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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
ALLO Allogene Therapeutics	$1.13 -4.2%	$1.20	$0.86 ▼ $3.78	$250.73M	0.35	5.62 million shs	3.34 million shs
GANX Gain Therapeutics	$1.99 +5.9%	$1.69	$0.95 ▼ $3.19	$71.54M	0.1	372,770 shs	599,362 shs
PBYI Puma Biotechnology	$5.04 +1.4%	$3.91	$2.22 ▼ $6.07	$253.87M	1.3	966,558 shs	377,539 shs
TVRD Tvardi Therapeutics	$29.92 -1.2%	$25.42	$8.13 ▼ $34.31	$280.57M	0.21	23,176 shs	14,257 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
ALLO Allogene Therapeutics	0.00%	-5.04%	-8.13%	-3.00%	-56.03%
GANX Gain Therapeutics	0.00%	+1.02%	+36.30%	+12.11%	+49.62%
PBYI Puma Biotechnology	0.00%	-4.00%	+62.06%	+51.35%	+105.71%
TVRD Tvardi Therapeutics	0.00%	+6.67%	+15.25%	+3.17%	+2,991,999,900.00%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
ALLO Allogene Therapeutics	2.7897 of 5 stars	3.4	3.0	2.5	2.5	0.6
GANX Gain Therapeutics	2.141 of 5 stars	3.5	3.0	2.3	0.0	0.6
PBYI Puma Biotechnology	4.0598 of 5 stars	3.5	1.0	3.1	4.2	3.1
TVRD Tvardi Therapeutics	1.7616 of 5 stars	3.5	0.0	2.9	0.8	0.0

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
ALLO Allogene Therapeutics	2.75	Moderate Buy	$8.44	647.30% Upside
GANX Gain Therapeutics	3.00	Buy	$7.80	291.96% Upside
PBYI Puma Biotechnology	3.00	Buy	$7.00	38.89% Upside
TVRD Tvardi Therapeutics	3.00	Buy	$64.25	114.74% Upside

Current Analyst Ratings Breakdown

Latest GANX, PBYI, ALLO, and TVRD Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
8/13/2025	GANX Gain Therapeutics	Roth Capital Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Buy ➝ Buy	$7.00 ➝ $6.00
8/4/2025	ALLO Allogene Therapeutics	JMP Securities Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Market Perform ➝ Market Perform
8/4/2025	ALLO Allogene Therapeutics	JPMorgan Chase & Co. Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Overweight ➝ Neutral
7/14/2025	TVRD Tvardi Therapeutics	Raymond James Financial Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Outperform	$62.00
7/11/2025	TVRD Tvardi Therapeutics	Cantor Fitzgerald Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Overweight	$52.00
7/3/2025	GANX Gain Therapeutics	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$8.00
6/12/2025	TVRD Tvardi Therapeutics	Piper Sandler Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Overweight	$78.00

(Data available from 8/31/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
ALLO Allogene Therapeutics	$20K	12,536.22	N/A	N/A	$1.55 per share	0.73
GANX Gain Therapeutics	$50K	1,430.81	N/A	N/A	$0.10 per share	19.90
PBYI Puma Biotechnology	$238.06M	1.07	$0.85 per share	5.92	$2.08 per share	2.42
TVRD Tvardi Therapeutics	$7.14M	39.31	N/A	N/A	$3.51 per share	8.52

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
ALLO Allogene Therapeutics	-$257.59M	-$1.11	N/A	N/A	N/A	N/A	-55.99%	-42.75%	11/6/2025 (Estimated)
GANX Gain Therapeutics	-$20.41M	-$0.63	N/A	N/A	N/A	N/A	-289.10%	-155.11%	11/13/2025 (Estimated)
PBYI Puma Biotechnology	$30.28M	$0.98	5.14	13.26	N/A	20.38%	53.15%	23.51%	11/6/2025 (Estimated)
TVRD Tvardi Therapeutics	-$70.87M	N/A	0.00	∞	N/A	-678.79%	-565.83%	-66.71%	N/A

Latest GANX, PBYI, ALLO, and TVRD Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/14/2025	Q2 2025	TVRD Tvardi Therapeutics	-$0.51	-$1.00	-$0.49	-$1.00	N/A	N/A
8/13/2025	Q2 2025	ALLO Allogene Therapeutics	-$0.28	-$0.23	+$0.05	-$0.23	N/A	N/A
8/12/2025	Q2 2025	GANX Gain Therapeutics	-$0.17	-$0.19	-$0.02	-$0.19	N/A	N/A

