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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
BCRX BioCryst Pharmaceuticals	$8.31 -1.9%	$8.67	$6.01 ▼ $11.31	$1.74B	1.1	2.97 million shs	2.31 million shs
FOLD Amicus Therapeutics	$7.59 -0.8%	$6.53	$5.51 ▼ $12.65	$2.34B	0.53	4.06 million shs	4.15 million shs
LGND Ligand Pharmaceuticals	$161.71 +1.1%	$135.91	$93.58 ▼ $163.34	$3.17B	0.85	310,350 shs	147,031 shs
MNKD MannKind	$4.59 +2.2%	$3.85	$3.38 ▼ $7.63	$1.41B	1.02	3.82 million shs	4.21 million shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
BCRX BioCryst Pharmaceuticals	0.00%	-2.92%	+2.09%	-22.55%	-2.81%
FOLD Amicus Therapeutics	0.00%	-0.26%	+26.71%	+24.22%	-32.29%
LGND Ligand Pharmaceuticals	0.00%	+1.65%	+22.90%	+56.74%	+51.78%
MNKD MannKind	0.00%	+11.68%	+21.43%	+10.34%	-22.20%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
BCRX BioCryst Pharmaceuticals	4.1084 of 5 stars	3.5	2.0	4.2	2.6	2.5	0.6
FOLD Amicus Therapeutics	4.121 of 5 stars	3.4	2.0	4.3	2.7	0.0	1.9
LGND Ligand Pharmaceuticals	3.8225 of 5 stars	1.5	3.0	4.4	2.9	2.5	1.9
MNKD MannKind	3.8986 of 5 stars	3.6	2.0	0.0	3.2	1.7	3.1

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
BCRX BioCryst Pharmaceuticals	2.90	Moderate Buy	$16.70	100.96% Upside
FOLD Amicus Therapeutics	2.80	Moderate Buy	$16.22	113.73% Upside
LGND Ligand Pharmaceuticals	3.00	Buy	$165.17	2.14% Upside
MNKD MannKind	3.29	Buy	$9.50	106.97% Upside

Current Analyst Ratings Breakdown

Latest MNKD, LGND, FOLD, and BCRX Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
8/28/2025	LGND Ligand Pharmaceuticals	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$157.00 ➝ $206.00
8/26/2025	MNKD MannKind	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$7.00 ➝ $8.00
8/25/2025	MNKD MannKind	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$9.00
8/8/2025	LGND Ligand Pharmaceuticals	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$155.00 ➝ $185.00
8/7/2025	MNKD MannKind	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Outperform ➝ Outperform	$8.00 ➝ $7.00
8/4/2025	BCRX BioCryst Pharmaceuticals	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$17.00
7/30/2025	LGND Ligand Pharmaceuticals	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$145.00 ➝ $162.00
7/23/2025	MNKD MannKind	Royal Bank Of Canada Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Outperform ➝ Outperform	$10.00 ➝ $8.00
7/17/2025	FOLD Amicus Therapeutics	Morgan Stanley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Equal Weight ➝ Overweight
7/16/2025	MNKD MannKind	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Buy	$9.00
7/1/2025	BCRX BioCryst Pharmaceuticals	Bank of America Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$13.00 ➝ $15.00

(Data available from 8/31/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
BCRX BioCryst Pharmaceuticals	$557.51M	3.13	N/A	N/A	($2.01) per share	-4.13
FOLD Amicus Therapeutics	$528.29M	4.43	N/A	N/A	$0.66 per share	11.50
LGND Ligand Pharmaceuticals	$167.13M	18.96	$1.61 per share	100.64	$42.28 per share	3.82
MNKD MannKind	$301.74M	4.67	$0.14 per share	33.07	($0.18) per share	-25.50

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
BCRX BioCryst Pharmaceuticals	-$88.88M	-$0.18	N/A	N/A	1.89	-6.41%	N/A	-1.78%	11/3/2025 (Estimated)
FOLD Amicus Therapeutics	-$56.11M	-$0.12	N/A	17.65	N/A	-6.67%	-5.07%	-1.23%	11/5/2025 (Estimated)
LGND Ligand Pharmaceuticals	-$4.03M	-$4.00	N/A	43.59	N/A	-40.44%	-9.21%	-8.09%	11/6/2025 (Estimated)
MNKD MannKind	$27.59M	$0.11	41.73	19.96	N/A	10.87%	-32.60%	7.81%	11/6/2025 (Estimated)

Latest MNKD, LGND, FOLD, and BCRX Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/7/2025	Q2 2025	LGND Ligand Pharmaceuticals	$1.54	$1.60	+$0.06	$0.24	$43.87 million	$47.63 million
8/6/2025	Q2 2025	MNKD MannKind	$0.04	$0.05	+$0.01	N/A	$77.82 million	$76.53 million
8/4/2025	Q2 2025	BCRX BioCryst Pharmaceuticals	$0.03	$0.15	+$0.12	$0.02	$149.59 million	$163.35 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
BCRX BioCryst Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
FOLD Amicus Therapeutics	N/A	N/A	N/A	N/A	N/A
LGND Ligand Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
MNKD MannKind	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
BCRX BioCryst Pharmaceuticals	N/A	2.25	2.22
FOLD Amicus Therapeutics	1.92	3.21	2.29
LGND Ligand Pharmaceuticals	N/A	5.45	5.21
MNKD MannKind	N/A	2.50	2.24

