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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:AXSM NASDAQ:NUVL NASDAQ:RNA NASDAQ:SDGR On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeAXSMAxsome Therapeutics$118.51+1.2%$106.36$75.56▼$139.13$5.85B0.51611,443 shs727,981 shsNUVLNuvalent$76.08+3.3%$78.55$55.53▼$113.51$5.49B1.3509,960 shs407,091 shsRNAAvidity Biosciences$46.35+3.8%$35.63$21.51▼$56.00$5.75B0.953.90 million shs1.89 million shsSDGRSchrodinger$20.32+3.8%$20.66$16.60▼$28.47$1.44B1.671.39 million shs1.90 million shs7 Stocks to Buy And Hold ForeverEnter your email address and we'll send you MarketBeat's list of seven stocks and why their long-term outlooks are very promising. Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceAXSMAxsome Therapeutics+1.17%+8.52%+11.42%+12.79%+34.81%NUVLNuvalent+3.30%+0.05%-5.47%+3.52%-7.96%RNAAvidity Biosciences+3.78%-0.26%+36.65%+51.57%+2.95%SDGRSchrodinger+3.78%+4.85%-11.77%-5.05%+1.14%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationAXSMAxsome Therapeutics4.8015 of 5 stars4.51.00.04.53.64.20.6NUVLNuvalent3.4047 of 5 stars4.51.00.00.03.33.30.0RNAAvidity Biosciences3.1733 of 5 stars4.52.00.00.03.90.80.0SDGRSchrodinger3.0989 of 5 stars3.33.00.00.02.43.30.6Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceAXSMAxsome Therapeutics 3.07Buy$178.0050.20% UpsideNUVLNuvalent 3.08Buy$118.9156.29% UpsideRNAAvidity Biosciences 3.06Buy$67.0044.55% UpsideSDGRSchrodinger 2.67Moderate Buy$27.8336.98% UpsideCurrent Analyst Ratings BreakdownLatest SDGR, RNA, AXSM, and NUVL Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/19/2025NUVLNuvalentPiper SandlerSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$112.008/18/2025SDGRSchrodingerMorgan StanleySubscribe to MarketBeat All Access for the recommendation accuracy ratingLower Price TargetEqual Weight ➝ Equal Weight$28.00 ➝ $19.008/15/2025SDGRSchrodingerCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingDowngradeBuy ➝ Neutral$35.00 ➝ $20.008/14/2025SDGRSchrodingerBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$25.008/14/2025SDGRSchrodingerBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$25.008/8/2025RNAAvidity BiosciencesWells Fargo & CompanySubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOverweight ➝ Overweight$70.00 ➝ $75.008/8/2025RNAAvidity BiosciencesBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOverweight ➝ Overweight$59.00 ➝ $62.008/8/2025RNAAvidity BiosciencesChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$75.008/5/2025AXSMAxsome TherapeuticsBank of AmericaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$173.00 ➝ $176.008/5/2025AXSMAxsome TherapeuticsRoyal Bank Of CanadaSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$184.00 ➝ $189.008/4/2025AXSMAxsome TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$150.00(Data available from 8/23/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookAXSMAxsome Therapeutics$385.69M15.33N/AN/A$1.46 per share81.17NUVLNuvalentN/AN/AN/AN/A$13.03 per shareN/ARNAAvidity Biosciences$10.90M547.06N/AN/A$9.27 per share5.00SDGRSchrodinger$207.54M7.21N/AN/A$4.66 per share4.36Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateAXSMAxsome Therapeutics-$287.22M-$5.07N/A42.02N/A-49.88%-283.22%-33.06%11/11/2025 (Estimated)NUVLNuvalent-$260.76M-$4.90N/AN/AN/AN/A-32.58%-30.14%11/11/2025 (Estimated)RNAAvidity Biosciences-$322.30M-$3.56N/AN/AN/A-4,247.77%-33.45%-30.22%11/6/2025 (Estimated)SDGRSchrodinger-$187.12M-$2.48N/AN/AN/A-76.22%-45.70%-24.81%11/11/2025 (Estimated)Latest SDGR, RNA, AXSM, and NUVL EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/7/2025Q2 2025NUVLNuvalent-$1.27-$1.31-$0.04-$1.39N/AN/A8/6/2025Q2 2025SDGRSchrodinger-$0.83-$0.59+$0.24-$0.59$52.03 million$54.76 million8/4/2025Q2 2025AXSMAxsome Therapeutics-$1.00-$0.92+$0.08-$0.97$140.02 million$150.04 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthAXSMAxsome