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Best Penny Stocks Under 50 Cents Right Now

It can be difficult to find a deal in the stock market regardless of current market conditions. For the last decade, stocks have traded well above historical average P/E ratios. Fortunately there are still a handful of undervalued stocks in corners of the market that most investors ignore. These penny stocks all have a super-low share price of $0.50 or less and are sorted by average trading volume in dollars. These companies are considered the most actively-traded stocks priced under $0.50.

Carisma Therapeutics stock logo

1. Carisma Therapeutics NASDAQ:CARM

$0.37 0.00 (-0.77%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.38 +0.00 (+0.24%)
As of 09/12/2025 07:57 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Carisma Therapeutics, Inc, a clinical-stage cell therapy company, focuses on discovering and developing immunotherapies to treat cancer and other serious diseases in the United States. More about Carisma Therapeutics

Market Capitalization
$15.75 million
P/E Ratio
-0.24
Consensus Rating
Moderate Buy
Consensus Price Target
$1.93 (+414.6% Upside)
Volume
793,328 shares
Average Volume
25.68 million shares
ModivCare stock logo

2. ModivCare NASDAQ:MODV

$0.44 -0.14 (-23.65%)
Closing price 08/27/2025
Extended Trading
$0.44 0.00 (0.00%)
As of 08/27/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

ModivCare Inc, a technology-enabled healthcare services company, provides a suite of integrated supportive care solutions for public and private payors and their members. More about ModivCare

Market Capitalization
$6.33 million
P/E Ratio
-0.03
Consensus Rating
Hold
Consensus Price Target
$8.38 (+1,799.1% Upside)
Volume
18.49 million shares
Average Volume
19.51 million shares
Dragonfly Energy stock logo

3. Dragonfly Energy NASDAQ:DFLI

$0.27 -0.02 (-5.67%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.28 +0.01 (+2.37%)
As of 09/12/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Dragonfly Energy Holdings Corp. engages in the manufacturing and sale of deep cycle lithium-ion batteries for recreational vehicles, marine vessels, solar and off-grid residence industries, and industrial and energy storage markets. More about Dragonfly Energy

Market Capitalization
$17.96 million
P/E Ratio
-0.07
Consensus Rating
Moderate Buy
Consensus Price Target
$1.50 (+446.4% Upside)
Volume
3.38 million shares
Average Volume
21.33 million shares
TPI Composites stock logo

4. TPI Composites NASDAQ:TPIC

$0.12 -0.11 (-48.51%)
Closing price 08/18/2025
Extended Trading
$0.12 0.00 (0.00%)
As of 08/18/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

TPI Composites, Inc manufactures and sells composite wind blades, and related precision molding and assembly systems to original equipment manufacturers (OEMs) in the United States, Mexico, Europe, the Middle East, Africa, and India. More about TPI Composites

Market Capitalization
$5.90 million
P/E Ratio
-0.03
Consensus Rating
Reduce
Consensus Price Target
$1.73 (+1,332.5% Upside)
Volume
69.85 million shares
Average Volume
44.66 million shares
Actelis Networks stock logo

5. Actelis Networks NASDAQ:ASNS

$0.44 -0.01 (-1.56%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.43 -0.01 (-1.29%)
As of 09/12/2025 07:52 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Actelis Networks, Inc engages in the design, development, manufacture, and marketing of cyber hardened, hybrid fiber, networking solutions for Internet of Things and telecommunication companies in North America, Europe, the Middle East, Israel, and the Asia Pacific. More about Actelis Networks

Market Capitalization
$5 million
P/E Ratio
-0.56
Consensus Rating
Buy
Consensus Price Target
$5.00 (+1,047.8% Upside)
Volume
619,186 shares
Average Volume
8.99 million shares
Senseonics stock logo

6. Senseonics NYSE:SENS

$0.46 +0.00 (+1.03%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.46 +0.00 (+0.43%)
As of 09/12/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Senseonics Holdings, Inc, a medical technology company, focuses on development and manufacturing of continuous glucose monitoring (CGM) systems for people with diabetes in the United States and internationally. More about Senseonics

