 | businesswire.comArcus Biosciences (NYSE:RCUS) Trading Down 2.9% - Here's What HappenedJuly 3, 2025 | marketbeat.comArcus Biosciences Presents First Postive Data for Oral Metastatic Kidney Cancer TreatmentJuly 1, 2025 | msn.comArcus Biosciences (NYSE:RCUS) Trading Down 6.3% - Here's What HappenedJune 27, 2025 | marketbeat.comIncyte, FDA, Sun Pharma and more—Chutes & LaddersJune 27, 2025 | fiercebiotech.comFArcus Biosciences Announces New Employment Inducement Grants - Business WireJune 26, 2025 | businesswire.comPrecision Bio's DMD Therapy Gets Rare Pediatric Status, But Stock Slides; Retail Crowd Sees ‘Good Risk-Reward’June 26, 2025 | msn.comPrecision BioSciences Shares Surge Following FDA Rare Pediatric Disease DesignationJune 25, 2025 | msn.comPrecision BioSciences gets FDA rare disease status for DMD treatment, stock jumps 10%June 25, 2025 | msn.comArcus Biosciences, Inc. (RCUS) Cash Flow - Yahoo FinanceJune 24, 2025 | finance.yahoo.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimeESPR, RCUS, AVDL, and AVXL Company DescriptionsAvadel Pharmaceuticals NASDAQ:AVDL$10.65 +0.27 (+2.60%) Closing price 07/16/2025 04:00 PM EasternExtended Trading$10.64 -0.01 (-0.05%) As of 07/16/2025 04:48 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Avadel Pharmaceuticals plc operates as a biopharmaceutical company in the United States. Its lead product candidate is LUMRYZ, a formulation of sodium oxybate, which is in a Phase 3 clinical trial for the treatment of excessive daytime sleepiness or cataplexy in adults with narcolepsy. The company was formerly known as Flamel Technologies SA and changed its name to Avadel Pharmaceuticals plc in January 2017. Avadel Pharmaceuticals plc was incorporated in 2015 and is headquartered in Dublin, Ireland.Anavex Life Sciences NASDAQ:AVXL$11.26 +0.39 (+3.59%) Closing price 07/16/2025 04:00 PM EasternExtended Trading$11.21 -0.05 (-0.44%) As of 07/16/2025 07:47 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Anavex Life Sciences Corp., a clinical stage biopharmaceutical company, engages in the development of therapeutics for the treatment of central nervous system diseases. Its lead product candidate is ANAVEX 2-73 for the treatment of Alzheimer's disease and Parkinson's disease, as well as other central nervous system diseases, including rare diseases, such as Rett syndrome, a rare severe neurological monogenic disorder; and infantile spasms, Fragile X syndrome, and Angelman syndrome. The company's drug candidate also comprises ANAVEX 3-71, which is in clinical trial for the treatment of schizophrenia, frontotemporal dementia, and Alzheimer's disease. Its preclinical drug candidates include ANAVEX 1-41 for the treatment of depression, stroke, and neurogenerative disease; ANAVEX 1066 for the potential treatment of neuropathic and visceral pain; and ANAVEX 1037 to treat prostate and pancreatic cancer. The company was incorporated in 2004 and is headquartered in New York, New York.Esperion Therapeutics NASDAQ:ESPR$1.12 -0.01 (-0.88%) Closing price 07/16/2025 04:00 PM EasternExtended Trading$1.13 +0.01 (+0.89%) As of 07/16/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Esperion Therapeutics, Inc., a pharmaceutical company, develops and commercializes medicines for the treatment of patients with elevated low density lipoprotein cholesterol (LDL-C). Its marketed products include NEXLETOL (bempedoic acid) and NEXLIZET (bempedoic acid and ezetimibe) tablets that are oral, once-daily, non-statin medicines for the treatment of primary hyperlipidemia in adults with heterozygous familial hypercholesterolemia or atherosclerotic cardiovascular disease who require additional lowering of LDL-C. The company's products also include NILEMDO, an ATP Citrate Lyase (ACL) inhibitor that lowers LDL-C and cardiovascular risk by reducing cholesterol biosynthesis and up-regulating the LDL receptors; and NUSTENDI, a bempedoic acid and ezetimibe tablet to treat elevated LDL-C. The company has license and collaboration agreements with Daiichi Sankyo Co. Ltd to; Otsuka Pharmaceutical Co., Ltd; and Daiichi Sankyo Europe GmbH. Esperion Therapeutics, Inc. was incorporated in 2008 and is headquartered in Ann Arbor, Michigan.Arcus Biosciences NYSE:RCUS$9.26 +0.23 (+2.56%) Closing price 07/16/2025 03:59 PM EasternExtended Trading$9.26 -0.01 (-0.06%) As of 07/16/2025 06:16 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States. The company's pipeline products include Domvanalimab, an anti-TIGIT antibody, which is in Phase 2 and Phase 3 clinical trial; and AB308, an investigational anti-TIGIT monoclonal antibody, which is in Phase 1b clinical trial to study people with advanced solid and hematologic malignancies. It also develops Etrumadenant, a dual A2a/A2b adenosine receptor antagonist, which is in Phase 2 clinical trial; Quemliclustat, a small-molecule CD73 inhibitor, which is Phase 1b and Phase 2 clinical trial; Zimberelimab, an anti-PD-1 antibody, which is in Phase 2 clinical trial for metastatic cell lung cancer and monotherapy; and AB521, an oral and small-molecule inhibitor of HIF-2a, which is in Phase 1 clinical trial for the treatment of Von Hippel-Lindau disease. In addition, the company's preclinical pipeline products include AB598, a CD39 antibody; and AB801, a small molecule Axl inhibitor. It has a clinical collaboration with AstraZeneca to evaluate domvanalimab in combination with durvalumab in a registrational phase 3 clinical trial in patients with unresectable Stage 3 NSCLC; and BVF Partners L.P. to support the discovery and development of compounds for the treatment of inflammatory diseases. Arcus Biosciences, Inc. was incorporated in 2015 and is headquartered in Hayward, California. 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