Apogee Therapeutics (APGE) Competitors $36.35 +0.34 (+0.93%) As of 02:48 PM Eastern This is a fair market value price provided by Polygon.io. Learn more. Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestTrendsBuy This Stock APGE vs. RYTM, RNA, NUVL, ABVX, AXSM, CRSP, MRUS, VKTX, TGTX, and ACADShould you be buying Apogee Therapeutics stock or one of its competitors? The main competitors of Apogee Therapeutics include Rhythm Pharmaceuticals (RYTM), Avidity Biosciences (RNA), Nuvalent (NUVL), Abivax (ABVX), Axsome Therapeutics (AXSM), CRISPR Therapeutics (CRSP), Merus (MRUS), Viking Therapeutics (VKTX), TG Therapeutics (TGTX), and ACADIA Pharmaceuticals (ACAD). These companies are all part of the "pharmaceutical products" industry. Apogee Therapeutics vs. Its Competitors Rhythm Pharmaceuticals Avidity Biosciences Nuvalent Abivax Axsome Therapeutics CRISPR Therapeutics Merus Viking Therapeutics TG Therapeutics ACADIA Pharmaceuticals Apogee Therapeutics (NASDAQ:APGE) and Rhythm Pharmaceuticals (NASDAQ:RYTM) are both medical companies, but which is the superior stock? We will compare the two businesses based on the strength of their analyst recommendations, institutional ownership, risk, valuation, profitability, dividends, earnings and media sentiment. Is APGE or RYTM more profitable? Apogee Therapeutics has a net margin of 0.00% compared to Rhythm Pharmaceuticals' net margin of -117.13%. Apogee Therapeutics' return on equity of -34.65% beat Rhythm Pharmaceuticals' return on equity.Company Net Margins Return on Equity Return on Assets Apogee TherapeuticsN/A -34.65% -32.76% Rhythm Pharmaceuticals -117.13%-1,831.43%-48.33% Which has more volatility & risk, APGE or RYTM? Apogee Therapeutics has a beta of 1.43, suggesting that its share price is 43% more volatile than the S&P 500. Comparatively, Rhythm Pharmaceuticals has a beta of 2.38, suggesting that its share price is 138% more volatile than the S&P 500. Do insiders and institutionals believe in APGE or RYTM? 79.0% of Apogee Therapeutics shares are owned by institutional investors. 42.8% of Apogee Therapeutics shares are owned by company insiders. Comparatively, 6.1% of Rhythm Pharmaceuticals shares are owned by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock is poised for long-term growth. Which has stronger valuation & earnings, APGE or RYTM? Apogee Therapeutics has higher earnings, but lower revenue than Rhythm Pharmaceuticals. Rhythm Pharmaceuticals is trading at a lower price-to-earnings ratio than Apogee Therapeutics, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioApogee TherapeuticsN/AN/A-$182.15M-$4.13-8.80Rhythm Pharmaceuticals$130.13M51.52-$260.60M-$3.01-33.53 Does the media refer more to APGE or RYTM? In the previous week, Rhythm Pharmaceuticals had 12 more articles in the media than Apogee Therapeutics. MarketBeat recorded 17 mentions for Rhythm Pharmaceuticals and 5 mentions for Apogee Therapeutics. Rhythm Pharmaceuticals' average media sentiment score of 0.80 beat Apogee Therapeutics' score of -0.16 indicating that Rhythm Pharmaceuticals is being referred to more favorably in the news media. Company Very Positive Positive Neutral Negative Very Negative Overall Sentiment Apogee Therapeutics 2 Very Positive mention(s) 0 Positive mention(s) 0 Neutral mention(s) 1 Negative mention(s) 0 Very Negative