Market Capitalization
$374.75 million
P/E Ratio
-3.54
Consensus Rating
Buy
Consensus Price Target
$1.54 (+234.2% Upside)
Volume
5.35 million shares
Average Volume
7.97 million shares
ESSA Pharma stock logo

7. ESSA Pharma NASDAQ:EPIX

$0.20 0.00 (-1.27%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.20 +0.00 (+0.54%)
As of 09/12/2025 07:51 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

ESSA Pharma Inc, a clinical stage pharmaceutical company, focuses the development of small molecule drugs for the treatment of prostate cancer. More about ESSA Pharma

Market Capitalization
$9.72 million
P/E Ratio
-0.36
Consensus Rating
Hold
Consensus Price Target
$2.00 (+885.7% Upside)
Volume
1.70 million shares
Average Volume
18.05 million shares
Adaptimmune Therapeutics stock logo

8. Adaptimmune Therapeutics NASDAQ:ADAP

$0.06 +0.01 (+10.89%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.06 +0.00 (+8.75%)
As of 09/12/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Adaptimmune Therapeutics plc, a clinical-stage biopharmaceutical company, provides novel cell therapies primarily to cancer patients in the United States and the United Kingdom. More about Adaptimmune Therapeutics

Market Capitalization
$13.39 million
P/E Ratio
-0.09
Consensus Rating
Hold
Consensus Price Target
$1.35 (+2,313.7% Upside)
Volume
63.42 million shares
Average Volume
59.08 million shares
Plus Therapeutics stock logo

9. Plus Therapeutics NASDAQ:PSTV

$0.45 -0.02 (-4.81%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.45 0.00 (-0.07%)
As of 09/12/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Plus Therapeutics, Inc, a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer. More about Plus Therapeutics

Market Capitalization
$46.65 million
P/E Ratio
-0.20
Consensus Rating
Buy
Consensus Price Target
$7.88 (+1,660.6% Upside)
Volume
5.04 million shares
Average Volume
6.27 million shares
Biodesix stock logo

10. Biodesix NASDAQ:BDSX

$0.38 -0.04 (-9.18%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.37 -0.01 (-1.89%)
As of 09/12/2025 07:44 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Biodesix, Inc operates as a data-driven diagnostic solutions company in the United States. The company offers blood-based lung tests, including Nodify XL2 and Nodify CDT tests, together marketed as part of Nodify Lung Nodule Risk Assessment testing strategy, to assess the risk of lung cancer and help in identifying the appropriate treatment pathway and help physicians in reclassifying risk of malignancy in patients with suspicious lung nodules. More about Biodesix

Market Capitalization
$60.56 million
P/E Ratio
-1.29
Consensus Rating
Moderate Buy
Consensus Price Target
$1.75 (+366.5% Upside)
Volume
3.52 million shares
Average Volume
5.81 million shares
Datavault AI stock logo

11. Datavault AI NASDAQ:DVLT

$0.33 -0.02 (-4.40%)
As of 09/12/2025 04:00 PM Eastern

Datavault AI Inc, a data sciences technology company, owns and operates data management and supercomputer platforms. It offers data technology and software solutions. More about Datavault AI

Market Capitalization
$34.36 million
Consensus Rating
Strong Buy
Consensus Price Target
$7.00 (+2,003.4% Upside)
Volume
4.51 million shares
Average Volume
6.35 million shares
Today's Range
$0.33
$0.36
Co-Diagnostics stock logo

12. Co-Diagnostics NASDAQ:CODX

$0.34 0.00 (-0.84%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.35 +0.01 (+2.90%)
As of 09/12/2025 07:52 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Co-Diagnostics, Inc, a molecular diagnostics company, develops, manufactures, and sells reagents used for diagnostic tests that function through the detection and/or analysis of nucleic acid molecules in the United States and internationally. More about Co-Diagnostics

Market Capitalization
$13.25 million
P/E Ratio
-0.30
Consensus Rating
Buy
Consensus Price Target
$5.50 (+1,512.4% Upside)
Volume
599,700 shares
Average Volume
5.11 million shares
Ryvyl stock logo

