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Compare stocks with our powerful stock comparison tool. Analyze fundamentals, price performance, and key financial indicators to make informed investment decisions. Our tool lets you compare up to ten stocks side by side based on Performance Charts, Price & Volume, MarketRank™, Analyst Ratings, Sales & Book Value, Profitability & Earnings, Dividends, Debt, Ownership, Headlines, and more. Simply enter up to ten stock symbols (e.g., BAC, JPM, WFC, C, GS) to get started and uncover top investment opportunities.

Comparative Price Performance Over Time

Compare Price & Volume

Company	Current Price	50-Day Moving Average	52-Week Range	Market Cap	Beta	Avg. Volume	Today's Volume
CNTA Centessa Pharmaceuticals	$17.28 -0.3%	$14.98	$9.60 ▼ $19.09	$2.31B	1.48	964,706 shs	692,859 shs
IRON Disc Medicine	$58.72 +0.9%	$56.44	$30.82 ▼ $68.73	$2.04B	0.77	402,861 shs	249,699 shs
MESO Mesoblast	$15.01 -0.9%	$13.18	$6.00 ▼ $22.00	$1.92B	2.4	277,021 shs	149,989 shs
OPT Opthea	$3.41	$3.41	$1.79 ▼ $6.30	$524.83M	1.17	N/A	N/A

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Compare Price Performance

Company	1-Day Performance	7-Day Performance	30-Day Performance	90-Day Performance	1-Year Performance
CNTA Centessa Pharmaceuticals	-1.42%	+1.34%	+10.52%	+35.26%	+40.86%
IRON Disc Medicine	-1.12%	-1.44%	+0.71%	+19.00%	+18.11%
MESO Mesoblast	-4.96%	+1.95%	-3.07%	+34.46%	+126.31%
OPT Opthea	0.00%	0.00%	0.00%	0.00%	+24.45%

Compare MarketRank™

Company	Overall Score	Analyst's Opinion	Short Interest Score	News and Social Media Sentiment	Company Ownership	Earnings & Valuation
CNTA Centessa Pharmaceuticals	2.1625 of 5 stars	3.5	1.0	1.5	2.5	0.6
IRON Disc Medicine	3.6024 of 5 stars	4.5	3.0	3.2	2.5	0.0
MESO Mesoblast	2.0897 of 5 stars	2.6	4.0	2.6	0.8	0.6
OPT Opthea	0.3657 of 5 stars	1.1	0.0	2.1	0.8	0.6

Compare Analyst Forecasts

Company	Consensus Rating Score	Consensus Rating	Consensus Price Target	% Upside from Current Price
CNTA Centessa Pharmaceuticals	3.00	Buy	$28.10	62.62% Upside
IRON Disc Medicine	3.08	Buy	$96.18	63.80% Upside
MESO Mesoblast	3.20	Buy	$18.00	19.92% Upside
OPT Opthea	2.17	Hold	$1.33	-60.90% Downside

Current Analyst Ratings Breakdown

Latest OPT, IRON, MESO, and CNTA Analyst Ratings

Date	Company	Brokerage	Action	Rating	Price Target
8/18/2025	IRON Disc Medicine	Morgan Stanley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Boost Price Target	Overweight ➝ Overweight	$85.00 ➝ $90.00
8/12/2025	CNTA Centessa Pharmaceuticals	Chardan Capital Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$30.00
8/5/2025	MESO Mesoblast	Canaccord Genuity Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Upgrade	Strong-Buy
7/30/2025	CNTA Centessa Pharmaceuticals	Chardan Capital Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$30.00
7/21/2025	CNTA Centessa Pharmaceuticals	Truist Financial Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy	$30.00
7/21/2025	IRON Disc Medicine	Wedbush Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Outperform	$90.00
7/21/2025	IRON Disc Medicine	Truist Financial Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Buy	$86.00
7/18/2025	MESO Mesoblast	Jefferies Financial Group Subscribe to MarketBeat All Access for the recommendation accuracy rating	Downgrade	Buy ➝ Hold
7/3/2025	IRON Disc Medicine	Morgan Stanley Subscribe to MarketBeat All Access for the recommendation accuracy rating	Initiated Coverage	Overweight	$85.00
7/3/2025	IRON Disc Medicine	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$118.00
6/17/2025	IRON Disc Medicine	HC Wainwright Subscribe to MarketBeat All Access for the recommendation accuracy rating	Reiterated Rating	Buy ➝ Buy	$118.00

