| 12/13/2024 | Lord Abbett & CO. LLC | 626,905 | $20.90M | 0.1% | +35.7% | 1.605% | |
| 11/16/2024 | Geode Capital Management LLC | 746,147 | $24.87M | 0.0% | +9.3% | 1.918% | |
| 11/15/2024 | Barclays PLC | 61,806 | $2.06M | 0.0% | +167.1% | 0.158% | |
| 11/15/2024 | Jane Street Group LLC | 28,497 | $950K | 0.0% | -5.3% | 0.073% | |
| 11/15/2024 | Wellington Management Group LLP | 1,590,072 | $53.00M | 0.0% | -10.6% | 4.088% | |
| 11/15/2024 | State Street Corp | 855,814 | $28.52M | 0.0% | +6.7% | 2.200% | |
|
| 11/15/2024 | Readystate Asset Management LP | 107,345 | $3.58M | 0.1% | N/A | 0.276% | |
| 11/15/2024 | Parkman Healthcare Partners LLC | 491,272 | $16.37M | 2.1% | -29.2% | 1.263% | |
| 11/14/2024 | PFM Health Sciences LP | 113,711 | $3.79M | 0.2% | N/A | 0.292% | |
| 11/14/2024 | Verition Fund Management LLC | 8,469 | $282K | 0.0% | N/A | 0.022% | |
| 11/14/2024 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 55,079 | $1.84M | 0.0% | +10.0% | 0.142% | |
| 11/14/2024 | Ally Bridge Group NY LLC | 240,892 | $8.03M | 4.3% | +10.0% | 0.619% | |
| 11/14/2024 | Zurcher Kantonalbank Zurich Cantonalbank | 7,744 | $258K | 0.0% | +64.2% | 0.020% | |
| 11/13/2024 | Quantbot Technologies LP | 1,813 | $60K | 0.0% | -90.1% | 0.005% | |
| 11/13/2024 | FMR LLC | 4,350,099 | $144.99M | 0.0% | -1.5% | 11.183% | |
| 11/13/2024 | The Manufacturers Life Insurance Company | 113,411 | $3.78M | 0.0% | -3.7% | 0.292% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 260,721 | $8.69M | 0.0% | +197.4% | 0.670% | |
| 11/9/2024 | Intech Investment Management LLC | 8,133 | $271K | 0.0% | N/A | 0.021% | |
| 11/8/2024 | Jennison Associates LLC | 917,528 | $30.58M | 0.0% | -3.6% | 2.359% | |
| 11/7/2024 | Braun Stacey Associates Inc. | 299,156 | $9.97M | 0.4% | N/A | 0.769% | |
| 11/6/2024 | KBC Group NV | 1,954 | $65K | 0.0% | N/A | 0.005% | |
| 11/5/2024 | Victory Capital Management Inc. | 15,773 | $526K | 0.0% | N/A | 0.041% | |
| 11/2/2024 | Mesirow Financial Investment Management Inc. | 6,634 | $221K | 0.0% | N/A | 0.017% | |
| 10/29/2024 | Emerald Advisers LLC | 683,642 | $22.79M | 0.9% | +199.2% | 1.758% | |
| 10/29/2024 | Emerald Mutual Fund Advisers Trust | 419,462 | $13.98M | 0.7% | +128.5% | 1.079% | |
| 10/3/2024 | SG Americas Securities LLC | 10,514 | $350K | 0.0% | N/A | 0.027% | |
| 8/16/2024 | Driehaus Capital Management LLC | 488,793 | $13.21M | 0.1% | +25.8% | 1.257% | |
| 8/15/2024 | Lynx1 Capital Management LP | 167,317 | $4.52M | 1.6% | N/A | 0.430% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 117,739 | $3.18M | 0.0% | +40.2% | 0.303% | |
| 8/14/2024 | Squarepoint Ops LLC | 13,972 | $378K | 0.0% | +30.4% | 0.036% | |
| 8/14/2024 | Point72 Asset Management L.P. | 1,031,371 | $27.88M | 0.1% | -25.0% | 2.653% | |
| 8/14/2024 | Marshall Wace LLP | 462,623 | $12.51M | 0.0% | -18.3% | 1.190% | |
| 8/14/2024 | Integral Health Asset Management LLC | 1,100,000 | $29.73M | 2.8% | +12.8% | 2.829% | |
