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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:OPT NASDAQ:ORKA NASDAQ:RAPP NASDAQ:TARA On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeOPTOpthea$3.41$3.41$1.79▼$6.30$524.83M1.17N/AN/AORKAOruka Therapeutics$14.33-1.6%$13.43$5.49▼$52.32$536.66M-0.35248,597 shs120,689 shsRAPPRapport Therapeutics$14.39+1.0%$13.58$6.43▼$29.74$525.02M0.62187,339 shs77,402 shsTARAProtara Therapeutics$3.04-0.3%$3.10$1.60▼$10.48$117.29M1.42329,809 shs214,058 shsReduce the RiskMarket downturns give many investors pause, and for good reason. Wondering how to offset this risk? Enter your email address to learn more about using beta to protect your portfolio.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceOPTOpthea0.00%0.00%0.00%0.00%+24.45%ORKAOruka Therapeutics-4.52%+4.37%+0.14%+37.62%+1,455,999,900.00%RAPPRapport Therapeutics-2.40%-8.37%-3.00%+41.83%-32.54%TARAProtara Therapeutics-5.28%-0.65%-0.97%-6.15%+43.19%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationOPTOpthea0.3657 of 5 stars1.10.00.00.02.10.80.6ORKAOruka Therapeutics2.5118 of 5 stars3.60.00.00.01.62.50.6RAPPRapport Therapeutics1.5396 of 5 stars3.50.00.00.01.11.70.6TARAProtara Therapeutics2.0822 of 5 stars3.61.00.00.02.60.80.6Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceOPTOpthea 2.17Hold$1.33-60.90% DownsideORKAOruka Therapeutics 3.20Buy$40.38181.75% UpsideRAPPRapport Therapeutics 3.00Buy$29.50105.07% UpsideTARAProtara Therapeutics 3.17Buy$19.60544.74% UpsideCurrent Analyst Ratings BreakdownLatest TARA, RAPP, OPT, and ORKA Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/18/2025ORKAOruka TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$45.008/12/2025ORKAOruka TherapeuticsWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform$40.008/6/2025RAPPRapport TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageBuy$31.007/23/2025ORKAOruka TherapeuticsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$45.007/21/2025ORKAOruka TherapeuticsWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform$40.007/8/2025RAPPRapport TherapeuticsJMP SecuritiesSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingMarket Outperform ➝ Market Outperform$28.005/22/2025ORKAOruka TherapeuticsBTIG ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageBuy5/22/2025ORKAOruka TherapeuticsBTIG ResearchSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeStrong-Buy$44.005/22/2025TARAProtara TherapeuticsJones TradingSubscribe to MarketBeat All Access for the recommendation accuracy ratingUpgradeStrong-Buy$21.00(Data available from 8/20/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookOPTOpthea$120K4,373.61N/AN/A($0.56) per share-6.09ORKAOruka TherapeuticsN/AN/AN/AN/A$9.10 per shareN/ARAPPRapport TherapeuticsN/AN/AN/AN/A$7.22 per shareN/ATARAProtara TherapeuticsN/AN/AN/AN/A$3.74 per shareN/ACompare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateOPTOpthea-$220.24MN/A0.00N/AN/AN/AN/AN/A8/29/2025 (Estimated)ORKAOruka Therapeutics-$83.72M-$2.81N/AN/AN/AN/A-26.26%-24.16%N/ARAPPRapport Therapeutics-$78.31M-$2.50N/AN/AN/AN/A-29.99%-28.64%11/6/2025 (Estimated)TARAProtara Therapeutics-$44.60M-$1.62N/AN/AN/AN/A-36.87%-33.85%N/ALatest TARA, RAPP, OPT, and ORKA EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/11/2025Q1 2025ORKAOruka Therapeutics-$0.48-$0.46+$0.02-$0.46N/AN/A8/11/2025Q2 2025TARAProtara Therapeutics-$0.43-$0.35+$0.08-$0.35N/AN/A8/7/2025Q2 2025RAPPRapport Therapeutics-$0.87-$0.75+$0.12-$0.75N/AN/ACompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthOPTOptheaN/AN/AN/AN/AN/AORKAOruka TherapeuticsN/AN/AN/AN/AN/ARAPPRapport TherapeuticsN/AN/AN/AN/AN/ATARAProtara TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioOPTOptheaN/A1.57N/AORKAOruka TherapeuticsN/A27.4227.42RAPPRapport TherapeuticsN/A22.7522.75TARAProtara TherapeuticsN/A12.8112.82Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipOPTOpthea55.95%ORKAOruka Therapeutics56.44%RAPPRapport TherapeuticsN/ATARAProtara Therapeutics38.13%Insider OwnershipCompanyInsider OwnershipOPTOpthea3.20%ORKAOruka Therapeutics24.69%RAPPRapport Therapeutics13.57%TARAProtara Therapeutics12.50%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableOPTOpthea8153.91 million148.99 millionNot OptionableORKAOruka TherapeuticsN/A37.45 million28.20 millionN/ARAPPRapport TherapeuticsN/A36.50 million31.55 millionN/ATARAProtara Therapeutics3038.58 million33.76 millionOptionableTARA, RAPP, OPT, and ORKA HeadlinesRecent News About These CompaniesProtara Therapeutics, Inc. (NASDAQ:TARA) Receives Consensus Recommendation of "Buy" from BrokeragesAugust 20 at 2:37 AM | marketbeat.comHC Wainwright Has Optimistic Outlook of TARA Q3 EarningsAugust 16, 2025 | marketbeat.comQ3 EPS Estimate for Protara Therapeutics Lifted by AnalystAugust 16, 2025 | americanbankingnews.comWe're Not Very Worried About Protara Therapeutics' (NASDAQ:TARA) Cash Burn RateAugust 13, 2025 | finance.yahoo.comProtara Therapeutics (NASDAQ:TARA) Announces Quarterly Earnings ResultsAugust 12, 2025 | marketbeat.comProtara Therapeutics Reports Q2 2025 Financial ResultsAugust 12, 2025 | msn.comProtara Beats Q2 Loss EstimatesAugust 11, 2025 | aol.comAProtara Therapeutics Announces Second Quarter 2025 Financial Results and Provides Business UpdateAugust 11, 2025 | globenewswire.comProtara Therapeutics, Inc. Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)August 1, 2025 | gurufocus.comProtara Therapeutics, Inc. Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)August 1, 2025 | globenewswire.comProtara Therapeutics (TARA) to Release Quarterly Earnings on TuesdayJuly 30, 2025 | marketbeat.comProtara Therapeutics (NASDAQ:TARA) Shares Up 11% - Still a Buy?July 22, 2025 | marketbeat.comProtara Therapeutics, Inc. Reports Inducement Grants Under Nasdaq Listing Rule 5635 (c) (4) - The Manila TimesJuly 2, 2025 | manilatimes.netMProtara Therapeutics, Inc. Reports Inducement Grants Under Nasdaq Listing Rule 5635 (c) (4) - MorningstarJuly 2, 2025 | morningstar.comMProtara Therapeutics, Inc. Added to Russell 3000® Index, Enhancing Visibility in Financial Community - NasdaqJuly 2, 2025 | nasdaq.comProtara Therapeutics, Inc. Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)July 1, 2025 | globenewswire.comProtara Therapeutics, Inc. Added to Russell 3000® Index, Enhancing Visibility in Financial CommunityJune 30, 2025 | quiverquant.comQProtara Therapeutics Announces Addition to the Russell 3000® IndexJune 30, 2025 | globenewswire.comProtara Therapeutics, Inc. (TARA) - Yahoo FinanceJune 26, 2025 | finance.yahoo.comRAPT Therapeutics Appoints Scott Braunstein, M.D. and Ashley Dombkowski, Ph.D. to Board of DirectorsJune 23, 2025 | quiverquant.comQProtara Therapeutics: Marching On To A Hopefully Eventful Back Half Of 2025June 14, 2025 | seekingalpha.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesRocket Lab: A Parabolic Run Meets a Healthy PullbackBy Ryan Hasson | July 23, 2025CrowdStrike Stock Slides—Is Growth Momentum Tapping Out?By Chris Markoch | August 7, 2025Palantir Bulls and Bears Set for an August Showdown By Chris Markoch | July 22, 2025Applied Digital: Why a Surge in Bullish Bets Signals a New Era By Jeffrey Neal Johnson | August 5, 2025CrowdStrike Stock Eyes Next Move With AI in FocusBy Chris Markoch | July 29, 2025TARA, RAPP, OPT, and ORKA Company DescriptionsOpthea NASDAQ:OPT$3.41 0.00 (0.00%) As of 08/19/2025Opthea Limited, a clinical stage biopharmaceutical company, engages in the development and commercialization of therapies primarily for eye disease in Australia. The company's development activities are based on the intellectual property portfolio covering Vascular Endothelial Growth Factors (VEGF) VEGF-C, VEGF-D, and VEGF Receptor-3 for the treatment of diseases associated with blood and lymphatic vessel growth, as well as vascular leakage. Its lead product candidate is Sozinibercept (OPT 302), a soluble form of vascular endothelial growth factor receptor-3 VEGFR-3, currently under Phase 3 clinical development as a novel therapy for wet age-related macular degeneration and diabetic macular edema. The company was formerly known as Circadian Technologies Limited and changed its name to Opthea Limited in December 2015. Opthea Limited was incorporated in 1984 and is based in South Yarra, Australia.Oruka Therapeutics NASDAQ:ORKA$14.33 -0.23 (-1.58%) Closing price 03:59 PM EasternExtended Trading$14.37 +0.04 (+0.28%) As of 04:04 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Oruka Therapeutics, Inc. is a biotechnology company, which focuses on developing novel monoclonal antibody therapeutics for PsO and other I&I indications. Its pipeline includes ORKA-001 and ORKA-002. The company is headquartered in Menlo Park, CA.Rapport Therapeutics NASDAQ:RAPP$14.38 +0.15 (+1.02%) Closing price 03:59 PM EasternExtended Trading$14.32 -0.07 (-0.49%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Rapport Therapeutics Inc. is a clinical-stage biotechnology company. It focused on discovery and development of transformational small molecule medicines for patients suffering from central nervous system disorders. Rapport Therapeutics Inc. is based in BOSTON.Protara Therapeutics NASDAQ:TARA$3.04 -0.01 (-0.33%) Closing price 03:59 PM EasternExtended Trading$3.02 -0.02 (-0.49%) As of 04:10 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Protara Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in advancing transformative therapies for the treatment of cancer and rare diseases. The company's lead program is TARA-002, an investigational cell therapy, which is in Phase II clinical trial for the treatment of non-muscle invasive bladder cancer and lymphatic malformations. It is also developing intravenous choline chloride, an investigational phospholipid substrate replacement therapy that is in Phase II clinical trial for patients receiving parenteral nutrition. The company is headquartered in New York, New York. 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