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Best Penny Stocks Under 50 Cents Right Now

It can be difficult to find a deal in the stock market regardless of current market conditions. For the last decade, stocks have traded well above historical average P/E ratios. Fortunately there are still a handful of undervalued stocks in corners of the market that most investors ignore. These penny stocks all have a super-low share price of $0.50 or less and are sorted by average trading volume in dollars. These companies are considered the most actively-traded stocks priced under $0.50.

Tilray Brands stock logo

1. Tilray Brands NASDAQ:TLRY

$0.40 -0.01 (-2.84%)
Closing price 04:00 PM Eastern
Extended Trading
$0.40 +0.00 (+0.32%)
As of 08:00 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Tilray, Inc engages in the research, cultivation, processing, and distribution of medical cannabis. The company offers its products in Argentina, Australia, Canada, Chile, Croatia, Cyprus, the Czech Republic, Germany, New Zealand, and South Africa. More about Tilray Brands

Market Capitalization
$415.08 million
P/E Ratio
-0.38
Consensus Rating
Hold
Consensus Price Target
$1.92 (+378.3% Upside)
Volume
12.80 million shares
Average Volume
29.65 million shares
Wolfspeed stock logo

2. Wolfspeed NYSE:WOLF

$0.40 -0.09 (-17.81%)
Closing price 03:59 PM Eastern
Extended Trading
$0.41 +0.01 (+2.50%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Wolfspeed, Inc operates as a powerhouse semiconductor company focuses on silicon carbide and gallium nitride (GaN) technologies in Europe, Hong Kong, China, rest of Asia-Pacific, the United States, and internationally. More about Wolfspeed

Market Capitalization
$75.74 million
P/E Ratio
-0.05
Consensus Rating
Hold
Consensus Price Target
$11.15 (+2,688.5% Upside)
Volume
80.29 million shares
Average Volume
19.51 million shares
EON Resources stock logo

3. EON Resources NYSEAMERICAN:EONR

$0.34 -0.04 (-10.94%)
As of 04:10 PM Eastern

EON Resources Inc, an independent oil and natural gas company, focuses on the acquisition, development, exploration, and production of oil and natural gas properties in the Permian Basin. More about EON Resources

Market Capitalization
$7.66 million
Consensus Rating
Buy
Consensus Price Target
$2.00 (+479.7% Upside)
Volume
2.90 million shares
Average Volume
15.14 million shares
Today's Range
$0.34
$0.39
Senseonics stock logo

4. Senseonics NYSE:SENS

$0.49 -0.01 (-1.18%)
Closing price 04:00 PM Eastern
Extended Trading
$0.50 +0.00 (+0.59%)
As of 07:33 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Senseonics Holdings, Inc, a medical technology company, focuses on development and manufacturing of continuous glucose monitoring (CGM) systems for people with diabetes in the United States and internationally. More about Senseonics

Market Capitalization
$323.25 million
P/E Ratio
-3.80
Consensus Rating
Strong Buy
Consensus Price Target
$1.55 (+213.7% Upside)
Volume
6.92 million shares
Average Volume
7.03 million shares
NuCana stock logo

5. NuCana NASDAQ:NCNA

$0.09 +0.00 (+4.00%)
Closing price 04:00 PM Eastern
Extended Trading
$0.07 -0.01 (-14.44%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

NuCana plc, a clinical-stage biopharmaceutical company, engages in the development of medicines to treat patients with cancer. More about NuCana

Market Capitalization
$500 thousand
P/E Ratio
-0.01
Consensus Rating
Moderate Buy
Consensus Price Target
$25.00 (+29,003.6% Upside)
Volume
48.50 million shares
Average Volume
36.29 million shares
Plus Therapeutics stock logo

6. Plus Therapeutics NASDAQ:PSTV

$0.32 -0.05 (-14.05%)
Closing price 04:00 PM Eastern
Extended Trading
$0.31 -0.01 (-2.89%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Plus Therapeutics, Inc, a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer. More about Plus Therapeutics

Market Capitalization
$18.70 million
P/E Ratio
-0.11
Consensus Rating
Moderate Buy
Consensus Price Target
$10.83 (+3,338.1% Upside)
Volume
23.76 million shares
Average Volume
9.85 million shares
WW International stock logo