| 8/14/2024 | Ally Bridge Group NY LLC | 218,981 | $5.92M | 3.5% | -19.1% | 0.563% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 13,741 | $371K | 0.0% | -31.2% | 0.035% | |
| 8/8/2024 | American Century Companies Inc. | 476,390 | $12.88M | 0.0% | +70.2% | 1.225% | |
| 8/6/2024 | Emerald Advisers LLC | 228,523 | $6.18M | 0.3% | N/A | 0.588% | |
| 8/6/2024 | Emerald Mutual Fund Advisers Trust | 183,577 | $4.96M | 0.3% | N/A | 0.472% | |
| 8/6/2024 | Candriam S.C.A. | 225,917 | $6.11M | 0.0% | N/A | 0.581% | |
| 8/5/2024 | Arizona State Retirement System | 7,994 | $216K | 0.0% | N/A | 0.021% | |
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| 8/3/2024 | TD Asset Management Inc | 174,188 | $4.71M | 0.0% | +23.7% | 0.448% | |
| 8/1/2024 | Rhumbline Advisers | 42,476 | $1.15M | 0.0% | +41.7% | 0.109% | |
| 8/1/2024 | CIBC Asset Management Inc | 342,982 | $9.27M | 0.0% | +0.3% | 0.882% | |
| 7/29/2024 | Zurcher Kantonalbank Zurich Cantonalbank | 4,716 | $127K | 0.0% | N/A | 0.012% | |
| 7/26/2024 | Bank of New York Mellon Corp | 92,664 | $2.51M | 0.0% | +34.5% | 0.238% | |
| 5/24/2024 | Farallon Capital Management LLC | 2,940,500 | $63.52M | 0.3% | +88.4% | 7.563% | |
| 5/17/2024 | RA Capital Management L.P. | 3,289,119 | $71.05M | 0.9% | N/A | 8.460% | |
| 5/16/2024 | California State Teachers Retirement System | 21,747 | $470K | 0.0% | +748.2% | 0.056% | |
| 5/16/2024 | AWM Investment Company Inc. | 211,518 | $4.57M | 0.6% | N/A | 0.544% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 2,217,995 | $47.91M | 0.0% | +36.3% | 5.705% | |
| 5/14/2024 | Nan Fung Group Holdings Ltd | 118,255 | $2.55M | 2.4% | N/A | 0.304% | |
| 5/14/2024 | American International Group Inc. | 12,283 | $265K | 0.0% | +58.6% | 0.032% | |
| 5/13/2024 | Ameritas Investment Partners Inc. | 2,486 | $54K | 0.0% | +93.3% | 0.006% | |
| 5/10/2024 | Vanguard Group Inc. | 1,724,431 | $37.25M | 0.0% | +119.3% | 4.787% | |
| 5/9/2024 | Lord Abbett & CO. LLC | 475,179 | $10.26M | 0.0% | N/A | 1.319% | |
| 5/7/2024 | Sei Investments Co. | 19,861 | $429K | 0.0% | N/A | 0.055% | |
| 5/7/2024 | Swiss National Bank | 42,300 | $914K | 0.0% | N/A | 0.117% | |
| 5/7/2024 | SG Americas Securities LLC | 6,102 | $132K | 0.0% | N/A | 0.017% | |
| 5/6/2024 | Quantbot Technologies LP | 14,355 | $310K | 0.0% | N/A | 0.040% | |
| 5/2/2024 | Jennison Associates LLC | 942,404 | $20.36M | 0.0% | +96.0% | 2.616% | |
| 4/19/2024 | Denali Advisors LLC | 9,300 | $201K | 0.1% | N/A | 0.026% | |
| 2/15/2024 | Parkman Healthcare Partners LLC | 429,892 | $2.59M | 0.4% | +20.8% | 1.802% | |
| 2/14/2024 | Platinum Investment Management Ltd. | 127,048 | $766K | 0.0% | N/A | 0.532% | |
| 2/13/2024 | CIBC Asset Management Inc | 212,178 | $1.28M | 0.0% | +46.8% | 0.889% | |
| 2/1/2024 | Jennison Associates LLC | 480,828 | $2.90M | 0.0% | N/A | 2.015% | |
| 11/22/2023 | Polar Capital Holdings Plc | 1,000,000 | $5.56M | 0.0% | N/A | 4.191% | |
| 11/15/2023 | Laurion Capital Management LP | 26,478 | $147K | 0.0% | -14.4% | 0.111% | |