(Data available from 8/20/2022 forward. View 10+ years of historical ratings with our analyst ratings screener.)

Compare Sales & Book Value

Company	Annual Revenue	Price/Sales	Cashflow	Price/Cash	Book Value	Price/Book
CNTA Centessa Pharmaceuticals	$15M	154.27	N/A	N/A	$2.58 per share	6.70
IRON Disc Medicine	N/A	N/A	N/A	N/A	$17.67 per share	N/A
MESO Mesoblast	$5.90M	325.64	N/A	N/A	$4.21 per share	3.57
OPT Opthea	$120K	4,373.61	N/A	N/A	($0.56) per share	-6.09

Compare Profitability & Earnings

Company	Net Income	EPS	Trailing P/E Ratio	Forward P/E Ratio	P/E Growth	Net Margins	Return on Equity (ROE)	Return on Assets (ROA)	Next Earnings Date
CNTA Centessa Pharmaceuticals	-$235.76M	-$1.79	N/A	N/A	N/A	N/A	-40.39%	-29.87%	N/A
IRON Disc Medicine	-$109.36M	-$4.47	N/A	N/A	N/A	N/A	-26.60%	-24.58%	N/A
MESO Mesoblast	-$87.96M	N/A	0.00	N/A	N/A	N/A	N/A	N/A	8/27/2025 (Estimated)
OPT Opthea	-$220.24M	N/A	0.00	N/A	N/A	N/A	N/A	N/A	8/29/2025 (Estimated)

Latest OPT, IRON, MESO, and CNTA Earnings

Date	Quarter	Company	Consensus Estimate	Reported EPS	Beat/Miss	Gap EPS	Revenue Estimate	Actual Revenue
8/27/2025	H2 2025	MESO Mesoblast	-$0.20	N/A	N/A	N/A	$7.48 million	N/A
8/12/2025	Q2 2025	CNTA Centessa Pharmaceuticals	-$0.35	-$0.38	-$0.03	-$0.38	$0.63 million	N/A
8/7/2025	Q2 2025	IRON Disc Medicine	-$1.17	-$1.58	-$0.41	-$1.58	N/A	N/A

Compare Dividends

Company	Annual Payout	Dividend Yield	3-Year Dividend Growth	Payout Ratio	Years of Consecutive Growth
CNTA Centessa Pharmaceuticals	N/A	N/A	N/A	N/A	N/A
IRON Disc Medicine	N/A	N/A	N/A	N/A	N/A
MESO Mesoblast	N/A	N/A	N/A	N/A	N/A
OPT Opthea	N/A	N/A	N/A	N/A	N/A

Compare Debt

Company	Debt-to-Equity Ratio	Current Ratio	Quick Ratio
CNTA Centessa Pharmaceuticals	0.32	10.11	10.12
IRON Disc Medicine	0.05	32.11	32.11
MESO Mesoblast	0.22	0.96	0.63
OPT Opthea	N/A	1.57	N/A

Compare Ownership

Institutional Ownership

Company	Institutional Ownership
CNTA Centessa Pharmaceuticals	82.01%
IRON Disc Medicine	83.70%
MESO Mesoblast	1.43%
OPT Opthea	55.95%

Insider Ownership

Company	Insider Ownership
CNTA Centessa Pharmaceuticals	7.09%
IRON Disc Medicine	3.64%
MESO Mesoblast	18.80%
OPT Opthea	3.20%