7. WW International NASDAQ:WW

$0.25 -0.03 (-10.51%)
As of 05/15/2025

WW International, Inc provides weight management products and services worldwide. It offers a range of nutritional, activity, behavioral, and lifestyle tools and approaches products and services. More about WW International

Market Capitalization
$20.04 million
P/E Ratio
-0.04
Consensus Rating
Hold
Consensus Price Target
$2.25 (+801.4% Upside)
Volume
10.45 million shares
Average Volume
11.45 million shares
Leslie's stock logo

8. Leslie's NASDAQ:LESL

$0.45 -0.04 (-8.72%)
Closing price 04:00 PM Eastern
Extended Trading
$0.46 +0.01 (+2.00%)
As of 07:50 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Leslie's, Inc operates as a direct-to-consumer pool and spa care brand in the United States. The company markets and sells pool and spa supplies and related products and services. More about Leslie's

Market Capitalization
$91.41 million
P/E Ratio
-1.88
Consensus Rating
Reduce
Consensus Price Target
$2.27 (+404.4% Upside)
Volume
27.50 million shares
Average Volume
5.32 million shares
Nikola stock logo

9. Nikola NASDAQ:NKLA

$0.18 -0.07 (-28.74%)
Closing price 02/25/2025
Extended Trading
$0.18 0.00 (0.00%)
As of 02/25/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Nikola Corporation operates as a technology innovator and integrator that develops energy and transportation solutions in the United States and internationally. More about Nikola

Market Capitalization
$11.14 million
P/E Ratio
-0.01
Consensus Rating
Hold
Consensus Price Target
$6.00 (+3,178.7% Upside)
Volume
36.66 million shares
Average Volume
10.17 million shares
Sunnova Energy International stock logo

10. Sunnova Energy International NYSE:NOVA

$0.16 -0.06 (-28.25%)
Closing price 06/9/2025
Extended Trading
$0.16 0.00 (0.00%)
As of 06/9/2025 04:02 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Sunnova Energy International Inc engages in the provision of energy as a service in the United States. The company offers electricity, as well as offers operations and maintenance, monitoring, repairs and replacements, equipment upgrades, on-site power optimization, and solar energy system and energy storage system diagnostics services. More about Sunnova Energy International

Market Capitalization
$19.86 million
P/E Ratio
-0.05
Consensus Rating
Hold
Consensus Price Target
$4.36 (+2,657.7% Upside)
Volume
4.22 million shares
Average Volume
11.21 million shares
Carisma Therapeutics stock logo

11. Carisma Therapeutics NASDAQ:CARM

$0.40 -0.01 (-1.43%)
Closing price 04:00 PM Eastern
Extended Trading
$0.41 +0.01 (+2.35%)
As of 07:52 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Carisma Therapeutics, Inc, a clinical-stage cell therapy company, focuses on discovering and developing immunotherapies to treat cancer and other serious diseases in the United States. More about Carisma Therapeutics

Market Capitalization
$16.98 million
P/E Ratio
-0.26
Consensus Rating
Hold
Consensus Price Target
$1.93 (+380.5% Upside)
Volume
851,846 shares
Average Volume
3.84 million shares
Harvard Bioscience stock logo

12. Harvard Bioscience NASDAQ:HBIO

$0.46 -0.05 (-10.14%)
Closing price 04:00 PM Eastern
Extended Trading
$0.48 +0.02 (+3.26%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Harvard Bioscience, Inc develops, manufactures, and sells technologies, products, and services for life science applications in the United States and internationally. More about Harvard Bioscience

Market Capitalization
$22.63 million
P/E Ratio
-0.35
Consensus Rating
Moderate Buy
Consensus Price Target
$3.00 (+552.2% Upside)
Volume
5.18 million shares
Average Volume
3.14 million shares
Canoo stock logo

13. Canoo NASDAQ:GOEV

$0.34 -0.07 (-15.95%)
Closing price 01/28/2025
Extended Trading
$0.34 0.00 (0.00%)
As of 01/28/2025 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Canoo Inc, a mobility technology company, designs, develops, markets, and manufactures electric vehicles for consumer, commercial fleet, government, and military customers in the United States. More about Canoo

