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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:CRNX NASDAQ:KYMR NASDAQ:RARE NASDAQ:TRVI On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCRNXCrinetics Pharmaceuticals$34.00+0.8%$30.93$24.10▼$62.53$3.18B0.281.07 million shs1.15 million shsKYMRKymera Therapeutics$46.99+1.7%$43.40$19.44▼$53.27$3.30B2.17598,355 shs579,312 shsRAREUltragenyx Pharmaceutical$30.31-2.9%$29.70$25.81▼$60.37$3.01B0.211.30 million shs1.39 million shsTRVITrevi Therapeutics$8.25-15.4%$7.36$2.36▼$9.92$1.19B0.712.75 million shs3.62 million shsOptions Trading Made Easy - Download NowLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. Click the link below to get your free copy.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCRNXCrinetics Pharmaceuticals+0.80%-4.52%+12.99%+7.02%-32.99%KYMRKymera Therapeutics+1.71%+8.00%+15.37%+0.06%+4.96%RAREUltragenyx Pharmaceutical-2.95%-4.75%+4.63%-19.15%-46.19%TRVITrevi Therapeutics-15.38%+17.69%+8.55%+35.47%+150.00%Compare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeCRNXCrinetics Pharmaceuticals$34.00+0.8%$30.93$24.10▼$62.53$3.18B0.281.07 million shs1.15 million shsKYMRKymera Therapeutics$46.99+1.7%$43.40$19.44▼$53.27$3.30B2.17598,355 shs579,312 shsRAREUltragenyx Pharmaceutical$30.31-2.9%$29.70$25.81▼$60.37$3.01B0.211.30 million shs1.39 million shsTRVITrevi Therapeutics$8.25-15.4%$7.36$2.36▼$9.92$1.19B0.712.75 million shs3.62 million shsOptions Trading Made Easy - Download NowLearn the basics of options trading and how to use them to boost returns and manage risk with this free report from MarketBeat. Click the link below to get your free copy.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceCRNXCrinetics Pharmaceuticals+0.80%-4.52%+12.99%+7.02%-32.99%KYMRKymera Therapeutics+1.71%+8.00%+15.37%+0.06%+4.96%RAREUltragenyx Pharmaceutical-2.95%-4.75%+4.63%-19.15%-46.19%TRVITrevi Therapeutics-15.38%+17.69%+8.55%+35.47%+150.00%Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceCRNXCrinetics Pharmaceuticals 2.78Moderate Buy$68.86102.52% UpsideKYMRKymera Therapeutics 3.06Buy$58.7625.06% UpsideRAREUltragenyx Pharmaceutical 2.92Moderate Buy$81.50168.89% UpsideTRVITrevi Therapeutics 3.13Buy$21.75163.64% UpsideCurrent Analyst Ratings BreakdownLatest TRVI, CRNX, KYMR, and RARE Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails9/9/2025RAREUltragenyx PharmaceuticalHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingBuy$80.009/5/2025RAREUltragenyx PharmaceuticalCantor FitzgeraldSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingReiterated RatingOverweight$105.008/21/2025TRVITrevi TherapeuticsMorgan StanleySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingInitiated CoverageOverweight$18.008/11/2025CRNXCrinetics PharmaceuticalsJMP SecuritiesSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetMarket Outperform$90.00 ➝ $86.008/8/2025RAREUltragenyx PharmaceuticalCanaccord Genuity GroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$136.00 ➝ $128.008/8/2025TRVITrevi TherapeuticsRaymond James FinancialSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetStrong-Buy$29.00 ➝ $27.008/8/2025TRVITrevi TherapeuticsNeedham & Company LLCSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetBuy$24.00 ➝ $22.008/6/2025RAREUltragenyx PharmaceuticalCantor FitzgeraldSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingLower Price TargetOverweight$112.00 ➝ $105.007/30/2025KYMRKymera TherapeuticsB. RileySubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeStrong-Buy$60.007/28/2025RAREUltragenyx PharmaceuticalHC WainwrightSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeBuy$80.007/15/2025KYMRKymera TherapeuticsThe Goldman Sachs GroupSubscribe to MarketBeat All Access for the firm's recommendation