TherapeuticsN/AN/AN/AN/AN/ANUVLNuvalentN/AN/AN/AN/AN/ARNAAvidity BiosciencesN/AN/AN/AN/AN/ASDGRSchrodingerN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioAXSMAxsome Therapeutics1.661.571.51NUVLNuvalentN/A13.5713.57RNAAvidity BiosciencesN/A9.269.26SDGRSchrodingerN/A3.303.30Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipAXSMAxsome Therapeutics81.49%NUVLNuvalent97.26%RNAAvidity BiosciencesN/ASDGRSchrodinger79.05%Insider OwnershipCompanyInsider OwnershipAXSMAxsome Therapeutics22.30%NUVLNuvalent10.20%RNAAvidity Biosciences3.83%SDGRSchrodinger21.00%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableAXSMAxsome Therapeutics38049.90 million38.77 millionOptionableNUVLNuvalent4072.11 million64.75 millionOptionableRNAAvidity Biosciences190128.65 million123.73 millionOptionableSDGRSchrodinger79073.61 million58.15 millionOptionableSDGR, RNA, AXSM, and NUVL HeadlinesRecent News About These CompaniesSchrödinger: A Complex Story With Many Moving PartsAugust 21 at 12:27 PM | seekingalpha.comPublic Sector Pension Investment Board Raises Stake in Schrodinger, Inc. $SDGRAugust 21 at 3:51 AM | marketbeat.comCetera Investment Advisers Takes Position in Schrodinger, Inc. $SDGRAugust 21 at 3:08 AM | marketbeat.comMorgan Stanley Cuts Schrodinger (NASDAQ:SDGR) Price Target to $19.00August 20 at 10:33 AM | marketbeat.comMorgan Stanley Issues Pessimistic Forecast for Schrodinger (NASDAQ:SDGR) Stock PriceAugust 20 at 2:25 AM | americanbankingnews.comWhat 4 Analyst Ratings Have To Say About SchrodingerAugust 18, 2025 | benzinga.comTocqueville Asset Management L.P. Sells 23,590 Shares of Schrodinger, Inc. (NASDAQ:SDGR)August 18, 2025 | marketbeat.comSchrodinger, Inc. (NASDAQ:SDGR) Receives $31.20 Consensus Price Target from AnalystsAugust 18, 2025 | americanbankingnews.comSchrodinger (NASDAQ:SDGR) Shares Gap Down - Should You Sell?August 17, 2025 | marketbeat.comSchrodinger (NASDAQ:SDGR) Upgraded to Strong-Buy at BarclaysAugust 17, 2025 | marketbeat.comTejara Capital Ltd Has $2.65 Million Holdings in Schrodinger, Inc. (NASDAQ:SDGR)August 17, 2025 | marketbeat.comSchrodinger (NASDAQ:SDGR) Shares Gap Down - Time to Sell?August 17, 2025 | americanbankingnews.comSchrodinger (NASDAQ:SDGR) Earns Overweight Rating from Analysts at BarclaysAugust 17, 2025 | americanbankingnews.comSchrodinger (SDGR) Gets a Buy from BarclaysAugust 16, 2025 | theglobeandmail.comCraig-Hallum Sticks to Its Buy Rating for Schrodinger (SDGR)August 16, 2025 | theglobeandmail.comSchrodinger (NASDAQ:SDGR) Sets New 12-Month Low - Here's What HappenedAugust 16, 2025 | marketbeat.comSchrodinger downgraded at Citi after clinical program exitAugust 16, 2025 | msn.comCitigroup Downgrades Schrödinger (SDGR)August 16, 2025 | msn.comSchrodinger, Inc. (NASDAQ:SDGR) Given Consensus Recommendation of "Moderate Buy" by BrokeragesAugust 16, 2025 | marketbeat.comSchrödinger Reports Inducement Grants under Nasdaq Listing Rule 5635(c)(4)August 15, 2025 | businesswire.comBarclays Initiates Coverage of Schrödinger (SDGR) with Overweight RecommendationAugust 15, 2025 | msn.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesDisney’s Iger-Led Turnaround Gains TractionBy Thomas Hughes | August 6, 2025Wall Street Has Left Intel for Dead—Here's Why You Shouldn’tBy Jeffrey Neal Johnson | August 8, 2025Intel's Turnaround Gains Credibility With Strong Q2 ReportBy Jeffrey Neal Johnson | July 25, 2025Viasat: Why a Wall of Cash Has Shorts Running for CoverBy Jeffrey Neal Johnson | August 8, 2025Why Byrna Could Be the Top Defense Stock to Watch NowBy Nathan Reiff | July 31, 2025SDGR, RNA, AXSM, and NUVL Company DescriptionsAxsome Therapeutics NASDAQ:AXSM$118.51 +1.37 (+1.17%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$118.47 -0.04 (-0.03%) As of 08/22/2025 07:55 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Axsome Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel therapies for central nervous