Castle Biosciences, Inc. (NASDAQ:CSTL - Free Report) - Leerink Partnrs issued their Q1 2026 earnings per share (EPS) estimates for shares of Castle Biosciences in a research note issued to investors on Friday, February 28th. Leerink Partnrs analyst P. Souda forecasts that the company will post earnings per share of ($0.57) for the quarter. The consensus estimate for Castle Biosciences' current full-year earnings is $0.44 per share. Leerink Partnrs also issued estimates for Castle Biosciences' Q2 2026 earnings at ($0.56) EPS, Q3 2026 earnings at ($0.43) EPS, Q4 2026 earnings at ($0.36) EPS and FY2027 earnings at ($1.32) EPS.
CSTL has been the topic of several other research reports. Stephens reaffirmed an "overweight" rating and issued a $41.00 target price on shares of Castle Biosciences in a report on Thursday, January 2nd. Scotiabank raised their target price on shares of Castle Biosciences from $37.00 to $44.00 and gave the company a "sector outperform" rating in a research note on Wednesday, November 6th. Finally, Robert W. Baird upped their target price on shares of Castle Biosciences from $36.00 to $37.00 and gave the company an "outperform" rating in a research report on Friday, February 28th. Seven investment analysts have rated the stock with a buy rating, Based on data from MarketBeat.com, the stock has a consensus rating of "Buy" and an average target price of $40.00.
View Our Latest Stock Analysis on CSTL
Castle Biosciences Price Performance
Shares of CSTL traded down $0.48 during mid-day trading on Monday, reaching $20.84. The company had a trading volume of 170,286 shares, compared to its average volume of 455,671. The company's 50-day moving average is $26.87 and its 200-day moving average is $29.05. Castle Biosciences has a twelve month low of $16.97 and a twelve month high of $35.84. The company has a market capitalization of $583.75 million, a P/E ratio of 104.98 and a beta of 0.98. The company has a debt-to-equity ratio of 0.02, a current ratio of 7.78 and a quick ratio of 7.64.
Insider Activity
In other news, Director Daniel Bradbury sold 7,867 shares of the company's stock in a transaction dated Wednesday, February 5th. The stock was sold at an average price of $28.17, for a total transaction of $221,613.39. The transaction was disclosed in a legal filing with the Securities & Exchange Commission, which is available through this link. Also, insider Derek J. Maetzold sold 9,364 shares of Castle Biosciences stock in a transaction that occurred on Tuesday, December 17th. The shares were sold at an average price of $28.34, for a total value of $265,375.76. Following the completion of the sale, the insider now directly owns 84,762 shares in the company, valued at approximately $2,402,155.08. This represents a 9.95 % decrease in their position. The disclosure for this sale can be found here. Insiders have sold 28,799 shares of company stock worth $824,289 in the last 90 days. Corporate insiders own 7.20% of the company's stock.
Hedge Funds Weigh In On Castle Biosciences
A number of large investors have recently bought and sold shares of CSTL. Wellington Management Group LLP bought a new stake in shares of Castle Biosciences in the fourth quarter worth $19,244,000. Point72 Asset Management L.P. increased its stake in Castle Biosciences by 828.3% in the 3rd quarter. Point72 Asset Management L.P. now owns 499,192 shares of the company's stock valued at $14,237,000 after buying an additional 445,415 shares during the last quarter. Millennium Management LLC lifted its position in Castle Biosciences by 290.5% during the 4th quarter. Millennium Management LLC now owns 548,809 shares of the company's stock worth $14,626,000 after buying an additional 408,272 shares in the last quarter. BNP Paribas Financial Markets acquired a new position in shares of Castle Biosciences during the 4th quarter worth about $6,639,000. Finally, Captrust Financial Advisors grew its holdings in shares of Castle Biosciences by 2,567.5% in the 4th quarter. Captrust Financial Advisors now owns 215,322 shares of the company's stock valued at $5,738,000 after acquiring an additional 207,250 shares in the last quarter. Institutional investors and hedge funds own 92.60% of the company's stock.
About Castle Biosciences
(
Get Free Report)
Castle Biosciences, Inc, a molecular diagnostics company, provides testing solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus, uveal melanoma, and mental health conditions. It offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test to identify the risk of metastasis for patients diagnosed with invasive cutaneous melanoma; DecisionDx-SCC, a proprietary risk stratification GEP test for patients with cutaneous squamous cell carcinoma; MyPath Melanoma, a test used for patients with difficult-to-diagnose melanocytic lesions; and TissueCypher, a spatial omics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, or low-grade dysplasia Barrett's esophagus.
Featured Articles

Before you consider Castle Biosciences, you'll want to hear this.
MarketBeat keeps track of Wall Street's top-rated and best performing research analysts and the stocks they recommend to their clients on a daily basis. MarketBeat has identified the five stocks that top analysts are quietly whispering to their clients to buy now before the broader market catches on... and Castle Biosciences wasn't on the list.
While Castle Biosciences currently has a Buy rating among analysts, top-rated analysts believe these five stocks are better buys.
View The Five Stocks Here
Which stocks are likely to thrive in today's challenging market? Enter your email address and we'll send you MarketBeat's list of ten stocks that will drive in any economic environment.
Get This Free Report
Like this article? Share it with a colleague.
Link copied to clipboard.