| 3/24/2025 | Wellington Management Group LLP | 122,863 | $1.04M | 0.0% | +4.2% | 0.247% | |
| 2/18/2025 | Frazier Life Sciences Management L.P. | 4,887,867 | $41.40M | 1.7% | +32.5% | 9.890% | |
| 2/17/2025 | Woodline Partners LP | 1,288,401 | $10.91M | 0.1% | +111.8% | 2.607% | |
| 2/17/2025 | Vestal Point Capital LP | 4,770,000 | $40.40M | 2.4% | +19.3% | 9.652% | |
| 2/17/2025 | Two Sigma Investments LP | 13,463 | $114K | 0.0% | -50.0% | 0.027% | |
| 2/17/2025 | Two Sigma Advisers LP | 22,822 | $193K | 0.0% | -40.4% | 0.046% | |
| 2/17/2025 | Tang Capital Management LLC | 4,893,847 | $41.45M | 2.7% | +13.2% | 9.903% | |
| 2/17/2025 | Stempoint Capital LP | 992,803 | $8.41M | 2.1% | N/A | 2.009% | |
| 2/17/2025 | Suvretta Capital Management LLC | 4,913,012 | $41.61M | 1.4% | +16.6% | 9.941% | |
| 2/17/2025 | Rafferty Asset Management LLC | 54,466 | $461K | 0.0% | +24.3% | 0.110% | |
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| 2/17/2025 | ProShare Advisors LLC | 11,906 | $101K | 0.0% | N/A | 0.024% | |
| 2/17/2025 | OCONNOR A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS LLC | 172,693 | $1.46M | 0.1% | +27.4% | 0.349% | |
| 2/17/2025 | Octagon Capital Advisors LP | 1,370,000 | $11.60M | 1.9% | N/A | 2.772% | |
| 2/17/2025 | MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 21,386 | $181K | 0.0% | -5.3% | 0.043% | |
| 2/17/2025 | Graham Capital Management L.P. | 10,479 | $89K | 0.0% | N/A | 0.021% | |
| 2/17/2025 | Deutsche Bank AG | 35,841 | $304K | 0.0% | +63.5% | 0.073% | |
| 2/17/2025 | D. E. Shaw & Co. Inc. | 73,286 | $621K | 0.0% | -18.5% | 0.148% | |
| 2/17/2025 | DAFNA Capital Management LLC | 811,678 | $6.88M | 1.7% | +12.2% | 1.642% | |
| 2/17/2025 | Bank of America Corp DE | 110,050 | $932K | 0.0% | +108.8% | 0.223% | |
| 2/17/2025 | BNP Paribas Financial Markets | 6,252 | $53K | 0.0% | -85.6% | 0.013% | |
| 2/17/2025 | Ameriprise Financial Inc. | 53,382 | $452K | 0.0% | N/A | 0.108% | |
| 2/17/2025 | Algert Global LLC | 10,360 | $88K | 0.0% | N/A | 0.021% | |
| 2/17/2025 | Allostery Investments LP | 479,100 | $4.06M | 4.2% | N/A | 0.969% | |
| 2/14/2025 | Boxer Capital Management LLC | 1,590,000 | $13.47M | 1.1% | N/A | 3.217% | |
| 2/14/2025 | Jane Street Group LLC | 69,397 | $588K | 0.0% | -86.6% | 0.140% | |
| 2/14/2025 | PDT Partners LLC | 35,201 | $298K | 0.0% | +56.8% | 0.071% | |
| 2/14/2025 | Emerald Mutual Fund Advisers Trust | 549,688 | $4.66M | 0.3% | -15.6% | 1.112% | |
| 2/14/2025 | Northern Trust Corp | 366,170 | $3.10M | 0.0% | -3.5% | 0.741% | |
| 2/14/2025 | Aquatic Capital Management LLC | 5,188 | $44K | 0.0% | N/A | 0.010% | |
| 2/14/2025 | Birchview Capital LP | 67,000 | $567K | 0.5% | -18.3% | 0.136% | |
| 2/14/2025 | Susquehanna Fundamental Investments LLC | 80,319 | $680K | 0.0% | N/A | 0.163% | |
| 2/14/2025 | Nebula Research & Development LLC | 11,579 | $98K | 0.0% | N/A | 0.023% | |
| 2/14/2025 | Adage Capital Partners GP L.L.C. | 300,000 | $2.54M | 0.0% | -78.9% | 0.607% | |
