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CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Merck KGaA stock logo
MKKGY
Merck KGaA
$25.77
+1.7%
$25.80
$24.32
$37.92
$16.65B0.9150,382 shs72,392 shs
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
$12.22
$11.08
$9.20
$16.05
$5.74B0.19121 shsN/A
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
$8.99
+3.0%
$8.65
$6.53
$9.14
$15.30B0.274,066 shs84,376 shs
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
$25.98
+9.2%
$25.85
$11.88
$36.91
$19.30B-1.023.07 million shs3.40 million shs
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Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Merck KGaA stock logo
MKKGY
Merck KGaA
+1.66%+1.38%+4.38%-1.98%-32.49%
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
0.00%0.00%+10.09%+16.83%-8.54%
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
+2.98%+4.41%+1.35%+7.02%-21.36%
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
+9.16%+9.62%-8.91%+26.18%+116.50%
CompanyCurrent Price50-Day Moving Average52-Week RangeMarket CapBetaAvg. VolumeToday's Volume
Merck KGaA stock logo
MKKGY
Merck KGaA
$25.77
+1.7%
$25.80
$24.32
$37.92
$16.65B0.9150,382 shs72,392 shs
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
$12.22
$11.08
$9.20
$16.05
$5.74B0.19121 shsN/A
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
$8.99
+3.0%
$8.65
$6.53
$9.14
$15.30B0.274,066 shs84,376 shs
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
$25.98
+9.2%
$25.85
$11.88
$36.91
$19.30B-1.023.07 million shs3.40 million shs
A Guide To High-Short-Interest Stocks Cover

MarketBeat's analysts have just released their top five short plays for September 2025. Learn which stocks have the most short interest and how to trade them. Enter your email address to see which companies made the list.

Get This Free Report

Compare Price Performance

Company1-Day Performance7-Day Performance30-Day Performance90-Day Performance1-Year Performance
Merck KGaA stock logo
MKKGY
Merck KGaA
+1.66%+1.38%+4.38%-1.98%-32.49%
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
0.00%0.00%+10.09%+16.83%-8.54%
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
+2.98%+4.41%+1.35%+7.02%-21.36%
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
+9.16%+9.62%-8.91%+26.18%+116.50%
CompanyConsensus Rating ScoreConsensus RatingConsensus Price Target% Upside from Current Price
Merck KGaA stock logo
MKKGY
Merck KGaA
2.33
HoldN/AN/A
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
0.00
N/AN/AN/A
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
0.00
N/AN/AN/A
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
2.65
Moderate Buy$33.7930.05% Upside

Current Analyst Ratings Breakdown

Latest OPHLF, SMMT, MKKGY, and SGIOY Analyst Ratings

DateCompanyBrokerageActionRatingPrice TargetDetails
9/3/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
Guggenheim
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Initiated CoverageBuy$40.00
9/3/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
JMP Securities
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingMarket Outperform$40.00
9/2/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingBuy$50.00
8/27/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetBuy$44.00 ➝ $50.00
8/19/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
Summit Redstone
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Set Price Target$21.00
8/19/2025
Merck KGaA stock logo
MKKGY
Merck KGaA
Barclays
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DowngradeStrong-BuyHold
8/19/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
JMP Securities
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Reiterated RatingMarket Outperform$40.00
8/18/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
Piper Sandler
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Initiated CoverageNeutral$21.00
8/15/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
HC Wainwright
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Reiterated RatingBuy$44.00
8/14/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
Zacks Research
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DowngradeHoldStrong Sell
8/12/2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
Evercore ISI
Subscribe to MarketBeat All Access for the firm's recommendation accuracy rating
Boost Price TargetOutperform$30.00 ➝ $34.00
(Data available from 9/6/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)
CompanyAnnual RevenuePrice/SalesCashflowPrice/CashBook ValuePrice/Book
Merck KGaA stock logo
MKKGY
Merck KGaA
$22.57B0.74$8.16 per share3.16$50.22 per share0.51
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
$3.20B1.80$1.08 per share11.34$11.07 per share1.10
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
$2.88B5.31$0.74 per share12.16$5.29 per share1.70
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
$700K27,570.35N/AN/A$0.53 per share49.02
CompanyNet IncomeEPSTrailing P/E RatioForward P/E RatioP/E GrowthNet MarginsReturn on Equity (ROE)Return on Assets (ROA)Next Earnings Date
Merck KGaA stock logo
MKKGY
Merck KGaA
$3.00B$2.3810.8312.573.1713.49%9.78%5.75%11/13/2025 (Estimated)
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
$330.31M$0.6219.71N/A8.75%5.47%4.12%10/30/2025 (Estimated)
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
$1.12BN/A15.3213.832.04N/AN/AN/A10/27/2025 (Estimated)
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
-$221.32M-$1.01N/AN/AN/AN/A-208.64%-181.28%10/29/2025 (Estimated)