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
BCRX BioCryst Pharmaceuticals	85.88%
FOLD Amicus Therapeutics	N/A
LGND Ligand Pharmaceuticals	91.28%
MNKD MannKind	49.55%

Insider Ownership

Company	Insider Ownership
BCRX BioCryst Pharmaceuticals	5.10%
FOLD Amicus Therapeutics	2.20%
LGND Ligand Pharmaceuticals	7.00%
MNKD MannKind	2.70%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
BCRX BioCryst Pharmaceuticals	530	209.92 million	199.21 million	Optionable
FOLD Amicus Therapeutics	480	308.24 million	301.46 million	Optionable
LGND Ligand Pharmaceuticals	80	19.60 million	18.23 million	Optionable
MNKD MannKind	400	306.83 million	298.54 million	Optionable

MNKD, LGND, FOLD, and BCRX Headlines

Recent News About These Companies

MannKind (NASDAQ:MNKD) Stock Price Up 10.4% on Analyst Upgrade

August 29 at 10:45 AM | marketbeat.com

Invesco Ltd. Grows Position in MannKind Corporation $MNKD

August 29 at 3:23 AM | marketbeat.com

MannKind (NASDAQ:MNKD) Shares Up 10.4% Following Analyst Upgrade

August 29 at 2:13 AM | americanbankingnews.com

MannKind to Present at Upcoming Investor Conferences

August 27, 2025 | globenewswire.com

MannKind (NASDAQ:MNKD) Stock Price Down 5.2% - Here's What Happened

August 27, 2025 | marketbeat.com

MannKind Announces Expansion of United Therapeutics Collaboration for Second Inhaled Therapy

August 27, 2025 | markets.businessinsider.com

MannKind Corporation Collaborates with United Therapeutics to Develop Second Dry Powder Inhalation Therapy

August 27, 2025 | quiverquant.comQ

MannKind Announces Expansion of United Therapeutics Collaboration for Second Inhaled Therapy

August 27, 2025 | globenewswire.com

New Strong Sell Stocks for August 27th

August 27, 2025 | zacks.com

MannKind (NASDAQ:MNKD) Price Target Raised to $8.00

August 27, 2025 | americanbankingnews.com

SCPHARMACEUTICALS INVESTOR ALERT by the Former Attorney General of Louisiana: Kahn Swick & Foti, LLC Investigates Adequacy of Price and Process in Proposed Sale of scPharmaceuticals Inc. - SCPH

August 26, 2025 | businesswire.com

Vanguard Group Inc. Acquires 1,263,622 Shares of MannKind Corporation $MNKD

August 26, 2025 | marketbeat.com

MannKind Corporation (MNKD) Mergers and Acquisition Call Transcript

August 25, 2025 | seekingalpha.com

MannKind, Backed By Blackstone, Expands Cardiorenal Focus With $360 Million Deal

August 25, 2025 | benzinga.com

MannKind’s Strategic Acquisition of scPharmaceuticals: A Catalyst for Future Growth and Value Creation

August 25, 2025 | tipranks.com

MannKind (MNKD) to Acquire scPharmaceuticals for $360 Million

August 25, 2025 | gurufocus.com

MannKind’s Strategic Acquisition and Growth Prospects: A Buy Rating by Yun Zhong

August 25, 2025 | tipranks.com

SCPH Stock Alert: Halper Sadeh LLC Is Investigating Whether the Sale of scPharmaceuticals Inc. Is Fair to Shareholders

August 25, 2025 | mms.businesswire.com

MannKind to buy scPharmaceuticals to expand its cardiometabolic business

August 25, 2025 | seekingalpha.com

MannKind to Buy ScPharmaceuticals for Up to $360 Million

August 25, 2025 | marketwatch.com

Shareholder Alert: The Ademi Firm Investigates Whether scPharmaceuticals Inc. Is Obtaining a Fair Price for Its Public Shareholders

August 25, 2025 | mms.businesswire.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

MNKD, LGND, FOLD, and BCRX Company Descriptions

BioCryst Pharmaceuticals NASDAQ:BCRX

$8.31 -0.16 (-1.89%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$8.35 +0.04 (+0.42%)

As of 08/29/2025 07:05 PM Eastern

BioCryst Pharmaceuticals, Inc., a biotechnology company, develops oral small-molecule and protein therapeutics to treat rare diseases. The company markets peramivir injection, an intravenous neuraminidase inhibitor for the treatment of acute uncomplicated influenza under the RAPIVAB, RAPIACTA, and PERAMIFLU names; and ORLADEYO, an oral serine protease inhibitor to treat hereditary angioedema. It is also developing BCX10013, an oral factor D inhibitor for complement-mediated diseases. The company has collaborations and in-license relationships with the Torii Pharmaceutical Co., Ltd.; Seqirus UK Limited; Shionogi & Co., Ltd.; Green Cross Corporation; National Institute of Allergy and Infectious Diseases; Biomedical Advanced Research and Development Authority; the U.S. Department of Health and Human Services; and The University of Alabama at Birmingham, as well as Albert Einstein College of Medicine of Yeshiva University and Industrial Research, Ltd. BioCryst Pharmaceuticals, Inc. was founded in 1986 and is headquartered in Durham, North Carolina.