mention(s) Neutral Rhythm Pharmaceuticals 10 Very Positive mention(s) 1 Positive mention(s) 3 Neutral mention(s) 0 Negative mention(s) 0 Very Negative mention(s) Positive Do analysts rate APGE or RYTM? Apogee Therapeutics currently has a consensus price target of $99.00, indicating a potential upside of 172.31%. Rhythm Pharmaceuticals has a consensus price target of $101.57, indicating a potential upside of 0.64%. Given Apogee Therapeutics' higher possible upside, analysts clearly believe Apogee Therapeutics is more favorable than Rhythm Pharmaceuticals.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Apogee Therapeutics 0 Sell rating(s) 1 Hold rating(s) 6 Buy rating(s) 0 Strong Buy rating(s) 2.86Rhythm Pharmaceuticals 0 Sell rating(s) 0 Hold rating(s) 14 Buy rating(s) 1 Strong Buy rating(s) 3.07 SummaryApogee Therapeutics and Rhythm Pharmaceuticals tied by winning 8 of the 16 factors compared between the two stocks. Get Apogee Therapeutics News Delivered to You Automatically Sign up to receive the latest news and ratings for APGE and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding APGE and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart APGE vs. The Competition Export to ExcelMetricApogee TherapeuticsMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$1.67B$3.12B$5.76B$9.55BDividend YieldN/A2.23%4.53%4.07%P/E Ratio-8.7820.4630.4325.11Price / SalesN/A237.31392.2187.48Price / CashN/A42.3737.0358.50Price / Book2.717.959.016.20Net Income-$182.15M-$54.72M$3.26B$265.38M7 Day Performance-4.63%1.56%1.00%-1.25%1 Month Performance-7.04%5.71%4.19%-0.81%1 Year Performance-24.81%9.01%28.39%18.83% Apogee Therapeutics Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)APGEApogee Therapeutics3.44 of 5 stars$36.36+0.9%$99.00+172.3%-26.5%$1.67BN/A-8.7891RYTMRhythm Pharmaceuticals3.7232 of 5 stars$94.31+2.5%$101.57+7.7%+116.4%$6.11B$130.13M-31.33140News CoverageRNAAvidity Biosciences3.1499 of 5 stars$45.75-1.2%$67.00+46.4%-1.2%$5.96B$10.90M-15.25190News CoverageOptions VolumeNUVLNuvalent3.1902 of 5 stars$74.95+1.1%$119.60+59.6%-4.0%$5.32BN/A-15.3040News CoverageAnalyst ForecastInsider TradeABVXAbivax3.3596 of 5 stars$69.00-1.6%$92.33+33.8%+531.7%$5.30BN/A0.0061Short Interest ↑AXSMAxsome Therapeutics4.7817 of 5 stars$103.96-0.8%$178.00+71.2%+32.7%$5.23B$385.69M-20.50380Positive NewsCRSPCRISPR Therapeutics3.7612 of 5 stars$55.41+0.7%$71.60+29.2%+8.2%$5.00B$37.31M-10.20460MRUSMerus2.2082 of 5 stars$64.60+0.9%$88.50+37.0%+20.0%$4.84B$36.13M-11.7537News CoverageVKTXViking Therapeutics3.9747 of 5 stars$38.20+0.8%$86.92+127.6%-61.2%$4.26BN/A-24.9620Trending NewsAnalyst ForecastOptions VolumeTGTXTG Therapeutics4.3113 of 5 stars$26.39-1.2%$46.25+75.3%+14.6%$4.24B$329M71.32290Positive NewsACADACADIA Pharmaceuticals3.9104 of 5 stars$24.82+0.9%$28.88+16.3%+60.2%$4.15B$957.80M18.66510Insider Trade Related Companies and Tools Related Companies RYTM Competitors RNA Competitors NUVL Competitors ABVX Competitors AXSM Competitors CRSP Competitors MRUS Competitors VKTX Competitors TGTX Competitors ACAD Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:APGE) was last updated on 8/21/2025 by MarketBeat.com Staff From Our PartnersAlex’s “Next Magnificent Seven” stocksThe original “Magnificent Seven” turned $7K into $1.18 million. 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