Scilex (SCLX) Stock Price, News & Analysis

Company Overview

Scilex Holding Company focuses on acquiring, developing, and commercializing non-opioid pain management products for the treatment of acute and chronic pain. Its commercial products include ZTlido (lidocaine topical system) 1.8% (ZTlido), a prescription lidocaine topical product for the relief of neuropathic pain associated with postherpetic neuralgia (PHN), which is a form of post-shingles nerve pain; ELYXYB, a ready-to-use oral solution for the acute treatment of migraine with or without aura in adults; and GLOPERBA, a liquid oral version of the anti-gout medicine colchicine indicated for the prophylaxis of painful gout flares in adults. The company is also developing three product candidates, including SP-102 (10 mg dexamethasone sodium phosphate viscous gel) (SEMDEXA), a novel viscous gel formulation of a used corticosteroid for epidural injections, which has completed a Phase 3 study to treat lumbosacral radicular pain or sciatica; SP-103 (lidocaine topical system) 5.4% (SP-103), a formulation of ZTlido for the treatment of chronic neck pain and low back pain (LBP) that has completed a Phase 2 trial; and SP-104 (4.5 mg low-dose naltrexone hydrochloride delayed-release capsules) (SP-104), a novel low-dose delayed-release naltrexone hydrochloride, which has completed Phase 1 trials for the treatment of fibromyalgia. The company is headquartered in Palo Alto, California.

Key Stats

• Today's Range: $17.32 to $20.41
• 50-Day Range: $4.64 to $21.00
• 52-Week Range: $3.60 to $45.15
• Volume: 465,891 shs
• Average Volume: 313,464 shs
• Market Capitalization: $131.34 million
• P/E Ratio: N/A
• Dividend Yield: N/A
• Price Target: $455.00
• Consensus Rating: Moderate Buy

Scilex Stock Analysis - MarketRank™

Scilex scored higher than 49% of companies evaluated by MarketBeat, and ranked 560th out of 932 stocks in the medical sector. Scores are calculated by averaging available category scores, with extra weight given to analysis and valuation.

Analyst's Opinion

• Score: 3.3 / 5
• Analyst Rating: Moderate Buy

Consensus Rating

Scilex has received a consensus rating of Moderate Buy. The company's average rating score is 2.50, and is based on 2 buy ratings, 2 hold ratings, and no sell ratings.

Amount of Analyst Coverage

Scilex has received no research coverage in the past 90 days.

Earnings and Valuation

• Score: 0.6 / 5
• Proj. Earnings Growth: Growing

Earnings Growth

Earnings for Scilex are expected to grow in the coming year, from ($0.57) to ($0.41) per share.

Price to Earnings Ratio vs. the Market

The P/E ratio of Scilex is -0.65, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Price to Earnings Ratio vs. Sector

The P/E ratio of Scilex is -0.65, which means that its earnings are negative and its P/E ratio cannot be compared to companies with positive earnings.

Short Interest

• Score: 2.0 / 5
• Short Interest Level: Bearish

Percentage of Shares Shorted

8.76% of the float of Scilex has been sold short.

Short Interest Ratio / Days to Cover

Scilex has a short interest ratio ("days to cover") of 2.7, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Scilex has recently increased by 4.02%, indicating that investor sentiment is decreasing.

Dividend

• Score: 0.0 / 5
• Dividend Strength: N/A

Dividend Yield

Scilex does not currently pay a dividend.

Dividend Growth

Scilex does not have a long track record of dividend growth.

Sustainability and ESG

• Score: N/A
• Environmental Score: N/A

Percentage of Shares Shorted

8.76% of the float of Scilex has been sold short.

Short Interest Ratio / Days to Cover

Scilex has a short interest ratio ("days to cover") of 2.7, which is generally considered an acceptable ratio of short interest to trading volume.

Change versus previous month

Short interest in Scilex has recently increased by 4.02%, indicating that investor sentiment is decreasing.

News and Social Media

• Score: 3.1 / 5
• News Sentiment: 0.49

News Sentiment

Scilex has a news sentiment score of 0.49. This score is calculated as an average of sentiment of articles about the company over the last seven days and ranges from 2 (good news) to -2 (bad news). This is a lower news sentiment than the 0.66 average news sentiment score of Medical companies.

News Coverage This Week

MarketBeat has tracked 4 news articles for Scilex this week, compared to 2 articles on an average week.

