| 11/19/2024 | Barclays PLC | 79,740 | $980K | 0.0% | +145.3% | 0.151% | |
| 11/16/2024 | Geode Capital Management LLC | 870,831 | $10.71M | 0.0% | +9.7% | 1.644% | |
| 11/15/2024 | Barclays PLC | 79,740 | $980K | 0.0% | +145.3% | 0.151% | |
| 11/15/2024 | Jane Street Group LLC | 330,442 | $4.06M | 0.0% | +338.2% | 0.624% | |
| 11/15/2024 | Wellington Management Group LLP | 136,975 | $1.68M | 0.0% | -4.6% | 0.259% | |
| 11/15/2024 | State Street Corp | 1,728,888 | $21.25M | 0.0% | +8.6% | 3.264% | |
|
| 11/15/2024 | RTW Investments LP | 4,652,285 | $57.18M | 0.8% | +10.1% | 8.783% | |
| 11/15/2024 | Redmile Group LLC | 4,713,509 | $57.93M | 3.4% | -0.2% | 8.898% | |
| 11/15/2024 | Checkpoint Capital L.P. | 157,514 | $1.94M | 1.0% | N/A | 0.297% | |
| 11/14/2024 | UBS AM a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 42,692 | $525K | 0.0% | -25.6% | 0.081% | |
| 11/13/2024 | BNP Paribas Financial Markets | 76,154 | $936K | 0.0% | +1,589.7% | 0.144% | |
| 11/13/2024 | FMR LLC | 322,949 | $3.97M | 0.0% | -18.9% | 0.610% | |
| 11/12/2024 | Charles Schwab Investment Management Inc. | 316,134 | $3.89M | 0.0% | +9.3% | 0.597% | |
| 11/9/2024 | Intech Investment Management LLC | 13,052 | $160K | 0.0% | N/A | 0.025% | |
| 11/4/2024 | Los Angeles Capital Management LLC | 103,005 | $1.27M | 0.0% | +54.3% | 0.196% | |
| 11/2/2024 | Mesirow Financial Investment Management Inc. | 15,604 | $192K | 0.0% | N/A | 0.030% | |
| 10/23/2024 | Skorpios Trust | 8,906,181 | $109.46M | 99.8% | -17.9% | 16.916% | |
| 10/23/2024 | Assenagon Asset Management S.A. | 1,312,479 | $16.13M | 0.0% | -10.6% | 2.493% | |
| 10/3/2024 | SG Americas Securities LLC | 14,917 | $183K | 0.0% | -78.3% | 0.029% | |
| 9/20/2024 | Healthcare of Ontario Pension Plan Trust Fund | 1,387,200 | $18.74M | 0.1% | +426.1% | 2.635% | |
| 9/4/2024 | Ghisallo Capital Management LLC | 15,000 | $203K | 0.0% | -50.0% | 0.028% | |
| 8/15/2024 | Lynx1 Capital Management LP | 5,185,191 | $70.05M | 25.3% | +40.3% | 9.848% | |
| 8/15/2024 | The Manufacturers Life Insurance Company | 13,964 | $189K | 0.0% | +16.7% | 0.027% | |
| 8/15/2024 | Millennium Management LLC | 289,067 | $3.91M | 0.0% | +528.6% | 0.549% | |
| 8/14/2024 | Squarepoint Ops LLC | 15,042 | $203K | 0.0% | -70.6% | 0.029% | |
| 8/14/2024 | Marshall Wace LLP | 1,161,037 | $15.69M | 0.0% | +550.1% | 2.205% | |
| 8/14/2024 | Logos Global Management LP | 1,050,000 | $14.19M | 1.1% | N/A | 1.994% | |
| 8/14/2024 | Profund Advisors LLC | 14,893 | $201K | 0.0% | N/A | 0.028% | |
| 8/9/2024 | Renaissance Technologies LLC | 11,200 | $151K | 0.0% | -41.4% | 0.021% | |
| 8/9/2024 | Dimensional Fund Advisors LP | 191,360 | $2.59M | 0.0% | -12.9% | 0.367% | |
| 8/8/2024 | American Century Companies Inc. | 59,149 | $799K | 0.0% | +99.4% | 0.113% | |
| 8/6/2024 | Quest Partners LLC | 2,110 | $29K | 0.0% | N/A | 0.004% | |
| 8/6/2024 | Los Angeles Capital Management LLC | 66,765 | $902K | 0.0% | +7.2% | 0.128% | |
| 8/1/2024 | Rhumbline Advisers | 47,860 | $647K | 0.0% | +14.3% | 0.092% | |
