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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
$2.32
$2.59
$1.11
$10.54
$45.21M1.51248,686 shs119,687 shs
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
$0.69
-4.3%
$1.04
$0.11
$3.91
$44.47M10.91.37 million shs942,684 shs
Talphera, Inc. stock logo
TLPH
Talphera
$0.54
-0.9%
$0.45
$0.38
$1.19
$11.20M-0.093.36 million shs202,066 shs
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
$3.76
-8.7%
$2.19
$1.35
$26.83
$47M0.610.60 million shs897,594 shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
-1.69%-2.10%-12.27%-0.43%-73.37%
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
-0.75%+6.54%-24.53%+292.26%+72,449,900.00%
Talphera, Inc. stock logo
TLPH
Talphera
+0.76%+12.10%+22.74%+13.66%-41.95%
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
-2.60%+29.56%+114.58%+22.26%-80.10%
CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & Valuation
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
1.9479 of 5 stars
3.33.00.00.00.61.70.6
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
N/AN/AN/AN/AN/AN/AN/AN/A
Talphera, Inc. stock logo
TLPH
Talphera
2.6714 of 5 stars
3.85.00.00.02.60.00.0
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
4.0788 of 5 stars
3.52.00.04.62.51.70.6
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
2.60
Moderate Buy$18.00675.86% Upside
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
0.00
N/AN/AN/A
Talphera, Inc. stock logo
TLPH
Talphera
3.50
Strong Buy$5.00824.21% Upside
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
3.00
Buy$34.17808.69% Upside

Current Analyst Ratings Breakdown

Latest TLPH, ANVS, XFOR, and KLTO Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
8/29/2025
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
Stifel Nicolaus
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$30.00 ➝ $9.00
8/13/2025
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Set Price TargetBuy ➝ Buy$7.00 ➝ $3.50
8/8/2025
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
Zacks Research
Subscribe to MarketBeat All Access for the recommendation accuracy rating
UpgradeHold
6/9/2025
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
HC Wainwright
Subscribe to MarketBeat All Access for the recommendation accuracy rating
Lower Price TargetBuy ➝ Buy$30.00 ➝ $12.00
(Data available from 8/29/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
N/AN/AN/AN/A$0.94 per shareN/A
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
N/AN/AN/AN/A$0.17 per shareN/A
Talphera, Inc. stock logo
TLPH
Talphera
$650K17.08N/AN/A$0.32 per share1.69
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
$2.56M16.76N/AN/A$0.35 per share10.74
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
-$24.59M-$2.04N/AN/AN/AN/A-206.01%-158.26%11/14/2025 (Estimated)
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
-$6.15M-$0.45N/AN/AN/A-325.88%-242.15%N/A
Talphera, Inc. stock logo
TLPH
Talphera
-$13M-$0.40N/AN/AN/AN/A-152.38%-64.32%11/12/2025 (Estimated)
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
-$37.45M-$14.84N/AN/AN/A-311.15%-375.31%-72.87%11/12/2025 (Estimated)

Latest TLPH, ANVS, XFOR, and KLTO Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
8/18/2025Q2 2025
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
N/A-$0.12N/A-$0.12N/AN/A
8/14/2025Q2 2025
Talphera, Inc. stock logo
TLPH
Talphera
-$0.1150-$0.10+$0.0150-$0.10N/AN/A
8/12/2025Q2 2025
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
-$0.36-$0.32+$0.04-$0.32N/AN/A
8/8/2025Q2 2025
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
-$4.53-$3.47+$1.06-$3.47$1.62 million$1.97 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
N/AN/AN/AN/AN/A
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
N/AN/AN/AN/AN/A
Talphera, Inc. stock logo
TLPH
Talphera
N/AN/AN/AN/AN/A
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
N/A
7.65
7.65
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
N/A
135.73
135.73
Talphera, Inc. stock logo
TLPH
Talphera
N/A
2.93
2.93
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
19.10
3.19
3.05

Institutional Ownership

CompanyInstitutional Ownership
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
15.83%
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
20.07%
Talphera, Inc. stock logo
TLPH
Talphera
37.67%
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
72.03%

Insider Ownership

CompanyInsider Ownership
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
20.80%
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
26.70%
Talphera, Inc. stock logo
TLPH
Talphera
3.20%
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
2.37%
CompanyEmployeesShares OutstandingFree FloatOptionable
Annovis Bio, Inc. stock logo
ANVS
Annovis Bio
319.49 million15.43 millionOptionable
Klotho Neurosciences, Inc. stock logo
KLTO
Klotho Neurosciences
N/A61.37 million44.99 millionN/A
Talphera, Inc. stock logo
TLPH
Talphera
1920.52 million19.87 millionOptionable
X4 Pharmaceuticals, Inc. stock logo
XFOR
X4 Pharmaceuticals
8011.41 million11.14 millionOptionable

