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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
BCRX BioCryst Pharmaceuticals	$8.56 +2.1%	$8.83	$6.01 ▼ $11.31	$1.80B	1.1	3.36 million shs	2.20 million shs
FOLD Amicus Therapeutics	$7.61 +0.1%	$6.35	$5.51 ▼ $12.65	$2.35B	0.53	4.47 million shs	3.92 million shs
ICPT Intercept Pharmaceuticals	$19.00	$18.88	$8.82 ▼ $21.86	$794.77M	0.88	1.36 million shs	N/A
LGND Ligand Pharmaceuticals	$159.08 +1.1%	$131.34	$93.58 ▼ $161.93	$3.12B	0.85	310,662 shs	234,074 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
BCRX BioCryst Pharmaceuticals	+2.15%	+2.27%	-0.58%	-19.17%	+6.87%
FOLD Amicus Therapeutics	+0.13%	+2.84%	+20.60%	+22.35%	-37.06%
ICPT Intercept Pharmaceuticals	0.00%	0.00%	0.00%	0.00%	0.00%
LGND Ligand Pharmaceuticals	+1.13%	+5.30%	+16.79%	+56.57%	+49.96%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	Dividend Strength	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
BCRX BioCryst Pharmaceuticals	4.1969 of 5 stars	3.5	2.0	0.0	4.2	2.5	2.5	0.6
FOLD Amicus Therapeutics	4.3506 of 5 stars	3.4	2.0	0.0	4.3	3.6	0.0	1.9
ICPT Intercept Pharmaceuticals	N/A	N/A	N/A	N/A	N/A	N/A	N/A	N/A
LGND Ligand Pharmaceuticals	4.1252 of 5 stars	1.5	3.0	0.0	4.4	4.1	2.5	1.9

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
BCRX BioCryst Pharmaceuticals	2.90	Moderate Buy	$16.70	95.09% Upside
FOLD Amicus Therapeutics	2.80	Moderate Buy	$16.22	113.17% Upside
ICPT Intercept Pharmaceuticals	0.00	N/A	N/A	N/A
LGND Ligand Pharmaceuticals	3.00	Buy	$157.00	-1.31% Downside

Current Analyst Ratings Breakdown

Latest ICPT, LGND, FOLD, and BCRX Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
8/8/2025	LGND Ligand Pharmaceuticals	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$155.00 ➝ $185.00
8/4/2025	BCRX BioCryst Pharmaceuticals	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$17.00
7/30/2025	LGND Ligand Pharmaceuticals	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$145.00 ➝ $162.00
7/17/2025	FOLD Amicus Therapeutics	Morgan Stanley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Equal Weight ➝ Overweight
7/1/2025	BCRX BioCryst Pharmaceuticals	Bank of America Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$13.00 ➝ $15.00
6/30/2025	BCRX BioCryst Pharmaceuticals	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform ➝ Outperform	$13.00
6/30/2025	BCRX BioCryst Pharmaceuticals	Wedbush Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$16.00 ➝ $18.00
6/25/2025	BCRX BioCryst Pharmaceuticals	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$17.00

(Data available from 8/23/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
BCRX BioCryst Pharmaceuticals	$450.71M	3.99	N/A	N/A	($2.01) per share	-4.26
FOLD Amicus Therapeutics	$528.29M	4.44	N/A	N/A	$0.66 per share	11.53
ICPT Intercept Pharmaceuticals	$285.71M	2.78	N/A	N/A	$1.72 per share	11.05
LGND Ligand Pharmaceuticals	$167.13M	18.66	$1.61 per share	99.00	$42.28 per share	3.76

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
BCRX BioCryst Pharmaceuticals	-$88.88M	-$0.18	N/A	N/A	1.94	-6.41%	N/A	-1.78%	11/3/2025 (Estimated)
FOLD Amicus Therapeutics	-$56.11M	-$0.12	N/A	17.70	N/A	-6.67%	-5.07%	-1.23%	11/5/2025 (Estimated)
ICPT Intercept Pharmaceuticals	$221.82M	-$1.48	N/A	9.84	N/A	-19.39%	-77.48%	-11.99%	N/A
LGND Ligand Pharmaceuticals	-$4.03M	-$4.00	N/A	42.88	N/A	-40.44%	-9.21%	-8.09%	11/6/2025 (Estimated)