| 7/29/2024 | Zurcher Kantonalbank Zurich Cantonalbank | 9,129 | $123K | 0.0% | N/A | 0.018% | |
| 7/26/2024 | Bank of New York Mellon Corp | 115,892 | $1.57M | 0.0% | +28.9% | 0.222% | |
| 7/20/2024 | Nisa Investment Advisors LLC | 2,989 | $40K | 0.0% | +53.2% | 0.006% | |
| 7/18/2024 | Assenagon Asset Management S.A. | 1,468,202 | $19.84M | 0.0% | N/A | 2.817% | |
| 7/12/2024 | SG Americas Securities LLC | 68,601 | $927K | 0.0% | +610.3% | 0.132% | |
| 5/30/2024 | Lynx1 Capital Management LP | 3,696,820 | $49.91M | 12.9% | +25.0% | 7.093% | |
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| 5/17/2024 | Artal Group S.A. | 300,000 | $4.05M | 0.1% | N/A | 0.576% | |
| 5/17/2024 | Ikarian Capital LLC | 6,816 | $92K | 0.0% | -43.7% | 0.013% | |
| 5/16/2024 | California State Teachers Retirement System | 2,803 | $38K | 0.0% | -38.3% | 0.005% | |
| 5/16/2024 | Jacobs Levy Equity Management Inc. | 47,912 | $647K | 0.0% | -71.5% | 0.092% | |
| 5/16/2024 | Redmile Group LLC | 5,073,049 | $68.49M | 2.5% | +93.2% | 9.733% | |
| 5/15/2024 | Baker BROS. Advisors LP | 3,368,443 | $45.47M | 0.6% | +65.9% | 6.463% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 31,431 | $425K | 0.0% | +5.5% | 0.060% | |
| 5/15/2024 | Lazard Asset Management LLC | 3,710 | $49K | 0.0% | -35.8% | 0.007% | |
| 5/14/2024 | Healthcare of Ontario Pension Plan Trust Fund | 263,700 | $3.56M | 0.0% | +10.2% | 0.506% | |
| 5/10/2024 | Vanguard Group Inc. | 1,715,554 | $23.16M | 0.0% | +4.1% | 3.292% | |
| 5/9/2024 | State Board of Administration of Florida Retirement System | 10,473 | $141K | 0.0% | N/A | 0.020% | |
| 5/7/2024 | Susquehanna Portfolio Strategies LLC | 43,424 | $586K | 0.0% | -3.7% | 0.083% | |
| 5/7/2024 | SG Americas Securities LLC | 9,658 | $130K | 0.0% | -36.0% | 0.019% | |
| 5/3/2024 | GSA Capital Partners LLP | 97,508 | $1.32M | 0.1% | -4.5% | 0.187% | |
| 5/2/2024 | Chase Investment Counsel Corp | 20,738 | $279K | 0.1% | N/A | 0.040% | |
| 5/1/2024 | BNP Paribas Financial Markets | 14,330 | $193K | 0.0% | +86.2% | 0.027% | |
| 5/1/2024 | Mirae Asset Global Investments Co. Ltd. | 90,663 | $1.22M | 0.0% | N/A | 0.174% | |
| 4/29/2024 | Principal Financial Group Inc. | 10,451 | $141K | 0.0% | -13.2% | 0.020% | |
| 4/23/2024 | Seven Grand Managers LLC | 30,000 | $405K | 0.2% | N/A | 0.065% | |
| 2/15/2024 | Birchview Capital LP | 210,000 | $1.11M | 0.9% | +147.1% | 0.470% | |
| 2/14/2024 | RTW Investments LP | 4,131,045 | $21.73M | 0.3% | -5.9% | 9.252% | |
| 2/9/2024 | Trexquant Investment LP | 39,800 | $209K | 0.0% | -68.8% | 0.089% | |
| 2/6/2024 | Los Angeles Capital Management LLC | 62,257 | $327K | 0.0% | +30.4% | 0.139% | |
| 2/2/2024 | Simplex Trading LLC | 7,979 | $41K | 0.0% | -35.0% | 0.018% | |
| 12/19/2023 | Public Employees Retirement System of Ohio | 16,335 | $64K | 0.0% | N/A | 0.037% | |
| 11/15/2023 | GSA Capital Partners LLP | 348,069 | $1.37M | 0.1% | +514.7% | 0.780% | |
| 11/15/2023 | Redmile Group LLC | 3,872,696 | $15.26M | 0.7% | -2.1% | 8.673% | |