accuracy ratingUpgradeStrong-Buy(Data available from 9/13/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookCRNXCrinetics Pharmaceuticals$1.39M2,300.28N/AN/A$14.29 per share2.38KYMRKymera Therapeutics$44.71M75.14N/AN/A$12.90 per share3.64RAREUltragenyx Pharmaceutical$560.23M5.21N/AN/A$2.76 per share10.98TRVITrevi TherapeuticsN/AN/AN/AN/A$1.30 per shareN/ACompare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateCRNXCrinetics Pharmaceuticals-$298.41M-$4.11N/AN/AN/AN/A-32.28%-29.45%11/11/2025 (Estimated)KYMRKymera Therapeutics-$223.86M-$3.47N/AN/AN/A-616.03%-31.60%-27.12%10/30/2025 (Estimated)RAREUltragenyx Pharmaceutical-$569.18M-$5.53N/AN/AN/A-87.34%-237.48%-37.66%11/4/2025 (Estimated)TRVITrevi Therapeutics-$47.91M-$0.42N/AN/AN/AN/A-41.44%-38.21%11/5/2025 (Estimated)Latest TRVI, CRNX, KYMR, and RARE EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/11/2025Q2 2025KYMRKymera Therapeutics-$0.83-$0.95-$0.12-$0.95$17.37 million$11.48 million8/7/2025Q2 2025CRNXCrinetics Pharmaceuticals-$1.13-$1.23-$0.10-$1.23$0.52 million$1.03 million8/7/2025Q2 2025TRVITrevi Therapeutics-$0.10-$0.09+$0.01-$0.09N/AN/A8/5/2025Q2 2025RAREUltragenyx Pharmaceutical-$1.27-$1.17+$0.10-$1.17$161.37 million$166.50 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthCRNXCrinetics PharmaceuticalsN/AN/AN/AN/AN/AKYMRKymera TherapeuticsN/AN/AN/AN/AN/ARAREUltragenyx PharmaceuticalN/AN/AN/AN/AN/ATRVITrevi TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioCRNXCrinetics PharmaceuticalsN/A17.8017.80KYMRKymera TherapeuticsN/A8.328.32RAREUltragenyx PharmaceuticalN/A2.452.30TRVITrevi TherapeuticsN/A22.4222.42Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipCRNXCrinetics Pharmaceuticals98.51%KYMRKymera TherapeuticsN/ARAREUltragenyx Pharmaceutical97.67%TRVITrevi Therapeutics95.76%Insider OwnershipCompanyInsider OwnershipCRNXCrinetics Pharmaceuticals4.60%KYMRKymera Therapeutics16.01%RAREUltragenyx Pharmaceutical5.50%TRVITrevi Therapeutics18.30%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableCRNXCrinetics Pharmaceuticals21094.18 million89.84 millionOptionableKYMRKymera Therapeutics17071.50 million60.05 millionOptionableRAREUltragenyx Pharmaceutical1,29496.37 million91.07 millionOptionableTRVITrevi Therapeutics20121.78 million99.49 millionOptionableTRVI, CRNX, KYMR, and RARE HeadlinesRecent News About These CompaniesTrevi Therapeutics (NASDAQ:TRVI) Sees Strong Trading Volume - Still a Buy?3 hours ago | marketbeat.comFred Alger Management LLC Invests $482,000 in Trevi Therapeutics, Inc. $TRVISeptember 13 at 4:08 AM | marketbeat.comSiren L.L.C. Sells 42,267 Shares of Trevi Therapeutics, Inc. $TRVISeptember 13 at 3:12 AM | marketbeat.comTrevi Therapeutics (NASDAQ:TRVI) Hits New 12-Month High - Should You Buy?September 12 at 12:29 PM | marketbeat.comBrokerages Set Trevi Therapeutics, Inc. (NASDAQ:TRVI) Target Price at $21.75September 12 at 2:33 AM | americanbankingnews.comHaduvio Opportunity Positions Trevi (TRVI) for Multibagger Gains, Says Morgan StanleySeptember 11 at 8:11 AM | msn.comTrevi Therapeutics, Inc. $TRVI Stock Position Raised by Acorn Capital Advisors LLCSeptember 11 at 7:07 AM | marketbeat.comExome Asset Management LLC Takes $1.03 Million Position in Trevi Therapeutics, Inc. $TRVISeptember 11 at 6:17 AM | marketbeat.comOctagon Capital Advisors LP Makes New $20.90 Million Investment in Trevi Therapeutics, Inc. $TRVISeptember 11 at 6:03 AM | marketbeat.comTrevi Therapeutics, Inc. (NASDAQ:TRVI) Given Consensus Rating of "Buy" by AnalystsSeptember 11 at 4:55 AM | marketbeat.comTrevi Therapeutics (NASDAQ:TRVI) Trading 8.9% Higher - Here's WhySeptember 10 at 5:42 PM | marketbeat.comAdage Capital Partners GP L.L.C. Reduces Holdings in Trevi Therapeutics, Inc. $TRVISeptember 10 at 3:44 AM | marketbeat.comTrevi Therapeutics, Inc. (TRVI) Presents At Morgan Stanley 23rd Annual Global Healthcare Conference (Transcript)September 9, 2025 | seekingalpha.comPolar Asset Management Partners Inc. Acquires Shares of 64,050 Trevi Therapeutics, Inc. $TRVISeptember 9, 2025 | marketbeat.comTrevi Therapeutics, Inc. $TRVI Stock Holdings Boosted by Cubist Systematic Strategies LLCSeptember 9, 2025 | marketbeat.comTrevi Therapeutics, Inc. $TRVI Holdings Lifted by Raymond James Financial Inc.September 9, 2025 | marketbeat.comAlly Bridge Group NY LLC Sells 95,270 Shares of Trevi Therapeutics, Inc. $TRVISeptember 5, 2025 | marketbeat.comTrevi Therapeutics, Inc. $TRVI Stock Position Lifted by Panagora Asset Management Inc.September 5, 2025 | marketbeat.comTrevi Therapeutics, Inc. $TRVI Shares Bought by MPM Bioimpact LLCSeptember 4, 2025 | marketbeat.comFrazier Life Sciences Management L.P. Sells 405,365 Shares of Trevi Therapeutics, Inc. $TRVISeptember 4, 2025 | marketbeat.comBraidwell LP Takes Position in Trevi Therapeutics, Inc. $TRVISeptember 3, 2025 | marketbeat.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesBuffett Makes Big Moves Outside of UNH: A Buy and Sell BreakdownBy Leo Miller | August 18, 20253 Robotics Stocks at the Heart of the Robotics RevolutionBy Chris Markoch | August 21, 2025NIO Just Got Its Second Upgrade of the Month, and It’s BigBy Sam Quirke | August 28, 20255 High Short-Interest Stocks to Buy Before NovemberBy Thomas Hughes | August 20, 2025Energy Fuels: Is This America's Most Strategic Stock?By Jeffrey Neal Johnson | September 6, 2025TRVI, CRNX, KYMR, and RARE Company DescriptionsCrinetics Pharmaceuticals NASDAQ:CRNX$34.00 +0.27 (+0.80%) Closing price 09/12/2025 04:00 PM EasternExtended Trading$34.62 +0.63 (+1.84%) As of 09/12/2025 07:59 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Crinetics Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutics for rare endocrine diseases and endocrine-related tumors. The company's lead product candidate is paltusotine, an oral selective nonpeptide somatostatin receptor type 2 agonist, which is in Phase 3 trial for the treatment of acromegaly; and Phase 2 trial for treating carcinoid syndrome associated with neuroendocrine tumors. It is also developing CRN04894, an investigational oral nonpeptide product candidate to antagonize the adrenocorticotrophic hormone (ACTH) receptor that has completed a Phase 1 study for the treatment of diseases caused by excess ACTH, including congenital adrenal hyperplasia and Cushing's disease. In addition, the company is developing antagonists of the parathyroid hormone (PTH) receptor for the treatment of primary hyperparathyroidism and humoral hypercalcemia of malignancy, and other diseases of excess PTH; identified investigational orally available somatostatin receptor type 3 targeted nonpeptide agonists for the treatment of autosomal dominant polycystic kidney disease; and developing thyroid-stimulating hormone receptor antagonists for the treatment of graves' disease and thyroid eye disease, as well as Oral GLP-1 and GIP nonpeptides for the treatment of diabetes and obesity. Crinetics Pharmaceuticals, Inc. was incorporated in 2008 and is headquartered in San Diego, California.Kymera Therapeutics NASDAQ:KYMR$46.99 +0.79 (+1.71%) Closing price 09/12/2025 04:00 PM EasternExtended Trading$47.75 +0.76 (+1.62%) As of 09/12/2025 07:08 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Kymera Therapeutics, Inc., a biopharmaceutical company, focuses on discovering and developing novel small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. It engages in developing IRAK4 program, which is in Phase II clinical trial for the treatment of immunology-inflammation diseases, including hidradenitis