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Stocks to Compare Sections All Sections Selected Performance Chart Price & Volume MarketRank Analyst Ratings Sales & Book Value Profitability & Earnings Dividends Debt Ownership Miscellaneous Headlines About Compare NASDAQ:NUVL NASDAQ:RNA NASDAQ:RYTM NASDAQ:TVTX On This Page Performance ChartPrice & VolumeMarketRank™Analyst RatingsSales & Book ValueProfitability & EarningsDividendsDebtOwnershipMiscellaneousHeadlinesAbout Comparison Ideas Stock Ideas Comparative Price Performance Over Time1 day7 days30 days90 days365 daysCompare Price & VolumeCompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's VolumeNUVLNuvalent$76.08+3.3%$78.60$55.53▼$113.51$5.49B1.3538,811 shs391,799 shsRNAAvidity Biosciences$46.35+3.8%$35.33$21.51▼$56.00$5.96B0.951.84 million shs1.89 million shsRYTMRhythm Pharmaceuticals$103.27+1.6%$81.14$44.31▼$104.87$6.86B2.38665,837 shs711,778 shsTVTXTravere Therapeutics$17.92+0.7%$15.98$8.50▼$25.29$1.60B0.741.65 million shs1.91 million shs(Almost) Everything You Need To Know About The EV MarketLooking to profit from the electric vehicle mega-trend? Enter your email address and we'll send you our list of which EV stocks show the most long-term potential.Get This Free ReportCompare Price PerformanceCompany1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year PerformanceNUVLNuvalent+0.56%-4.10%-8.71%+0.22%-10.90%RNAAvidity Biosciences+0.72%-3.06%+33.19%+46.04%-0.80%RYTMRhythm Pharmaceuticals+3.02%+5.39%+15.78%+63.05%+124.06%TVTXTravere Therapeutics-1.00%-2.41%+13.60%+12.31%+104.72%Compare MarketRank™CompanyOverall ScoreAnalyst's OpinionShort Interest ScoreDividend StrengthESG ScoreNews and Social Media SentimentCompany OwnershipEarnings & ValuationNUVLNuvalent3.3659 of 5 stars4.51.00.00.03.23.30.0RNAAvidity Biosciences3.1393 of 5 stars4.52.00.00.03.90.80.0RYTMRhythm Pharmaceuticals3.7389 of 5 stars2.53.00.04.33.30.80.6TVTXTravere Therapeutics2.5733 of 5 stars3.43.00.00.02.70.80.6Compare Analyst ForecastsCompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current PriceNUVLNuvalent 3.08Buy$118.9156.29% UpsideRNAAvidity Biosciences 3.06Buy$67.0044.55% UpsideRYTMRhythm Pharmaceuticals 3.07Buy$101.57-1.64% DownsideTVTXTravere Therapeutics 2.87Moderate Buy$32.2179.77% UpsideCurrent Analyst Ratings BreakdownLatest TVTX, RYTM, RNA, and NUVL Analyst RatingsDateCompanyBrokerageActionRatingPrice TargetDetails8/19/2025NUVLNuvalentPiper SandlerSubscribe to MarketBeat All Access for the recommendation accuracy ratingInitiated CoverageOverweight$112.008/10/2025TVTXTravere TherapeuticsCitigroupSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy8/8/2025RNAAvidity BiosciencesWells Fargo & CompanySubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOverweight ➝ Overweight$70.00 ➝ $75.008/8/2025RNAAvidity BiosciencesBarclaysSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOverweight ➝ Overweight$59.00 ➝ $62.008/8/2025RNAAvidity BiosciencesChardan CapitalSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingBuy ➝ Buy$75.008/7/2025TVTXTravere TherapeuticsScotiabankSubscribe to MarketBeat All Access for the recommendation accuracy ratingReiterated RatingOutperform ➝ Outperform8/7/2025RYTMRhythm PharmaceuticalsHC WainwrightSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$80.00 ➝ $100.008/7/2025TVTXTravere TherapeuticsScotiabankSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetSector Outperform ➝ Sector Outperform$30.00 ➝ $31.008/7/2025TVTXTravere TherapeuticsWedbushSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetOutperform ➝ Outperform$30.00 ➝ $32.008/6/2025RYTMRhythm PharmaceuticalsGuggenheimSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetBuy ➝ Buy$119.00 ➝ $120.008/6/2025RYTMRhythm PharmaceuticalsJMP SecuritiesSubscribe to MarketBeat All Access for the recommendation accuracy ratingBoost Price TargetMarket Outperform ➝ Market Outperform$130.00 ➝ $135.00(Data available from 8/22/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)Compare Sales & Book ValueCompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/BookNUVLNuvalentN/AN/AN/AN/A$13.03 per shareN/ARNAAvidity Biosciences$10.90M547.06N/AN/A$9.27 per share5.00RYTMRhythm Pharmaceuticals$156.29M43.89N/AN/A($0.18) per share-573.72TVTXTravere Therapeutics$233.18M6.85N/AN/A$0.37 per share48.43Compare Profitability & EarningsCompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings DateNUVLNuvalent-$260.76M-$4.90N/AN/AN/AN/A-32.58%-30.14%N/ARNAAvidity Biosciences-$322.30M-$3.56N/AN/AN/A-4,247.77%-33.45%-30.22%11/6/2025 (Estimated)RYTMRhythm Pharmaceuticals-$260.60M-$3.01N/AN/AN/A-117.13%-1,831.43%-48.33%11/4/2025 (Estimated)TVTXTravere Therapeutics-$321.55M-$2.04N/AN/AN/A-50.64%-717.68%-30.69%10/30/2025 (Estimated)Latest TVTX, RYTM, RNA, and NUVL EarningsDateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails8/7/2025Q2 2025NUVLNuvalent-$1.27-$1.31-$0.04-$1.39N/AN/A8/6/2025Q2 2025TVTXTravere Therapeutics-$0.28-$0.14+$0.14-$0.14$100.18 million$94.84 million8/5/2025Q2 2025RYTMRhythm Pharmaceuticals-$0.66-$0.75-$0.09-$0.75$43.72 million$48.50 millionCompare DividendsCompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive GrowthNUVLNuvalentN/AN/AN/AN/AN/ARNAAvidity BiosciencesN/AN/AN/AN/AN/ARYTMRhythm PharmaceuticalsN/AN/AN/AN/AN/ATVTXTravere TherapeuticsN/AN/AN/AN/AN/ACompare DebtCompanyDebt-to-Equity RatioCurrent RatioQuick RatioNUVLNuvalentN/A13.5713.57RNAAvidity BiosciencesN/A9.269.26RYTMRhythm PharmaceuticalsN/A2.792.64TVTXTravere Therapeutics9.502.001.98Compare OwnershipInstitutional OwnershipCompanyInstitutional OwnershipNUVLNuvalent97.26%RNAAvidity BiosciencesN/ARYTMRhythm PharmaceuticalsN/ATVTXTravere TherapeuticsN/AInsider OwnershipCompanyInsider OwnershipNUVLNuvalent10.20%RNAAvidity Biosciences3.83%RYTMRhythm Pharmaceuticals6.10%TVTXTravere Therapeutics4.19%Compare Miscellaneous StatsCompanyEmployeesShares OutstandingFree FloatOptionableNUVLNuvalent4072.11 million64.75 millionOptionableRNAAvidity Biosciences190128.65 million123.73 millionOptionableRYTMRhythm Pharmaceuticals14066.42 million62.37 millionOptionableTVTXTravere Therapeutics46089.14 million85.40 millionOptionableTVTX, RYTM, RNA, and NUVL HeadlinesRecent News About These CompaniesAberdeen Group plc Raises Stock Holdings in Travere Therapeutics, Inc. $TVTXAugust 22 at 4:18 AM | marketbeat.comNuveen LLC Makes New Investment in Travere Therapeutics, Inc. $TVTXAugust 20 at 3:51 AM | marketbeat.comWall Street Zen Upgrades Travere Therapeutics (NASDAQ:TVTX) to "Buy"August 19 at 2:25 AM | americanbankingnews.comCiti Lifts Travere Therapeutics (TVTX) PT to $34 on Strong Q2 and Upcoming FDA CatalystsAugust 18, 2025 | msn.comWall Street Zen Upgrades Travere Therapeutics (NASDAQ:TVTX) to BuyAugust 17, 2025 | marketbeat.comAnalysts Set Travere Therapeutics, Inc. (NASDAQ:TVTX) Price Target at $32.21August 15, 2025 | americanbankingnews.comInformed Momentum Co LLC Invests $2.69 Million in Travere Therapeutics, Inc. (NASDAQ:TVTX)August 14, 2025 | marketbeat.comConnor Clark & Lunn Investment Management Ltd. Boosts Holdings in Travere Therapeutics, Inc. (NASDAQ:TVTX)August 13, 2025 | marketbeat.comTVTX