DURECT (DRRX) Competitors $1.85 -0.01 (-0.54%) As of 08/5/2025 04:00 PM Eastern Add Compare Share Share Competitors Stock AnalysisAnalyst ForecastsChartCompetitorsEarningsFDA EventsHeadlinesInsider TradesOptions ChainOwnershipSEC FilingsShort InterestSustainabilityTrendsBuy This Stock DRRX vs. TKNO, ALMS, LRMR, TRDA, PRQR, FENC, DSGN, CGC, IMAB, and ACIUShould you be buying DURECT stock or one of its competitors? The main competitors of DURECT include Alpha Teknova (TKNO), Alumis (ALMS), Larimar Therapeutics (LRMR), Entrada Therapeutics (TRDA), ProQR Therapeutics (PRQR), Adherex Technologies (FENC), Design Therapeutics (DSGN), Canopy Growth (CGC), I-Mab (IMAB), and AC Immune (ACIU). These companies are all part of the "pharmaceutical products" industry. DURECT vs. Its Competitors Alpha Teknova Alumis Larimar Therapeutics Entrada Therapeutics ProQR Therapeutics Adherex Technologies Design Therapeutics Canopy Growth I-Mab AC Immune Alpha Teknova (NASDAQ:TKNO) and DURECT (NASDAQ:DRRX) are both small-cap medical companies, but which is the better business? We will compare the two companies based on the strength of their risk, valuation, institutional ownership, earnings, analyst recommendations, dividends, profitability and media sentiment. Do institutionals & insiders believe in TKNO or DRRX? 13.8% of Alpha Teknova shares are held by institutional investors. Comparatively, 28.0% of DURECT shares are held by institutional investors. 12.5% of Alpha Teknova shares are held by company insiders. Comparatively, 3.2% of DURECT shares are held by company insiders. Strong institutional ownership is an indication that endowments, hedge funds and large money managers believe a stock will outperform the market over the long term. Is TKNO or DRRX more profitable? Alpha Teknova has a net margin of -60.90% compared to DURECT's net margin of -91.54%. Alpha Teknova's return on equity of -28.48% beat DURECT's return on equity.Company Net Margins Return on Equity Return on Assets Alpha Teknova-60.90% -28.48% -19.73% DURECT -91.54%-267.36%-64.00% Do analysts recommend TKNO or DRRX? Alpha Teknova currently has a consensus target price of $10.00, indicating a potential upside of 132.56%. Given Alpha Teknova's stronger consensus rating and higher probable upside, analysts plainly believe Alpha Teknova is more favorable than DURECT.Company Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score Alpha Teknova 0 Sell rating(s) 0 Hold rating(s) 1 Buy rating(s) 1 Strong Buy rating(s) 3.50DURECT 0 Sell rating(s) 2 Hold rating(s) 0 Buy rating(s) 0 Strong Buy rating(s) 2.00 Which has more volatility and risk, TKNO or DRRX? Alpha Teknova has a beta of 0.32, meaning that its share price is 68% less volatile than the S&P 500. Comparatively, DURECT has a beta of 0.83, meaning that its share price is 17% less volatile than the S&P 500. Which has stronger valuation & earnings, TKNO or DRRX? DURECT has lower revenue, but higher earnings than Alpha Teknova. DURECT is trading at a lower price-to-earnings ratio than Alpha Teknova, indicating that it is currently the more affordable of the two stocks. CompanyGross RevenuePrice/Sales RatioNet IncomeEarnings Per SharePrice/Earnings RatioAlpha Teknova$37.74M6.09-$26.75M-$0.48-8.96DURECT$2.03M28.29-$8.32M-$0.15-12.33 Does the media favor TKNO or DRRX? In the previous week, DURECT had 2 more articles in the media than Alpha Teknova. MarketBeat recorded 2 mentions for DURECT and 0 mentions for Alpha Teknova. DURECT's average media sentiment score of 0.36 beat Alpha Teknova's score of 0.00 indicating that DURECT is being referred to more favorably in the news media. Company Overall Sentiment Alpha Teknova Neutral DURECT Neutral SummaryAlpha