Recent News About These Companies

Brookline Capital Management Comments on XFOR Q3 Earnings
X4 Pharmaceuticals Closes $85M Private Placement Deal
X4 Pharmaceuticals, Inc. (XFOR) - Yahoo Finance
XFOR X4 Pharmaceuticals, Inc. - Seeking Alpha

New MarketBeat Followers Over Time

Media Sentiment Over Time

Annovis Bio stock logo

Annovis Bio NYSE:ANVS

$2.32 0.00 (0.00%)
Closing price 03:58 PM Eastern
Extended Trading
$2.32 0.00 (0.00%)
As of 06:35 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Annovis Bio, Inc., a clinical stage drug platform company, develops drugs to treat neurodegeneration. The company's lead product candidate is Buntanetap, which has completed three Phase 1/2 clinical trials for the treatment of Alzheimer's disease (AD), Parkinson's disease, and other chronic neurodegenerative diseases. It is also developing ANVS405, which is in Phase 2 and Phase 3 efficacy studies, an intravenous drug for protecting the brain after traumatic brain injury and/or stroke; and ANVS301, which is in Phase I clinical trials, an orally administered drug to increase cognitive capability in later stages of AD and dementia. The company was incorporated in 2008 and is based in Malvern, Pennsylvania.

Klotho Neurosciences stock logo

Klotho Neurosciences NASDAQ:KLTO

$0.69 -0.03 (-4.25%)
As of 04:00 PM Eastern

Klotho Neurosciences, Inc., a biopharmaceutical company, develops therapies for neurological and age-related disorders, and specialty diagnostics. Its products include cell and gene therapies to mitigate age-related pathologies, such as dementia symptoms, and Alzheimer and neuromuscular diseases; biologics/biosimilars in the treatment of cancer; and melanocortin receptors. The company has a strategic partnership with Japan's Okinawa Research Center for the research and development of Klotho gene therapy in enhancing longevity and reducing age-related diseases. The company was formerly known as Anew Medical, Inc. and changed its name to Klotho Neurosciences, Inc. in September 2024. Klotho Neurosciences, Inc. is based in Omaha, Nebraska.

Talphera stock logo

Talphera NASDAQ:TLPH

$0.54 0.00 (-0.86%)
Closing price 04:00 PM Eastern
Extended Trading
$0.53 -0.01 (-2.40%)
As of 06:27 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. Its lead product candidate is Niyad, a lyophilized formulation of nafamostat, which is under an investigational device exemption as an anticoagulant for the extracorporeal circuit. It is also developing LTX-608, an anti-inflammatory and antiviral potential for the treatment of multiple conditions, including disseminated intravascular coagulation (DIC), acute respiratory distress syndrome (ARDS), and acute pancreatitis; Fedsyra, a pre-filled ephedrine syringe; and PFS-02, a pre-filled phenylephrine syringe. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. The company was incorporated in 2005 and is headquartered in San Mateo, California.

X4 Pharmaceuticals stock logo

X4 Pharmaceuticals NASDAQ:XFOR

$3.76 -0.36 (-8.74%)
Closing price 04:00 PM Eastern
Extended Trading
$3.78 +0.03 (+0.66%)
As of 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

X4 Pharmaceuticals, Inc., a late-stage clinical biopharmaceutical company, focuses on the research, development, and commercialization of novel therapeutics for the treatment of rare diseases. Its lead product candidate is mavorixafor, a small molecule inhibitor of the chemokine receptor C-X-C chemokine receptor type 4 (CXCR4), which is in Phase III clinical trial for the treatment of patients with warts, hypogammaglobulinemia, infections, and myelokathexis syndrome; and Phase II clinical trial to treat congenital, idiopathic, or cyclic neutropenia. The company is also developing X4P-003, a CXCR4 antagonist for the treatment of CXCR4 dependent disorders and primary immunodeficiencies; and X4P-002, a CXCR4 antagonist for the treatment of blood-brain barrier diseases. It has a license agreement with Abbisko Therapeutics Co Ltd. to develop, manufacture, and commercialize mavorixafor in combination with checkpoint inhibitors or other agents in oncology indications. The company is headquartered in Boston, Massachusetts.