Latest OPHLF, SMMT, MKKGY, and SGIOY Earnings

DateQuarterCompanyConsensus EstimateReported EPSBeat/MissGap EPSRevenue EstimateActual RevenueDetails
8/11/2025Q2 2025
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
-$0.10-$0.76-$0.66-$0.76N/AN/A
8/7/2025Q2 2025
Merck KGaA stock logo
MKKGY
Merck KGaA
$0.51$0.57+$0.06$0.57$5.34 billion$6.11 billion
8/4/2025Q1 2026
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
$0.3432$0.2614-$0.0818$0.26$827.29 million$886.27 million
7/28/2025Q1 2026
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
$0.1401$0.16+$0.0199$0.16$719.55 million$672.90 million
CompanyAnnual PayoutDividend Yield3-Year Dividend GrowthPayout RatioYears of Consecutive Growth
Merck KGaA stock logo
MKKGY
Merck KGaA
$0.331.28%N/A13.87%N/A
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
N/AN/AN/AN/AN/A
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
$0.151.67%N/AN/AN/A
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
N/AN/AN/AN/AN/A
CompanyDebt-to-Equity RatioCurrent RatioQuick Ratio
Merck KGaA stock logo
MKKGY
Merck KGaA
0.22
1.24
0.78
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
0.13
2.99
2.56
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
0.01
6.63
6.13
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
N/A
5.13
5.13
CompanyEmployeesShares OutstandingFree FloatOptionable
Merck KGaA stock logo
MKKGY
Merck KGaA
62,557646.21 millionN/ANot Optionable
Ono Pharmaceutical Co. stock logo
OPHLF
Ono Pharmaceutical
3,853469.71 millionN/ANot Optionable
Shionogi & Co., Ltd. Unsponsored ADR stock logo
SGIOY
Shionogi & Co., Ltd. Unsponsored ADR
4,9591.70 billionN/ANot Optionable
Summit Therapeutics PLC stock logo
SMMT
Summit Therapeutics
110742.85 million112.17 millionOptionable

Recent News About These Companies

HC Wainwright Reaffirms Buy Rating for Summit Therapeutics (NASDAQ:SMMT)
Summit Therapeutics to Host Update Call at WCLC 2025 on September 8, 2025
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New MarketBeat Followers Over Time

Media Sentiment Over Time

Merck KGaA stock logo

Merck KGaA OTCMKTS:MKKGY

$25.77 +0.42 (+1.66%)
As of 09/5/2025 03:59 PM Eastern

Merck KGaA operates as a science and technology company in Germany. It operates through Life Science, Healthcare, and Electronics segments. The company's Life Science segment offers tools, chemicals, and equipment for academic labs, biotech, and pharmaceutical manufacturers, as well as industrial sector. This segment provides drug manufacturers with process development expertise and technologies, such as continuous bioprocessing; testing kits and services; reagents and services; testing solutions that analyze air, water, and soil; and testing and tools, as well as products that help test nutritional value and identify quality inconsistencies. Its Healthcare segment discovers, develops, manufacturers, and markets prescription drugs and biopharmaceuticals for the treatment of oncology, neurology and immunology, fertility, endocrinology, as well as cardiovascular, diabetes, thyroid disorders, and multiple sclerosis; general medicines; and injection device and disease monitoring software. The Electronics segment supplies materials for the semiconductor and display industries and surface design, such as delivery systems and services, as well as surface solutions, including cosmetics, effect pigments, and functional solutions. In addition, it has in-licensing agreement with Debiopharm International SA for developing and commercializing drug candidates for the treatment of head and neck cancer; Jiangsu Hengrui Pharmaceuticals Co. Ltd. for developing, manufacturing, and commercializing drug candidates for the treatment of metastatic colorectal cancer; and Abbisko Therapeutics Co. Ltd. for developing and commercializing of drug candidates for the treatment of tenosynovial giant cell tumor, as well as license and collaboration agreement with Merck KGaA to discover two targeted protein degraders against critical oncogenic proteins. The company was founded in 1668 and is headquartered in Darmstadt, Germany. Merck KGaA operates as a subsidiary of E. Merck KGaA.