Teknova beats DURECT on 10 of the 17 factors compared between the two stocks. Get DURECT News Delivered to You Automatically Sign up to receive the latest news and ratings for DRRX and its competitors with MarketBeat's FREE daily newsletter. Email Address New MarketBeat Followers Over TimeWhat are MarkeBeat Followers?This chart shows the number of new MarketBeat users adding DRRX and its top 5 competitors to their watchlist. Each company is represented with a line over a 90 day period. Skip ChartMedia Sentiment Over TimeWhat is Media Sentiment?This chart shows the average media sentiment of NASDAQ and its competitors over the past 90 days as caculated by MarketBeat. The averaged score is equivalent to the following: Very Negative Sentiment <= -1.5, Negative Sentiment > -1.5 and <= -0.5, Neutral Sentiment > -0.5 and < 0.5, Positive Sentiment >= 0.5 and < 1.5, and Very Positive Sentiment >= 1.5.Skip Chart DRRX vs. The Competition Export to ExcelMetricDURECTMED IndustryMedical SectorNASDAQ ExchangeMarket Cap$57.74M$2.53B$5.59B$9.53BDividend YieldN/A1.77%4.73%4.14%P/E Ratio-12.339.1628.9123.88Price / Sales28.29717.24445.5998.82Price / CashN/A159.4135.6858.35Price / Book6.385.078.165.60Net Income-$8.32M$31.61M$3.25B$265.26M7 Day Performance-3.14%-0.38%1.17%-0.14%1 Month Performance177.49%5.79%8.27%6.08%1 Year Performance35.04%3.58%29.19%24.22% DURECT Competitors List Export to ExcelCompanyMarketRankShare PriceAnalysts' Price Target1Y Price PerformanceMarket CapRevenueP/E RatioEmployee CountIndicator(s)DRRXDURECT1.0482 of 5 stars$1.85-0.5%N/A+36.0%$57.74M$2.03M-12.3380Upcoming EarningsTKNOAlpha Teknova2.3775 of 5 stars$4.38+3.3%$10.00+128.3%+16.8%$226.59M$37.74M-9.12240Upcoming EarningsALMSAlumis2.5711 of 5 stars$4.09-1.0%$19.80+384.1%-64.6%$224.70MN/A0.00N/AUpcoming EarningsLRMRLarimar Therapeutics2.9541 of 5 stars$3.31-3.8%$18.50+458.9%-49.6%$220.26MN/A-2.2230News CoverageInsider TradeGap UpTRDAEntrada Therapeutics3.2403 of 5 stars$5.92+2.1%$25.67+333.6%-59.7%$220.13M$172.22M7.31110Positive NewsUpcoming EarningsPRQRProQR Therapeutics1.9999 of 5 stars$2.07-0.5%$8.00+286.5%+11.6%$218.84M$20.46M-5.91180FENCAdherex Technologies2.3471 of 5 stars$8.32+6.1%$13.00+56.3%+42.6%$217.43M$47.54M-16.3110News CoverageUpcoming EarningsDSGNDesign Therapeutics0.325 of 5 stars$3.96+3.7%$4.00+1.0%-12.9%$216.86MN/A-4.0040CGCCanopy Growth0.45 of 5 stars$1.10+4.8%N/A-82.2%$215.40M$225.65M-0.273,150Upcoming EarningsIMABI-Mab2.6922 of 5 stars$2.93+11.8%$6.00+104.8%+193.0%$213.53M$3.89M0.00380Gap UpACIUAC Immune2.003 of 5 stars$2.19+3.3%$12.00+447.9%-29.8%$212.87M$31.02M-3.78140News CoveragePositive NewsGap Down Related Companies and Tools Related Companies TKNO Competitors ALMS Competitors LRMR Competitors TRDA Competitors PRQR Competitors FENC Competitors DSGN Competitors CGC Competitors IMAB Competitors ACIU Competitors Top 10 Stock Comparisons Semiconductor Stocks Artificial Intelligence Stocks Growth Stocks Magnificent Seven Stocks Pharmaceutical Stocks Ecommerce Stocks Bitcoin Stocks Meme Stocks Cryptocurrency Stocks Cybersecurity Stocks This page (NASDAQ:DRRX) was last updated on 8/6/2025 by MarketBeat.com Staff From Our PartnersINVESTOR ALERT: Tiny “$3 AI Wonder Stock” on the Verge of Blasting OffRight now, we’re witnessing a monumental shift in the world.Traders Agency | SponsoredElon’s Secret Social Security BombshellTo All Americans Born Before April 16th, 1963: Did Trump Just Give The Green Light To Radically RE-DO Social S...Banyan Hill Publishing | Sponsored[Warning] Buffett Indicator hits new All-Time-HighWarren Buffett has leaned on one key indicator for decades—and it just hit an all-time high. 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