Search Interest

21 people have searched for SCLX on MarketBeat in the last 30 days. This is an increase of 200% compared to the previous 30 days.

MarketBeat Follows

6 people have added Scilex to their MarketBeat watchlist in the last 30 days. This is an increase of 200% compared to the previous 30 days.

Company Ownership

• Score: 1.7 / 5
• Insider Trading: N/A

Insider Buying vs. Insider Selling

In the past three months, Scilex insiders have not sold or bought any company stock.

Percentage Held by Insiders

Only 7.94% of the stock of Scilex is held by insiders.

Percentage Held by Institutions

69.67% of the stock of Scilex is held by institutions. High institutional ownership can be a signal of strong market trust in this company.

SCLX Stock Analysis - Frequently Asked Questions

How have SCLX shares performed this year?

Scilex's stock was trading at $14.9240 on January 1st, 2025. Since then, SCLX stock has increased by 26.4% and is now trading at $18.87.

How were Scilex's earnings last quarter?

Scilex Holding Company (NASDAQ:SCLX) released its quarterly earnings data on Wednesday, August, 13th. The company reported ($7.42) earnings per share for the quarter, missing the consensus estimate of ($4.55) by $2.87. The business had revenue of $9.90 million for the quarter, compared to the consensus estimate of $26.25 million.

When did Scilex's stock split?

Shares of Scilex reverse split before market open on Tuesday, April 15th 2025.The 1-35 reverse split was announced on Friday, April 11th 2025. The number of shares owned by shareholders was adjusted after the closing bell on Monday, April 14th 2025. An investor that had 100 shares of stock prior to the reverse split would have 3 shares after the split.

Who are Scilex's major shareholders?

Scilex's top institutional investors include Geode Capital Management LLC (0.89%), Rafferty Asset Management LLC (0.25%), Norges Bank (0.20%) and Bank of America Corp DE (0.14%). Insiders that own company stock include Henry Ji, Jaisim Shah, Jay Chun, Yue Alexander Wu and Stephen Hoi Ma.
View institutional ownership trends.

How do I buy shares of Scilex?

Shares of SCLX stock can be purchased through any online brokerage account. Popular online brokerages with access to the U.S. stock market include Charles Schwab, E*TRADE, Fidelity, and Vanguard Brokerage Services.

What other stocks do shareholders of Scilex own?

Based on aggregate information from My MarketBeat watchlists, some other companies that Scilex investors own include Rigetti Computing (RGTI), Pfizer (PFE), BioNTech (BNTX), Hertz Global (HTZ), BlackBerry (BB).

Company Calendar

• Last Earnings: 8/13/2025
• Today: 8/23/2025
• Fiscal Year End: 12/31/2025

Industry, Sector and Symbol

• Stock Exchange: NASDAQ
• Sector: Medical
• Industry: MED - BIOMED/GENE
• Sub-Industry: Pharmaceutical Products
• Current Symbol: NASDAQ:SCLX
• CIK: 1820190
• Web: www.scilexholding.com
• Phone: 650-516-4310
• Fax: N/A
• Employees: 80
• Year Founded: N/A

Price Target and Rating

• Average Price Target for Scilex: $455.00
• High Price Target: $630.00
• Low Price Target: $245.00
• Potential Upside/Downside: +2,311.2%
• Consensus Rating: Moderate Buy
• Rating Score (0-4): 2.50
• Research Coverage: 4 Analysts

Profitability

• EPS (Trailing Twelve Months): ($29.02)
• Trailing P/E Ratio: N/A
• Forward P/E Ratio: N/A
• P/E Growth: N/A
• Net Income: -$72.81 million
• Net Margins: -179.12%
• Pretax Margin: -183.01%
• Return on Equity: N/A
• Return on Assets: -109.95%

Debt

• Debt-to-Equity Ratio: N/A
• Current Ratio: 0.11
• Quick Ratio: 0.10

Sales & Book Value

• Annual Sales: $56.59 million
• Price / Sales: 2.32
• Cash Flow: N/A
• Price / Cash Flow: N/A
• Book Value: ($35.80) per share
• Price / Book: -0.53

Miscellaneous

• Outstanding Shares: 6,960,000
• Free Float: 6,404,000
• Market Cap: $131.34 million
• Optionable: Optionable
• Beta: 1.32