suppurativa, atopic dermatitis; STAT3 program for the treatment of hematologic malignancies and solid tumors, as well as autoimmune diseases and fibrosis; and MDM2 program to treat hematological malignancies and solid tumors. The company develops STAT6, a Type 2 inflammation in allergic diseases; and TYK2, a treatment for inflammatory bowel disease, psoriasis, psoriatic arthritis, and lupus. The company was incorporated in 2015 and is headquartered in Watertown, Massachusetts.Ultragenyx Pharmaceutical NASDAQ:RARE$30.31 -0.92 (-2.95%) Closing price 09/12/2025 04:00 PM EasternExtended Trading$30.68 +0.37 (+1.20%) As of 09/12/2025 06:46 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Ultragenyx Pharmaceutical Inc., a biopharmaceutical company, focuses on the identification, acquisition, development, and commercialization of novel products for the treatment of rare and ultra-rare genetic diseases in North America, Latin America, Japan, Europe, and internationally. Its biologic products include Crysvita (burosumab), an antibody targeting fibroblast growth factor 23 for the treatment of X-linked hypophosphatemia, as well as tumor-induced osteomalacia; Mepsevii, an enzyme replacement therapy for the treatment of children and adults with Mucopolysaccharidosis VII; Dojolvi for treating long-chain fatty acid oxidation disorders; and Evkeeza (evinacumab) for the treatment of homozygous familial hypercholesterolemia. The company's products candidatures include DTX401, an adeno-associated virus 8 (AAV8) gene therapy clinical candidate for the treatment of patients with glycogen storage disease type Ia; DTX301, an AAV8 gene therapy for the treatment of patients with ornithine transcarbamylase; UX143, a human monoclonal antibody for the treatment of osteogenesis imperfecta; GTX-102, an antisense oligonucleotide for the treatment of Angelman syndrome; UX111, an AAV9 gene therapy product candidate for the treatment of patients with Sanfilippo syndrome type A, or MPS IIIA, a rare lysosomal storage disease; UX701, for the treatment of Wilson disease; and UX053 for the treatment of glycogen storage disease type III. Ultragenyx Pharmaceutical Inc. has collaboration and license agreement with Kyowa Kirin Co., Ltd.; Saint Louis University; Baylor Research Institute; REGENXBIO Inc.; Bayer Healthcare LLC; GeneTx; Mereo; University of Pennsylvania; Arcturus Therapeutics Holdings Inc.; Solid Biosciences Inc.; Regeneron; Abeona; and Daiichi Sankyo Co., Ltd. The company was incorporated in 2010 and is headquartered in Novato, California.Trevi Therapeutics NASDAQ:TRVI$8.25 -1.50 (-15.38%) Closing price 09/12/2025 04:00 PM EasternExtended Trading$8.18 -0.06 (-0.79%) As of 09/12/2025 07:53 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Trevi Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapy Haduvio for the treatment of chronic cough in idiopathic pulmonary fibrosis (IPF) and refractory chronic cough (RCC) conditions targeting the central and peripheral nervous systems. The company is developing Haduvio, an oral extended-release formulation of nalbuphine, which is in phase 2b Cough Reduction in IPF with nalbuphine ER (CORAL) clinical trial for treatment of chronic cough in patients with IPF; phase 2a Refractory Chronic Cough Improvement Via NAL ER (RIVER) clinical trial for reducing chronic cough in RCC patients; phase 2 clinical trial in patients with pruritus; phase 2b/3 clinical trial in patients with prurigo nodularis. It has a license agreement with Endo Pharmaceuticals Inc. to develop and commercialize products incorporating nalbuphine hydrochloride in any formulation. The company was incorporated in 2011 and is headquartered in New Haven, Connecticut. 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