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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:HUMA NASDAQ:IOVA NASDAQ:ORIC NASDAQ:UPB On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeHUMAHumacyte$1.55-1.9%$2.14$1.15▼$6.77$245.48M1.885.91 million shs2.38 million shsIOVAIovance Biotherapeutics$2.23$2.34$1.64▼$12.51$806.93M0.8214.88 million shs7.02 million shsORICOric Pharmaceuticals$10.23+2.0%$10.38$3.90▼$14.67$993.57M1.63752,096 shs711,532 shsUPBUpstream Bio$17.13+2.2%$13.96$5.14▼$29.46$923.47MN/A427,216 shs305,698 shs The Best Nuclear Energy Stocks to BuyNuclear energy stocks are roaring. It's the hottest energy sector of the year. Cameco Corp, Paladin Energy, and BWX Technologies were all up more than 40% in 2024. The biggest market moves could still be ahead of us, and there are seven nuclear energy stocks that could rise much higher in the next several months. To unlock these tickers, enter your email address below.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceHUMAHumacyte0.00%-1.90%-35.42%-42.16%-75.97%IOVAIovance Biotherapeutics0.00%-17.10%-13.23%+27.28%-80.32%ORICOric Pharmaceuticals0.00%+5.03%+2.61%+23.85%+0.59%UPBUpstream Bio0.00%-2.84%+11.89%+87.21%+1,712,999,900.00%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationHUMAHumacyte2.4466 of 5 stars3.52.00.00.02.81.70.6IOVAIovance Biotherapeutics4.6921 of 5 stars4.24.00.04.21.62.51.3ORICOric Pharmaceuticals4.7502 of 5 stars4.53.00.04.42.73.30.6UPBUpstream Bio2.3521 of 5 stars3.50.00.00.03.50.80.6Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceHUMAHumacyte 3.00Buy$9.75529.03% UpsideIOVAIovance Biotherapeutics 2.36Hold$11.90433.63% UpsideORICOric Pharmaceuticals 2.90Moderate Buy$17.6372.29% UpsideUPBUpstream Bio 3.00Buy$56.50229.83% UpsideCurrent Analyst Ratings BreakdownLatest HUMA, ORIC, IOVA, and UPB Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/27/2025HUMAHumacyteBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$3.508/27/2025HUMAHumacyteBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$3.508/19/2025IOVAIovance BiotherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$20.008/14/2025ORICOric PharmaceuticalsJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetOverweight ➝ Overweight$20.00 ➝ $17.008/14/2025ORICOric PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$22.00 ➝ $19.008/13/2025ORICOric PharmaceuticalsGuggenheimSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$18.008/12/2025HUMAHumacyteTD CowenSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$5.00 ➝ $3.508/12/2025HUMAHumacyteHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetBuy ➝ Buy$4.00 ➝ $3.008/12/2025IOVAIovance BiotherapeuticsZacks ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeHold8/12/2025ORICOric PharmaceuticalsZacks ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeHold8/11/2025HUMAHumacyteD. Boral CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$25.00(Data available from 8/31/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookHUMAHumacyte$1.57M156.35N/AN/A($0.41) per share-3.78IOVAIovance Biotherapeutics$164.07M4.92N/AN/A$2.33 per share0.96ORICOric PharmaceuticalsN/AN/AN/AN/A$3.45 per shareN/AUPBUpstream Bio$2.37M389.65N/AN/A$8.77 per share1.95Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateHUMAHumacyte-$148.70M-$0.45N/AN/AN/AN/AN/A-78.26%11/14/2025 (Estimated)IOVAIovance Biotherapeutics-$372.18M-$1.23N/AN/AN/A-161.44%-52.87%-41.31%11/6/2025 (Estimated)ORICOric Pharmaceuticals-$127.85M-$1.89N/AN/AN/AN/A-51.75%-47.09%11/11/2025 (Estimated)UPBUpstream Bio-$62.81MN/A0.00N/AN/A-3,836.58%-35.90%-26.26%11/6/2025 (Estimated)Latest HUMA, ORIC, IOVA, and UPB EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/12/2025Q2 2025ORICOric Pharmaceuticals-$0.46-$0.47-$0.01-$0.47N/AN/A8/11/2025Q2 2025HUMAHumacyte-$0.15-$0.24-$0.09-$0.24$0.94 million$0.30 million8/7/2025Q2 2025IOVAIovance Biotherapeutics-$0.29-$0.33-$0.04-$0.33$67.14 million$59.95 million8/6/2025Q2 2025UPBUpstream Bio-$0.61-$0.74-$0.13-$0.74$0.32 million$0.94 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthHUMAHumacyteN/AN/AN/AN/AN/AIOVAIovance