Latest ICPT, LGND, FOLD, and BCRX Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue	Details
8/7/2025	Q2 2025	LGND Ligand Pharmaceuticals	$1.54	$1.60	+$0.06	$0.24	$43.87 million	$47.63 million
8/4/2025	Q2 2025	BCRX BioCryst Pharmaceuticals	$0.03	$0.15	+$0.12	$0.02	$149.59 million	$163.35 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
BCRX BioCryst Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
FOLD Amicus Therapeutics	N/A	N/A	N/A	N/A	N/A
ICPT Intercept Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
LGND Ligand Pharmaceuticals	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
BCRX BioCryst Pharmaceuticals	N/A	2.25	2.22
FOLD Amicus Therapeutics	1.92	3.21	2.29
ICPT Intercept Pharmaceuticals	3.12	4.22	2.52
LGND Ligand Pharmaceuticals	N/A	5.45	5.21

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
BCRX BioCryst Pharmaceuticals	85.88%
FOLD Amicus Therapeutics	N/A
ICPT Intercept Pharmaceuticals	83.81%
LGND Ligand Pharmaceuticals	91.28%

Insider Ownership

Company	Insider Ownership
BCRX BioCryst Pharmaceuticals	5.10%
FOLD Amicus Therapeutics	2.20%
ICPT Intercept Pharmaceuticals	6.20%
LGND Ligand Pharmaceuticals	7.00%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
BCRX BioCryst Pharmaceuticals	530	209.92 million	199.21 million	Optionable
FOLD Amicus Therapeutics	480	308.24 million	301.46 million	Optionable
ICPT Intercept Pharmaceuticals	341	41.83 million	39.19 million	Optionable
LGND Ligand Pharmaceuticals	80	19.60 million	18.23 million	Optionable

ICPT, LGND, FOLD, and BCRX Headlines

Recent News About These Companies

Invesco Ltd. Purchases 8,473 Shares of Ligand Pharmaceuticals Incorporated $LGND

August 23 at 4:16 AM | marketbeat.com

A Fresh Look at Ligand Pharmaceuticals (LGND) Valuation Following $400 Million Convertible Note Offering and Capital Structure Shift

August 22 at 10:33 AM | finance.yahoo.com

Connor Clark & Lunn Investment Management Ltd. Reduces Position in Ligand Pharmaceuticals Incorporated $LGND

August 22 at 3:38 AM | marketbeat.com

Ligand Pharmaceuticals Incorporated $LGND Shares Sold by Vanguard Group Inc.

August 22 at 3:18 AM | marketbeat.com

Ligand Pharmaceuticals Incorporated $LGND Shares Bought by Aberdeen Group plc

August 20 at 5:20 AM | marketbeat.com

Ligand Pharmaceuticals Inc (LGND) Announces Participation in Upcoming Investor Conferences | ...

August 19, 2025 | gurufocus.com

Ligand Pharmaceuticals to Participate in Upcoming Investor Conferences in September 2025

August 19, 2025 | quiverquant.comQ

Ligand to Participate in September Investor Conferences

August 19, 2025 | globenewswire.com

Russell Investments Group Ltd. Has $14.23 Million Stake in Ligand Pharmaceuticals Incorporated $LGND

August 19, 2025 | marketbeat.com

Public Sector Pension Investment Board Grows Stock Holdings in Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

August 18, 2025 | marketbeat.com

Ligand Pharma Completes $460M Convertible Notes Offering

August 14, 2025 | msn.com

Ligand Announces Closing of Convertible Senior Notes Offering

August 14, 2025 | globenewswire.com

US Bancorp DE Purchases 3,301 Shares of Ligand Pharmaceuticals Incorporated (NASDAQ:LGND)

August 14, 2025 | marketbeat.com

Ligand Pharmaceuticals (NASDAQ:LGND) Sets New 52-Week High - Should You Buy?

August 13, 2025 | marketbeat.com

Ligand Pharmaceuticals (NASDAQ:LGND) Shares Gap Down - Should You Sell?