Compare Miscellaneous Stats

Company	Employees	Shares Outstanding	Free Float	Optionable
CNTA Centessa Pharmaceuticals	200	133.91 million	124.42 million	Optionable
IRON Disc Medicine	30	34.77 million	33.50 million	Not Optionable
MESO Mesoblast	80	128.00 million	103.93 million	Optionable
OPT Opthea	8	153.91 million	148.99 million	Not Optionable

OPT, IRON, MESO, and CNTA Headlines

Recent News About These Companies

Opthea Limited Provides Corporate Update in Investor Presentation

August 20 at 2:02 AM | msn.com

Opthea parts with CEO, lays off over 80% of company

August 19 at 9:01 PM | ophthalmologytimes.comO

Opthea Provides Corporate Update

August 18 at 7:00 PM | globenewswire.com

Regal Partners Ltd Has $17.71 Million Position in Opthea Limited Unsponsored ADR (NASDAQ:OPT)

August 14, 2025 | marketbeat.com

Opthea (NASDAQ:OPT) Stock Price Up 7.2% - What's Next?

July 26, 2025 | marketbeat.com

Biocurious: Dimerix could be riding big and beautiful kidney drug success earlier than expected

July 2, 2025 | msn.com

Opthea Faces Leadership Changes Amidst Clinical Trial Setbacks

June 1, 2025 | tipranks.com

Biotech Dimerix lands $940m licensing deal for kidney drug sales

May 1, 2025 | afr.com

Phil King’s Regal successfully bets against Tesla, Nvidia

May 1, 2025 | afr.com

'No one is happy': Regal stockpickers face financial hit after Opthea blow up

April 21, 2025 | capitalbrief.comC

Regal’s King says his hedge funds will recover from March madness

April 16, 2025 | afr.com

Regal: Don’t catch the falling knife, wait for it to stick in the floor

April 16, 2025 | msn.com

Opthea to lay off approximately 65% of company

April 10, 2025 | ophthalmologytimes.comO

Opthea lays off 65% of staff after back-to-back phase 3 eye disease flops

April 10, 2025 | fiercebiotech.comF

BELL POTTER SECURITIES Downgrades Opthea (CKDXF)

April 9, 2025 | msn.com

BELL POTTER SECURITIES Downgrades Opthea Limited - Depositary Receipt () (OPT)

April 9, 2025 | msn.com

ASX drops as US jumbo China tariff takes effect

April 9, 2025 | afr.com

Opthea Limited (CKDXF) was downgraded to a Sell Rating at Bell Potter

April 3, 2025 | markets.businessinsider.com

Phil King’s Regal writes Opthea to zero and backs off risky bets

April 2, 2025 | afr.com

Opthea Ends Development of Sozinibercept in Wet AMD

March 31, 2025 | marketwatch.com

LifeMine’s restructuring; Europe won’t renew authorization for PTC’s Duchenne drug

March 31, 2025 | endpts.comE

New MarketBeat Followers Over Time

Media Sentiment Over Time

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OPT, IRON, MESO, and CNTA Company Descriptions

Centessa Pharmaceuticals NASDAQ:CNTA

$17.28 -0.06 (-0.35%)

Closing price 04:00 PM Eastern

Extended Trading

$17.52 +0.24 (+1.41%)

As of 04:10 PM Eastern

Centessa Pharmaceuticals plc, a clinical-stage pharmaceutical company, discovers, develops, and delivers medicines for patients. Its products pipeline includes SerpinPC, an activated protein C inhibitor for the treatment of hemophilia A and B; and ORX750, an orally administered OX2R agonist for the treatment of narcolepsy and other sleep disorders. The company also develops LB101, a PD-L1xCD47 LockBody, a bi-specific monoclonal antibody for solid tumors, which is designed to selectively drive potent CD47 and CD3 effector function activity while avoiding systemic toxicity; and OX2R Agonists compounds are currently in development for the treatment of narcolepsy. In addition, its products pipeline comprises ORX750, an orally administered selective orexin receptor-2 (OX2R) agonist for the treatment of narcolepsy and other sleep disorders; and earlier-stage preclinical assets and discovery-stage programs. Centessa Pharmaceuticals plc was incorporated in 2020 and is headquartered in Altrincham, the United Kingdom.