FY2025 EPS Forecast Boosted by Cantor FitzgeraldAugust 12, 2025 | americanbankingnews.comTravere Therapeutics, Inc. (NASDAQ:TVTX) Given Consensus Rating of "Moderate Buy" by AnalystsAugust 12, 2025 | marketbeat.comCantor Fitzgerald Issues Positive Outlook for TVTX EarningsAugust 11, 2025 | marketbeat.comTravere Therapeutics price target raised to $32 from $30 at WedbushAugust 8, 2025 | finance.yahoo.comTravere Therapeutics (NASDAQ:TVTX) Given New $31.00 Price Target at ScotiabankAugust 8, 2025 | marketbeat.comWedbush Boosts Travere Therapeutics (NASDAQ:TVTX) Price Target to $32.00August 8, 2025 | marketbeat.comTravere Therapeutics shares rise as Q2 results top expectationsAugust 7, 2025 | investing.comTravere Therapeutics Reports Strong Q2 2025 GrowthAugust 7, 2025 | msn.comTravere Therapeutics, Inc. (TVTX) Q2 2025 Earnings Call TranscriptAugust 6, 2025 | seekingalpha.comTravere Therapeutics, Inc. 2025 Q2 - Results - Earnings Call PresentationAugust 6, 2025 | seekingalpha.comHere's What Key Metrics Tell Us About Travere (TVTX) Q2 EarningsAugust 6, 2025 | zacks.comTravere Therapeutics (TVTX) Reports Q2 Loss, Tops Revenue EstimatesAugust 6, 2025 | zacks.comEarnings Preview: Travere TherapeuticsAugust 5, 2025 | benzinga.comNew MarketBeat Followers Over TimeMedia Sentiment Over Time Top HeadlinesView All HeadlinesDisney’s Iger-Led Turnaround Gains TractionBy Thomas Hughes | August 6, 2025Intel's Turnaround Gains Credibility With Strong Q2 ReportBy Jeffrey Neal Johnson | July 25, 2025Wall Street Has Left Intel for Dead—Here's Why You Shouldn’tBy Jeffrey Neal Johnson | August 8, 2025Why Byrna Could Be the Top Defense Stock to Watch NowBy Nathan Reiff | July 31, 2025Viasat: Why a Wall of Cash Has Shorts Running for CoverBy Jeffrey Neal Johnson | August 8, 2025TVTX, RYTM, RNA, and NUVL Company DescriptionsNuvalent NASDAQ:NUVL$76.08 +2.43 (+3.30%) Closing price 04:00 PM EasternExtended Trading$76.08 0.00 (0.00%) As of 04:30 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Nuvalent, Inc., a clinical stage biopharmaceutical company, engages in the development of therapies for patients with cancer. Its lead product candidates are NVL-520, a novel ROS1-selective inhibitor to address the clinical challenges of emergent treatment resistance, central nervous system (CNS)-related adverse events, and brain metastases that may limit the use of ROS1 tyrosine kinase inhibitors (TKIs) for patients with ROS proto-oncogene 1 (ROS1)-positive non-small cell lung cancer (NSCLC) which is under the phase 2 portion of the ARROS-1 Phase 1/2 clinical trial; NVL-655, a brain-penetrant ALK-selective inhibitor, to address the clinical challenges of emergent treatment resistance, CNS-related adverse events, and brain metastases that might limit the use of first-, second-, and third-generation ALK inhibitors that is under the phase 2 portion of the ALKOVE-1 Phase 1/2 clinical trial; and NVL-330, a brain-penetrant human epidermal growth factor receptor 2 (HER2)-selective inhibitor designed to treat tumors driven by HER2ex20, brain metastases, and avoiding treatment-limiting adverse events including due to off-target inhibition of wild-type EGFR, which is expected to initiate phase 1 trial. The company was incorporated in 2017 and is headquartered in Cambridge, Massachusetts.Avidity Biosciences NASDAQ:RNA$46.35 +1.69 (+3.78%) Closing price 04:00 PM EasternExtended Trading$47.00 +0.64 (+1.39%) As of 04:35 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Avidity Biosciences, Inc., a biopharmaceutical company, engages in the delivery