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Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
INSP Inspire Medical Systems	$126.94 -0.8%	$136.24	$123.00 ▼ $225.00	$3.74B	1.25	557,968 shs	406,188 shs
PLSE Pulse Biosciences	$15.10 -3.5%	$16.20	$13.50 ▼ $25.00	$1.02B	1.56	173,968 shs	210,216 shs
SLNO Soleno Therapeutics	$87.20 -0.5%	$79.81	$41.50 ▼ $90.32	$4.39B	-2.63	856,334 shs	1.19 million shs
TMDX TransMedics Group	$109.88 -2.3%	$127.13	$55.00 ▼ $177.37	$3.72B	2.06	1.38 million shs	789,501 shs

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
INSP Inspire Medical Systems	0.00%	-2.71%	-2.93%	-12.30%	-11.69%
PLSE Pulse Biosciences	0.00%	-5.80%	-1.31%	-12.67%	-5.39%
SLNO Soleno Therapeutics	0.00%	+6.90%	+9.03%	+26.51%	+85.69%
TMDX TransMedics Group	0.00%	-2.29%	-11.07%	+25.26%	-25.35%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	ESG Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
INSP Inspire Medical Systems	4.546 of 5 stars	3.4	2.0	4.8	2.3	2.5	1.9
PLSE Pulse Biosciences	2.7907 of 5 stars	3.5	0.0	4.2	0.0	4.2	0.0
SLNO Soleno Therapeutics	4.2864 of 5 stars	3.5	1.0	4.6	3.5	2.5	0.6
TMDX TransMedics Group	2.3017 of 5 stars	2.4	1.0	0.0	2.7	2.5	1.9

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
INSP Inspire Medical Systems	2.73	Moderate Buy	$210.27	65.65% Upside
PLSE Pulse Biosciences	3.00	Buy	$22.00	45.70% Upside
SLNO Soleno Therapeutics	3.09	Buy	$108.70	24.66% Upside
TMDX TransMedics Group	2.89	Moderate Buy	$129.88	18.20% Upside

Current Analyst Ratings Breakdown

Latest PLSE, SLNO, TMDX, and INSP Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
7/15/2025	INSP Inspire Medical Systems	Morgan Stanley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Lower Price Target	Overweight ➝ Overweight	$200.00 ➝ $182.00
7/15/2025	TMDX TransMedics Group	Canaccord Genuity Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Buy ➝ Buy	$129.00 ➝ $142.00
7/11/2025	SLNO Soleno Therapeutics	Robert W. Baird Subscribe to MarketBeat All Access for the recommendation accuracy rating	Set Price Target	Outperform ➝ Outperform	$105.00 ➝ $121.00
7/7/2025	PLSE Pulse Biosciences	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Outperform	$22.00
6/23/2025	SLNO Soleno Therapeutics	Cowen Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy
6/23/2025	SLNO Soleno Therapeutics	TD Cowen Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy	$110.00
6/17/2025	TMDX TransMedics Group	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$130.00 ➝ $150.00
6/17/2025	TMDX TransMedics Group	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Hold ➝ Hold
6/4/2025	TMDX TransMedics Group	Piper Sandler Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Overweight ➝ Overweight	$125.00 ➝ $145.00
6/3/2025	TMDX TransMedics Group	Needham & Company LLC Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Hold ➝ Hold
5/9/2025	TMDX TransMedics Group	Oppenheimer Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Outperform ➝ Outperform	$125.00 ➝ $130.00

(Data available from 7/21/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
INSP Inspire Medical Systems	$802.80M	4.66	$1.71 per share	74.23	$23.01 per share	5.52
PLSE Pulse Biosciences	$700K	1,451.11	N/A	N/A	$1.87 per share	8.07
SLNO Soleno Therapeutics	N/A	N/A	N/A	N/A	$5.68 per share	N/A
TMDX TransMedics Group	$441.54M	8.42	$1.65 per share	66.78	$6.81 per share	16.14

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
INSP Inspire Medical Systems	$53.51M	$2.17	58.50	39.42	1.94	7.92%	10.00%	8.68%	8/5/2025 (Estimated)
PLSE Pulse Biosciences	-$53.58M	N/A	0.00	∞	N/A	N/A	-68.44%	-58.17%	8/14/2025 (Estimated)
SLNO Soleno Therapeutics	-$175.85M	-$4.62	N/A	N/A	N/A	N/A	-77.52%	-63.44%	8/6/2025 (Estimated)
TMDX TransMedics Group	$35.46M	$1.36	80.79	76.84	N/A	10.03%	21.88%	6.15%	7/30/2025 (Estimated)