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
ALLO Allogene Therapeutics	N/A	N/A	N/A	N/A	N/A
GANX Gain Therapeutics	N/A	N/A	N/A	N/A	N/A
PBYI Puma Biotechnology	N/A	N/A	N/A	N/A	N/A
TVRD Tvardi Therapeutics	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
ALLO Allogene Therapeutics	N/A	8.92	8.92
GANX Gain Therapeutics	0.09	1.79	1.79
PBYI Puma Biotechnology	0.10	1.73	1.62
TVRD Tvardi Therapeutics	N/A	4.04	4.04

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
ALLO Allogene Therapeutics	83.63%
GANX Gain Therapeutics	11.97%
PBYI Puma Biotechnology	61.29%
TVRD Tvardi Therapeutics	44.66%

Insider Ownership

Company	Insider Ownership
ALLO Allogene Therapeutics	13.20%
GANX Gain Therapeutics	7.18%
PBYI Puma Biotechnology	23.30%
TVRD Tvardi Therapeutics	3.10%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
ALLO Allogene Therapeutics	310	221.88 million	192.59 million	Optionable
GANX Gain Therapeutics	20	35.95 million	33.37 million	Optionable
PBYI Puma Biotechnology	200	50.37 million	38.64 million	Optionable
TVRD Tvardi Therapeutics	80	9.38 million	9.09 million	N/A

GANX, PBYI, ALLO, and TVRD Headlines

Recent News About These Companies

Tvardi Therapeutics (NASDAQ:TVRD) Is In A Good Position To Deliver On Growth Plans

August 31 at 10:04 AM | finance.yahoo.com

Tvardi Therapeutics (NASDAQ:TVRD) Trading Down 0.9% - Here's Why

August 24, 2025 | marketbeat.com

Tvardi Therapeutics to Participate in the Cantor Global Healthcare Conference

August 21, 2025 | theglobeandmail.com

Tvardi Therapeutics (NASDAQ:TVRD) Releases Quarterly Earnings Results, Misses Estimates By $0.49 EPS

August 16, 2025 | marketbeat.com

Tvardi Therapeutics expects cash to fund operations into Q4 2026

August 15, 2025 | msn.com

Tvardi Therapeutics reports Q2 EPS ($1.00) vs ($2.71) last year

August 15, 2025 | msn.com

Tvardi: Q2 Earnings Snapshot

August 14, 2025 | timesunion.comT

Tvardi Therapeutics Announces Second Quarter 2025 Results and Provides Business Update

August 14, 2025 | finance.yahoo.com

Raymond James Initiates Coverage of Tvardi Therapeutics (TVRD) with Outperform Recommendation

July 15, 2025 | msn.com

Tvardi Therapeutics to Participate in the BTIG Virtual Biotechnology Conference

July 15, 2025 | finance.yahoo.com

Tvardi Therapeutics to Participate in the BTIG Virtual Biotechnology Conference

July 15, 2025 | businesswire.com

Cantor Fitzgerald Initiates Coverage of Tvardi Therapeutics (TVRD) with Overweight Recommendation

July 12, 2025 | msn.com

Tvardi Therapeutics Inc News (TVRD) - Investing.com

June 27, 2025 | investing.com

TVRD Tvardi Therapeutics, Inc.

June 19, 2025 | seekingalpha.com

Piper Sandler initiates Tvardi Therapeutics stock with overweight rating

June 13, 2025 | uk.investing.com

Recently Listed Tvardi Therapeutics' Lead Drug 'Positioned To Drive Broad Improvement', Analyst Sees Over 150% Stock Upside

June 12, 2025 | benzinga.com

Tvardi Therapeutics Inc (TVRD)

June 7, 2025 | investing.com

Tvardi Therapeutics Announces Completion of Enrollment in Phase 2 Clinical Trial of TTI-101 in Idiopathic Pulmonary Fibrosis

May 27, 2025 | businesswire.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

Top Headlines

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GANX, PBYI, ALLO, and TVRD Company Descriptions

Allogene Therapeutics NASDAQ:ALLO

$1.13 -0.05 (-4.24%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$1.14 +0.01 (+1.24%)

