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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:CRNXNASDAQ:PHVSNASDAQ:PTGXNASDAQ:SRRK On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCRNXCrinetics Pharmaceuticals$34.73-0.5%$36.02$31.84▼$62.53$3.23B0.58830,038 shs690,164 shsPHVSPharvaris$15.80+1.5%$16.73$14.14▼$25.50$826.18M-3.0272,293 shs35,808 shsPTGXProtagonist Therapeutics$48.88-1.1%$42.54$24.22▼$60.60$3.00B2.34796,889 shs664,503 shsSRRKScholar Rock$32.84-1.6%$37.74$6.76▼$46.98$3.11B0.591.17 million shs1.13 million shsThese 7 Stocks Will Be Magnificent in 2025Discover the next wave of investment opportunities with our report, 7 Stocks That Will Be Magnificent in 2025. Explore companies poised to replicate the growth, innovation, and value creation of the tech giants dominating today's markets.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCRNXCrinetics Pharmaceuticals0.00%+0.90%+4.58%-33.02%-21.83%PHVSPharvaris0.00%+2.60%+1.54%-18.68%-32.77%PTGXProtagonist Therapeutics0.00%-7.16%+34.51%+25.46%+71.63%SRRKScholar Rock0.00%-0.64%-8.68%-26.14%+112.56%Remove AdsCompare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationCRNXCrinetics Pharmaceuticals4.3746 of 5 stars4.52.00.03.73.32.50.0PHVSPharvaris1.5352 of 5 stars3.51.00.00.02.70.80.0PTGXProtagonist Therapeutics3.5975 of 5 stars4.51.00.00.03.42.51.3SRRKScholar Rock3.9922 of 5 stars3.50.00.04.42.73.30.6Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceCRNXCrinetics Pharmaceuticals 2.92Moderate Buy$73.00110.19% UpsidePHVSPharvaris 3.00Buy$40.50156.33% UpsidePTGXProtagonist Therapeutics 3.00Buy$62.5627.98% UpsideSRRKScholar Rock 3.00Buy$42.6729.92% UpsideCurrent Analyst Ratings BreakdownLatest PHVS, PTGX, CRNX, and SRRK Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails3/28/2025PTGXProtagonist TherapeuticsWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform$70.00 ➝ $70.003/25/2025CRNXCrinetics PharmaceuticalsStifel NicolausSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageBuy$60.003/25/2025SRRKScholar RockWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform$50.003/17/2025SRRKScholar RockWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform$50.003/11/2025PTGXProtagonist TherapeuticsWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform$70.003/11/2025PTGXProtagonist TherapeuticsTruist FinancialSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$60.00 ➝ $76.003/11/2025PTGXProtagonist TherapeuticsBMO Capital MarketsSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$62.00 ➝ $72.003/10/2025PTGXProtagonist TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$54.00 ➝ $54.003/4/2025PTGXProtagonist TherapeuticsJPMorgan Chase & Co.Subscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOverweight ➝ Overweight$53.00 ➝ $57.003/3/2025PTGXProtagonist TherapeuticsBTIG ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingSet Price Target$73.003/3/2025PTGXProtagonist TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$54.00 ➝ $54.00(Data available from 3/30/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookCRNXCrinetics Pharmaceuticals$1.04M3,110.29N/AN/A$8.07 per share4.30PHVSPharvarisN/AN/AN/AN/A$7.95 per shareN/APTGXProtagonist Therapeutics$434.43M6.91N/AN/A$5.84 per share8.37SRRKScholar Rock$33.19M93.68N/AN/A$3.12 per share10.53Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateCRNXCrinetics Pharmaceuticals-$214.53M-$3.71N/AN/AN/AN/A-36.12%-31.89%5/8/2025 (Estimated)PHVSPharvaris-$109.18M-$2.80N/AN/AN/AN/A-38.52%-36.69%4/9/2025 (Estimated)PTGXProtagonist Therapeutics-$78.96M$4.2018.38N/AN/A52.76%34.68%30.98%5/6/2025 (Estimated)SRRKScholar Rock-$165.79M-$2.45N/AN/AN/AN/A-145.60%-91.83%5/6/2025 (Estimated)Latest PHVS, PTGX, CRNX, and SRRK EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails4/9/2025N/APHVSPharvaris-$0.74N/AN/AN/AN/AN/A2/27/2025Q4 2024CRNXCrinetics Pharmaceuticals-$0.92-$0.88+$0.04-$0.88$0.73 millionN/A2/21/2025Q4 2024PTGXProtagonist Therapeutics-$0.09$1.98+$2.07$1.98$56.65 million$170.64 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthCRNXCrinetics PharmaceuticalsN/AN/AN/AN/AN/APHVSPharvarisN/AN/AN/AN/AN/APTGXProtagonist TherapeuticsN/AN/AN/AN/AN/ASRRKScholar RockN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioCRNXCrinetics PharmaceuticalsN/A16.3916.38PHVSPharvarisN/A19.0819.08PTGXProtagonist TherapeuticsN/A10.6910.70SRRKScholar Rock0.633.883.88Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipCRNXCrinetics Pharmaceuticals98.51%PHVSPharvarisN/APTGXProtagonist Therapeutics98.63%SRRKScholar Rock91.08%Insider OwnershipCompanyInsider OwnershipCRNXCrinetics Pharmaceuticals6.00%PHVSPharvaris11.84%PTGXProtagonist Therapeutics5.40%SRRKScholar Rock19.20%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableCRNXCrinetics Pharmaceuticals21093.05 million87.17 millionOptionablePHVSPharvaris3052.29 million46.10 millionNot OptionablePTGXProtagonist Therapeutics12061.38 million56.38 millionOptionableSRRKScholar Rock14094.68 million75.64 millionOptionablePHVS, PTGX, CRNX, and SRRK HeadlinesRecent News About These CompaniesAmerican Century Companies Inc. Acquires New Holdings in Scholar Rock Holding Co. (NASDAQ:SRRK)March 30 at 3:45 AM | marketbeat.comRaymond James Financial Inc. Takes Position in Scholar Rock Holding Co. (NASDAQ:SRRK)March 30 at 3:15 AM | marketbeat.comLoomis Sayles & Co. L P Makes New Investment in Scholar Rock Holding Co. (NASDAQ:SRRK)March 29 at 5:47 AM | marketbeat.comBIT Capital GmbH Decreases Position in Scholar Rock Holding Co. (NASDAQ:SRRK)March 28 at 6:31 AM | marketbeat.comScholar Rock Announces FDA Priority Review Designation For Apitegromab - Quick FactsMarch 27 at 11:33 AM | nasdaq.comFDA accepts Scholar Rock BLA for apitegromab under priority review to treat SMAMarch 27 at 11:33 AM | markets.businessinsider.comInsider Selling: Scholar Rock Holding Co. (NASDAQ:SRRK) Insider Sells 6,500 Shares of StockMarch 26, 2025 | marketbeat.comScholar Rock (NASDAQ:SRRK) Receives "Outperform" Rating from WedbushMarch 26, 2025 | marketbeat.comSwiss National Bank Boosts Stock Position in Scholar Rock Holding Co. (NASDAQ:SRRK)March 25, 2025 | marketbeat.comVictory Capital Management Inc. Takes Position in Scholar Rock Holding Co. (NASDAQ:SRRK)March 23, 2025 | marketbeat.comAlphaQuest LLC Sells 34,414 Shares of Scholar Rock Holding Co. (NASDAQ:SRRK)March 21, 2025 | marketbeat.comScholar Rock Holding Co. (NASDAQ:SRRK) Director Katie Peng Sells 1,006 SharesMarch 20, 2025 | marketbeat.com54,717 Shares in Scholar Rock Holding Co. (NASDAQ:SRRK) Bought by Proficio Capital Partners LLCMarch 19, 2025 | marketbeat.comWedbush Reaffirms "Outperform" Rating for Scholar Rock (NASDAQ:SRRK)March 18, 2025 | marketbeat.comSkandinaviska Enskilda Banken AB publ Buys Shares of 28,599 Scholar Rock Holding Co. (NASDAQ:SRRK)March 18, 2025 | marketbeat.comCharles Schwab Investment Management Inc. Purchases 119,616 Shares of Scholar Rock Holding Co. (NASDAQ:SRRK)March 18, 2025 | marketbeat.comTD Cowen Reaffirms Their Buy Rating on Scholar Rock Holding (SRRK)March 17, 2025 | markets.businessinsider.comScholar Rock announces Phase 3 SAPPHIRE dataMarch 16, 2025 | markets.businessinsider.comScholar Rock Presents New Phase 3 SAPPHIRE Data at the 2025 Muscular Dystrophy Association Clinical & Scientific ConferenceMarch 16, 2025 | businesswire.comScholar Rock issues equity awards to new employeesMarch 16, 2025 | investing.comBank of New York Mellon Corp Has $8.97 Million Position in Scholar Rock Holding Co. (NASDAQ:SRRK)March 15, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over TimePHVS, PTGX, CRNX, and SRRK Company DescriptionsCrinetics Pharmaceuticals NASDAQ:CRNX$34.73 -0.17 (-0.49%) Closing price 03/28/2025 04:00 PM EasternExtended Trading$35.46 +0.73 (+2.09%) As of 03/28/2025 05:55 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Crinetics Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. The company's lead product candidate is paltusotine, an oral selective nonpeptide somatostatin receptor type 2 agonist, which is in Phase 3 trial for the treatment of acromegaly; and Phase 2 trial for treating carcinoid syndrome associated with