Disc Medicine NASDAQ:IRON

$58.72 +0.54 (+0.93%)

Closing price 04:00 PM Eastern

Extended Trading

$58.70 -0.02 (-0.03%)

As of 04:04 PM Eastern

Disc Medicine, Inc., together with its subsidiaries, a clinical-stage biopharmaceutical company, engages in the discovery, development, and commercialization of novel treatments for patients suffering from serious hematologic diseases in the United States. The company has assembled a portfolio of clinical and preclinical product candidates that aim to modify fundamental biological pathways associated with the formation and function of red blood cells, primarily heme biosynthesis and iron homeostasis. Its pipeline includes bitopertin for the treatment of erythropoietic porphyrias, including erythropoietic protoporphyria, X-linked protoporphyria, and diamond-blackfan anemia; DISC-0974 for the treatment of anemia of myelofibrosis, and anemia of chronic kidney disease; and DISC-3405 for the treatment of polycythemia vera, and other hematologic disorders. The company's preclinical programs include DISC-0998, for the treatment of anemia associated with inflammatory diseases. Disc Medicine, Inc. was founded in 2017 and is headquartered in Watertown, Massachusetts.

Mesoblast NASDAQ:MESO

$15.01 -0.13 (-0.86%)

Closing price 04:00 PM Eastern

Extended Trading

$15.02 +0.02 (+0.10%)

As of 04:10 PM Eastern

Mesoblast Limited engages in the development of regenerative medicine products in Australia, the United States, Singapore, and Switzerland. The company offers products in the areas of cardiovascular, spine orthopedic disorder, oncology, hematology, and immune-mediated and inflammatory diseases. Its proprietary regenerative medicine technology platform is based on specialized cells known as mesenchymal lineage cells. The company offers Remestemcel-L that is in Phase III clinical trials for the treatment of systemic inflammatory diseases, including steroid refractory acute graft versus host disease, acute respiratory distress syndrome, and biologic refractory inflammatory bowel disease; and Remestemcel-L, which is in Phase III clinical trials to treat chronic heart failure and chronic low back pain due to degenerative disc disease. It is also developing MPC-300-IV to treat biologic refractory rheumatoid arthritis diabetic nephropathy; and MPC-25-IC for the treatment or prevention of acute myocardial infarction. It has strategic partnerships with Tasly Pharmaceutical Group to offer MPC-150-IM for heart failure and MPC-25-IC for heart attacks in China; JCR Pharmaceuticals Co. Ltd. to treat wound healing in patients with epidermolysis bullosa; and Grünenthal to develops and commercializes cell therapy for the treatment of chronic low back pain. The company was incorporated in 2004 and is headquartered in Melbourne, Australia.

Opthea NASDAQ:OPT

$3.41 0.00 (0.00%)

As of 08/19/2025

Opthea Limited, a clinical stage biopharmaceutical company, engages in the development and commercialization of therapies primarily for eye disease in Australia. The company's development activities are based on the intellectual property portfolio covering Vascular Endothelial Growth Factors (VEGF) VEGF-C, VEGF-D, and VEGF Receptor-3 for the treatment of diseases associated with blood and lymphatic vessel growth, as well as vascular leakage. Its lead product candidate is Sozinibercept (OPT 302), a soluble form of vascular endothelial growth factor receptor-3 VEGFR-3, currently under Phase 3 clinical development as a novel therapy for wet age-related macular degeneration and diabetic macular edema. The company was formerly known as Circadian Technologies Limited and changed its name to Opthea Limited in December 2015. Opthea Limited was incorporated in 1984 and is based in South Yarra, Australia.

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Comparative Price Performance Over Time