| 11/14/2023 | Corton Capital Inc. | 14,749 | $58K | 0.0% | N/A | 0.033% | |
| 11/14/2023 | Sherbrooke Park Advisers LLC | 12,295 | $48K | 0.0% | N/A | 0.028% | |
| 11/14/2023 | Lynx1 Capital Management LP | 1,710,154 | $6.74M | 4.5% | N/A | 3.830% | |
| 11/14/2023 | Trexquant Investment LP | 127,581 | $503K | 0.0% | +166.9% | 0.286% | |
| 11/13/2023 | Algert Global LLC | 16,550 | $65K | 0.0% | -52.5% | 0.037% | |
| 11/13/2023 | Healthcare of Ontario Pension Plan Trust Fund | 239,300 | $943K | 0.0% | -15.1% | 0.536% | |
| 11/8/2023 | Dorsey & Whitney Trust CO LLC | 10,815 | $43K | 0.0% | N/A | 0.024% | |
| 11/7/2023 | Barclays PLC | 8,440 | $33K | 0.0% | -43.1% | 0.019% | |
| 10/26/2023 | Mirae Asset Global Investments Co. Ltd. | 146,076 | $576K | 0.0% | +9.3% | 0.330% | |
| 10/24/2023 | Bank of New York Mellon Corp | 107,254 | $423K | 0.0% | +2.8% | 0.242% | |
| 10/13/2023 | SG Americas Securities LLC | 13,557 | $53K | 0.0% | N/A | 0.031% | |
| 9/21/2023 | Barclays PLC | 14,829 | $157K | 0.0% | -35.1% | 0.034% | |
| 8/14/2023 | Driehaus Capital Management LLC | 102,489 | $1.09M | 0.0% | N/A | 0.232% | |
| 8/14/2023 | Granahan Investment Management LLC | 532,880 | $5.67M | 0.2% | -11.7% | 1.204% | |
| 8/11/2023 | M28 Capital Management LP | 346,190 | $3.68M | 4.9% | -35.0% | 0.782% | |
| 8/11/2023 | Trexquant Investment LP | 47,796 | $508K | 0.0% | -62.0% | 0.108% | |
| 8/10/2023 | Mirae Asset Global Investments Co. Ltd. | 133,598 | $1.42M | 0.0% | +44.7% | 0.302% | |
| 8/7/2023 | Principal Financial Group Inc. | 11,388 | $121K | 0.0% | N/A | 0.026% | |
| 8/7/2023 | Cowen AND Company LLC | 3,721,659 | $39.56M | 3.3% | +13.5% | 8.422% | |
| 8/4/2023 | American International Group Inc. | 13,277 | $141K | 0.0% | +22.6% | 0.030% | |
| 8/3/2023 | Los Angeles Capital Management LLC | 49,077 | $522K | 0.0% | +25.7% | 0.111% | |
| 5/16/2023 | Baker BROS. Advisors LP | 2,115,416 | $17.62M | 0.1% | +90.8% | 4.787% | |
| 5/15/2023 | RTW Investments LP | 4,390,558 | $36.57M | 0.8% | +13.4% | 9.936% | |
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| 5/15/2023 | Granahan Investment Management LLC | 603,524 | $5.03M | 0.2% | +9.7% | 1.366% | |
| 5/10/2023 | Simplify Asset Management Inc. | 122,796 | $1.02M | 0.1% | N/A | 0.278% | |
| 5/10/2023 | Connor Clark & Lunn Investment Management Ltd. | 51,935 | $433K | 0.0% | -7.5% | 0.118% | |
| 5/9/2023 | Cowen AND Company LLC | 3,279,142 | $27.32M | 3.2% | +338.3% | 7.421% | |
| 5/4/2023 | Los Angeles Capital Management LLC | 39,055 | $325K | 0.0% | -3.4% | 0.088% | |
| 2/14/2023 | Granahan Investment Management LLC | 550,219 | $5.08M | 0.2% | +112.4% | 1.396% | |
| 2/13/2023 | GSA Capital Partners LLP | 71,572 | $661K | 0.1% | -4.7% | 0.182% | |
| 2/10/2023 | M28 Capital Management LP | 482,890 | $4.46M | 4.2% | -7.6% | 1.225% | |
| 2/10/2023 | Connor Clark & Lunn Investment Management Ltd. | 56,125 | $518K | 0.0% | +39.5% | 0.142% | |
| 2/10/2023 | HRT Financial LP | 108,282 | $999K | 0.0% | +82.5% | 0.275% | |