Market Capitalization
$1.67 million
P/E Ratio
0.00
Consensus Rating
Hold
Consensus Price Target
$23.50 (+6,731.4% Upside)
Volume
6.24 million shares
Average Volume
3.68 million shares
bioAffinity Technologies stock logo

14. bioAffinity Technologies NASDAQ:BIAF

$0.30 -0.06 (-17.75%)
Closing price 04:00 PM Eastern
Extended Trading
$0.29 -0.01 (-3.04%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

bioAffinity Technologies, Inc, a biotechnology company, engages in developing non-invasive diagnostic tests and targeted cancer therapeutics. More about bioAffinity Technologies

Market Capitalization
$10.24 million
P/E Ratio
-0.41
Consensus Rating
Hold
Consensus Price Target
$6.00 (+1,927.0% Upside)
Volume
7.97 million shares
Average Volume
4.10 million shares
Vaxart stock logo

15. Vaxart NASDAQ:VXRT

$0.49 -0.04 (-7.14%)
Closing price 04:00 PM Eastern
Extended Trading
$0.50 +0.00 (+0.71%)
As of 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Vaxart, Inc, a clinical-stage biotechnology company, discovers and develops oral recombinant protein vaccines based on its proprietary oral vaccine platform. More about Vaxart

Market Capitalization
$121.57 million
P/E Ratio
-1.83
Consensus Rating
Buy
Consensus Price Target
$3.00 (+506.7% Upside)
Volume
2.85 million shares
Average Volume
2.45 million shares
Abpro stock logo

16. Abpro NASDAQ:ABP

$0.21 -0.01 (-5.38%)
As of 04:00 PM Eastern

Abpro Holdings Inc is a biotechnology company. The company's mission is to improve the lives of mankind facing severe and life-threatening diseases with next-generation antibody therapies. More about Abpro

Market Capitalization
$13.56 million
Consensus Rating
Buy
Consensus Price Target
$4.00 (+1,795.7% Upside)
Volume
2.64 million shares
Average Volume
5.52 million shares
Today's Range
$0.21
$0.22
Brand Engagement Network stock logo

17. Brand Engagement Network NASDAQ:BNAI

$0.38 +0.03 (+7.19%)
Closing price 04:00 PM Eastern
Extended Trading
$0.37 0.00 (-0.87%)
As of 07:56 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Brand Engagement Network, Inc provides conversational AI assistants. The company offers security-focused, multimodal communication, and human-like assistants. More about Brand Engagement Network

Market Capitalization
$15.13 million
P/E Ratio
-0.44
Consensus Rating
Buy
Consensus Price Target
$6.00 (+1,490.2% Upside)
Volume
1.55 million shares
Average Volume
3.03 million shares
Applied Therapeutics stock logo

18. Applied Therapeutics NASDAQ:APLT

$0.32 -0.06 (-14.79%)
Closing price 04:00 PM Eastern
Extended Trading
$0.35 +0.02 (+6.86%)
As of 07:10 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Applied Therapeutics, Inc, a clinical-stage biopharmaceutical company, engages in the development of a pipeline of novel product candidates against validated molecular targets in indications of high unmet medical need in the United States. More about Applied Therapeutics

Market Capitalization
$53.80 million
P/E Ratio
-0.75
Consensus Rating
Moderate Buy
Consensus Price Target
$6.10 (+1,783.9% Upside)
Volume
13.30 million shares
Average Volume
3.46 million shares
Adial Pharmaceuticals stock logo

19. Adial Pharmaceuticals NASDAQ:ADIL

$0.34 -0.13 (-28.67%)
Closing price 04:00 PM Eastern
Extended Trading
$0.31 -0.02 (-7.19%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Adial Pharmaceuticals, Inc, a clinical-stage biopharmaceutical company, focuses on the development of therapeutics for the treatment or prevention of addiction and related disorders. More about Adial Pharmaceuticals

Market Capitalization
$4.90 million
P/E Ratio
-0.23
Consensus Rating
Strong Buy
Consensus Price Target
$8.00 (+2,287.3% Upside)
Volume
14.85 million shares
Average Volume
2.87 million shares
Heatwurx stock logo