Latest PLSE, SLNO, TMDX, and INSP Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/14/2025	Q2 2025	PLSE Pulse Biosciences	-$0.26	N/A	N/A	N/A	N/A	N/A
8/6/2025	Q2 2025	SLNO Soleno Therapeutics	-$0.85	N/A	N/A	N/A	$3.91 million	N/A
8/5/2025	Q2 2025	INSP Inspire Medical Systems	$0.22	N/A	N/A	N/A	$214.50 million	N/A
7/30/2025	Q2 2025	TMDX TransMedics Group	$0.48	N/A	N/A	N/A	$146.64 million	N/A
5/8/2025	Q1 2025	PLSE Pulse Biosciences	N/A	-$0.25	N/A	-$0.25	N/A	N/A
5/8/2025	Q1 2025	TMDX TransMedics Group	$0.29	$0.70	+$0.41	$0.70	$123.39 million	$143.54 million
5/7/2025	Q1 2025	SLNO Soleno Therapeutics	-$1.14	-$0.95	+$0.19	-$0.95	N/A	N/A
5/5/2025	Q1 2025	INSP Inspire Medical Systems	-$0.23	$0.10	+$0.33	$0.10	$194.89 million	$201.32 million

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
INSP Inspire Medical Systems	N/A	N/A	N/A	N/A	N/A
PLSE Pulse Biosciences	N/A	N/A	N/A	N/A	N/A
SLNO Soleno Therapeutics	N/A	N/A	N/A	N/A	N/A
TMDX TransMedics Group	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
INSP Inspire Medical Systems	N/A	9.01	7.44
PLSE Pulse Biosciences	N/A	15.58	15.58
SLNO Soleno Therapeutics	0.21	19.64	19.64
TMDX TransMedics Group	1.92	9.10	8.32

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
INSP Inspire Medical Systems	94.91%
PLSE Pulse Biosciences	76.95%
SLNO Soleno Therapeutics	97.42%
TMDX TransMedics Group	99.67%

Insider Ownership

Company	Insider Ownership
INSP Inspire Medical Systems	2.30%
PLSE Pulse Biosciences	71.50%
SLNO Soleno Therapeutics	6.40%
TMDX TransMedics Group	7.00%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
INSP Inspire Medical Systems	1,246	29.49 million	28.82 million	Optionable
PLSE Pulse Biosciences	140	67.27 million	19.17 million	Optionable
SLNO Soleno Therapeutics	30	50.39 million	47.17 million	Optionable
TMDX TransMedics Group	210	33.82 million	31.46 million	Optionable

PLSE, SLNO, TMDX, and INSP Headlines

Recent News About These Companies

Bank of New York Mellon Corp Decreases Stake in TransMedics Group, Inc. (NASDAQ:TMDX)

July 20 at 3:22 AM | marketbeat.com

Teacher Retirement System of Texas Invests $330,000 in TransMedics Group, Inc. (NASDAQ:TMDX)

July 19 at 3:07 AM | marketbeat.com

Canaccord Genuity Group Issues Positive Forecast for TransMedics Group (NASDAQ:TMDX) Stock Price

July 18 at 4:05 AM | americanbankingnews.com

TransMedics to Report Second Quarter 2025 Financial Results on July 30, 2025

July 16, 2025 | prnewswire.com

TransMedics Group (NASDAQ:TMDX) Given New $142.00 Price Target at Canaccord Genuity Group

July 15, 2025 | marketbeat.com

TransMedics: Q2 Analyst Estimates Will Fall Short

July 14, 2025 | seekingalpha.com

Emerald Advisers LLC Boosts Holdings in TransMedics Group, Inc. (NASDAQ:TMDX)

July 13, 2025 | marketbeat.com

Principal Financial Group Inc. Buys 5,480 Shares of TransMedics Group, Inc. (NASDAQ:TMDX)

July 13, 2025 | marketbeat.com

What is William Blair's Estimate for TMDX Q1 Earnings?

July 13, 2025 | americanbankingnews.com

Emerald Mutual Fund Advisers Trust Grows Stock Position in TransMedics Group, Inc. (NASDAQ:TMDX)

July 12, 2025 | marketbeat.com

TransMedics Group, Inc. (NASDAQ:TMDX) Given Consensus Rating of "Moderate Buy" by Analysts

July 12, 2025 | americanbankingnews.com

TransMedics Group, Inc. (NASDAQ:TMDX) Receives Average Rating of "Moderate Buy" from Analysts

July 12, 2025 | marketbeat.com

TransMedics Group (NASDAQ:TMDX) Stock Price Down 5.2% - What's Next?