August 12, 2025 | marketbeat.com

Ligand Pharmaceuticals Incorporated (NASDAQ:LGND) Shares Purchased by Townsquare Capital LLC

August 12, 2025 | marketbeat.com

Analysts Are Bullish on Top Healthcare Stocks: Insmed (INSM), Ligand Pharma (LGND)

August 12, 2025 | theglobeandmail.com

Ligand Pharmaceuticals to offer $400M convertible senior notes in private placement

August 12, 2025 | msn.com

LGND: Getting In Tune with MedTech

August 12, 2025 | msn.com

Ligand prices $400M convertible debt offering

August 12, 2025 | msn.com

Ligand Pharmaceuticals Inc (LGND) Announces Pricing of $400 Million Convertible Senior Notes | ...

August 12, 2025 | gurufocus.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

ICPT, LGND, FOLD, and BCRX Company Descriptions

BioCryst Pharmaceuticals NASDAQ:BCRX

$8.56 +0.18 (+2.15%)

Closing price 08/22/2025 04:00 PM Eastern

Extended Trading

$8.51 -0.05 (-0.63%)

As of 08/22/2025 07:57 PM Eastern

BioCryst Pharmaceuticals, Inc., a biotechnology company, develops oral small-molecule and protein therapeutics to treat rare diseases. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX10013, an oral factor D inhibitor for complement-mediated diseases. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd.; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

Amicus Therapeutics NASDAQ:FOLD

$7.61 +0.01 (+0.13%)

Closing price 08/22/2025 04:00 PM Eastern

Extended Trading

$7.62 +0.01 (+0.13%)

As of 08/22/2025 07:41 PM Eastern

Amicus Therapeutics, Inc., a biotechnology company, focuses on discovering, developing, and delivering medicines for rare diseases. Its commercial product and product candidates include Galafold, an oral precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant; and Pombiliti + Opfolda, for the treatment of late onset. It has collaboration and license agreements with the University of Pennsylvania to research and develop parvovirus gene therapy products; and GlaxoSmithKline. Amicus Therapeutics, Inc. was incorporated in 2002 and is headquartered in Princeton, New Jersey.

Intercept Pharmaceuticals NASDAQ:ICPT

Intercept Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the development and commercialization of therapeutics to treat progressive non-viral liver diseases in the United States, Europe, and Canada. The company markets Ocaliva, a farnesoid X receptor agonist used for the treatment of primary biliary cholangitis in combination with ursodeoxycholic acid in adults. It is also developing Ocaliva for various indications, including nonalcoholic steatohepatitis and NASH; and other product candidates in various stages of clinical and preclinical development. The company has a license agreement with Aralez Pharmaceuticals Canada Inc. to develop and commercialize bezafibrate in the United States. It markets its products through an internal commercial organization and third-party distributors. The company was incorporated in 2002 and is headquartered in Morristown, New Jersey. As of November 8, 2023, Intercept Pharmaceuticals, Inc. operates as a subsidiary of Alfasigma S.p.A..

Ligand Pharmaceuticals NASDAQ:LGND

$159.08 +1.77 (+1.13%)

Closing price 08/22/2025 04:00 PM Eastern

Extended Trading

$159.07 -0.01 (-0.01%)

As of 08/22/2025 04:35 PM Eastern

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and Evomela, which are used to treat multiple myeloma; Rylaze, a recombinant erwinia asparaginase for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; Filspari, a dual endothelin and angiotensin II receptor antagonist in development for rare kidney diseases and non-immunosuppressive treatment indicated for immunoglobulin A nephropathy; Teriparatide injection product for osteoporosis; Vaxneuvance for the prevention of invasive disease caused by streptococcus pneumoniae serotypes; and Pneumosil, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia among children. The company also offers TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes (T1D) in adults and children aged 8 years and older with Stage 2 T1D; Nexterone, a captisol-enabled formulation of amiodarone; Zulresso, a captisol-enabled formulation of brexanolone for the treatment of postpartum depression; and Veklury, an antiviral treatment for moderate or severe COVID-19. In addition, it provides Noxafil-IV, a captisol-enabled formulation of posaconazole for IV use; Duavee for the treatment of post-menopausal symptoms in women; Exemptia for autoimmune diseases; Vivitra for breast cancer; and Bryxta and Zybev for various indications. The company has alliances, licenses, and other business relationships with Amgen, Merck, Pfizer, Jazz, Takeda, Gilead Sciences, and Baxter International. Further, it sells Captisol materials. Ligand Pharmaceuticals Incorporated was incorporated in 1987 and is based in Jupiter, Florida.

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Comparative Price Performance Over Time