of RNA therapeutics. It develops antibody oligonucleotide conjugates (AOC) that are designed to treat diseases previously untreatable with RNA therapeutics. The company's lead product candidate AOC 1001 for the treatment of myotonic dystrophy type 1, a rare monogenic muscle disease that is in phase 1/2 clinical trial. Its other products in pipeline include AOC 1044 for the treatment of duchenne muscular dystrophy, which is under phase 1/2 clinical development trial; and AOC 1020 to treat facioscapulohumeral muscular dystrophy that is in phase 1/2 clinical trial. The company is developing products for rare skeletal muscle and rare cardiac diseases. Avidity Biosciences, Inc. was incorporated in 2012 and is headquartered in San Diego, California.Rhythm Pharmaceuticals NASDAQ:RYTM$103.27 +1.59 (+1.56%) Closing price 04:00 PM EasternExtended Trading$103.25 -0.02 (-0.02%) As of 04:39 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Rhythm Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the rare neuroendocrine diseases. The company's lead product candidate is IMCIVREE (setmelanotide), a rare melanocortin-4 receptor for the treatment of pro-opiomelanocortin (POMC), proprotein convertase subtilisin/kexin type 1, leptin receptor (LEPR) deficiency obesity, and Bardet-Biedl and Alström syndrome. It is in Phase 3 clinical trials for treating POMC or LEPR heterozygous deficiency obesities, steroid receptor coactivator 1 deficiency obesity, SH2B1 deficiency obesity, MC4 receptor deficiency obesity, and other MC4R disorders. The company has licensing agreements with LG Chem, Ltd; Ipsen Pharma S.A.S; Camurus; RareStone Group Ltd.; and LG Chem, Ltd. The company was formerly known as Rhythm Metabolic, Inc. and changed its name to Rhythm Pharmaceuticals, Inc. in October 2015. Rhythm Pharmaceuticals, Inc. was founded in 2008 and is headquartered in Boston, Massachusetts.Travere Therapeutics NASDAQ:TVTX$17.92 +0.13 (+0.73%) Closing price 04:00 PM EasternExtended Trading$18.15 +0.23 (+1.28%) As of 04:33 PM Eastern Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.Travere Therapeutics, Inc., a biopharmaceutical company, identifies, develops, and delivers therapies to people living with rare kidney and metabolic diseases. Its products include FILSPARI (sparsentan), a once-daily, oral medication designed to target two critical pathways in the disease progression of IgA Nephropathy (endothelin 1 and angiotensin-II); and Thiola and Thiola EC (tiopronin tablets) for the treatment of cystinuria, a rare genetic cystine transport disorder that causes high cystine levels in the urine and the formation of recurring kidney stones. The company's clinical-stage programs consist of Sparsentan, a novel investigational product candidate, which has been granted Orphan Drug Designation for the treatment of focal segmental glomerulosclerosis in the U.S. and Europe; and Pegtibatinase (TVT-058), a novel investigational human enzyme replacement candidate being evaluated for the treatment of classical homocystinuria. It has a cooperative research and development agreement with National Institutes of Health's National Center for Advancing Translational Sciences and Alagille Syndrome Alliance for the identification of potential small molecule therapeutics for Alagille syndrome. The company was formerly known as Retrophin, Inc. and changed its name to Travere Therapeutics, Inc. in November 2020. Travere Therapeutics, Inc. was incorporated in 2008 and is headquartered in San Diego, California. 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