As of 08/29/2025 07:18 PM Eastern

Allogene Therapeutics, Inc., a clinical stage immuno-oncology company, develops and commercializes genetically engineered allogeneic T cell therapies for the treatment of cancer. It develops, manufactures, and commercializes UCART19, an allogeneic chimeric antigen receptor (CAR) T cell product candidate for the treatment of pediatric and adult patients with R/R CD19 positive B-cell acute lymphoblastic leukemia (ALL). The company also develops cemacabtagene ansegedleucel, an engineered allogeneic CAR T cell product candidate that targets CD19 for the treatment of large B-cell lymphoma; and is in Phase 1b clinical trial for the treatment of chronic lymphocytic leukemia. In addition, it is developing ALLO-715, an allogeneic CAR T cell product candidate that is in a Phase 1 clinical trial for treating R/R multiple myeloma; ALLO-605, an allogeneic CAR T cell product candidate that is in a Phase I clinical trial for the treatment of multiple myeloma; ALLO-647, an anti-CD52 monoclonal antibody; CD70 to treat renal cell cancer; ALLO-316, an allogeneic CAR T cell product candidate that is in Phase 1 clinical trial for the treatment of advanced or metastatic RCC; ALLO-329 for the treatment of certain autoimmune diseases; DLL3 for the treatment of small cell lung cancer and other aggressive neuroendocrine tumors; and Claudin 18.2 for the treatment of gastric and pancreatic cancer. The company has license and collaboration agreements with Pfizer Inc.; Servier; Cellectis S.A.; and Notch Therapeutics Inc. It also has a strategic collaboration agreement with The University of Texas MD Anderson Cancer Center for the preclinical and clinical investigation of allogeneic CAR T cell product candidates; and a strategic partnership with Foresight Diagnostics to develop MRD-based In-Vitro Diagnostic for use in ALPHA3. The company was incorporated in 2017 and is headquartered in South San Francisco, California.

Gain Therapeutics NASDAQ:GANX

$1.99 +0.11 (+5.85%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$2.01 +0.02 (+1.21%)

As of 08/29/2025 08:00 PM Eastern

Gain Therapeutics, Inc., a biotechnology company, develops novel small molecule therapeutics to treat diseases across various therapeutic areas. Its drug discovery platform Magellan discovers novel allosteric binding sites in a disease; identifies proprietary small molecules that bind these sites to modulate protein function; and treats the underlying cause of the disease. The company's lead drug candidate, GT-02287 for the treatment of GBA1 Parkinson's disease is being evaluated in a Phase I clinical trials. It also has various small molecule drug candidates, which are in the discovery, research, and preclinical stages for the treatment of Dementia with Lewy Bodies, Alzhiemer's Disease, Gaucher, GM1 Gangliosidosis, Krabbe Disease, Alpha1-Antitrypsun deficiency, and solid tumors. Gain Therapeutics, Inc. was founded in 2017 and is headquartered in Bethesda, Maryland.

Puma Biotechnology NASDAQ:PBYI

$5.04 +0.07 (+1.41%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$4.96 -0.09 (-1.69%)

As of 08/29/2025 07:25 PM Eastern

Puma Biotechnology, Inc., a biopharmaceutical company, focuses on the development and commercialization of products to enhance cancer care in the United States and internationally. The company offers NERLYNX, an oral version of neratinib that is used to treat adult patients with early stage HER2-overexpressed/amplified breast cancer; and advanced or metastatic HER2-positive breast cancer when combined with capecitabine. It also develops alisertib, a small molecule inhibitor of aurora kinase A for the treatment of hormone receptor positive breast cancer, triple negative breast cancer, small cell lung cancer, and head and neck cancer. The company sells its products through specialty pharmacy and distributor networks. It has license agreements with Pfizer Inc. for the development, manufacture, and commercialization of neratinib (oral), neratinib (intravenous), PB357, and related compounds; and Takeda Pharmaceutical Company Limited for the research, development, and commercialization of alisertib, as well as sub-license agreements with Specialised Therapeutics Asia Pte Ltd., Medison Pharma Ltd., Pint Pharma International SA, Knight Therapeutics, Inc., Pierre Fabre Medicament SAS, and Bixink Therapeutics Co., Ltd. The company was founded in 2010 and is headquartered in Los Angeles, California.

Tvardi Therapeutics NASDAQ:TVRD

$29.92 -0.35 (-1.16%)

As of 08/29/2025 04:00 PM Eastern

Cara Therapeutics, Inc., an early commercial-stage biopharmaceutical company, focuses on developing and commercializing chemical entities with a primary focus on pruritus and pain by selectively targeting kappa opioid receptors in the United States. The company is developing product candidates that target the body's peripheral nervous system and immune cells. The company's lead product is KORSUVA (difelikefalin) injection for the treatment of moderate-to-severe pruritus associated with chronic kidney disease (CKD) in adults undergoing hemodialysis. Its product candidate includes Oral KORSUVA (difelikefalin), which has completed Phase II clinical trial to treat pruritus atopic dermatitis and pruritus non-dialysis-dependent chronic kidney disease (NDD-CKD) associated pruritus; and in Phase II clinical trial to treat pruritus chronic liver disease (CLD) primary biliary cholangitis (PBC) and notalgia paresthetica. The company has license agreements with Maruishi Pharmaceutical Co., Ltd to develop, manufacture, and commercialize drug products containing difelikefalin for acute pain and uremic pruritus in Japan; and Chong Kun Dang Pharmaceutical Corporation to develop, manufacture, and commercialize drug products containing difelikefalin in South Korea. Cara Therapeutics, Inc. was incorporated in 2004 and is based in Stamford, Connecticut.

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Comparative Price Performance Over Time