July 11, 2025 | marketbeat.com

Brokers Issue Forecasts for TMDX Q1 Earnings

July 11, 2025 | marketbeat.com

TransMedics Group, Inc. (NASDAQ:TMDX) Stake Boosted by OneDigital Investment Advisors LLC

July 11, 2025 | marketbeat.com

New York State Teachers Retirement System Acquires 14,200 Shares of TransMedics Group, Inc. (NASDAQ:TMDX)

July 10, 2025 | marketbeat.com

Vontobel Holding Ltd. Makes New $291,000 Investment in TransMedics Group, Inc. (NASDAQ:TMDX)

July 9, 2025 | marketbeat.com

TransMedics Group, Inc. (NASDAQ:TMDX) Shares Purchased by Cambridge Investment Research Advisors Inc.

July 7, 2025 | marketbeat.com

TMDX - TransMedics Group Inc Executives - Morningstar

July 5, 2025 | morningstar.comM

TransMedics Group, Inc. (TMDX) Cash Flow - Yahoo Finance

July 4, 2025 | finance.yahoo.com

Is TransMedics Stock a Buy After Short-Seller Drama?

July 3, 2025 | fool.com

New MarketBeat Followers Over Time

Media Sentiment Over Time

PLSE, SLNO, TMDX, and INSP Company Descriptions

Inspire Medical Systems NYSE:INSP

$126.94 -1.03 (-0.80%)

Closing price 07/18/2025 03:59 PM Eastern

Extended Trading

$126.83 -0.11 (-0.09%)

As of 04:00 AM Eastern

Inspire Medical Systems, Inc., a medical technology company, focuses on the development and commercialization of minimally invasive solutions for patients with obstructive sleep apnea (OSA) in the United States and internationally. The company offers Inspire system, a neurostimulation technology that provides a safe and effective treatment for moderate to severe OSA. It also develops a novel, closed-loop solution that continuously monitors a patient's breathing and delivers mild hypoglossal nerve stimulation to maintain an open airway. The company was incorporated in 2007 and is headquartered in Golden Valley, Minnesota.

Pulse Biosciences NASDAQ:PLSE

$15.10 -0.55 (-3.51%)

Closing price 07/18/2025 04:00 PM Eastern

Extended Trading

$15.12 +0.02 (+0.13%)

As of 07/18/2025 04:27 PM Eastern

Pulse Biosciences, Inc. operates as a novel bioelectric medicine company. The company offers CellFX System, a tunable, software-enabled, and console-based platform that delivers nano second duration pulses of electrical energy to non-thermally clear targeted cells while sparing adjacent non-cellular tissue to treat a various medical condition by using its Nano-Pulse Stimulation technology. The company was formerly known as Electroblate, Inc. and changed its name to Pulse Biosciences, Inc. in December 2015. Pulse Biosciences, Inc. was incorporated in 2014 and is headquartered in Hayward, California.

Soleno Therapeutics NASDAQ:SLNO

$87.20 -0.44 (-0.50%)

Closing price 07/18/2025 04:00 PM Eastern

Extended Trading

$87.16 -0.05 (-0.05%)

As of 07/18/2025 04:32 PM Eastern

Soleno Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of novel therapeutics for the treatment of rare diseases. Its lead candidate is Diazoxide Choline Extended-Release tablets, a once-daily oral tablet, which is in Phase III clinical trials for the treatment of Prader-Willi Syndrome. The company was formerly known as Capnia, Inc. and changed its name to Soleno Therapeutics, Inc. in May 2017. Soleno Therapeutics, Inc. was incorporated in 1999 and is based in Redwood City, California.

TransMedics Group NASDAQ:TMDX

$109.88 -2.64 (-2.35%)

Closing price 07/18/2025 04:00 PM Eastern

Extended Trading

$110.68 +0.81 (+0.73%)

As of 05:54 AM Eastern

TransMedics Group, Inc., a commercial-stage medical technology company, engages in transforming organ transplant therapy for end-stage organ failure patients in the United States and internationally. The company offers Organ Care System (OCS), a portable organ perfusion, optimization, and monitoring system that utilizes its proprietary and customized technology to replicate near-physiologic conditions for donor organs outside of the human body. Its OCS includes OCS LUNG for the preservation of standard criteria donor lungs for double-lung transplantation; OCS Heart, a technology for preservation of DBD donor hearts deemed unsuitable due to limitations of cold storage and for ex vivo reanimation, functional monitoring, and beating-heart preservation of donation-after-circulatory-death hearts; and OCS Liver for the preservation of DBD and DCD of donor livers. The company also developed national OCS program, a turnkey solution for outsourced organ retrieval; and provides OCS organ management and logistics services, including aviation and ground transportation, and other coordination activity. The company was founded in 1998 and is headquartered in Andover, Massachusetts.

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Comparative Price Performance Over Time