20. Heatwurx NASDAQ:PCSA

$0.20 -0.04 (-17.63%)
Closing price 04:00 PM Eastern
Extended Trading
$0.20 +0.00 (+2.45%)
As of 07:58 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Processa Pharmaceuticals, Inc, a clinical stage biopharmaceutical company, develops chemotherapy drugs to improve the safety and efficacy of cancer treatment. More about Heatwurx

Market Capitalization
$2.83 million
P/E Ratio
-0.06
Consensus Rating
Buy
Consensus Price Target
$6.00 (+2,958.1% Upside)
Volume
8.88 million shares
Average Volume
4.84 million shares
FiscalNote stock logo

21. FiscalNote NYSE:NOTE

$0.49 -0.04 (-7.88%)
Closing price 03:59 PM Eastern
Extended Trading
$0.51 +0.02 (+3.67%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

FiscalNote Holdings, Inc operates as technology company North America, Europe, Australia, and Asia. It combines artificial intelligence technology, machine learning, and other technologies with analytics, workflow tools, and expert research. More about FiscalNote

Market Capitalization
$84.15 million
P/E Ratio
-1.48
Consensus Rating
Buy
Consensus Price Target
$2.63 (+437.4% Upside)
Volume
11.93 million shares
Average Volume
1.80 million shares
Cognition Therapeutics stock logo

22. Cognition Therapeutics NASDAQ:CGTX

$0.30 -0.02 (-7.55%)
Closing price 04:00 PM Eastern
Extended Trading
$0.31 +0.01 (+4.00%)
As of 07:59 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Cognition Therapeutics, Inc, a clinical-stage biopharmaceutical company, engages in the discovery and development of small molecule therapeutics targeting age-related degenerative diseases and disorders of the central nervous system and retina. More about Cognition Therapeutics

Market Capitalization
$20.12 million
P/E Ratio
-0.41
Consensus Rating
Buy
Consensus Price Target
$5.63 (+1,775.0% Upside)
Volume
1.24 million shares
Average Volume
2.76 million shares
Affimed stock logo

23. Affimed NASDAQ:AFMD

$0.18 -0.10 (-34.95%)
As of 05/19/2025

Affimed N.V., a clinical-stage biopharmaceutical company, focuses on discovering and developing cancer immunotherapies in the United States and Germany. More about Affimed

Market Capitalization
$2.92 million
Consensus Rating
Hold
Consensus Price Target
$3.62 (+1,895.9% Upside)
Volume
22.99 million shares
Average Volume
4.51 million shares
Today's Range
$0.17
$0.24
Nuwellis stock logo

24. Nuwellis NASDAQ:NUWE

$0.24 -0.02 (-7.87%)
Closing price 04:00 PM Eastern
Extended Trading
$0.23 -0.01 (-4.50%)
As of 07:58 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Nuwellis, Inc, a medical device company, develops, manufactures, and commercializes medical devices used in ultrafiltration therapy. More about Nuwellis

Market Capitalization
$1.13 million
P/E Ratio
-0.01
Consensus Rating
Buy
Consensus Price Target
$17.00 (+7,051.9% Upside)
Volume
2.41 million shares
Average Volume
3.44 million shares
Mersana Therapeutics stock logo

25. Mersana Therapeutics NASDAQ:MRSN

$0.29 -0.03 (-10.46%)
Closing price 04:00 PM Eastern
Extended Trading
$0.32 +0.03 (+11.00%)
As of 07:50 PM Eastern
Extended trading is trading that happens on electronic markets outside of regular trading hours. This is a fair market value extended hours price provided by Polygon.io. Learn more.

Mersana Therapeutics, Inc, a clinical stage biopharmaceutical company, develops antibody drug conjugates (ADC) for cancer patients with unmet needs. More about Mersana Therapeutics

Market Capitalization
$40.51 million
P/E Ratio
-0.49
Consensus Rating
Buy
Consensus Price Target
$5.20 (+1,686.9% Upside)
Volume
15.79 million shares
Average Volume
2.69 million shares