| 5/16/2024 | California State Teachers Retirement System | 11,800 | $735K | 0.0% | +37.2% | 0.048% | |
| 5/16/2024 | Janus Henderson Group PLC | 521,773 | $32.47M | 0.0% | +17.7% | 2.114% | |
| 5/16/2024 | Bain Capital Life Sciences Investors LLC | 1,317,213 | $82.01M | 6.6% | -1.2% | 5.337% | |
| 5/15/2024 | Price T Rowe Associates Inc. MD | 944,213 | $58.79M | 0.0% | +59.8% | 3.826% | |
| 5/14/2024 | StemPoint Capital LP | 60,129 | $3.74M | 1.0% | -52.4% | 0.244% | |
| 5/10/2024 | Vanguard Group Inc. | 782,751 | $48.73M | 0.0% | +2.4% | 3.243% | |
|
| 5/9/2024 | Lord Abbett & CO. LLC | 119,312 | $7.43M | 0.0% | N/A | 0.494% | |
| 5/8/2024 | Bleakley Financial Group LLC | 4,572 | $285K | 0.0% | +23.0% | 0.019% | |
| 5/8/2024 | ProShare Advisors LLC | 3,385 | $211K | 0.0% | N/A | 0.014% | |
| 5/7/2024 | Swiss National Bank | 23,800 | $1.48M | 0.0% | +50.6% | 0.099% | |
| 5/7/2024 | SG Americas Securities LLC | 2,824 | $176K | 0.0% | -69.1% | 0.012% | |
| 5/6/2024 | Atlas Venture Life Science Advisors LLC | 2,287,233 | $142.40M | 13.1% | -10.5% | 9.475% | |
| 5/2/2024 | Jennison Associates LLC | 193,240 | $12.03M | 0.0% | +349.1% | 0.800% | |
| 4/29/2024 | China Universal Asset Management Co. Ltd. | 4,641 | $289K | 0.0% | +66.2% | 0.019% | |
| 4/24/2024 | Simplicity Wealth LLC | 4,566 | $284K | 0.0% | N/A | 0.019% | |
| 3/22/2024 | PNC Financial Services Group Inc. | 10,000 | $578K | 0.0% | +149.4% | 0.041% | |
| 3/5/2024 | Wellington Management Group LLP | 177,726 | $10.27M | 0.0% | +224.6% | 0.736% | |
| 2/26/2024 | Virtu Financial LLC | 13,802 | $797K | 0.1% | N/A | 0.057% | |
| 2/26/2024 | Perceptive Advisors LLC | 1,023,045 | $59.09M | 1.3% | +14.2% | 4.238% | |
| 2/15/2024 | Parkman Healthcare Partners LLC | 92,871 | $5.36M | 0.8% | +78.4% | 0.385% | |
| 2/15/2024 | Frazier Life Sciences Management L.P. | 785,000 | $45.34M | 2.4% | +19.8% | 3.252% | |
| 2/14/2024 | Pale Fire Capital SE | 6,120 | $353K | 0.1% | N/A | 0.025% | |
| 2/13/2024 | Rafferty Asset Management LLC | 39,863 | $2.30M | 0.0% | -36.9% | 0.165% | |
| 2/12/2024 | Fiduciary Trust Co | 4,051 | $234K | 0.0% | N/A | 0.017% | |
| 2/9/2024 | Atlas Venture Life Science Advisors LLC | 2,555,172 | $147.59M | 17.6% | -6.9% | 10.585% | |
| 2/9/2024 | Franklin Resources Inc. | 221,424 | $12.79M | 0.0% | +37.5% | 0.917% | |
| 2/9/2024 | PNC Financial Services Group Inc. | 10,000 | $578K | 0.0% | +149.4% | 0.041% | |
| 2/8/2024 | Nicholas Investment Partners LP | 40,494 | $2.34M | 0.3% | N/A | 0.168% | |
| 2/8/2024 | First Turn Management LLC | 157,274 | $9.08M | 1.3% | N/A | 0.652% | |
| 2/7/2024 | Jump Financial LLC | 4,306 | $249K | 0.0% | N/A | 0.018% | |
| 2/6/2024 | Charles Schwab Investment Management Inc. | 89,725 | $5.18M | 0.0% | +6.6% | 0.372% | |
| 2/6/2024 | AJOVista LLC | 1,091 | $63K | 0.1% | N/A | 0.005% | |
| 2/6/2024 | Swiss National Bank | 15,800 | $913K | 0.0% | -9.2% | 0.065% | |