13. Ryvyl NASDAQ:RVYL

$0.30 +0.00 (+0.60%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.30 0.00 (0.00%)
As of 09/12/2025 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Ryvyl Inc, a technology company, engages in the development, marketing, and sale of blockchain-based payment solutions in North America, Europe, and Asia. More about Ryvyl

Market Capitalization
$9.47 million
P/E Ratio
-0.04
Consensus Rating
Hold
Volume
1.05 million shares
Average Volume
5.52 million shares
Today's Range
$0.29
$0.31
Moleculin Biotech stock logo

14. Moleculin Biotech NASDAQ:MBRX

$0.36 -0.01 (-3.24%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.38 +0.01 (+3.08%)
As of 09/12/2025 07:53 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Moleculin Biotech, Inc, a clinical stage pharmaceutical company, focuses on the development of drug candidates for the treatment of cancers and viruses. More about Moleculin Biotech

Market Capitalization
$13.81 million
Consensus Rating
Buy
Consensus Price Target
$4.00 (+999.5% Upside)
Volume
2.53 million shares
Average Volume
4.61 million shares
Today's Range
$0.36
$0.38
Promis Neurosciences stock logo

15. Promis Neurosciences NASDAQ:PMN

$0.44 +0.02 (+5.24%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.42 -0.02 (-4.30%)
As of 09/12/2025 07:20 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

ProMIS Neurosciences, Inc discovers and develops antibody therapies and therapeutic vaccines neurodegenerative diseases and other misfolded protein diseases in Canada. More about Promis Neurosciences

Market Capitalization
$21.66 million
P/E Ratio
-2.09
Consensus Rating
Buy
Consensus Price Target
$4.33 (+885.1% Upside)
Volume
531,191 shares
Average Volume
3.11 million shares
Vaxart stock logo

16. Vaxart NASDAQ:VXRT

$0.39 +0.00 (+0.03%)
As of 09/12/2025 03:59 PM Eastern

Vaxart, Inc, a clinical-stage biotechnology company, discovers and develops oral recombinant protein vaccines based on its proprietary oral vaccine platform. More about Vaxart

Market Capitalization
$89.29 million
P/E Ratio
-1.44
Consensus Rating
Buy
Consensus Price Target
$2.00 (+412.8% Upside)
Volume
356,325 shares
Average Volume
2.79 million shares
Femasys stock logo

17. Femasys NASDAQ:FEMY

$0.39 +0.03 (+6.84%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.39 0.00 (-0.54%)
As of 09/12/2025 07:32 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Femasys Inc, a biomedical company, develops therapeutic and diagnostic solutions to address unmet women healthcare needs worldwide. More about Femasys

Market Capitalization
$11.95 million
P/E Ratio
-0.46
Consensus Rating
Buy
Consensus Price Target
$7.33 (+1,770.3% Upside)
Volume
1.22 million shares
Average Volume
2.77 million shares
Reviva Pharmaceuticals stock logo

18. Reviva Pharmaceuticals NASDAQ:RVPH

$0.44 0.00 (-0.18%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.44 0.00 (-0.07%)
As of 09/12/2025 06:55 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Reviva Pharmaceuticals Holdings, Inc, a biopharmaceutical company, discovers, develops, and commercializes next-generation therapeutics for diseases targeting unmet medical needs in the areas of central nervous system, respiratory, inflammatory, and cardiometabolic diseases. More about Reviva Pharmaceuticals

Market Capitalization
$30.13 million
P/E Ratio
-0.68
Consensus Rating
Buy
Consensus Price Target
$5.20 (+1,075.7% Upside)
Volume
785,993 shares
Average Volume
1.99 million shares
Leap Therapeutics stock logo

19. Leap Therapeutics NASDAQ:LPTX

$0.30 +0.01 (+4.74%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.29 -0.01 (-3.22%)
As of 09/12/2025 07:20 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Leap Therapeutics, Inc, a biopharmaceutical company, acquires and develops antibody therapies for the treatment of cancer. More about Leap Therapeutics