Amicus Therapeutics NASDAQ:FOLD

$7.59 -0.06 (-0.78%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$7.58 0.00 (-0.07%)

As of 08/29/2025 05:38 PM Eastern

Amicus Therapeutics, Inc., a biotechnology company, focuses on discovering, developing, and delivering medicines for rare diseases. Its commercial product and product candidates include Galafold, an oral precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant; and Pombiliti + Opfolda, for the treatment of late onset. It has collaboration and license agreements with the University of Pennsylvania to research and develop parvovirus gene therapy products; and GlaxoSmithKline. Amicus Therapeutics, Inc. was incorporated in 2002 and is headquartered in Princeton, New Jersey.

Ligand Pharmaceuticals NASDAQ:LGND

$161.71 +1.75 (+1.09%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$161.83 +0.12 (+0.07%)

As of 08/29/2025 04:39 PM Eastern

Ligand Pharmaceuticals Incorporated, a biopharmaceutical company, engages in the development and licensing of biopharmaceutical assets worldwide. Its commercial programs include Kyprolis and Evomela, which are used to treat multiple myeloma; Rylaze, a recombinant erwinia asparaginase for the treatment of acute lymphoblastic leukemia or lymphoblastic lymphoma in adult and pediatric patients; Filspari, a dual endothelin and angiotensin II receptor antagonist in development for rare kidney diseases and non-immunosuppressive treatment indicated for immunoglobulin A nephropathy; Teriparatide injection product for osteoporosis; Vaxneuvance for the prevention of invasive disease caused by streptococcus pneumoniae serotypes; and Pneumosil, a pneumococcal conjugate vaccine to help fight against pneumococcal pneumonia among children. The company also offers TZIELD, a CD3-directed antibody indicated to delay the onset of Stage 3 type 1 diabetes (T1D) in adults and children aged 8 years and older with Stage 2 T1D; Nexterone, a captisol-enabled formulation of amiodarone; Zulresso, a captisol-enabled formulation of brexanolone for the treatment of postpartum depression; and Veklury, an antiviral treatment for moderate or severe COVID-19. In addition, it provides Noxafil-IV, a captisol-enabled formulation of posaconazole for IV use; Duavee for the treatment of post-menopausal symptoms in women; Exemptia for autoimmune diseases; Vivitra for breast cancer; and Bryxta and Zybev for various indications. The company has alliances, licenses, and other business relationships with Amgen, Merck, Pfizer, Jazz, Takeda, Gilead Sciences, and Baxter International. Further, it sells Captisol materials. Ligand Pharmaceuticals Incorporated was incorporated in 1987 and is based in Jupiter, Florida.

MannKind NASDAQ:MNKD

$4.59 +0.10 (+2.23%)

Closing price 08/29/2025 04:00 PM Eastern

Extended Trading

$4.61 +0.02 (+0.44%)

As of 08/29/2025 07:52 PM Eastern

MannKind Corporation, a biopharmaceutical company, focuses on the development and commercialization of inhaled therapeutic products for endocrine and orphan lung diseases in the United States. It offers Afrezza, an inhaled insulin used to improve glycemic control in adults with diabetes, and the V-Go wearable insulin delivery device, which provides continuous subcutaneous infusion of insulin in adults. The company's product pipeline also includes Tyvaso DPI (Treprostinil), an inhalation powder for the treatment of pulmonary arterial hypertension and pulmonary hypertension associated with interstitial lung disease; MNKD-101, a nebulized formulation of clofazimine, for the treatment of severe chronic and recurrent pulmonary infections, including nontuberculous mycobacterial lung disease; MNKD-201, a dry-powder formulation of nintedanib, for the treatment of idiopathic pulmonary fibrosis (IPF). In addition, it has collaboration and license agreement with United Therapeutics Corporation for development, regulatory, and commercial activities of Tyvaso DPI; co-promotion agreement with Vertice Pharma to promote Thyquidity; and collaboration agreement with Thirona to evaluate the therapeutic for the treatment of pulmonary fibrosis. Further, the company has supply and distribution agreement with Biomm S.A. for the commercialization of Afrezza in Brazil; and license and distribution agreement with Cipla Ltd. for the marketing and distribution of Afrezza in India. MannKind Corporation was incorporated in 1991 and is headquartered in Danbury, Connecticut.

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Comparative Price Performance Over Time