| 2/5/2024 | Victory Capital Management Inc. | 187,580 | $10.84M | 0.0% | +36.4% | 0.777% | |
| 2/1/2024 | New York State Common Retirement Fund | 9,686 | $559K | 0.0% | +194.1% | 0.040% | |
| 2/1/2024 | Jennison Associates LLC | 43,031 | $2.49M | 0.0% | N/A | 0.178% | |
| 1/30/2024 | Strs Ohio | 1,000 | $57K | 0.0% | +66.7% | 0.004% | |
| 1/29/2024 | Simplicity Solutions LLC | 3,716 | $215K | 0.0% | N/A | 0.015% | |
| 1/25/2024 | Bleakley Financial Group LLC | 3,716 | $215K | 0.0% | N/A | 0.015% | |
| 1/24/2024 | China Universal Asset Management Co. Ltd. | 2,793 | $161K | 0.0% | N/A | 0.012% | |
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| 1/16/2024 | Legato Capital Management LLC | 5,273 | $305K | 0.0% | N/A | 0.022% | |
| 1/12/2024 | SG Americas Securities LLC | 9,135 | $528K | 0.0% | N/A | 0.038% | |
| 12/18/2023 | Vanguard Group Inc. | 665,452 | $31.26M | 0.0% | +18.9% | 2.757% | |
| 12/7/2023 | Hudson Bay Capital Management LP | 42,000 | $1.97M | 0.0% | N/A | 0.174% | |
| 12/1/2023 | Wellington Management Group LLP | 54,745 | $2.57M | 0.0% | +26.5% | 0.227% | |
| 11/22/2023 | Polar Capital Holdings Plc | 546,915 | $25.69M | 0.2% | -98.7% | 2.266% | |
| 11/15/2023 | Acuta Capital Partners LLC | 138,198 | $6.49M | 4.4% | -0.9% | 0.604% | |
| 11/15/2023 | Adage Capital Partners GP L.L.C. | 1,308,405 | $61.47M | 0.1% | +12.5% | 5.719% | |
| 11/15/2023 | Alps Advisors Inc. | 16,900 | $794K | 0.0% | +16.1% | 0.074% | |
| 11/14/2023 | Schonfeld Strategic Advisors LLC | 12,700 | $597K | 0.0% | +76.4% | 0.056% | |
| 11/14/2023 | Trexquant Investment LP | 12,534 | $589K | 0.0% | N/A | 0.055% | |
| 11/14/2023 | Profund Advisors LLC | 10,552 | $496K | 0.0% | N/A | 0.046% | |
| 11/13/2023 | Atlas Venture Life Science Advisors LLC | 2,745,335 | $128.98M | 20.0% | -20.7% | 11.999% | |
| 11/13/2023 | Connor Clark & Lunn Investment Management Ltd. | 16,642 | $782K | 0.0% | N/A | 0.073% | |
| 11/13/2023 | CHI Advisors LLC | 25,000 | $1.17M | 0.4% | -80.0% | 0.109% | |
| 11/13/2023 | EAM Investors LLC | 51,111 | $2.40M | 0.5% | +8.3% | 0.223% | |
| 11/13/2023 | Invesco Ltd. | 161,213 | $7.57M | 0.0% | +45.7% | 0.705% | |
| 11/13/2023 | FMR LLC | 305,433 | $14.35M | 0.0% | -5.5% | 1.335% | |
| 11/13/2023 | Rafferty Asset Management LLC | 63,132 | $2.97M | 0.0% | N/A | 0.276% | |
| 11/9/2023 | Citigroup Inc. | 26,547 | $1.25M | 0.0% | +1,053.2% | 0.116% | |
| 11/8/2023 | Charles Schwab Investment Management Inc. | 84,200 | $3.96M | 0.0% | +309.6% | 0.368% | |
| 11/8/2023 | Swiss National Bank | 17,400 | $817K | 0.0% | N/A | 0.076% | |
| 11/7/2023 | Virtus ETF Advisers LLC | 2,014 | $95K | 0.1% | -9.2% | 0.009% | |
| 11/7/2023 | Barclays PLC | 31,561 | $1.48M | 0.0% | +1,932.3% | 0.138% | |
| 11/6/2023 | Assenagon Asset Management S.A. | 74,164 | $3.48M | 0.0% | -70.0% | 0.324% | |
| 11/6/2023 | Victory Capital Management Inc. | 137,523 | $6.46M | 0.0% | N/A | 0.601% | |