neuroendocrine tumors. It is also developing CRN04894, an investigational oral nonpeptide product candidate to antagonize the adrenocorticotrophic hormone (ACTH) receptor that has completed a Phase 1 study for the treatment of diseases caused by excess ACTH, including congenital adrenal hyperplasia and Cushing's disease. In addition, the company is developing antagonists of the parathyroid hormone (PTH) receptor for the treatment of primary hyperparathyroidism and humoral hypercalcemia of malignancy, and other diseases of excess PTH; identified investigational orally available somatostatin receptor type 3 targeted nonpeptide agonists for the treatment of autosomal dominant polycystic kidney disease; and developing thyroid-stimulating hormone receptor antagonists for the treatment of graves' disease and thyroid eye disease, as well as Oral GLP-1 and GIP nonpeptides for the treatment of diabetes and obesity. Crinetics Pharmaceuticals, Inc. was incorporated in 2008 and is headquartered in San Diego, California.Pharvaris NASDAQ:PHVS$15.80 +0.23 (+1.48%) Closing price 03/28/2025 04:00 PM EasternExtended Trading$15.80 +0.00 (+0.03%) As of 03/28/2025 04:05 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Pharvaris N.V., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapies for rare diseases. The company develops PHA121, a small molecule bradykinin B2-receptor antagonist for the treatment of hereditary angioedema (HAE). It also develops PHVS416, an on-demand, rapid exposure soft capsule for patients suffering from acute HAE attacks which is under Phase 2 clinical trial; and PHVS719, a prophylactic extended-release tablet for HAE patients which is under Phase 1 clinical trial. The company operates in the Netherlands, Switzerland, and the United States. Pharvaris N.V. was incorporated in 2015 and is based in Leiden, the Netherlands.Protagonist Therapeutics NASDAQ:PTGX$48.88 -0.56 (-1.13%) Closing price 03/28/2025 04:00 PM EasternExtended Trading$48.88 0.00 (0.00%) As of 03/28/2025 04:34 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide-based drugs for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide (PTG-300), an injectable hepcidin mimetic that completed phase 2 clinical trials for the treatment of polycythemia vera and other blood disorders; and JNJ-2113, an orally delivered investigational drug to block biological pathways that completed phase 2b clinical trials for the treatment of moderate-to-severe plaque psoriasis; and PN-943, an orally delivered, gut-restricted alpha 4 beta 7 specific integrin antagonist completed a phase 2 clinical trials in patients with moderate to severe ulcerative colitis. The company has a license and collaboration agreement with Takeda to commercialize rusfertide; and JNJ Innovative Medicines to co-develop Interleukin-23 receptor antagonist compound JNJ-2113. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.Scholar Rock NASDAQ:SRRK$32.84 -0.52 (-1.56%) Closing price 03/28/2025 04:00 PM EasternExtended Trading$32.85 +0.01 (+0.05%) As of 03/28/2025 04:05 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Scholar Rock Holding Corporation, a biopharmaceutical company, focuses on the discovery, development, and delivery of medicines for the treatment of serious diseases in which signaling by protein growth factors plays a fundamental role. The company develops Apitegromab, an inhibitor of the activation of myostatin that is in Phase 3 clinical trial for the treatment of spinal muscular atrophy; and SRK-181, which has completed Phase 1 clinical trials for the treatment of cancers that are resistant to checkpoint inhibitor therapies, such as anti-PD-1 or anti-PD-L1 antibody therapies. It is developing a pipeline of product candidates to deliver novel therapies to treat a range of serious diseases, including neuromuscular disorders, cardiometabolic disorders, cancer, fibrosis, and iron-restricted anemia. Scholar Rock Holding Corporation was founded in 2012 and is headquartered in Cambridge, Massachusetts. 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