| 2/14/2025 | Syon Capital LLC | 10,993 | $93K | 0.0% | N/A | 0.022% | |
| 2/14/2025 | Silverarc Capital Management LLC | 612,173 | $5.19M | 1.1% | +6.5% | 1.239% | |
| 2/14/2025 | Tower Research Capital LLC TRC | 6,327 | $54K | 0.0% | +666.9% | 0.013% | |
| 2/14/2025 | MetLife Investment Management LLC | 19,152 | $162K | 0.0% | -14.1% | 0.039% | |
| 2/14/2025 | Dimensional Fund Advisors LP | 696,037 | $5.90M | 0.0% | +14.7% | 1.408% | |
| 2/13/2025 | Marshall Wace LLP | 117,978 | $999K | 0.0% | +691.5% | 0.239% | |
| 2/13/2025 | Walleye Capital LLC | 267,743 | $2.27M | 0.0% | N/A | 0.542% | |
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| 2/13/2025 | XTX Topco Ltd | 31,573 | $267K | 0.0% | N/A | 0.064% | |
| 2/13/2025 | Legal & General Group Plc | 8,144 | $69K | 0.0% | +22.5% | 0.016% | |
| 2/13/2025 | ADAR1 Capital Management LLC | 35,843 | $304K | 0.1% | +153.4% | 0.073% | |
| 2/13/2025 | Russell Investments Group Ltd. | 133,572 | $1.13M | 0.0% | +15.2% | 0.270% | |
| 2/13/2025 | Wells Fargo & Company MN | 20,165 | $171K | 0.0% | +29.1% | 0.041% | |
| 2/12/2025 | Martin Worley Group | 10,168 | $86K | 0.1% | N/A | 0.021% | |
| 2/12/2025 | Geode Capital Management LLC | 822,352 | $6.97M | 0.0% | -1.0% | 1.664% | |
| 2/12/2025 | Wellington Management Group LLP | 122,863 | $1.04M | 0.0% | +4.2% | 0.249% | |
| 2/12/2025 | Schroder Investment Management Group | 805,445 | $6.76M | 0.0% | +86.8% | 1.630% | |
| 2/12/2025 | JPMorgan Chase & Co. | 21,260 | $180K | 0.0% | -6.0% | 0.043% | |
| 2/11/2025 | EntryPoint Capital LLC | 11,509 | $97K | 0.0% | -52.7% | 0.023% | |
| 2/11/2025 | Corebridge Financial Inc. | 16,945 | $144K | 0.0% | -17.9% | 0.034% | |
| 2/11/2025 | Vanguard Group Inc. | 2,255,243 | $19.10M | 0.0% | +4.9% | 4.563% | |
| 2/11/2025 | American Century Companies Inc. | 10,072 | $85K | 0.0% | -71.0% | 0.020% | |
| 2/11/2025 | Intech Investment Management LLC | 17,204 | $146K | 0.0% | +58.5% | 0.035% | |
| 2/7/2025 | AlphaQuest LLC | 17,700 | $150K | 0.0% | +17.1% | 0.036% | |
| 2/6/2025 | Charles Schwab Investment Management Inc. | 100,348 | $850K | 0.0% | -9.4% | 0.203% | |
| 2/4/2025 | Bank of New York Mellon Corp | 98,547 | $835K | 0.0% | -6.7% | 0.199% | |
| 1/24/2025 | China Universal Asset Management Co. Ltd. | 10,329 | $87K | 0.0% | +24.7% | 0.021% | |
| 1/17/2025 | SG Americas Securities LLC | 14,508 | $123K | 0.0% | +10.0% | 0.029% | |
| 1/15/2025 | Hennion & Walsh Asset Management Inc. | 74,827 | $634K | 0.0% | N/A | 0.151% | |
| 12/26/2024 | JPMorgan Chase & Co. | 22,610 | $262K | 0.0% | +8.0% | 0.046% | |
| 11/19/2024 | Barclays PLC | 67,222 | $778K | 0.0% | +418.5% | 0.136% | |
| 11/16/2024 | Geode Capital Management LLC | 830,984 | $9.62M | 0.0% | +3.1% | 1.923% | |
| 11/15/2024 | Barclays PLC | 67,222 | $778K | 0.0% | +418.5% | 0.156% | |
| 11/15/2024 | Zimmer Partners LP | 95,704 | $1.11M | 0.0% | +52.6% | 0.221% | |
| 11/15/2024 | Wellington Management Group LLP | 117,923 | $1.37M | 0.0% | +40.3% | 0.273% | |