Ono Pharmaceutical stock logo

Ono Pharmaceutical OTCMKTS:OPHLF

$12.22 0.00 (0.00%)
As of 09/5/2025

Ono Pharmaceutical Co., Ltd., together with its subsidiaries, produces, purchases, and sells pharmaceuticals and diagnostic reagents worldwide. It offers Opdivo Intravenous Infusion and Kyprolis Intravenous Injection for malignant tumors; Emend capsules/Proemend intravenous injections for chemotherapy-induced nausea and vomiting; Demser capsules for the symptoms in patients with pheochromocytoma; and Mektovi, Velexbru, and Braftovi capsules for malignant tumors, as well as ADLUMIZ tablets for cancer cachexia. The company also provides Glactiv tablets for type 2 diabetes; Forxiga tablets for diabetes; Onoact Intravenous Infusion for tachyarrhythmia; Opalmon tablets to treat peripheral circulatory disorder; Coralan for chronic heart failure; Orencia injections for rheumatoid arthritis; Rivastach patches for Alzheimer's disease; Ongentys tablets for Parkinson's disease; Parsabiv, an intravenous infusion for dialysis patients; Staybla tablets for overactive bladder; Onon capsules and Dry Syrups for bronchial asthma and allergic rhinitis; and JOYCLU intra-articular injection for the improvement of joint function, as well as Recalbon tablets for osteoporosis. In addition, it develops products for hepatocellular and urothelial carcinoma; ovarian, bladder, prostate, pancreatic, gastric, esophageal, colorectal, thyroid, cell lung, and breast cancer; acute myeloid leukemia; solid tumors; myelodysplastic syndrome; melanoma; T-cell lymphoma; tachyarrhythmia; pemphigus; scleroderma; seizures; diabetic polyneuropathy; neurodegenerative diseases; autoimmune diseases; narcolepsy; and thrombosis. The company has a collaboration with Adimab, LLC to discover novel antibody drugs; a research collaboration with Turbine Ltd. to identify and validate novel oncology targets; Harvard University for validating novel therapeutic targets; and a strategic drug discovery collaboration with Sibylla Biotech in central nervous system disorders. The company was founded in 1717 and is headquartered in Osaka, Japan.

Shionogi & Co., Ltd. Unsponsored ADR stock logo

Shionogi & Co., Ltd. Unsponsored ADR OTCMKTS:SGIOY

$8.99 +0.26 (+2.98%)
As of 09/5/2025 03:57 PM Eastern

Shionogi & Co., Ltd. engages in the research, development, manufacture, and distribution of pharmaceuticals, diagnostic reagents, and medical devices in Japan. It offers Fetroja, a multidrug-resistant for gram-negative bacterial infection treatment; Cabenuva and Apretude an anti-HIV and HIV prophylactic drug; Xocova an oral COVID-19 treatment drug; Finibax a carbapenem antibiotic; Xofluza, an influenza antiviral drug; and Tivicay, an anti-HIV drug. It also develops S-872600 an influenza nasal vaccine; S-875670 anCOVID-19 nasal vaccine; S-540956 a nucleic acid adjuvant; S-554110 a nontuberculous mycobacterial infection; S-337395 for RSV infections; S-892216 for COVID-19 therapeutics; Olorofim for invasive aspergillosis; cefiderocol for aerobic gram-negative bacterial infections and infectious diseases; S-268019 a COVID-19 prophylactic vaccine; S-268019 a prophylactic vaccine for COVID-19; ensitrelvir for COVID-19 treatment and prevention; baloxavir for influenza virus infection; S-365598 for HIV infection; and S-555739 for suppressing aggravation of COVID-19. In addition, the company develops S-540956 for nucleic acid adjuvant; S-109802 for post-stroke spasticity; S-151128 for chronic pain; S-588210 and S-531011 for solid tumor; S-309309 for obesity; BPN14770 for Alzheimer's disease and fragile X syndrome; S-588410 for bladder cancer; S-488210 for head and neck squamous cell carcinoma; S-005151 for Acute ischemic stroke and epidermolysis bullosa; Rizmoic for opioid-induced constipation; ADR-001 for decompensated liver cirrhosis; S-222611 for malignant tumor; S-812217 for depression; GRT7039 for pain associated with osteoarthritis of the knee; SDT-001 for inattentive ADHD; S-588410 for esophageal cancer; SR-0379 for cutaneous ulcer; and S-723595 for type 2 diabetes. The company was formerly known as Shionogi Shoten Co., Ltd. and changed its name to Shionogi & Co., Ltd. in 1943. Shionogi & Co., Ltd. was founded in 1878 and is headquartered in Osaka, Japan.

Summit Therapeutics stock logo

Summit Therapeutics NASDAQ:SMMT

$25.98 +2.18 (+9.16%)
Closing price 09/5/2025 04:00 PM Eastern
Extended Trading
$25.93 -0.05 (-0.19%)
As of 09/5/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Summit Therapeutics Inc., a biopharmaceutical company, focuses on discovery, development, and commercialization of patient, physician, caregiver, and societal friendly medicinal therapies in the United States, and the United Kingdom. The company's lead development candidate is Ivonescimab, a bispecific antibody for immunotherapy through blockade of PD-1 with the anti-angiogenesis; and anti-infectives portfolio includes SMT-738, a novel class of precision antibiotics for the treatment of multidrug resistant infections, which primarily includes carbapenem-resistant Enterobacteriaceae infections. It has a collaboration and license agreement with Akeso, Inc. and its affiliates to develop and commercialize ivonescimab, as well as strategic collaboration with The University of Texas MD Anderson Cancer Center for the purpose of accelerating the development of ivonescimab. The company was founded in 2003 and is headquartered in Miami, Florida.