Market Capitalization
$11.81 million
P/E Ratio
-0.19
Consensus Rating
Hold
Consensus Price Target
$3.38 (+1,030.3% Upside)
Volume
605,422 shares
Average Volume
1.95 million shares
VYNE Therapeutics stock logo

20. VYNE Therapeutics NASDAQ:VYNE

$0.31 -0.01 (-1.65%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.31 +0.00 (+0.81%)
As of 09/12/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

VYNE Therapeutics Inc, a clinical-stage biopharmaceutical company, focuses on developing proprietary and therapeutics for the treatment of immuno-inflammatory conditions. More about VYNE Therapeutics

Market Capitalization
$8.04 million
P/E Ratio
-0.35
Consensus Rating
Hold
Consensus Price Target
$6.25 (+1,912.9% Upside)
Volume
1.19 million shares
Average Volume
1.77 million shares

21. IGC Pharma NYSEAMERICAN:IGC

$0.41 +0.00 (+0.50%)
As of 09/12/2025 04:10 PM Eastern

IGC Pharma, Inc, a clinical stage biotechnology company, engages in developing cannabinoid-based formulations for treating diseases and conditions, including Alzheimer's disease, dysmenorrhea, premenstrual syndrome, and chronic pain. More about IGC Pharma

Market Capitalization
$36.68 million
Consensus Rating
Buy
Consensus Price Target
$4.50 (+1,008.6% Upside)
Volume
517,984 shares
Average Volume
1.33 million shares
Today's Range
$0.40
$0.42
Abpro stock logo

22. Abpro NASDAQ:ABP

$0.18 +0.02 (+9.40%)
As of 09/12/2025 04:00 PM Eastern

Abpro Holdings Inc is a biotechnology company. The company's mission is to improve the lives of mankind facing severe and life-threatening diseases with next-generation antibody therapies. More about Abpro

Market Capitalization
$13.05 million
Consensus Rating
Buy
Consensus Price Target
$4.00 (+2,145.9% Upside)
Volume
3.23 million shares
Average Volume
3.02 million shares
Today's Range
$0.16
$0.18
EON Resources stock logo

23. EON Resources NYSEAMERICAN:EONR

$0.37 +0.01 (+2.78%)
As of 09/12/2025 04:10 PM Eastern

EON Resources Inc, an independent oil and natural gas company, focuses on the acquisition, development, exploration, and production of oil and natural gas properties in the Permian Basin. More about EON Resources

Market Capitalization
$13.43 million
Consensus Rating
Buy
Consensus Price Target
$2.00 (+440.5% Upside)
Volume
1.33 million shares
Average Volume
1.38 million shares
Today's Range
$0.36
$0.39
Leslie's stock logo

24. Leslie's NASDAQ:LESL

$0.33 0.00 (-0.30%)
Closing price 09/12/2025 04:00 PM Eastern
Extended Trading
$0.34 +0.01 (+1.50%)
As of 09/12/2025 07:45 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Leslie's, Inc operates as a direct-to-consumer pool and spa care brand in the United States. The company markets and sells pool and spa supplies and related products and services. More about Leslie's

Market Capitalization
$62.18 million
P/E Ratio
-0.74
Consensus Rating
Reduce
Consensus Price Target
$1.60 (+379.0% Upside)
Volume
1.77 million shares
Average Volume
1.51 million shares
TNL Mediagene stock logo

25. TNL Mediagene NASDAQ:TNMG

$0.35 -0.02 (-5.48%)
As of 09/12/2025 03:59 PM Eastern

TNL Mediagene engages in digital advertising, integrated marketing, marketing survey, artificial intelligence technology, data analysis, content service platform, and production of audio-visual programs. More about TNL Mediagene

Market Capitalization
$9.68 million
Consensus Rating
Buy
Consensus Price Target
$3.50 (+900.0% Upside)
Volume
639,587 shares
Average Volume
1.32 million shares
Today's Range
$0.33
$0.36