| 11/15/2024 | State Street Corp | 1,271,609 | $14.73M | 0.0% | +68.1% | 2.942% | |
| 11/15/2024 | Readystate Asset Management LP | 180,000 | $2.08M | 0.0% | N/A | 0.416% | |
| 11/15/2024 | HighVista Strategies LLC | 33,305 | $386K | 0.1% | +4.5% | 0.077% | |
| 11/15/2024 | Paloma Partners Management Co | 17,924 | $208K | 0.0% | N/A | 0.041% | |
| 11/14/2024 | PDT Partners LLC | 22,454 | $260K | 0.0% | N/A | 0.052% | |
| 11/14/2024 | Vestal Point Capital LP | 4,000,000 | $46.32M | 3.5% | +73.9% | 9.255% | |
| 11/14/2024 | Suvretta Capital Management LLC | 4,212,005 | $48.78M | 1.6% | +0.5% | 9.745% | |
| 11/13/2024 | Great Point Partners LLC | 1,299,503 | $15.05M | 4.4% | -2.9% | 3.007% | |
| 11/13/2024 | BNP Paribas Financial Markets | 43,296 | $501K | 0.0% | +1,335.5% | 0.100% | |
| 11/13/2024 | FMR LLC | 66,423 | $769K | 0.0% | +22.9% | 0.154% | |
| 11/12/2024 | Citigroup Inc. | 305,504 | $3.54M | 0.0% | +6.8% | 0.707% | |
| 11/9/2024 | Intech Investment Management LLC | 10,855 | $126K | 0.0% | N/A | 0.025% | |
| 11/8/2024 | Connor Clark & Lunn Investment Management Ltd. | 22,949 | $266K | 0.0% | +114.4% | 0.053% | |
| 11/7/2024 | First Turn Management LLC | 355,000 | $4.11M | 0.7% | -66.5% | 0.821% | |
| 11/7/2024 | Quest Partners LLC | 15,112 | $175K | 0.0% | N/A | 0.035% | |
| 10/30/2024 | Rosalind Advisors Inc. | 303,864 | $3.52M | 2.2% | -10.1% | 0.720% | |
| 10/29/2024 | Emerald Advisers LLC | 835,988 | $9.68M | 0.4% | +29.8% | 1.982% | |
| 10/29/2024 | Emerald Mutual Fund Advisers Trust | 650,980 | $7.54M | 0.4% | +23.0% | 1.543% | |
| 10/25/2024 | China Universal Asset Management Co. Ltd. | 8,286 | $96K | 0.0% | +67.1% | 0.020% | |
| 10/3/2024 | SG Americas Securities LLC | 13,189 | $153K | 0.0% | N/A | 0.031% | |
| 9/20/2024 | Healthcare of Ontario Pension Plan Trust Fund | 4,500 | $53K | 0.0% | -86.6% | 0.011% | |
| 8/16/2024 | Driehaus Capital Management LLC | 535,717 | $6.31M | 0.1% | -1.1% | 1.270% | |
| 8/15/2024 | Susquehanna Fundamental Investments LLC | 68,526 | $807K | 0.0% | +323.5% | 0.162% | |
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| 8/15/2024 | The Manufacturers Life Insurance Company | 15,437 | $182K | 0.0% | +27.3% | 0.037% | |
| 8/15/2024 | Deerfield Management Company L.P. Series C | 10,841 | $128K | 0.0% | -29.4% | 0.026% | |
| 8/14/2024 | Great Point Partners LLC | 1,338,568 | $15.77M | 3.0% | N/A | 3.173% | |
| 8/14/2024 | Marshall Wace LLP | 48,911 | $576K | 0.0% | -92.2% | 0.116% | |
| 8/14/2024 | Evoke Wealth LLC | 15,373 | $181K | 0.2% | N/A | 0.036% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 534,979 | $6.30M | 0.0% | -7.7% | 1.268% | |
| 8/8/2024 | First Turn Management LLC | 1,059,540 | $12.48M | 2.0% | -10.2% | 2.511% | |
| 8/8/2024 | Nicholas Investment Partners LP | 184,358 | $2.17M | 0.2% | +0.9% | 0.437% | |
| 8/8/2024 | American Century Companies Inc. | 28,939 | $341K | 0.0% | -11.6% | 0.069% | |
| 8/7/2024 | ClariVest Asset Management LLC | 57,096 | $673K | 0.1% | +2.8% | 0.135% | |