| 11/13/2023 | FMR LLC | 2,113,073 | $11.75M | 0.0% | -17.8% | 8.856% | |
| 11/1/2023 | Bourgeon Capital Management LLC | 7,000 | $39K | 0.0% | N/A | 0.030% | |
| 10/27/2023 | TD Asset Management Inc | 121,422 | $675K | 0.0% | +149.8% | 0.528% | |
| 8/14/2023 | Prosight Management LP | 734,897 | $5.39M | 1.7% | -18.4% | 3.198% | |
| 8/9/2023 | TD Asset Management Inc | 48,611 | $357K | 0.0% | +29.2% | 0.212% | |
| 8/4/2023 | American International Group Inc. | 7,498 | $55K | 0.0% | N/A | 0.033% | |
| 8/2/2023 | Bank of Montreal Can | 15,488 | $126K | 0.0% | N/A | 0.067% | |
| 5/15/2023 | Farallon Capital Management LLC | 1,560,500 | $5.29M | 0.0% | +92.5% | 6.795% | |
| 5/12/2023 | Prosight Management LP | 900,600 | $3.61M | 1.7% | N/A | 3.922% | |
| 5/9/2023 | Integral Health Asset Management LLC | 582,000 | $2.33M | 0.5% | +139.5% | 2.534% | |
| 4/17/2023 | Bourgeon Capital Management LLC | 49,855 | $200K | 0.0% | +1,324.4% | 0.217% | |
| 11/14/2022 | Cormorant Asset Management LP | 2,118,283 | $7.88M | 0.6% | -6.8% | 15.592% | |
| 11/14/2022 | Integral Health Asset Management LLC | 110,000 | $409K | 0.1% | +91.9% | 0.810% | |
| 8/3/2022 | Integral Health Asset Management LLC | 57,335 | $177K | 0.0% | +20.5% | 0.422% | |
| 5/12/2022 | Integral Health Asset Management LLC | 47,600 | $254K | 0.1% | +58.7% | 0.350% | |
| 5/10/2022 | TD Asset Management Inc. | 37,624 | $195K | 0.0% | -26.0% | 0.277% | |
| 4/25/2022 | Bailard Inc. | 21,200 | $110K | 0.0% | N/A | 0.156% | |
| 2/10/2022 | Citigroup Inc. | 200,000 | $968K | 0.0% | N/A | 1.472% | |
| 2/10/2022 | TD Asset Management Inc. | 50,850 | $246K | 0.0% | -11.2% | 0.374% | |
| 11/15/2021 | Veritable L.P. | 20,534 | $182K | 0.0% | N/A | 0.151% | |
| 11/9/2021 | TD Asset Management Inc. | 57,275 | $510K | 0.0% | +237.1% | 0.421% | |
| 8/17/2021 | Price T Rowe Associates Inc. MD | 2,287,289 | $20.11M | 0.0% | -0.7% | 16.836% | |
| 8/16/2021 | Alyeska Investment Group L.P. | 85,360 | $778K | 0.0% | -31.7% | 0.628% | |
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| 8/13/2021 | Renaissance Technologies LLC | 10,400 | $95K | 0.0% | N/A | 0.077% | |
| 8/13/2021 | Laurion Capital Management LP | 20,918 | $191K | 0.0% | -14.3% | 0.154% | |
| 8/13/2021 | Integral Health Asset Management LLC | 60,000 | $548K | 0.1% | +100.0% | 0.442% | |
| 8/13/2021 | Vanguard Group Inc. | 165,545 | $1.51M | 0.0% | +201.0% | 1.218% | |
| 8/13/2021 | FMR LLC | 2,037,831 | $18.59M | 0.0% | +2.2% | 14.999% | |
| 5/27/2021 | Davidson Kempner Capital Management LP | 25,000 | $405K | 0.0% | N/A | 0.184% | |
| 5/18/2021 | Millennium Management LLC | 190,349 | $3.11M | 0.0% | N/A | 1.401% | |
| 5/18/2021 | Orbimed Advisors LLC | 300,000 | $4.91M | 0.0% | N/A | 2.208% | |
| 5/18/2021 | Alyeska Investment Group L.P. | 125,000 | $2.05M | 0.0% | N/A | 0.920% | |
| 5/18/2021 | Cormorant Asset Management LP | 2,356,000 | $37.19M | 0.8% | N/A | 17.341% | |
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