BiotherapeuticsN/AN/AN/AN/AN/AORICOric PharmaceuticalsN/AN/AN/AN/AN/AUPBUpstream BioN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioHUMAHumacyte2.972.451.93IOVAIovance BiotherapeuticsN/A3.272.89ORICOric PharmaceuticalsN/A16.1316.13UPBUpstream BioN/A38.2738.27Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipHUMAHumacyte44.71%IOVAIovance Biotherapeutics77.03%ORICOric Pharmaceuticals95.05%UPBUpstream BioN/AInsider OwnershipCompanyInsider OwnershipHUMAHumacyte5.10%IOVAIovance Biotherapeutics10.30%ORICOric Pharmaceuticals5.55%UPBUpstream Bio13.56%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableHUMAHumacyte150158.37 million150.30 millionOptionableIOVAIovance Biotherapeutics500361.85 million324.58 millionOptionableORICOric Pharmaceuticals8097.12 million91.73 millionOptionableUPBUpstream Bio3853.91 million46.60 millionN/AHUMA, ORIC, IOVA, and UPB HeadlinesRecent News About These CompaniesVelan Capital Investment Management LP Invests $655,000 in Upstream Bio, Inc. $UPBAugust 31 at 7:15 AM | marketbeat.comWellington Management Group LLP Decreases Holdings in Upstream Bio, Inc. $UPBAugust 31 at 3:38 AM | marketbeat.comUpstream Bio (NASDAQ:UPB) Shares Down 5.4% - What's Next?August 27, 2025 | marketbeat.comPiper Sandler bestätigt 'Overweight'-Rating für Upstream Bio und sieht deutliches KurspotenzialAugust 26, 2025 | de.investing.comUpstream Bio (NASDAQ:UPB) Shares Down 4.8% - Here's What HappenedAugust 20, 2025 | marketbeat.comUpstream Bio Initiates Phase 2 Clinical Trial for COPD Drug, VerekitugAugust 20, 2025 | msn.comUpstream Bio (NASDAQ:UPB) Sees Unusually-High Trading Volume - Here's WhyAugust 12, 2025 | marketbeat.comQ3 EPS Estimates for Upstream Bio Cut by William BlairAugust 9, 2025 | marketbeat.comUpstream Bio Second Quarter 2025 Earnings: Revenues Beat Expectations, EPS LagsAugust 8, 2025 | finance.yahoo.comUpstream Bio (UPB) Q2 R&D Soars 169%August 6, 2025 | fool.comUpstream Bio, Inc. reports Q2 resultsAugust 6, 2025 | seekingalpha.comUpstream Bio Reports Second Quarter 2025 Financial Results and Highlights Continued ProgressAugust 6, 2025 | globenewswire.comUpstream Bio (NASDAQ:UPB) Stock Price Up 8.1% - Still a Buy?July 31, 2025 | marketbeat.comPromising Outlook for Upstream Bio, Inc. as Verekitug Advances in Inflammatory ConditionsJuly 28, 2025 | tipranks.comPositive Outlook for Upstream Bio, Inc. Driven by Promising Phase II Study of Verekitug in CRSwNP TreatmentJuly 28, 2025 | tipranks.comUpstream Bio Inc. (UPB) Stock Price Today - WSJJuly 25, 2025 | wsj.comUpstream Bio begins phase 2 COPD trial for verekitugJuly 10, 2025 | uk.investing.comUpstream Bio Announces First Patient Dosed in Phase 2 Clinical Trial of Verekitug in Chronic ...July 8, 2025 | bakersfield.comBUpstream Bio Initiates Phase 2 VENTURE Trial for Verekitug in Moderate-to-Severe COPD, Expanding Its Respiratory PortfolioJuly 8, 2025 | quiverquant.comQUpstream Bio Announces First Patient Dosed in Phase 2 Clinical Trial of Verekitug in Chronic Obstructive Pulmonary Disease (COPD)July 8, 2025 | globenewswire.comUPB Upstream Bio, Inc. - Seeking AlphaJune 28, 2025 | seekingalpha.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesJoby Aviation: Why a Historic Flight Outweighs Analyst DowngradesBy Jeffrey Neal Johnson | August 19, 2025Mercury Systems Up 27%: Financials Send Investors a Clear SignalBy Jeffrey Neal Johnson | August 14, 2025Equal Weight ETFs: Hidden Upside in Today’s MarketBy Gabriel Osorio-Mazilli | August 23, 2025Best Buy Marketplace: Potential Growth Catalyst or Risky Gimmick?By Chris Markoch | August 28, 2025MarketBeat Week in Review – 08/18 - 08/22By MarketBeat Staff | August 23, 2025HUMA, ORIC, IOVA, and UPB Company DescriptionsHumacyte NASDAQ:HUMA$1.55 -0.03 (-1.90%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$1.60 +0.04 (+2.90%) As of 08/29/2025 08:00 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Humacyte, Inc. engages in the development and manufacture of off-the-shelf, implantable, and bioengineered human tissues for the treatment