system (CNS) disorders in the United States. The company's commercial product portfolio includes Auvelity (dextromethorphan-bupropion), a N-methyl-D-aspartate receptor antagonist with multimodal activity indicated for the treatment of major depressive disorder; and Sunosi (solriamfetol), a medication indicated to the treatment of excessive daytime sleepiness in patients with narcolepsy or obstructive sleep apnea. It is also developing AXS-05, which is in Phase III clinical trial to treat Alzheimer's disease agitation, as well as that has completed phase II clinical trial for the treatment of smoking cessation; AXS-07, an investigational medicine that has completed Phase III trials for the acute treatment of migraine; AXS-12, an investigational medicine, which is in Phase III trial to treat narcolepsy; AXS-14, a selective and potent norepinephrine reuptake inhibitor that has completed Phase III trial for the treatment of fibromyalgia and other conditions; and solriamfetol, a dual-acting dopamine and norepinephrine reuptake inhibitor, which has completed a Phase 2 trial for treating attention-deficit/hyperactivity disorder, and is in phase 2 major depressive, binge eating, and shift work disorder. Axsome Therapeutics, Inc. has a research collaboration agreement with Duke University for evaluating AXS-05 in smoking cessation. The company was incorporated in 2012 and is based in New York, New York.Nuvalent NASDAQ:NUVL$76.08 +2.43 (+3.30%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$76.08 0.00 (0.00%) As of 08/22/2025 05:25 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Nuvalent, Inc., a clinical stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the phase 2 portion of the ALKOVE-1 Phase 1/2 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR, which is expected to initiate phase 1 trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.Avidity Biosciences NASDAQ:RNA$46.35 +1.69 (+3.78%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$46.45 +0.10 (+0.22%) As of 08/22/2025 07:52 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Avidity Biosciences, Inc., a biopharmaceutical company, engages in the delivery of RNA therapeutics. It develops antibody oligonucleotide conjugates (AOC) that are designed to treat diseases previously untreatable with RNA therapeutics. The company's lead product candidate AOC 1001 for the treatment of myotonic dystrophy type 1, a rare monogenic muscle disease that is in phase 1/2 clinical trial. Its other products in pipeline include AOC 1044 for the treatment of duchenne muscular dystrophy, which is under phase 1/2 clinical development trial; and AOC 1020 to treat facioscapulohumeral muscular dystrophy that is in phase 1/2 clinical trial. The company is developing products for rare skeletal muscle and rare cardiac diseases. Avidity Biosciences, Inc. was incorporated in 2012 and is headquartered in San Diego, California.Schrodinger NASDAQ:SDGR$20.32 +0.74 (+3.78%) Closing price 08/22/2025 04:00 PM EasternExtended Trading$19.95 -0.37 (-1.82%) As of 08/22/2025 07:34 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Schrödinger, Inc., together with its subsidiaries, develops physics-based computational platform that enables discovery of novel molecules for drug development and materials applications. The company operates in two segments, Software and Drug Discovery. The Software segment is focused on licensing its software to transform molecular discovery for life sciences and materials science industries. The Drug Discovery segment focuses on building a portfolio of preclinical and clinical programs, internally and through collaborations. The company serves biopharmaceutical and industrial companies, academic institutions, and government laboratories worldwide. Schrödinger, Inc. was incorporated in 1990 and is based in New York, New York. 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