| 10/27/2023 | TD Asset Management Inc | 20,214 | $950K | 0.0% | +260.5% | 0.088% | |
| 10/26/2023 | Strs Ohio | 600 | $28K | 0.0% | N/A | 0.003% | |
| 10/24/2023 | Bank of New York Mellon Corp | 30,550 | $1.44M | 0.0% | +22.3% | 0.134% | |
| 9/21/2023 | Barclays PLC | 1,553 | $69K | 0.0% | -72.4% | 0.007% | |
| 8/24/2023 | Perceptive Advisors LLC | 742,838 | $32.98M | 1.0% | N/A | 3.752% | |
| 8/22/2023 | CHI Advisors LLC | 125,139 | $5.56M | 1.7% | N/A | 0.632% | |
| 8/15/2023 | Sphera Funds Management LTD. | 170,578 | $7.57M | 1.2% | -22.5% | 0.862% | |
| 8/15/2023 | Bain Capital Life Sciences Investors LLC | 1,332,548 | $59.17M | 6.1% | -33.1% | 6.730% | |
| 8/14/2023 | Cormorant Asset Management LP | 225,000 | $9.99M | 0.6% | N/A | 1.136% | |
| 8/14/2023 | Rock Springs Capital Management LP | 363,468 | $16.14M | 0.4% | +16.0% | 1.836% | |
| 8/14/2023 | Polar Capital Holdings Plc | 426,612 | $18.94M | 0.1% | N/A | 2.155% | |
| 8/14/2023 | Ghisallo Capital Management LLC | 20,000 | $888K | 0.1% | N/A | 0.101% | |
| 8/11/2023 | Harvard Management Co. Inc. | 8,452 | $375K | 0.0% | -66.2% | 0.043% | |
| 8/11/2023 | Franklin Resources Inc. | 157,255 | $6.98M | 0.0% | N/A | 0.794% | |
| 8/11/2023 | ExodusPoint Capital Management LP | 52,800 | $2.34M | 0.0% | -25.6% | 0.267% | |
| 8/10/2023 | Monashee Investment Management LLC | 45,000 | $2.00M | 0.5% | N/A | 0.227% | |
| 8/9/2023 | TD Asset Management Inc | 5,607 | $249K | 0.0% | N/A | 0.028% | |
| 8/4/2023 | American International Group Inc. | 3,723 | $165K | 0.0% | N/A | 0.019% | |
| 7/25/2023 | Assenagon Asset Management S.A. | 247,400 | $10.99M | 0.0% | +300.3% | 1.249% | |
| 7/13/2023 | Thompson Davis & CO. Inc. | 6,800 | $302K | 0.3% | N/A | 0.034% | |
| 5/16/2023 | Bain Capital Life Sciences Investors LLC | 1,990,914 | $42.19M | 5.3% | N/A | 10.480% | |
| 5/15/2023 | Logos Global Management LP | 525,000 | $11.13M | 1.6% | N/A | 2.763% | |
| 5/15/2023 | Ghost Tree Capital LLC | 100,000 | $2.12M | 0.6% | N/A | 0.526% | |
| 5/11/2023 | ExodusPoint Capital Management LP | 70,966 | $1.50M | 0.0% | +134.7% | 0.374% | |
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| 4/18/2023 | Assenagon Asset Management S.A. | 61,805 | $1.31M | 0.0% | -9.7% | 0.325% | |
| 4/14/2023 | BML Capital Management LLC | 208,161 | $4.41M | 3.8% | -58.4% | 1.096% | |
| 2/15/2023 | Atlas Venture Life Science Advisors LLC | 3,461,784 | $68.86M | 8.3% | N/A | 79.949% | |
| 2/15/2023 | Nantahala Capital Management LLC | 162,762 | $3.06M | 0.2% | N/A | 3.759% | |
| 2/14/2023 | Boxer Capital LLC | 130,000 | $176K | 0.0% | N/A | 3.002% | |
| 2/13/2023 | BML Capital Management LLC | 500,000 | $9.95M | 9.5% | N/A | 11.539% | |
| 2/13/2023 | Foresite Capital Management V LLC | 243,513 | $4.84M | 3.8% | N/A | 5.620% | |
| 2/10/2023 | Harvard Management Co. Inc. | 25,000 | $497K | 0.1% | N/A | 0.577% | |
| 2/8/2023 | UBS Group AG | 7,115 | $142K | 0.0% | N/A | 0.164% | |