of diseases and conditions across a range of anatomic locations in multiple therapeutic areas. The company using its proprietary and scientific technology platform to engineer and manufacture human acellular vessels (HAVs) to be implanted into patient without inducing a foreign body response or leading to immune rejection. It is developing a portfolio of HAVs, which would target the vascular repair, reconstruction, and replacement market, including vascular trauma; arteriovenous access for hemodialysis; peripheral arterial disease; pediatric heart surgery; and coronary artery bypass grafting, as well as for the delivery of cellular therapy, including pancreatic islet cell transplantation to treat Type 1 diabetes. The company was founded in 2004 and is headquartered in Durham, North Carolina.Iovance Biotherapeutics NASDAQ:IOVA$2.23 0.00 (0.00%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$2.25 +0.02 (+0.90%) As of 08/29/2025 07:57 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Iovance Biotherapeutics, Inc., a commercial-stage biotechnology company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States. The company offers Amtagvi, a tumor-derived autologous T cell immunotherapy used to treat adult patients with unresectable or metastatic melanoma; and Proleukin, an interleukin-2 product for the treatment of patients with metastatic renal cell carcinoma. It also develops lifileucel in combination with pembrolizumab to treat frontline advanced melanoma patients; LN-145 for the treatment of non-small cell lung cancer (NSCLC) and solid tumor cancers; IOV-4001, which is in Phase 1/2 IOV-GM1-201 clinical trial, for the treatment of NSCLC; and lifileucel for gynecological cancers. The company has collaborations and licensing agreements with WuXi Advanced Therapies, Inc.; National Institutes of Health; the National Cancer Institute; H. Lee Moffitt Cancer Center; The University of Texas M.D. Anderson Cancer Center; Cellectis S.A.; Novartis Pharma AG; and Boehringer Ingelheim Biopharmaceuticals GmbH. The company was formerly known as Lion Biotechnologies, Inc. and changed its name to Iovance Biotherapeutics, Inc. in June 2017. Iovance Biotherapeutics, Inc. was incorporated in 2007 and is headquartered in San Carlos, California.Oric Pharmaceuticals NASDAQ:ORIC$10.23 +0.20 (+1.99%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$10.23 0.00 (0.00%) As of 08/29/2025 05:54 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.ORIC Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, engages in the discovery and development of therapies for treatment of cancers in the United States. Its clinical stage product candidates include ORIC-114, a brain penetrant orally bioavailable irreversible inhibitor, currently under Phase 1b study, which is designed to selectively target epidermal growth factor receptor and human epidermal growth factor receptor 2 with high potency towards exon 20 insertion mutations; ORIC-944, an allosteric inhibitor of the polycomb repressive complex 2 for prostate cancer, currently under Phase 1b study; and ORIC-533, an orally bioavailable small molecule inhibitor of CD73, currently under Phase 1b study, being developed for resistance to chemotherapy- and immunotherapy-based treatment regimens. The company is also developing multiple discovery stage precision medicines targeting other cancer resistance mechanisms, including ORIC-613, an orally bioavailable, highly selective inhibitor of PLK4, in preclinical studies for the treatment of breast cancers. It has a license and collaboration agreement with Voronoi Inc.; a license agreement with Mirati Therapeutics, Inc.; and clinical development collaboration agreement with Pfizer Inc. The company was incorporated in 2014 and is headquartered in South San Francisco, California.Upstream Bio NASDAQ:UPB$17.13 +0.37 (+2.21%) Closing price 08/29/2025 04:00 PM EasternExtended Trading$17.80 +0.68 (+3.94%) As of 08/29/2025 04:48 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts. 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